Erythrocyte Sodium Pump Activity in Bipolar Affective Disorder and Other Psychiatric Disorders

1989 ◽  
Vol 22 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Mabel Hokin-Neaverson ◽  
James W. Jefferson
Keyword(s):  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Sodium Pump ◽  
Bipolar Affective Disorder ◽  
Pump Activity ◽  
Erythrocyte Sodium

Molecular Genetics of Mental Disorders with Particular Reference to Affective Disorders

1997 ◽  
Vol 12 (S2) ◽  
pp. 63s-69s ◽  
Author(s):  
D Souery ◽  
O Lipp ◽  
B Mahieu ◽  
J Mendlewicz
Keyword(s):  
Mental Disorders ◽  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Molecular Genetics ◽  
Present Article ◽  
Affective Disorders ◽  
Trinucleotide Repeat ◽  
Association Studies ◽  
Bipolar Affective Disorder ◽  
Molecular Genetic

SummaryThe present article reviews the recent molecular genetic findings in affective disorders. Results of linkage and association studies are discussed in regard to the main limitations of these approaches in psychiatric disorders. On the whole, linkage and association studies contributed to the localisation of some potential vulnerability genes for Bipolar affective disorder on chromosomes 18, 5, 11, 4, 21 and X. The hypothesis of anticipation in affective disorders is also considered in light of interesting results with trinucleotide repeat mutations.

scholarly journals Evaluation of Psychiatric Disorders in Spouse of Patients with Alcohol Dependence Syndrome

2021 ◽  
pp. 1-5
Author(s):  
Mahesh Tilwani
Keyword(s):  
Alcohol Dependence ◽  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Depressive Episode ◽  
Bipolar Affective Disorder ◽  
Psychiatric Morbidity ◽  
Adjustment Disorder ◽  
International Classification Of Diseases ◽  
Psychiatric Research ◽  
Alcohol Dependence Syndrome

Background and Aim: Alcohol Dependence Syndrome has deleterious consequences not only on the patient with Alcohol Dependence Syndrome but also on the members of his family. The psychopathology in wives of patients with Alcohol Dependence Syndrome is a largely neglected area in psychiatric research. Aim of the present study was to evaluate the frequency and nature of psychiatric disorders in wives of patients with Alcohol Dependence Syndrome. Materials and Methods: A total of 177 wives, 100 wives of patients with Alcohol Dependence Syndrome and 77 wives of patients with Bipolar Affective Disorder- current episode mania were evaluated. Tools used were ICD-10 AM symptom checklist and modules for assessment of psychiatric morbidity and diagnosis was made based on The International Classification of Diseases – (Diagnostic Research Criteria DCR-10). Results: Psychiatric disorders are diagnosed in 75% of the wives of patients with alcohol dependence syndrome out of which 45% have dysthymia, 12% have mild depressive episode, 8% have adjustment disorder- prolonged depressive reaction, 5% have moderate depressive episode and 5% have anxiety disorder unspecified. Conclusion: The present study concludes that the wives of patients with Alcohol Dependence Syndrome have significant psychiatric morbidity when compared to wives of patients with Bipolar Affective Disorder-current episode mania. The most common psychiatric disorder is dysthymia.

Erythrocyte Sodium Pump Activity in Diabetes Mellitus and its Relationship to Control and Microangiopathy

1985 ◽  
Vol 69 (s12) ◽  
pp. 44P-45P
Author(s):  
P.E. Jennings ◽  
M.R. Wilkins ◽  
M.J. West ◽  
M.J. Kendall ◽  
A.H. Barnett
Keyword(s):  
Diabetes Mellitus ◽  
Sodium Pump ◽  
Pump Activity ◽  
Erythrocyte Sodium

scholarly journals Treatment Non-Compliance In Patients Suffering From Schizophrenia And Bipolar Affective Disorder (BPAD): A Comparative Study

2019 ◽  
Vol 8 (2) ◽  
pp. 20-25
Author(s):  
K. Paudel ◽  
S. Subedi
Keyword(s):  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Quality Care ◽  
Bipolar Affective Disorder ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Active Involvement ◽  
Interview Method ◽  
Adherence Scale ◽  
Bipolar Affective Disorders

 Introduction: Non-adherence to appropriately prescribed medication for psychiatric disorders prevents patients from realizing the full benefits of their treatment and negatively impacts on individuals, their families and the healthcare system. Understanding and reducing non-adherence is therefore a key challenge to quality care for patients with psychiatric disorders. This finding highlights the prevalence, consequence of non-adherence and barriers to adherence. Therefore, the main objective of this study was to determine the incidence and factors associated with medication non-compliance among patients suffering from schizophrenia and bipolar affective disorders. Material and Method: This cross-sectional study included 94 schizophrenia and 76 bipolar affective disorder subjects who were visited psychiatric OPD of tertiary level hospital and disproportionate stratified random sampling method. An anonymous socio-demographic as well contributing factor questionnaire pre tested, semi structured pro forma by interview method and a clinical proforma designed by Morisky, the 8-item Morisky Medication Adherence Scale (MMAS-8) were used for data collection. Results: The prevalence of non-compliance was 88%, the independent predictors of non-compliance were; seeking for traditional/spiritual treatment, weight gain as side effects of drugs , increased number of medication (p=0.038), beginning of medication start (p=0.057), unemployment (p=0.059), low level of insight/education (p=0.044), male as gender (p=0.016). Conclusion: Based on the outcome of the study, we recommend the development of psycho-educational programmes on compliance and the active involvement of the relatives and significant others in the management of patients of mentally ill patients.

Age and sex differences of erythrocyte sodium pump activity in normal human subjects

1977 ◽  
Vol 76 (3) ◽  
pp. 399-401 ◽  
Author(s):  
Mabel Hokin-Neaverson ◽  
David A. Spiegel ◽  
William A. Burckhardt ◽  
James W. Jefferson
Keyword(s):  
Sex Differences ◽  
Sodium Pump ◽  
Human Subjects ◽  
Pump Activity ◽  
Normal Human ◽  
Erythrocyte Sodium ◽  
Age And Sex

Duplication 15q14 → pter: a rare chromosomal abnormality underlying bipolar affective disorder

2004 ◽  
Vol 19 (3) ◽  
pp. 179-181 ◽  
Author(s):  
Andreas Reif ◽  
Wolfgang Kress ◽  
Karl Wurm ◽  
Jens Benninghoff ◽  
Bruno Pfuhlmann ◽  
...  
Keyword(s):  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Chromosomal Abnormality ◽  
Reciprocal Translocation ◽  
Bipolar Affective Disorder ◽  
Prader Willi Syndrome ◽  
Dysmorphic Features ◽  
Parietal Lobes ◽  
Pet Scanning

AbstractWe have followed up a patient with 8q24.2 → qter and 15q14 → pter duplication due to a maternal reciprocal translocation, a condition related to Prader-Willi Syndrome. Apart from dysmorphic features, the patient suffered from recurring episodes of bipolar psychosis. Interestingly, PET scanning revealed revealed prominent bilateral hypometabolism in the frontal, temporal, and parietal lobes as well as in the cerebellum. Possible implications of this rare chromosomal abnormality with regards to psychiatric disorders are discussed, with emphasis on recent evidence suggesting chromosome 15q13-15 as a susceptiblity locus for psychosis.

Relationship of Erythrocyte Sodium Pump Kinetics to Pump Activity during Pregnancy

1989 ◽  
Vol 77 (s21) ◽  
pp. 29P-29P
Author(s):  
S MacPhail ◽  
T Thomas ◽  
R Wilkindson ◽  
JM Davison ◽  
W Dunlop
Keyword(s):  
Sodium Pump ◽  
Pump Activity ◽  
Erythrocyte Sodium ◽  
Relationship Of

Premenstrual Symptoms as an Indicator of Bipolar Affective Disorder

1971 ◽  
Vol 119 (552) ◽  
pp. 527-528 ◽  
Author(s):  
James N. McClure ◽  
Theodore Reich ◽  
Richard D. Wetzel
Keyword(s):  
Depressive Disorder ◽  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Premenstrual Symptom ◽  
Premenstrual Symptoms ◽  
Affective Symptoms ◽  
Symptom Exacerbation

The premenstrual occurrence or exacerbation of affective symptoms has been noted (Dalton, 1964). This symptom exacerbation may be sufficient to require hospitalization (Dalton, 1959; Janowsky et al., 1966). Data presented by Coppen (1965) indicate that women with affective disorder are more likely to report the premenstrual symptom of depression than women with other psychiatric disorders. These findings suggest that there may be some relationship between depressive disorder and premenstrual symptoms. However, we are aware of no previous report that would suggest any relationship between premenstrual symptoms and bipolar affective disorder.

Deficiency of erythrocyte sodium pump activity in bipolar manic-depressive psychosis

Life Sciences ◽  
1974 ◽  
Vol 15 (10) ◽  
pp. 1739-1748 ◽  
Author(s):  
Mabel Hokin-Neaverson ◽  
David A. Spiegel ◽  
William C. Lewis
Keyword(s):  
Sodium Pump ◽  
Manic Depressive Psychosis ◽  
Manic Depressive ◽  
Pump Activity ◽  
Erythrocyte Sodium
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