scholarly journals Synthetic, Biochemical, Antifertility and Antiinflammatory Aspects of Manganese and Iron Complexes

2002 ◽  
Vol 9 (1-2) ◽  
pp. 97-107 ◽  
Author(s):  
Ashu Chaudhary ◽  
Anita Phor ◽  
Sanjay Sharma ◽  
Anita Gajraj ◽  
R. V. Singh
Keyword(s):  
Elemental Analysis ◽  
Magnetic Moment ◽  
Phthalic Acid ◽  
Spectral Studies ◽  
Octahedral Structure ◽  
X Ray ◽  
Molar Ratios ◽  
Structural Aspects ◽  
Growth Inhibiting

Manganese(II) and iron(II) macrocyclic complexes of polyamide groups have been synthesized by the template codensation of diamines (2,6 diaminopyridine, 1,2 phenylenediamine and 1,3 phenylenediame) and triamine (diethylenetriamine) with phthalic acid in 1:2:2 molar ratios. On the basis of elemental analysis, IR, electronic, magnetic moment, Mössbauer, mass and X-ray spectral studies, octahedral structure has been assigned to [M(N4macn)Cl2] (M = Mn(II) and Fe(II), n = 1 to 4) complexes. The complexes have been screened in vitro against a number of fungi and bacteria to assess their growth inhibiting potential. An attempt has been made to correlate the structural aspects of the compounds with their antiinflammatory and antifertility activities.

scholarly journals Synthesis and Spectral Characterization of Mn(II) and Co(II) Complexes with Tetradentate Macrocyclic Ligand

2021 ◽  
Vol 33 (9) ◽  
pp. 2207-2211
Author(s):  
Usha Bansal ◽  
Samta Goyal ◽  
Swati Agrawal
Keyword(s):  
Metal Complexes ◽  
Infrared Spectra ◽  
Elemental Analysis ◽  
Magnetic Moment ◽  
Macrocyclic Ligand ◽  
Molar Conductance ◽  
Octahedral Geometry ◽  
Metal Salts ◽  
Spectral Studies

Manganese(II) and cobalt(II) complexes were synthesized with [N4] tetradentate macrocyclic ligand using different metal salts i.e. MnCl2, Mn(NO3)2, CoCl2 and Co(NCS)2. The ligand was prepared by condensation of glyoxal and carbahydrazide. All these were characterized by elemental analysis, molar conductance measurements, magnetic moment, IR, mass, electronic and EPR spectral studies. Elemental analysis indicates that the complexes have composition MLX2 where (X = Cl–, NO3 –,NCS–). All the complexes were found to be non-electrolytic in nature so can be formulated as [MLX2]. Infrared spectra of metal complexes suggest that the ligand behaves as tetradentate. On the basis of magnetic moment, electronic and EPR spectral data, all the metal complexes were found to be high spin with octahedral geometry.

scholarly journals Synthesis and spectroscopic characterization of some lanthanide(III) nitrate complexes of 3-[3-carboxyethyl-4,5- dimethylthiophene-2-yl)azo]pent-2,4-dione

2011 ◽  
Vol 76 (2) ◽  
pp. 249-261 ◽  
Author(s):  
Janardhanan Athira ◽  
Yesodharan Sindhu ◽  
Susamma Sujamol ◽  
Kochukittan Mohanan
Keyword(s):  
Elemental Analysis ◽  
Metal Ion ◽  
Spectroscopic Characterization ◽  
Molar Conductance ◽  
Spectral Studies ◽  
Structural Form ◽  
X Ray Diffraction ◽  
X Ray ◽  
Nitrate Complexes

3-[3-Carboxyethyl-4,5-dimethylthiophene-2-yl)azo]pent-2,4-dione was synthesized by coupling diazotized 2-amino-3-carboxyethyl- 4,5-dimethylthiophene with acetylacetone. Based on various spectral studies and elemental analysis, an intramolecularly hydrogen bonded azoenol structural form was assigned for the ligand. This ligand is versatile in forming a series of lanthanide(III) complexes viz, lanthanum(III), cerium(III), praseodymium(III), neodymium(III), samarium(III) and gadolinium(III), which were characterized through various spectral studies, elemental analysis, magnetic susceptibility measurements, molar conductance and thermal analysis. The spectral data revealed that the ligand acted as a neutral tridentate, coordinating to the metal ion through one of the azo nitrogen atoms, the ester carbonyl and the enolic oxygen of the acetylacetone moiety, without deprotonation. Molar conductance values adequately supported their non-electrolytic nature. The ligand and lanthanum(III) complexes were subjected to X-ray diffraction studies. In addition, the lanthanum(III) complex underwent a facile transesterification reaction on refluxing with methanol for a long period. The thermal behavior of the lanthanum(III) complex was also examined.

scholarly journals Structural studies on di-µ-thiocyanato(N,S)-bis(ligand)diisothiocyanato metal(II)bis(triphenylphosphine)mercury(II) and selenocyanate analogs

1979 ◽  
Vol 57 (4) ◽  
pp. 394-399 ◽  
Author(s):  
P. P. Singh ◽  
S. P. Yadav
Keyword(s):  
Elemental Analysis ◽  
Magnetic Moment ◽  
Molar Conductance ◽  
Mixed Ligand ◽  
Spectral Studies ◽  
Structural Studies ◽  
Mixed Metal

Binuclear mixed-metal mixed-ligand monomeric bridged complexes of the type (XCN)2(L)2M(NCX)2Hg(PPh3)2 (M = Co(II), Ni(II), Cu(II), Zn(II); L = pyridine, nicotinamide; PPh3 = triphenylphosphine; X = S, Se) have been synthesized and characterized by elemental analysis, molar conductance, magnetic moment, and infrared and electronic spectral studies. In all the complexes, the most likely structure involves pyridine or nicotinamide linked to M and PPh3 to Hg. Total softness calculations have also been made to extend support to the structure of the complexes.

scholarly journals Synthesis, Characterization, and Biological Activity ofN′-[(Z)-(3-Methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)(phenyl)methyl]benzohydrazide and Its Co(II), Ni(II), and Cu(II) Complexes

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Jonnie N. Asegbeloyin ◽  
Oguejiofo T. Ujam ◽  
Emmanuel C. Okafor ◽  
Ilknur Babahan ◽  
Esin Poyrazoglu Coban ◽  
...  
Keyword(s):  
Magnetic Measurements ◽  
Structure Study ◽  
Molar Conductance ◽  
Promyelocytic Leukemia ◽  
Leukemia Cells ◽  
Spectral Studies ◽  
X Ray Diffraction ◽  
X Ray ◽  
Gram Positive Bacteria

Reaction of 1-phenyl-3-methyl-4-benzoyl-pyrazol-5-one and benzoyl hydrazide in refluxing ethanol gaveN′-[(Z)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)(phenyl)methyl]benzohydrazide (HL1), which was characterized by NMR spectroscopy and single-crystal X-ray structure study. X-ray diffraction analyses of the crystals revealed a nonplanar molecule, existing in the keto-amine form, with intermolecular hydrogen bonding forming a seven-membered ring system. The reaction of HL1with Co(II), Ni(II), and Cu(II) halides gave the corresponding complexes, which were characterized by elemental analysis, molar conductance, magnetic measurements, and infrared and electronic spectral studies. The compounds were screened for theirin vitrocytotoxic activity against HL-60 human promyelocytic leukemia cells and antimicrobial activity against some bacteria and yeasts. Results showed that the compounds are potent against HL-60 cells with the IC50value ≤5 μM, while some of the compounds were active against few studied Gram-positive bacteria.

scholarly journals DNA Binding Test, X-Ray Crystal Structure, Spectral Studies, TG-DTA, and Electrochemistry of [CoX2(dmdphphen)] (Dmdphphen Is 2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline, X = Cl, and NCS) Complexes

2014 ◽  
Vol 2014 ◽  
pp. 1-7
Author(s):  
Mousa Al-Noaimi ◽  
Mohammed Suleiman ◽  
Hany W. Darwish ◽  
Ahmed H. Bakheit ◽  
Muneer Abdoh ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Cyclic Voltammetry ◽  
Elemental Analysis ◽  
Mixed Ligand ◽  
Spectral Studies ◽  
X Ray Diffraction ◽  
X Ray ◽  
Tetrahedral Environment ◽  
One Step ◽  
Ct Dna

Two new neutral mixed-ligand cobalt(II) complexes, [CoCl2(dmdphphen)]1and [Co(NCS)2(dmdphphen)]  2, where dmdphphen is 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline, were synthesized and characterized by an elemental analysis, UV-Vis, IR, TG/DTA, cyclic voltammetry CV, and single X-ray diffraction. Complex2crystallized as monoclinic with a space group P21/c. Co(II) ions are located in a distorted tetrahedral environment. TG/DTA result shows that these complexes are very stable and decomposed through one-step reaction. The two complexes exhibit a quasireversible one-electron response at −550 and 580 mV versus Cp2Fe/Cp2Fe+, which has been assigned to Co(I)/Co(II) and Co(II)/Co(III) couples. Absorption spectral studies reveal that such complexes exhibit hypochromicity during their interaction with CT-DNA.

scholarly journals Txicological Aspects of Newly Designed Macrocyclic Complexes of Iron(II)

2002 ◽  
Vol 8 (6) ◽  
pp. 315-321 ◽  
Author(s):  
Ashu Chaudhary ◽  
R. V. Singh
Keyword(s):  
Binding Sites ◽  
Brine Shrimp ◽  
Condensation Reaction ◽  
Octahedral Geometry ◽  
Macrocyclic Complexes ◽  
Spectral Studies ◽  
X Ray ◽  
Mass Spectral ◽  
Molar Ratios ◽  
Elemental Analyses

Brine shrimp lethality of a new series of 16 to 26-membered macrocycles of iron(II) containing tetraaza groups and prepared by the template condensation reaction of diacarboxylic acids (malonic, succinic, glutaric or adipic) with 2,6-diaminopyridine and diethylenetriamine in 1:2:2 molar ratios have been studied. Structures and bonding of the macrocyclic complexes have been proposed based on elemental analyses, IR, electronic, X-ray and mass spectral studies. An octahedral geometry for these complexes has been proposed as the binding sites are the nitrogen atoms of the macrocycles. The formation of the complexes as [Fe(Ln)Cl2] has been established on the basis of the chemical composition. The complexes have also been screened against several microbes.

scholarly journals Metal Complexation Studies of 1-(4-Carboxy-3-hydroxy-N-methyl phenyl- amino methyl) 2-methyl perimidine

2009 ◽  
Vol 6 (s1) ◽  
pp. S452-S458
Author(s):  
Umang N. Patel ◽  
Arun Singh
Keyword(s):  
Antimicrobial Activity ◽  
Transition Metal Complexes ◽  
Elemental Analysis ◽  
Magnetic Moment ◽  
Conductivity Measurement ◽  
Molar Conductivity ◽  
Spectral Studies ◽  
Aminosalicylic Acid ◽  
Complexation Studies ◽  
Methyl Phenyl

Aminomethylation of 2-methyl perimidine was carried out by treating 2-methyl perimidine with formaldehyde and 4-aminosalicylic acid. The resultant compound was designed as 1-(4-caroxy-3-hydroxy-N-methyl phenylamino methyl)2-methyl perimidine. The transition metal complexes of Cu2+, Co2+, Ni2+, Mn2+and Zn2+have been prepared and characterized by elemental analysis, spectral studies, magnetic moment determination, molar conductivity measurement and antimicrobial activity.

scholarly journals Molecular design and synthesis of new dithiocarbazate complexes; crystal structure, bioactivities and nano studies

RSC Advances ◽  
2018 ◽  
Vol 8 (73) ◽  
pp. 41795-41809 ◽  
Author(s):  
Zahra Yekke-ghasemi ◽  
Reza Takjoo ◽  
Mohammad Ramezani ◽  
Joel T. Mague
Keyword(s):  
Crystal Structure ◽  
Mass Spectrometry ◽  
Metal Complexes ◽  
Elemental Analysis ◽  
Molecular Design ◽  
X Ray ◽  
Design And Synthesis

New metal complexes are synthesized and characterized by elemental analysis, mass spectrometry, spectroscopic, TGA and X-ray techniques. The compounds were evaluated in anin vitrocytotoxicity. Interaction of the samples with HSA was investigated.

scholarly journals In vitro Interaction of Metronidazole and Mebendazole with Copper (II) and Chromium (III) in Aqueous Media

2011 ◽  
Vol 4 (1) ◽  
pp. 173 ◽  
Author(s):  
A. T. M. Z. Azam ◽  
F. Siraji ◽  
M. S. Amran ◽  
J. N. Islam ◽  
F. M. Amjad ◽  
...  
Keyword(s):  
Spectroscopic Method ◽  
Aqueous Media ◽  
Conductometric Titration ◽  
Spectral Studies ◽  
Stable Complex ◽  
Fixed Temperature ◽  
Molar Ratios ◽  
Spectrophotometric Methods ◽  
Ph Values

The interaction of metronidazole, an antiprotozoal agent and mebendazole, an important anthelmentic agent with Cu (II) and Cr(III) ions have been studied in aqueous systems at a fixed temperature of 37±0.5°C  and at different pH values. It has been found that metronidazole and mebendazole form stable 1:1 complexes with Cu(II), but a less stable complex with Cr(III) ion.  The studies were performed by electroanalytical and spectrophotometric methods. Spectral studies helped to detect initial complexation between the species. Conductometric titration indicated the nature of interaction and the stoichiometries of complexation. The conductometric study also indicated the formation of complexes of various molar ratios viz 1:2, 4:1, 3:1, 1:2, 1:3 and 1:4. etc. along with 1:1 complexes at various pH conditions. Similar types of complexation were observed by Job’s plots at various pH values. The Ardon’s spectroscopic method confirmed the 1:1 complexation and the values of stability constant were calculated using Ardon’s plot. Complexation at molar ratios 1:3 and 1:4 can not be ruled out. Keywords:  Metronidazole; Mebendazole; Cu(II); Cr(III); Ardon’s plot; Complexation. © 2012 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. doi: http://dx.doi.org/10.3329/jsr.v4i1.7599J. Sci. Res. 4 (1), 173-181 (2012)

scholarly journals Metal Complexation Studies of 1-(4-Carboxy-3-hydroxy-4-phenyl amino methyl) benzotriazole

2009 ◽  
Vol 6 (2) ◽  
pp. 475-480 ◽  
Author(s):  
P. K. Patel ◽  
P. D. Dpatel
Keyword(s):  
Transition Metal ◽  
Metal Complex ◽  
Elemental Analysis ◽  
Magnetic Moment ◽  
Transition Metal Complex ◽  
Conductivity Measurement ◽  
Molar Conductivity ◽  
Spectral Studies ◽  
Aminosalicylic Acid ◽  
Complexation Studies

Aminomethylation of benzotriazole was carried out by treating benzotrialzole with formaldehyde and 4-aminosalicylic acid. The resultant compound was designed as 1-(4-carboxy-3-hydroxy-4-phenyl amino methyl) benzotriazole. The transition metal complex of Cu2+, Co2+, Ni2+, Mn2+, and Zn2+, of 1-(4-carboxy-3-hydroxy-4-phenyl amino methyl) benzotriazole have been prepared. Elemental analysis, spectral studies, magnetic moment determination, molar conductivity measurement and microbial activity of 1-(4-carboxy-3-hydroxy-4-phenyl amino methyl) benzotriazole and its metal complexes were carried out.

Sign in / Sign up

Export Citation Format

Share Document