scholarly journals Acupuncture for Functional Dyspepsia: A Single Blinded, Randomized, Controlled Trial

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Yulian Jin ◽  
Qing Zhao ◽  
Kehua Zhou ◽  
Xianghong Jing ◽  
Xiaochun Yu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Treatment Group ◽  
Functional Dyspepsia ◽  
Mental Status ◽  
Serum Gastrin ◽  
Slow Waves ◽  
Control Group ◽  
Gastric Slow Waves ◽  
Dyspeptic Symptoms

In order to investigate the therapeutic potential of acupuncture on patients with functional dyspepsia (FD), patients were randomized to receive acupuncture at classic acupoints with manipulations (treatment group) versus acupuncture at nonacupoints without manipulation (control group) once every other day, three times a week, for one month and were followed up for three months. The primary outcomes included dyspeptic symptoms, quality of life, and mental status. The secondary outcomes included the fasting serum gastrin concentration, and frequency and propagation velocity of gastric slow waves. Sixty patients with FD were included, among whom, four dropped out. After one month's treatment, patients with FD showed significant improvements in primary (in both groups) and secondary (in the eight patients of the treatment group) outcomes as compared with baseline (P=0.0078to <0.0001); treatment group has better outcomes in all primary outcome measures (P<0.0001except for SDS (P=0.0005)). Improvements on dyspeptic symptoms persist during follow-up (better in the treatment group). Acupuncture with manual manipulation had better effects on improving dyspeptic symptoms, mental status, and quality of life in patients with FD. These effects may be related to the increased frequency and propagation speed of gastric slow waves and serum gastrin secretion.

scholarly journals The Effects ofBanha-sasim-tangon Dyspeptic Symptoms and Gastric Motility in Cases of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled, and Two-Center Trial

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Jae-Woo Park ◽  
Seok-Jae Ko ◽  
Gajin Han ◽  
Inkwon Yeo ◽  
Bongha Ryu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Functional Dyspepsia ◽  
Gastric Motility ◽  
Slow Waves ◽  
Double Blind ◽  
Early Satiety ◽  
Gastric Slow Waves ◽  
Quality Of Life Scale ◽  
Dyspeptic Symptoms

Introduction. Functional dyspepsia (FD) is highly prevalent, and no standard treatments exist for this condition. Herbal prescriptions are widely used to treat FD. In traditional Korean medicine,Banha-sasim-tang(BST) is a famous herbal prescription for dyspepsia. This study aimed to evaluate the efficacy of BST and to examine the relationship between gastric slow waves and dyspeptic symptoms.Materials and Methods. In total, 100 FD patients were recruited; BST or placebo was administered for 6 weeks. The gastrointestinal symptom scale, FD-related quality of life scale, and frequency or power variables regarding gastric slow waves were measured at 0, 6, and 14 weeks.Results. There were no significant differences in the overall dyspeptic symptoms or quality of life between the BST and placebo groups. However, early satiety was significantly improved in the BST group (P=0.009, at 6 weeks by intention-to-treat analysis). Abnormal gastric dysrhythmias and power ratios were also significantly improved by BST.Conclusion. BST had no significant effects on FD. However, early satiety appeared to improve after BST administration. Electrogastrography may be a useful technique for assessing changes in gastric motility dysfunction after interventions for FD. Further investigation focused on specific symptoms or subtypes of FD is required.

scholarly journals Impact and cost-effectiveness evaluation of a community-based rehabilitation intervention on quality of life among Chinese adults with hearing loss: study protocol for a randomized controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Xin Ye ◽  
Dawei Zhu ◽  
Siyuan Chen ◽  
Xuefeng Shi ◽  
Rui Gong ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hearing Loss ◽  
Cost Effectiveness ◽  
Treatment Group ◽  
Hearing Aids ◽  
Control Group ◽  
Chinese Adults ◽  
Community Based ◽  
The Impact

Abstract Background Hearing loss is quite prevalent and can be related to people’s quality of life. To our knowledge, there are limited studies assessing the efficacy of hearing interventions on quality of life in adults. Therefore, we aim to conduct a randomized controlled trial (RCT) to determine the impact and cost-effectiveness of community-based hearing rehabilitation on quality of life among Chinese adults with hearing loss. Methods/design In this two-arm feasibility study, participants aged 16 and above with some degree of hearing loss (n = 464) will be recruited from Linyi City, Shandong Province. They are randomly assigned to the treatment group or the control group. Those in the treatment group are prescribed with hearing aids, while those in the control group receive no intervention. Reinstruction in use of devices is provided for the treatment group during booster visits held 12 months post-randomization or unscheduled interim visits when necessary. Data are collected at baseline and the follow-up 20 months later. The primary outcome is changes in quality of life over a 20-month study period. Secondary outcomes include sub-dimensions in quality of life, physical functioning, chronic diseases, cognitive function, depression, social support, hospitalizations, falls, and healthcare costs. Finally, we will evaluate whether hearing aids intervention is cost-effective to apply in a large scale. Discussion The trial is designed to evaluate the impact and cost-effectiveness of a community-based rehabilitation intervention on quality of life among Chinese adults with hearing loss. We hope that it would help improve the well-being for Chinese adults and provide references in policy and practice for China and other countries. Trial registration Chinese Clinical Trial Registry ChiCTR1900024739. Registered on 26 July 2019.

scholarly journals Application of Zizao Yangrong Granules for Treating Targeted Drugs–Related Skin Xerosis: A Randomized Double-Blinded Controlled Study

2020 ◽  
Vol 19 ◽  
pp. 153473542092483
Author(s):  
Yan Mei Peng ◽  
Hua Duan ◽  
Jingyi Zhang ◽  
Chenyao Sun ◽  
Xu Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Treatment Group ◽  
Growth Factor Receptor ◽  
Controlled Study ◽  
Control Group ◽  
Targeted Drugs ◽  
Liver And Kidney ◽  
Double Blinded ◽  
And Control

Background: Dermatologic toxicities are the most common side effects associated with the targeted drugs epidermal growth factor receptor inhibitors (EGFRIs), in which xerosis commonly complicated by pruritus severely disturbs the quality of life. The study has observed the curative effect of Zizao Yangrong granules (ZYG) from Chishui Xuanzhu in the treatment of EGFRIs-related xerosis and pruritus, as well as evaluating the safety of the prescription. Methods: Patients (n = 68) who had xerosis after using EGFRIs were enrolled and then randomly divided into the treatment group and control group, respectively, receiving ZYG and placebo granules combined with vitamin E ointment. The intervention lasted 4 weeks. Changes in xerosis and pruritus were observed, and blood routine examination as well as liver and kidney function are observed as safety indexes. The water content of skin and qualify of life were observed. Results: A total of 66 out of 68 patients finished the study with 34 patients in each group. The effective rates of xerosis among the treatment group and control group were 84.8% and 69.7% after 2 weeks’ treatment ( P < .05), while they were 84.8% and 75.8% after 4 weeks’ treatment ( P < .05). The patients in the experimental group had better quality of life than that in the control group ( P = .045). Conclusion: ZYG can effectively improve the skin dryness associated with EGFRIs, and significantly improve the quality of life of patients with good safety; however, larger randomized controlled trials are needed to verify these findings.

scholarly journals An Alternative to Current Therapies of Functional Dyspepsia: Self-Administrated Transcutaneous Electroacupuncture Improves Dyspeptic Symptoms

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Ting Ji ◽  
Xueliang Li ◽  
Lin Lin ◽  
Liuqin Jiang ◽  
Meifeng Wang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastric Emptying ◽  
Functional Dyspepsia ◽  
Therapeutic Potential ◽  
Treatment Options ◽  
Treatment Method ◽  
Gastric Accommodation ◽  
Dyspeptic Symptoms ◽  
New Treatment

Functional dyspepsia is of high prevalence with little treatment options. The aim of this study was to develop a new treatment method using self-management transcutaneous electroacupuncture (TEA) for functional dyspepsia (FD). Twenty-eight patients with FD were enrolled and underwent a crossover clinical trial with 2-week TEA at ST36 and PC6 and 2-week sham-TEA at nonacupuncture sham-points. Questionnaires were used to assess symptoms of dyspepsia and quality of life. Physiological testing included gastric emptying and electrogastrography. It was found that (1) TEA but not sham-TEA significantly improved dyspeptic symptoms and 4 domains in quality of life; improvement was also noted in self-rated anxiety and depression scores; (2) gastric emptying was significantly and substantially increased with 2-week TEA but not sham-TEA; and (3) gastric accommodation was also improved with TEA but not sham-TEA, reflected as increased ingested nutrient volumes at the levels of satiety and maximum tolerance. These findings suggest a therapeutic potential of self-administrated TEA method for functional dyspepsia, possibly attributed to improvement in gastric motility.

scholarly journals Efficacy of air purifier therapy for patients with allergic asthma

2019 ◽  
Author(s):  
Jiaying LUO ◽  
Zhao Chen ◽  
Li-li Ou ◽  
Xin-yuan Lin ◽  
Hai-cheng Liu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Treatment Group ◽  
Allergic Asthma ◽  
Asthma Control ◽  
Control Group ◽  
Control Test ◽  
Asthma Control Test ◽  
Air Purifier ◽  
Der P1

Abstract Background and Objectives: The prevalence of allergic disease, which has a severely negative effect on patients' quality of life, has been increasing in recent years. Environmental intervention is internationally regarded as a feasible method for controlling asthma. Thus, this study aimed to evaluate the efficacy of air purifier therapy for patients with allergic asthma. Methods: In total, 38 subjects were divided into a treatment group and a control group. All subjects were under the age of eighteen years and had been clinically diagnosed with allergic asthma. The treatment group used High Efficiency Particulate Air (HEPA) air purifiers for six consecutive months, and the control group did not use the air filters. Particulate matter (PM) data and dust samples (bedding and a static point) were collected from the subjects' bedrooms before they started to use the air purifiers and each month thereafter. Simultaneously, the subjects were asked to complete a questionnaire for the Asthma Control Test (ACT) or Childhood Asthma Control Test (C-ACT). Fractional exhaled nitric oxide (FENO) tests were performed at the start and end of the study. The concentrations of Der p1 and Der f1 were measured in the dust samples. Results: 1. After utilizing an air purifier, the concentrations of house dust mite (HDM) allergens (Der p1+ Der f1) in the bedding and static samples decreased by 68.3% and 71.0%, respectively. In addition, the PMindoor/outdoor levels significantly decreased. 2. The ACT and C-ACT scores in the treatment group maintained a steady significant upward trend. 3. At the end of the study, the FENO levels in both groups were lower, although the differences were not significant. Conclusions: HEPA air purifiers are able to decrease indoor HDM allergen and PM levels and improve quality of life in allergic asthma patients.

scholarly journals Central venous catheter based closed thoracic drainage in the treatment of tuberculous pleuritis

2019 ◽  
Vol 35 (4) ◽  
Author(s):  
Ling Song ◽  
Yueling Zhang ◽  
Qiong Jia
Keyword(s):  
Quality Of Life ◽  
Treatment Group ◽  
Central Venous Catheter ◽  
Venous Catheter ◽  
Control Group ◽  
Central Venous ◽  
Thoracic Drainage ◽  
Significant Difference ◽  
Tuberculous Pleurisy

Objective: To explore the clinical effect of central venous catheter closed thoracic drainage in the treatment of tuberculous pleurisy. Methods: One hundred and four patients with tuberculous pleurisy who were admitted to Binzhou People’s Hospital from August 2016 to August 2017 were divided into a control group and a treatment group according to random number table method, 52 each. The control group was treated with conventional pleural puncture and drainage, while the treatment group was treated with closed central venous catheter based thoracic drainage. The clinical efficacy, improvement time of clinical symptoms, total volume of drainage, pleural thickness, and improvement of quality of life and occurrence of adverse reactions were compared between the two groups. Results: Pleural effusion, fever and chest tightness of the treatment group disappeared earlier (P<0.05); the hospitalization time in the treatment group was less than that in the control group (P<0.05); the total amount of drainage in the treatment group was lower than that in the control group (P<0.05); the pleural thickness of the treatment group was higher than that in the control group (P<0.05); the quality of life score in the treatment group was significantly higher than that in the control group (P<0.05). The total effective rates of the treatment group and the control group were 93.5% and 85%, respectively, with a significant difference (P<0.05). The incidence of adverse reactions in the treatment group was significantly lower than that in the control group, with a significant difference (P<0.05). Conclusion: Central venous catheter based closed thoracic drainage is more effective than conventional thoracic puncture and drainage in the treatment of tuberculous pleurisy. It can accelerate the improvement of clinical symptoms, improve the quality of life of patients, and reduce the incidence of complications. It is worth popularizing and applying. doi: https://doi.org/10.12669/pjms.35.4.63 How to cite this:Song L, Zhang Y, Jia Q. Central venous catheter based closed thoracic drainage in the treatment of tuberculous pleuritis. Pak J Med Sci. 2019;35(4):---------. doi: https://doi.org/10.12669/pjms.35.4.63 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Effects of upper cervical translatoric mobilization on headache, quality of life, cervical mobility and pressure pain threshold in patients with cervicogenic headache: A randomized controlled trial.

2020 ◽  
Author(s):  
Miguel Malo-Urriés ◽  
José Miguel Tricás-Moreno ◽  
Elena Estébanez-de-Miguel ◽  
Elena Bueno-Gracia ◽  
Pablo Fanlo-Mazas ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Treatment Group ◽  
Pain Threshold ◽  
Pressure Pain Threshold ◽  
Cervicogenic Headache ◽  
Control Group ◽  
Pressure Pain ◽  
Upper Cervical ◽  
Related Quality

Abstract Objective The purpose of this study was to evaluate the effects of upper cervical translatoric spinal mobilization (UC-TSM) on headache, quality of life, cervical mobility and pressure pain threshold in subjects with cervicogenic headache (CEH). Methods Eighty-two volunteers (41.5 ± 15.3 years; 20 males and 62 females) with CEH participated in the study and were randomly assigned to control or treatment group. The treatment group received 3 sessions of UC-TSM and the control group remained the same sessions, in the same position and time but received no treatment. Primary outcomes were Headache Impact Test for headache-related quality of life and flexion-rotation test for upper cervical mobility. Secondary outcomes included intensity, frequency and duration of headache, general cervical mobility and pressure pain thresholds over cervical spine. They were measured at baseline, at the end of the treatment and one month after the intervention. Results UC-TSM group increased significantly headache-related quality of life (p < .001; d = .857). Headache intensity, frequency and duration improved in UC-TSM group (p = .000-.013), in contrast to control group which did not obtain significant changes (p = .234-.965). UC-TSM group presented significant increases in upper cervical mobility (p < .001). Between-group effect sizes were considered large at T1 (d = 0.90–1.21) and moderate to large at T2 (d = 0.78–1.17). Conclusions Three sessions of UC-TSM increased headache-related quality of life and upper cervical mobility in subjects with CEH. Intensity, duration and frequency of headache, cervical mobility and PPT also improved. Further research considering the limitations of the present clinical trial is required to confirm this tendency.

scholarly journals PENGARUH PEMBERIAN INHALASI KOMBINASI SALMETEROL/FLUTIKASON PROPIONAT TERHADAP KUALITAS HIDUP PENDERITA PENYAKIT PARU OBSTRUKTIF KNONIK STABIL

2019 ◽  
Vol 1 (2) ◽  
pp. 28-33
Author(s):  
Refi Sulistiasari
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Treatment Group ◽  
Control Group ◽  
Copd Assessment Test ◽  
Copd Patients ◽  
Significant Difference ◽  
Inhaled Therapy ◽  
St George's Respiratory Questionnaire

It is known that inflammation is the underlying cause of COPD, and this affects to quality of life of the patient. Provision of inhaled therapy combination of LABA and corticosteroids is one of therapy in pharmacology of stable PPOK patients. The aim of this study was to know the benefits of inhalation of 50 g / fluticasone propionate 500 g inhibition in stable COPD patients. The research design is clinical trial. The study was conducted for 3 months and was performed on 26 stable COPD patients divided into two groups: 15 patients for the treatment group and 15 patients for the control group. After the measurements were obtained, there was a significant difference in the quality of life as measured by St. George's Respiratory Questionnaire (SGRQ) (p = 0.001) and COPD Assessment Test (CAT) (0.001) measurements were made twice on the first and thirtieth days.

scholarly journals Pengaruh Terapi Progressive Muscle Relaxation Terhadap Kecemasan Dan Kualitas Hidup Pada Pasien Diabetes Mellitus Tipe 2 Di RS Muhammadiyah Lamongan

2018 ◽  
Vol 2 (1) ◽  
pp. 45
Author(s):  
Adbul Rokhman ◽  
Lilik Supriati
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Treatment Group ◽  
Muscle Relaxation ◽  
Progressive Muscle Relaxation ◽  
Control Group ◽  
Relaxation Therapy

ABSTRAKPenyakit diabetes mellitus yang tidak bisa disembuhkan secara total sering berdampak pada terjadinya kecemasan dan penurunan kualitas hidup. Untuk menurunkan kecemasan dan meningkatkan kualitas hidup pasien dapat dilakukan terapi progressive muscle relaxation. Penelitian ini bertujuan untuk mengetahui pengaruh terapi PMR (Progressive Muscle Relaxation) terhadap kecemasan dan kualitas hidup pada pasien diabetes mellitus tipe 2 di RS Muhammadiyah Lamongan. Metode quasi eksperimental dengan pendekatan pre-post test control group design dengan simple random sampling. Jumlah sampel 50 orang dibagi menjadi 2 kelompok perlakuan dan kontrol masing-masing 25 orang. Alat ukur menggunakan kuisioner HARS untuk kecemasan dan DQOL (Diabetes Quality of Life) untuk kualitas hidup. Hasil analisis kecemasan dengan uji t pada kelompok perlakuan p 0,000, kelompok kontrol p 0,746. Analisis kualitas hidup pada kelompok perlakuan nilai p 0,000 dan kelompok kontrol p 0,098. Perbedaan kecemasan pada kelompok perlakuan dan kontrol p 0,019. Perbedaan kualitas hidup pada kelompok perlakuan dan kontrol p 0,076. Pengaruh faktor pendidikan terhadap kualitas hidup pada pasien DM tipe 2 sesudah diberikan terapi progressive muscle relaxation sebesar 4,9 % setelah dikontrol variabel lain. Terapi progressive muscle relaxation efektif untuk menurunkan kecemasan dan efektif untuk meningkatkan kualitas hidup pasien DM tipe 2. Terapi progressive muscle relaxation dapat dimasukkan kedalam intervensi keperawatan pada pelayanan rumah sakit. Kata Kunci: Diabetes Mellitus tipe 2, Kecemasan, Kualitas Hidup, Terapi Progressive Muscle Relaxation ABSTRACTDiabetes mellitus which cannot be cured completely often have an impact on the occurrence of anxiety and reduced quality of life. To reduce anxiety and improve the quality of life of patients can use progressive muscle relaxation therapy. This study aims to determine the effect of PMR therapy (Progressive Muscle Relaxation) in anxiety and quality of life in patients with type 2 diabetes mellitus in Lamongan Muhammadiyah Hospital. Quasi-experimental method with the approach of pre-posttest control group design with simple random sampling. Number of samples 50  people  were   divided  into   two   treatment   groups  and   control  each   25   people.  HARS questionnaire instrument used for measuring anxiety and DQOL (Diabetes Quality of Life) for measuring quality of life. Results of the analysis by the t-test anxiety in the experimental group p0.000, 0.746 p control group. Analysis of the quality of life in the treatment group p values of 0.000 and 0.098 p control group. Anxiety differences in the treatment group and the control p0.019. Differences in the quality of life in the treatment group and the control p 0.076. Results of the analysis by the t-test anxiety in the experimental group p 0.000, 0.746 p control group. Analysis of the quality of life in the treatment group p values of 0.000 and 0.098 p control group. Anxiety differences in the treatment group and the control p 0.019. Differences in the quality of life in the treatment group and the control p 0.076. Educational factors influence the quality of life in patients with type 2 diabetes mellitus after progressive muscle relaxation therapy by 4.9% after controlling other variables. Progressive muscle relaxation therapy is effective to reduce anxiety and effective to improve the quality of life of patients with type 2 diabetes. Progressive muscle relaxation therapy can be incorporated into nursing interventions on hospitals.Keyword : Type 2 Diabetes Mellitus, anxiety, quality of life, progressive muscle relaxation therapy

scholarly journals Herbal MedicineCordyceps sinensisImproves Health-Related Quality of Life in Moderate-to-Severe Asthma

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Ningqun Wang ◽  
Jie Li ◽  
Xiaobo Huang ◽  
Wenqiang Chen ◽  
Yujing Chen
Keyword(s):  
Quality Of Life ◽  
Treatment Group ◽  
Lung Function ◽  
Severe Asthma ◽  
Cordyceps Sinensis ◽  
Control Group ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Moderate-to-severe asthma has a substantial impact on the health-related quality of life (HR-QOL) of the patients.Cordyceps sinensisis a traditional Chinese medicine that is evaluated clinically for the treatment of many diseases, such as chronic allograft nephropathy, diabetic kidney disease, and lung fibrosis. In order to investigate the effects ofCordyceps sinensison patients with moderate-to-severe persistent asthma, 120 subjects were randomized to receive Corbin capsule containingCordyceps sinensisfor 3 months (treatment group,n=60), whereas the control group (n=60) did not receive treatment with Corbin capsule. Inhaled corticosteroid and as-neededβ-agonists were used in the treatment of both groups. HR-QOL was measured with the Juniper’s Asthma Quality of Life Questionnaire (AQLQ). The incidence of asthma exacerbation, pulmonary function testing, and serum measurements of inflammatory mediators were also evaluated. The results showed that the treatment group indicated a significant increase in AQLQ scores and lung function compared with the control group. The expression levels of the inflammation markers IgE, ICAM-1, IL-4, and MMP-9 in the serum were decreased and IgG increased in the treatment group compared with the control group. Therefore, the conclusion was reached that a formulation ofCordyceps sinensisimproved the HR-QOL, asthma symptoms, lung function, and inflammatory profile of the patients with moderate-to-severe asthma. This trial is registered withChiCTR-IPC-16008730.

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