scholarly journals Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Saif Al-Zahid ◽  
Tanwen Wright ◽  
Philip Reece
Keyword(s):  
Case Report ◽  
Multidisciplinary Approach ◽  
The Body ◽  
Mycobacterium Kansasii ◽  
Mycobacterial Disease ◽  
Inflammatory Pseudotumour ◽  
First Case ◽  
Benign Tumours ◽  
High Index Of Suspicion ◽  
Work Up

Background. Inflammatory pseudotumours (IPT) are rare benign tumours characterised by spindle-shaped histiocyte proliferation often mimicking a soft tissue sarcoma. They can occur in different parts of the body and various aetiological factors have been proposed. To our knowledge this is the first case report of IPT of the larynx caused by mycobacterial disease. Case Report. We report a case of IPT of the larynx in an immunocompromised 81-year-old lady presenting with stridor and dysphagia with known disseminated Mycobacterium kansasii of the lungs. Conclusion. This case demonstrates both the clinical and histological difficulties in making the diagnosis of IPT. A high index of suspicion is needed, and the importance of a multidisciplinary approach in the work-up, diagnosis, and management is highlighted.

scholarly journals Pulmonary Fibrosis after Pegylated Liposomal Doxorubicin in Elderly Patient with Cutaneous Angiosarcoma

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Marco Mazzotta ◽  
Raffaele Giusti ◽  
Daniela Iacono ◽  
Salvatore Lauro ◽  
Paolo Marchetti
Keyword(s):  
Elderly Patient ◽  
Case Report ◽  
Pulmonary Fibrosis ◽  
Pulmonary Toxicity ◽  
Liposomal Doxorubicin ◽  
Pegylated Liposomal Doxorubicin ◽  
The Body ◽  
Rare Cancer ◽  
True Incidence ◽  
First Case

Introduction. Angiosarcoma is a rare cancer of the inner lining of blood vessels and can arise anywhere in the body, most commonly presenting as cutaneous disease in elderly patient, involving head and neck (H&N), especially the scalp. Pegylated liposomal doxorubicin (PLD) is one of the available treatments in patients with advanced or metastatic disease. Common toxicities are myelosuppression, palmar-plantar erythrodysesthesia, nausea, and stomatitis. Regarding PLD-related pulmonary fibrosis in an uncommon toxicity, there are few cases reported in literature. None of these occurred in angiosarcoma.Methods. This is a case report describing an elderly patient treated with PLD for advanced H&N cutaneous angiosarcoma who developed G5 pulmonary toxicity after the second PLD administration.Results. According to our data and patient clinical outcome, we believe that she passed away from fatal PLD-induced pulmonary fibrosis. This is the first case of fatal interstitial pneumonitis in a 77-year-old woman treated with PLD for angiosarcoma. The case has been reported for its rarity.Conclusions. Pathophysiology of this phenomenon is still unclear and more studies are necessary to understand the true incidence of pulmonary toxicities in patients in treatments with PLD and its mechanism.

scholarly journals Anti-NMDA Encephalitis: A Rare Encephalitis in a Child- A Case Report

2020 ◽  
Vol 19 (2) ◽  
pp. 108-111
Author(s):  
Saurav Khetan ◽  
Nikhil Agrawal ◽  
Prakash Rajoli
Keyword(s):  
Case Report ◽  
Japanese Encephalitis ◽  
Viral Encephalitis ◽  
Psychiatric Symptoms ◽  
Autoimmune Encephalitis ◽  
High Index ◽  
First Case ◽  
High Index Of Suspicion

Anti-NMDA encephalitis is second commonest cause of autoimmune encephalitis among children; however, it is hardly diagnosed and often not considered as one of the differentials when a child presents with encephalitis-related symptoms. In children, it presents mostly with seizures or psychiatric symptoms without prodrome. Here we present a six years old girl who presented with seizures and inappropriate behaviour. We investigated her in the line of viral encephalitis such as Japanese Encephalitis, which is very common in our region. However, results were not suggestive of Japanese Encephalitis and further investigations subsequently lead to diagnosis of anti- NMDA encephalitis. This is probably one of the first case report of this disease in our country. We want to highlight the significance of high index of suspicion for looking out for an organic cause in any child who presents with psychiatric symptoms, along with seizures.

scholarly journals Solitary Fibrous Tumor of the Postcricoid Region: A Case Report and Literature Review

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Brian Cervenka ◽  
Brenda Villegas ◽  
Uttam Sinha
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Solitary Fibrous Tumor ◽  
Management Strategies ◽  
The Body ◽  
Surgical Approaches ◽  
Current Management ◽  
First Case ◽  
Mesenchymal Neoplasm ◽  
Fibrous Tumor

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm that can present essentially anywhere in the body. Presentations in the hypopharynx are extremely rare with only two previous cases reported. We report the first case of postcricoid SFT occurring in a 58-year-old male requiring a microsuspension laryngoscopy excision following an unsuccessful transoral robotic attempt. The excision was uneventful, and the patient is currently without recurrence. Current management strategies of the hypopharyngeal SFT, the unique differential diagnosis, and challenges in surgical approaches in the postcricoid region are discussed.

scholarly journals Tuberous sclerosis with cardiac rhabdomyoma: a case report

2017 ◽  
Vol 4 (2) ◽  
pp. 666
Author(s):  
Sunita Arora ◽  
Harnoorjit Kaur Brar ◽  
Prabhjot Kaur Dhillon
Keyword(s):  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Genetic Disorder ◽  
Clinical Manifestations ◽  
Female Child ◽  
The Body ◽  
Cardiac Rhabdomyoma ◽  
Cardiac Evaluation ◽  
Benign Tumours ◽  
High Index Of Suspicion

Tuberous sclerosis or tuberous sclerosis complex (TSC) is a genetic disorder, caused by mutations on either of two genes TSC1 and TSC2. Clinical manifestations are caused by growth of benign tumours in different parts of the body. Ten months old female child with four major criteria of tuberous sclerosis complex and asymptomatic cardiac rhabdomyoma is presented. A case of TSC warrants cardiac evaluation for the presence of cardiac rhabdomyoma and if a cardiac rhabdomyoma is detected on antenatal ultrasound or postnatal echocardiography, one should have high index of suspicion for the diagnosis of TSC. Continued research on this disease has unfolded many realities regarding its etiology as well as treatment.

Primary Epithelioid Rhabdomyosarcoma of the Liver: Case Report of an Unusual Histological Variant

2021 ◽  
pp. 106689692110498
Author(s):  
Harumi Nakamura ◽  
Yuki Koyanagi ◽  
Masanori Kitamura ◽  
Yoji Kukita
Keyword(s):  
Case Report ◽  
Striated Muscle ◽  
Fusion Gene ◽  
Liver Lesion ◽  
The Body ◽  
Base Substitution ◽  
Entire Body ◽  
Positive Ratio ◽  
First Case ◽  
Histological Variant

Rhabdomyosarcoma (RMS) is a soft tissue tumor with striated muscle cell differentiation. It mostly occurs in children. While it can affect any part of the body, it commonly involves the urogenital organs, head and neck including the parameninges and orbit, and limbs. We describe an adult case of primary epithelioid RMS of the liver. A 71-year-old man presented with a 5.6 cm liver mass. Tumor histology revealed diffuse proliferation of small epithelioid cells and focal spindle cells. The tumor cells were immunohistochemically positive for myogenin (positive ratio 30%), desmin, Myo D1, and CD56. The tumor weakly expressed MDM2 and did not express CDK4. This suggested that dedifferentiated liposarcoma with a rhabdomyosarcomatous component was unlikely. There was no fusion gene of PAX3-FKHR or PAX7- FKHR to indicate alveolar RMS by RT-PCR. Subsequently, RNA Pan-Cancer Targeted sequencing was performed for 1385 genes revealed a single base substitution (c.742C>T) in TP53 that changes an amino acid (p.Arg248Trp). No fusion gene was found. No other primary RMS lesions were detected aside from the liver lesion. The tumor was diagnosed as a primary epithelioid RMS of the liver. His RMS already metastasized to the lymph nodes of the entire body. The patient declined further therapy and died one year later. This was the first case report of a primary epithelioid RMS of the liver.

scholarly journals A Case Report of Coccidioidomycosis in the Renal Parenchyma of Unusual Severity

2021 ◽  
Vol 9 ◽  
pp. 232470962199533
Author(s):  
Jeffrey A. Coleman ◽  
Valerie F. Civelli ◽  
Rupam Sharma ◽  
Arash Heidari ◽  
Royce H. Johnson
Keyword(s):  
United States ◽  
Case Report ◽  
South America ◽  
The United States ◽  
The Body ◽  
Renal Parenchyma ◽  
Genitourinary System ◽  
First Case ◽  
Disseminated Disease ◽  
Hispanic Male

Coccidioidomycosis (CM) is an endemic fungal infection that is found in the Southwestern United States and adjacent areas of Mexico as well as Central and South America. In the United States, 150 000 to 300 000 infections occur annually. The majority are asymptomatic. Of the symptomatic cases, the majority are primary pneumonic disease that varies from mild to very severe. A minority of persons develop disseminated disease (extrapulmonary disease). These typically manifest as meningitis, osteomyelitis, synovitis, and integumentary. CM has been described in virtually every part of the body, including the genitourinary system. Disseminated CM to the genitourinary tract is well known to occur but is rarely documented. It is believed this is the first case to report disseminated CM to the renal parenchyma. Diagnosis and treatment are described in a 56-year-old Hispanic male.

scholarly journals A Giant Egg-like symptomatic Loose Body in the Peritoneal Cavity: A Case Report

1970 ◽  
Vol 29 (6) ◽  
Author(s):  
Berhanetsehay Teklewold ◽  
Anteneh Kehaliw ◽  
Melat Teka ◽  
Bereket Berhane
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Incidental Finding ◽  
Loose Body ◽  
Loose Bodies ◽  
Diagnostic Challenge ◽  
First Case ◽  
Appendices Epiploicae ◽  
The One ◽  
High Index Of Suspicion

Background: Peritoneal loose bodies are rare lesions that are usually found as an incidental finding during abdominal surgery. Large loose bodies, measuring more than 5 cm, are rare and only a few cases are reported in the literature. Peritoneal loose bodies are usually infarcted appendices epiploicae, which become detached and appear as a peritoneal loose body in the abdominal cavity.Case Presentation: We report here the first case, in the local Ethiopian context, of a giant “egg-like” loose peritoneal body measuring 7 × 6 cm found in a 50-year-old man who presented with a cramping abdominal pain and features of abdominal obstruction. The current hypothesis as regards these bodies and the diagnostic challenges is discussed.Conclusion: Small peritoneal loose bodies are common but giant and symptomatic ones’, like the one discussed here, are very rare and a diagnostic challenge. And, in the context of intestinal obstruction, a high index of suspicion is needed in order to diagnose them.

scholarly journals Lymphoepithelial carcinoma in the body of the tongue: The first case report

2020 ◽  
Author(s):  
Ono Sawako ◽  
Hidenori Marunaka ◽  
Hiroyuki Yanai ◽  
Hotaka Kawai ◽  
Kiyofumi Takabatake ◽  
...  
Keyword(s):  
Case Report ◽  
Undifferentiated Carcinoma ◽  
The Body ◽  
Epstein Barr Virus Infection ◽  
Lymphoepithelial Carcinoma ◽  
Barr Virus ◽  
First Case ◽  
Common Location ◽  
Epstein Barr ◽  
Barr Virus Infection

Abstract Background Lymphoepithelial carcinoma (LEC) of the tongue is a rare subtype of squamous cell carcinoma. Histologically, it is an undifferentiated carcinoma with rich lymphocyte and plasma cell infiltration. The most common location for LEC in the head and neck is the salivary glands, and LEC of the oral cavity is extremely rare1. Conclusions The first case report of LEC in the body of the tongue is presented. In addition, a review of the literature was performed, and the relationship between LEC and Epstein-Barr virus infection was considered.

scholarly journals Laparoscopic management of renal and hepatic hydatidosis in a child: a case report and review of literature

2017 ◽  
Vol 4 (5) ◽  
pp. 1793
Author(s):  
Rajashekhar T. Patil ◽  
Sandesh V. Parelkar ◽  
Beejal Sanghvi
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Laparoscopic Surgery ◽  
Renal Involvement ◽  
The Body ◽  
Cystic Disease ◽  
Review Of Literature ◽  
Intermediate Hosts ◽  
Hepatic Hydatidosis ◽  
First Case

Hydatidosis is an endemic disease caused by Echinococcus granulosus. Humans are accidental intermediate hosts. In children, it affects the lung in 64% of cases and the liver in 28%. Renal involvement is uncommon (2-4%). We operated 7 years old girl with renal and hepatic hydatidosis laparoscopically. Hydatid cyst should be kept as one of differential diagnosis while managing cystic disease of any organ in the body. To the best of our knowledge this is the first case of renal hydatidosis with hepatic hydatidosis that has been managed laparoscopically. Laparoscopic surgery is safe and efficacious in managing multiorgan hydatid disease in children.

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