First case report of Epstein–Barr virus‐positive inflammatory pseudotumour‐like follicular dendritic cell sarcoma in Australia

2020 ◽  
Author(s):  
Thomas Rogerson ◽  
Markus Trochsler ◽  
John Miliauskas ◽  
Guy Maddern
Keyword(s):  
Case Report ◽  
Epstein Barr Virus ◽  
Follicular Dendritic Cell ◽  
Follicular Dendritic Cell Sarcoma ◽  
Inflammatory Pseudotumour ◽  
Cell Sarcoma ◽  
Barr Virus ◽  
Dendritic Cell Sarcoma ◽  
First Case ◽  
Epstein Barr

The Image Presentation of Inflammatory Follicular Dendritic Cell Sarcoma Mimic Primary Cholangiocarcinoma in Epstein-Barr Virus Prevalent Country: A Case Report and Literature Review

2021 ◽  
Author(s):  
WuPo Chao ◽  
Yi-Chan Chen ◽  
Cheng-Han Yang ◽  
Rueyshyang Soong
Keyword(s):  
Case Report ◽  
Dendritic Cell ◽  
Liver Tumor ◽  
Epstein Barr Virus ◽  
Follicular Dendritic Cell ◽  
Follicular Dendritic Cell Sarcoma ◽  
Cell Sarcoma ◽  
Barr Virus ◽  
Dendritic Cell Sarcoma ◽  
Epstein Barr

Abstract Background: Follicular dendritic cell sarcoma (FDCS) is a very rare malignant soft tissue tumor. About half of the cases occurred in lymph node, mostly around neck. The uncommon inflammatory variant of FDCS is an Epstein-Barr virus (EBV)-associated neoplasm. It was first introduced as Inflammatory pseudotumor-like FDC in 2001. Few cases had been found in liver and spleen as primary tumor. It mimicked the presentation of cholangiocarcinoma in this case and few had been reported as primary liver tumor yet. Case report: We represent a 53-year-old man who was referred to our department with a liver tumor. The tumor was accidently found during health exam at lateral segment, which was suspected to be cholangiocarcinoma on Magnetic Resonance Imaging(MRI). The liver segment was complete resected via laparoscopic hepatectomy. The tumor turned out to be inflammatory FDCS. The tumor specimen was margin free. No recurrence was detected at a 12-month follow-upClinical Discussion: Inflammatory FDCS often found in liver and spleen. Taiwan was EBV high-prevalence country, but the occurrence seemed not related. Current management as FDCS, with radiation therapy and chemotherapy if total resection was not feasible.Conclusion: Inflammatory FDCS is a rare malignant tumor in abdomen. Complete resection represents favorable outcome.

Hepatic Follicular Dendritic Cell Sarcoma Without Epstein-Barr Virus Expression

2005 ◽  
Vol 129 (11) ◽  
pp. 1480-1483 ◽  
Author(s):  
Ulises Torres ◽  
William G. Hawkins ◽  
Cristina R. Antonescu ◽  
Ronald P. DeMatteo
Keyword(s):  
Dendritic Cell ◽  
Epstein Barr Virus ◽  
Follicular Dendritic Cell ◽  
Follicular Dendritic Cell Sarcoma ◽  
Cell Sarcoma ◽  
Barr Virus ◽  
Dendritic Cell Sarcoma ◽  
Spindle Cell Proliferation ◽  
Follicular Dendritic ◽  
Epstein Barr

Abstract Follicular dendritic cell sarcoma of the liver is an uncommon pathologic entity, and only 5 cases have been reported previously. Herein, we report the first case, to our knowledge, of hepatic follicular dendritic cell sarcoma without evidence of Epstein-Barr virus infection. The patient is an elderly man who was found to have an incidental liver mass and then developed weight loss and fever. The diagnosis was based on the typical morphologic appearance of spindle cell proliferation associated with a brisk lymphoplasmacytic infiltrate and strong immunoreactivity to CD21 and CD35. Based on our experience and a review of the published reports, we summarize the clinical and pathologic features of hepatic follicular dendritic cell sarcoma and its surgical management.

scholarly journals Follicular dendritic cell sarcoma presenting as a thyroid mass: an unusual case report and literature review

2020 ◽  
Vol 48 (6) ◽  
pp. 030006052092043
Author(s):  
Ting Zhang ◽  
Liang He ◽  
Zhihong Wang ◽  
Wenwu Dong ◽  
Wei Sun ◽  
...  
Keyword(s):  
Case Report ◽  
Dendritic Cell ◽  
Radical Neck Dissection ◽  
Follicular Dendritic Cell ◽  
Follicular Dendritic Cell Sarcoma ◽  
Cell Sarcoma ◽  
Dendritic Cell Sarcoma ◽  
First Case ◽  
Follicular Dendritic ◽  
Rare Malignancy

Thyroid follicular dendritic cell sarcoma (FDCS) is an extremely rare malignancy that originates from follicular dendritic cells of the germinal centers and is characterized by the neoplastic proliferation of spindled to ovoid cells. As there have been only five cases reported in the literature until now, the diagnostic and therapeutic information available to clinicians regarding thyroid FDCS is fairly limited. To our knowledge, this is the first case report of thyroid FDCS without a history of Hashimoto’s thyroiditis. A 48-year-old woman was found to have a slow-growing mass in the left thyroid. After total thyroidectomy and left modified radical neck dissection, the specimen demonstrated morphologic and immunohistochemical features of FDCS. The patient had a favorable prognosis with no evidence of disease 11 months after tumor excision.

scholarly journals Hepatic inflammatory pseudotumor-like follicular dendritic cell tumor: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Ana Daniela Pascariu ◽  
Andreea Ioana Neagu ◽  
Andrei Valentin Neagu ◽  
Alexandru Băjenaru ◽  
Cezar Iulian Bețianu
Keyword(s):  
Dendritic Cell ◽  
Inflammatory Pseudotumor ◽  
Follicular Dendritic Cell ◽  
Follicular Dendritic Cell Sarcoma ◽  
Cell Sarcoma ◽  
Barr Virus ◽  
Dendritic Cell Sarcoma ◽  
Follicular Dendritic ◽  
Epstein Barr ◽  
Hepatic Inflammatory Pseudotumor

Abstract Background Inflammatory pseudotumor-like follicular dendritic cell sarcoma is a rare histological variant of follicular dendritic cell sarcoma involving typically the spleen and the liver, often linked to the presence of Epstein–Barr virus infection. Definite diagnosis of this type of sarcoma is difficult to make owing to nonspecific clinical and imaging findings and is based on histopathological features. Inflammatory pseudotumor-like follicular dendritic cell sarcoma is described as a low-aggressivity tumor with a favorable prognosis. Case presentation We report the case of a 34-year-old Caucasian woman, Epstein–Barr virus positive, diagnosed with hepatic inflammatory pseudotumor-like follicular dendritic cell sarcoma and surgically treated in November 2014, who developed 6 years later a recurrence for which she underwent once again surgical treatment. As far as we know, fewer than 30 reports of inflammatory pseudotumor-like follicular dendritic cell liver tumors have been reported in the English literature. Conclusions Although it is an uncommon tumor, inflammatory pseudotumor-like sarcoma is a diagnostic worth being taken in consideration, and surveillance is recommended owing to the possibility of recurrence.

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