Functional Recovery of Hearing following AMPA-Induced Reversible Disruption of Hair Cell Afferent Synapses in the Avian Inner Ear

2001 ◽  
Vol 6 (2) ◽  
pp. 66-78 ◽  
Author(s):  
Diana Reng ◽  
Marcus Müller ◽  
Jean W.T. Smolders
Keyword(s):  
Hair Cell ◽  
Inner Ear ◽  
Functional Recovery ◽  
Avian Inner Ear

scholarly journals Identification of hair cell progenitors and intermitotic migration of their nuclei in the normal and regenerating avian inner ear

1994 ◽  
Vol 14 (1) ◽  
pp. 140-152 ◽  
Author(s):  
TT Tsue ◽  
DL Watling ◽  
P Weisleder ◽  
MD Coltrera ◽  
EW Rubel
Keyword(s):  
Hair Cell ◽  
Inner Ear ◽  
Avian Inner Ear

Hair cell replacement in the avian inner ear following two exposures to intense sound

1995 ◽  
Vol 24 (2) ◽  
pp. 111-116 ◽  
Author(s):  
Henry J. Adler ◽  
James C. Saunders
Keyword(s):  
Hair Cell ◽  
Inner Ear ◽  
Cell Replacement ◽  
Avian Inner Ear

scholarly journals Applying genomics to the avian inner ear: Development of subtractive cDNA resources for exploring sensory function and hair cell regeneration

Genomics ◽  
2006 ◽  
Vol 87 (6) ◽  
pp. 801-808 ◽  
Author(s):  
R. David Hawkins ◽  
Cynthia A. Helms ◽  
Julia B. Winston ◽  
Mark E. Warchol ◽  
Michael Lovett
Keyword(s):  
Hair Cell ◽  
Inner Ear ◽  
Sensory Function ◽  
Cell Regeneration ◽  
Hair Cell Regeneration ◽  
Ear Development ◽  
Inner Ear Development ◽  
Avian Inner Ear

Triggers of hair cell regeneration in the avian inner ear

1997 ◽  
Vol 24 (3) ◽  
pp. 221-225 ◽  
Author(s):  
Hideo Yamane ◽  
Takayuki Nakagawa ◽  
Hiroyoshi Iguchi ◽  
Shigetarou Shibata ◽  
Masahiro Takayama ◽  
...  
Keyword(s):  
Hair Cell ◽  
Inner Ear ◽  
Cell Regeneration ◽  
Hair Cell Regeneration ◽  
Avian Inner Ear

scholarly journals The Transcriptome of Utricle Hair Cell Regeneration in the Avian Inner Ear

2014 ◽  
Vol 34 (10) ◽  
pp. 3523-3535 ◽  
Author(s):  
Y.-C. Ku ◽  
N. A. Renaud ◽  
R. A. Veile ◽  
C. Helms ◽  
C. C. J. Voelker ◽  
...  
Keyword(s):  
Hair Cell ◽  
Inner Ear ◽  
Cell Regeneration ◽  
Hair Cell Regeneration ◽  
Avian Inner Ear

scholarly journals Identification of a 275-kD protein associated with the apical surfaces of sensory hair cells in the avian inner ear.

1990 ◽  
Vol 110 (4) ◽  
pp. 1055-1066 ◽  
Author(s):  
G P Richardson ◽  
S Bartolami ◽  
I J Russell
Keyword(s):  
Hair Cell ◽  
Inner Ear ◽  
Hair Cells ◽  
Proximal Region ◽  
Basilar Papilla ◽  
Relative Molecular Mass ◽  
Apical Surface ◽  
Sensory Hair ◽  
Sensory Hair Cells ◽  
Avian Inner Ear

Immunological techniques have been used to generate both polyclonal and monoclonal antibodies specific for the apical ends of sensory hair cells in the avian inner ear. The hair cell antigen recognized by these antibodies is soluble in nonionic detergent, behaves on sucrose gradients primarily as a 16S particle, and, after immunoprecipitation, migrates as a polypeptide with a relative molecular mass of 275 kD on 5% SDS gels under reducing conditions. The antigen can be detected with scanning immunoelectron microscopy on the apical surface of the cell and on the stereocilia bundle but not on the kinocilium. Double label studies indicate that the entire stereocilia bundle is stained in the lagena macula (a vestibular organ), whereas in the basilar papilla (an auditory organ) only the proximal region of the stereocilia bundle nearest to the apical surface is stained. The monoclonal anti-hair cell antibodies do not stain brain, tongue, lung, liver, heart, crop, gizzard, small intestine, skeletal muscle, feather, skin, or eye tissues but do specifically stain renal corpuscles in the kidney. Experiments using organotypic cultures of the embryonic lagena macula indicate that the antibodies cause a significant increase in the steady-state stiffness of the stereocilia bundle but do not inhibit mechanotransduction. The antibodies should provide a suitable marker and/or tool for the purification of the apical sensory membrane of the hair cell.

Two Modes of Auditory Hair Cell Loss following Acoustic Overstimulation in the Avian Inner Ear

ORL ◽  
1997 ◽  
Vol 59 (6) ◽  
pp. 303-310 ◽  
Author(s):  
Takayuki Nakagawa ◽  
Hideo Yamane ◽  
Shigetaro Shibata ◽  
Masahiro Takayama ◽  
Kishiko Sunami ◽  
...  
Keyword(s):  
Hair Cell ◽  
Inner Ear ◽  
Cell Loss ◽  
Hair Cell Loss ◽  
Acoustic Overstimulation ◽  
Avian Inner Ear
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