scholarly journals Maxillary Sinus Kaposi Sarcoma: Case Report in an HIV-Negative Patient with Thymoma

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Bernardo Carvalho Araújo ◽  
Sara Viana Baptista ◽  
Luís Mascarenhas ◽  
Ezequiel Barros

Introduction. Kaposi sarcoma is an angioproliferative disorder that requires infection with human herpesvirus 8 (HHV-8) for its development. The majority of cases are associated with HIV infection or other immunocompromising conditions. Thymomas are occasionally associated to cytopenia, which may alter the patients’ immune responses. Methods. Case report using clinical records. Results. Case report of a 46-year-old male patient diagnosed with thymoma and myasthenia gravis. The patient was referred to an otolaryngology consultation with complaints of facial pain in the right malar region, interpreted as an acute sinusitis. Following examination, an expansive maxillary sinus mass was found, and endoscopic surgery was undertaken. After careful investigation, it was diagnosed as a Kaposi sarcoma. Conclusions. It is thought to be the first described case of a maxillary sinus Kaposi sarcoma in an HIV-negative patient. Thus, this entity has to be considered in the differential diagnosis of sinus masses, even in non-HIV patients.

2020 ◽  
Vol 13 (11) ◽  
pp. e237420
Author(s):  
Bernard Ho ◽  
Giulia Rinaldi ◽  
Imran Khan ◽  
Susanna Szakacs

A 36-year-old immunocompetent man who have sex with men first presented to the plastics team with an ulcerating lesion on his left first toe. The lesion was suggestive of pyogenic granuloma (PG) clinically and histologically. Two years later, the same patient presented to the dermatology clinic with a new erythematous lesion with intermittent bleeding on the left second toe. Clinically, this lesion was suggestive of another PG. However, the histology of the skin curettage revealed part of a PG merging with an atypical spindle cell proliferation with characteristic ‘sieve-like’ appearance in keeping with Kaposi sarcoma. This was confirmed with human herpesvirus-8 immunohistochemistry staining. PG-like Kaposi sarcoma is an uncommon variant of Kaposi sarcoma. Often not considered clinically or histologically, a deep skin biopsy is essential to establish the right diagnosis. Our case highlights the need to consider Kaposi sarcoma as a differential diagnosis in all patients, including HIV-negative individuals, presenting with PG-like lesions.


2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Zeliha Esin Celik ◽  
Murat Celik ◽  
Erdem Sen ◽  
Hakan Cebeci ◽  
Ozlem Ata ◽  
...  

Kaposi sarcoma (KS), a vascular tumor caused by infection with human herpesvirus 8 (HHV8), is a systemic disease that can present with cutaneous lesions with or without visceral involvement. Very few cases of KS, most of which were associated with AIDS, have been reported in the adrenal gland. Anaplastic transformation of KS is a rare clinical presentation known as an aggressive disease with local recurrence and metastatic potential. We report here a 47-year-old HIV negative male presented with extra-adrenal symptoms and had an incidentally detected anaplastic adrenal KS exhibited aggressive clinical course. To the best of our knowledge, this is the first case of anaplastic primary adrenal KS without mucocutaneous involvement but subsequently developed other side adrenal metastases in an HIV negative patient.


2019 ◽  
Vol 57 (1) ◽  
pp. 46-49 ◽  
Author(s):  
Erol Keles ◽  
◽  
Cihan Turker ◽  
Gokhan Artas ◽  
Turgut Karlidag ◽  
...  

2019 ◽  
Vol 7 (6) ◽  
pp. 1021-1024 ◽  
Author(s):  
Tiziana Peduto ◽  
Francesco Cillo ◽  
Paola Nappa ◽  
Mario Delfino ◽  
Gabriella Fabbrocini ◽  
...  

BACKGROUND: Kaposi's sarcoma (KS) is a tumour of endothelial, blood and lymphatic cells, caused by an infection with human herpesvirus-8 (HHV-8). The skin lesions of KS, especially of the classical or Mediterranean variant (CKS), are represented by red-purple macules, plaques and nodules, localised mainly on the extremities. CASE REPORT: This case series intend to describe multifocal atypical kaposian manifestations in two HIV negative subjects, affected by CKS, treated with successful chemotherapy. CONCLUSIONS: Although atypical manifestations are extremely rare events, we suggest an accurate, objective examination because a prompt diagnosis can lead to a vital intervention in the patient's health and sometimes to the identification of the disease itself.


Author(s):  
ifa Etesami ◽  
Yasamin Kalantari ◽  
Alireza Ghanadan ◽  
Azadeh Rezayat

Kaposi sarcoma (KS) is an angioproliferative disorder. While KS of the head and neck is common in HIV-positives, it’s rare in HIV-negatives. Our case and the past 24 reported cases of ear KS reviewed here, highlight the importance of considering KS in the differential diagnosis of ear lesions in HIV-negatives.


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