A 13-Year Study of Antimicrobial Susceptibility of Common Gram-Negative Bacteria Isolated from the Bloodstream in a Teaching Hospital

Chemotherapy ◽  
2000 ◽  
Vol 47 (1) ◽  
pp. 29-38 ◽  
Author(s):  
Thomas K.W. Ling ◽  
Thomas K.W. Ling ◽  
Esther Y.M. Liu ◽  
Esther Y.M. Liu ◽  
Augustine F.B. Cheng ◽  
...  
2015 ◽  
Vol 10 (3) ◽  
pp. 407-425 ◽  
Author(s):  
Shio-Shin Jean ◽  
Wen-Sen Lee ◽  
Carlos Lam ◽  
Chin-Wang Hsu ◽  
Ray-Jade Chen ◽  
...  

KYAMC Journal ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 171-175
Author(s):  
Tania Rahman ◽  
Momtaz Begum ◽  
Sharmeen Sultana ◽  
SM Shamsuzzaman

Background: In recent years, Extended-spectrum beta-lactamase (ESBL) producing microorganisms have complicated treatment of infections due to resistance of ESBL producing strains to a wide range of antimicrobials. Objective: Target of this study was to determine the prevalence of ESBL producing gramnegative bacteria in neonatal sepsis cases and to reveal the antimicrobial susceptibility pattern of those isolated ESBL producers. Materials and Methods: This cross sectional study was carried out in Dhaka Medical College Hospital (DMCH) over a period of 12 months from January to December in 2016. Following isolation and identification of gram-negative bacteria from blood samples of suspected septicemic neonates, antimicrobial susceptibility test was performed by Kirby Bauer disk-diffusion method and ESBL producers were detected by Double Disk Synergy (DDS) test. Results: Among 52 Gram-negative bacteria isolated from 106 blood samples, 34.61% ESBL producers were detected and Enterobacter spp. (45%) was predominant followed by Klebsiella pneumoniae (33.33%). None of the ESBL producers was resistant to colistin and tigecycline. All ESBL producing Acinetobacter baumannii, 77.78% and 66.67% of ESBL producing Enterobacter spp and Klebsiella spp. respectively showed resistance to meropenem. All ESBL producers were resistant to piperacillintazobactam. Conclusion: Appropriate measures should be taken to prevent the spread of ESBL producing strains by combining strategies for infection prevention, control and rational use of antibiotics. KYAMC Journal Vol. 11, No.-4, January 2021, Page 171-175


ANKEM Dergisi ◽  
2014 ◽  
Vol 28 (3) ◽  
pp. 79-85
Author(s):  
Esra Gultekin ◽  
M. Hamidullah Uyanik ◽  
Hayrunisa Hanci ◽  
Zeynep Erdil ◽  
Fatma Nesime Gelen ◽  
...  

2015 ◽  
Vol 7 ◽  
pp. e2015040 ◽  
Author(s):  
Silvano Esposito ◽  
Renato Gioia ◽  
Giuseppe De Simone ◽  
Silvana Noviello ◽  
Sebastiano Leone

Objectives: Surgical infections represent an increasingly important problem for the National Health System. In this study we retrospectively evaluated the bacterial epidemiology and antimicrobial susceptibility of the microorganisms concerned as well as the utilization of antibiotics in the General and Emergency Surgery wards of a large teaching hospital in southern Italy in the period 2011-2013.Methods: Data concerning bacterial isolates and antimicrobial susceptibility were retrieved from the Vitek II database. The pharmacy provided data about the consumption of antibiotics in the above reported wards. Chi-square or Fisher’s exact test were used to analyze categorical variables.Results: In all, 94 Gram-negative were isolated in 2011, 77 in 2012, and 125 in 2013, Escherichia coli, Acinetobacter baumannii and Pseudomonas aeruginosa always being the most frequently isolated microorganisms. In the same years, there were respectively 105, 93, and 165 Gram-positive isolated, Enterococcus faecalis, Staphylococcus epidermidis and Staphylococcus aureus being the most commonly found. No significant variation in the antibiotic susceptibility pattern was observed, either among Gram-negative or among Gram-positive pathogens; carbapenems (especially meropenem) consumption remained stable over time.Conclusions: Our results show no significant increase in antimicrobial resistance over the period in question, and a higher rate of both MRSA isolates and resistance to carbapenems in A. baumannii compared with other European data.


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