scholarly journals Chondrosarcomatous Differentiation in a Large Malignant Melanoma of the Scalp

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Colin S. Alderson ◽  
Helen E. Douglas ◽  
Rebecca Rollett ◽  
Bipin Mathew ◽  
Paolo Matteucci
Keyword(s):  
Malignant Melanoma ◽  
Female Patient ◽  
Delayed Diagnosis ◽  
Primary Resection ◽  
Metastatic Spread ◽  
Patient Treatment ◽  
Lentigo Maligna ◽  
Rare Phenomenon ◽  
Divergent Differentiation ◽  
Lentigo Maligna Melanoma

Background. Divergent differentiation in malignant melanoma is a rare phenomenon, which can lead to delayed diagnosis or misdiagnosis, impacting upon patient treatment and outcome, as well as the understanding of tumour behaviour. Case. We present the case of a large long-standing tumour on the scalp of a 72-year-old female patient, which when excised and examined histologically was revealed to be a nodular malignant melanoma displaying chondrosarcomatous differentiation. Foci suggestive of lentigo maligna were also present. Rapid metastatic spread of the tumour was observed shortly after the primary resection. Discussion. To our knowledge, this is the first reported case in the literature of chondrosarcomatous differentiation in a lentigo maligna melanoma. The clinical and histopathological details and images of this case are presented alongside a discussion regarding such tumours and patterns of similar tumour behaviour.

scholarly journals Malignant Melanoma Metastasis to the Appendix as the First Presentation of Lentigo Maligna Melanoma

2021 ◽  
Vol 24 (4) ◽  
pp. 330-332
Author(s):  
Shokouh Taghipour Zahir ◽  
Koorosh Rahmani ◽  
Seyed Abolfazl Hosseini
Keyword(s):  
Malignant Melanoma ◽  
Melanoma Metastasis ◽  
Lentigo Maligna ◽  
Lentigo Maligna Melanoma

Lentigo Maligna Melanoma

1978 ◽  
Vol 86 (5) ◽  
pp. ORL-743-ORL-746 ◽  
Author(s):  
Fred J. Stucker
Keyword(s):  
Elderly Patient ◽  
Malignant Melanoma ◽  
Good Prognosis ◽  
Premalignant Lesion ◽  
Diagnosis And Treatment ◽  
Lentigo Maligna ◽  
Clinical Pattern ◽  
Lentigo Maligna Melanoma ◽  
Proper Diagnosis ◽  
Slow Growing

Lentigo maligna melanoma is a malignant melanoma with a recognizable clinical pattern. It is a slow-growing, pigmented tumor evolving from a premalignant lesion on the exposed cutaneous surface of an elderly patient. Histologically, it is marked by pleomorphism of melanocytes with evidence of invasion. A case is presented demonstrating the features of this malignant melanoma with an exceptionally good prognosis. The importance of the clinical and histologic correlation is emphasized to ensure proper diagnosis and treatment.

Pagetoid malignant melanoma and lentigo maligna melanoma of toe

1978 ◽  
Vol 262 (3) ◽  
pp. 275-283 ◽  
Author(s):  
Takafumi Morishima ◽  
Toyonaga Ishikawa ◽  
Mikio Endo ◽  
Yoshiaki Tsujiguchi
Keyword(s):  
Malignant Melanoma ◽  
Lentigo Maligna ◽  
Lentigo Maligna Melanoma

scholarly journals Very Rare Amelanotic Lentigo Maligna Melanoma with Skull Roof Invasion

2017 ◽  
Vol 5 (4) ◽  
pp. 458-461 ◽  
Author(s):  
Uwe Wollina ◽  
Gesina Hansel ◽  
Nadine Schmidt ◽  
Jacqueline Schönlebe ◽  
Thomas Kittner ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Three Dimensional ◽  
Surgical Excision ◽  
Lentigo Maligna ◽  
Skull Roof ◽  
Complete Surgical Excision ◽  
Lentigo Maligna Melanoma ◽  
First Relapse ◽  
One Year ◽  
Serial Excision

BACKGROUND: Lentigo malignant melanoma is a melanoma subtype of chronic sun-damaged skin in elderly Caucasians. Amelanotic variants of lentigo malignant are extremely rare.CASE PRESENTATION: This is a case report of an 80-year-old male patient who presented with a non-pigmented exophytic tumour of his bald head. After complete surgical excision under the suspicion of squamous cell carcinoma, three-dimensional histologic examination confirmed an amelanotic lentigo malignant melanoma with a tumour thickness of 1.76 mm, resected R0. Five years later he developed the first relapse, the other year a satellite metastasis was surgically removed. One year later, this patient had developed a large relapsing lentigo malignant melanoma with skull roof invasion. There was no evidence of distant metastatic spread. Amelanotic lentigo malignant melanoma is a very rare tumour.CONCLUSIONS: Serial excision or slow Mohs and Mohs micrographic surgery are the treatments of choice especially in the head and neck area. These tumours may be locally very aggressive as it is shown by skull invasion in the present case.

Refractory Ascites as the Only Presenting Symptom of Chronic Calcified Constrictive Pericarditis: A Diagnostic Challenge

2014 ◽  
Vol 17 (1) ◽  
pp. 42
Author(s):  
Shi-Min Yuan
Keyword(s):  
Computed Tomography ◽  
Liver Cirrhosis ◽  
Female Patient ◽  
Constrictive Pericarditis ◽  
Delayed Diagnosis ◽  
Young Female ◽  
Refractory Ascites ◽  
Diagnostic Challenge ◽  
Massive Ascites ◽  
History Of

Extracardiac manifestations of constrictive pericarditis, such as massive ascites and liver cirrhosis, often cover the true situation and lead to a delayed diagnosis. A young female patient was referred to this hospital due to a 4-year history of refractory ascites as the only presenting symptom. A diagnosis of chronic calcified constrictive pericarditis was eventually established based on echocardiography, ultrasonography, and computed tomography. Cardiac catheterization was not performed. Pericardiectomy led to relief of her ascites. Refractory ascites warrants thorough investigation for constrictive pericarditis.

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