scholarly journals Synthesis of Silver Abietate as an Antibacterial Agent for Textile Applications

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
A. Yıldız ◽  
M. Değirmencioğlu
Keyword(s):  
Textile Industry ◽  
Antibacterial Agent ◽  
Abietic Acid ◽  
Antibacterial Activities ◽  
Test Method ◽  
Gram Positive Bacteria ◽  
H Nmr ◽  
Agar Diffusion Test ◽  
New Compounds ◽  
First Time

This study explored the potential use of new silver abietate obtained from abietic acid as an antibacterial agent for textile applications. Synthesis, structure, and antibacterial studies of silver abietate compound are reported. Silver complex was obtained reacting abietic acid with silver. The new compounds were characterized by1H NMR,13C NMR, DEPT, IR, UV, and ESI-MS techniques which support the proposed structures. The new Ag abietate complex has no environmental hazard, its antibacterial activities were evaluated after being applied to cotton fabric by padding process according to the JIS L 1902-2008 agar diffusion test method and against three Gram-negative and three Gram-positive bacteria, respectively. Stability of antibacterial effect after repeated washings (3, 5, 10, and 20) was also tested which indicated that the synthesized silver abietate compound could be used as a new antibacterial agent in textile industry. In this way, the compound has been synthesized the first time in the literature and the applications have been investigated.

scholarly journals Sesquiterpenoids From the Antarctic Fungus Pseudogymnoascus sp. HSX2#-11

2021 ◽  
Vol 12 ◽  
Author(s):  
Ting Shi ◽  
Xiang-Qian Li ◽  
Li Zheng ◽  
Ya-Hui Zhang ◽  
Jia-Jia Dai ◽  
...  
Keyword(s):  
Pathogenic Fungi ◽  
Antibacterial Activities ◽  
Aeromonas Salmonicida ◽  
Systematic Research ◽  
Cytotoxic Activities ◽  
Hepg2 Cell Lines ◽  
New Compounds ◽  
The Antarctic ◽  
First Time ◽  
Hepatoma Hepg2

The fungal strains Pseudogymnoascus are a kind of psychrophilic pathogenic fungi that are ubiquitously distributed in Antarctica, while the studies of their secondary metabolites are infrequent. Systematic research of the metabolites of the fungus Pseudogymnoascus sp. HSX2#-11 led to the isolation of six new tremulane sesquiterpenoids pseudotremulanes A–F (1–6), combined with one known analog 11,12-epoxy-12β-hydroxy-1-tremulen-5-one (7), and five known steroids (8–12). The absolute configurations of the new compounds (1–6) were elucidated by their ECD spectra and ECD calculations. Compounds 1–7 were proved to be isomeride structures with the same chemical formula. Compounds 1/2, 3/4, 1/4, and 2/3 were identified as four pairs of epimerides at the locations of C-3, C-3, C-9, and C-9, respectively. Compounds 8 and 9 exhibited cytotoxic activities against human breast cancer (MDA-MB-231), colorectal cancer (HCT116), and hepatoma (HepG2) cell lines. Compounds 9 and 10 also showed antibacterial activities against marine fouling bacteria Aeromonas salmonicida. This is the first time to find terpenoids and steroids in the fungal genus Pseudogymnoascus.

scholarly journals Comparative Study of Chemical Composition and Biological Activity of Yellow, Green, Brown, and Red Brazilian Propolis

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Christiane Schineider Machado ◽  
João Benhur Mokochinski ◽  
Tatiana Onofre de Lira ◽  
Fátima de Cassia Evangelista de Oliveira ◽  
Magda Vieira Cardoso ◽  
...  
Keyword(s):  
Biological Activity ◽  
Chemical Composition ◽  
Quality Standard ◽  
Antimicrobial Activities ◽  
Mato Grosso ◽  
Gram Positive Bacteria ◽  
H Nmr ◽  
Chemical Profiles ◽  
Brazilian Propolis ◽  
First Time

The chemical composition and biological activity of a sample of yellow propolis from Mato Grosso do Sul, Brazil (EEP-Y MS), were investigated for the first time and compared with green, brown, and red types of Brazilian propolis and with a sample of yellow propolis from Cuba. Overall, EEP-Y MS had different qualitative chemical profiles, as well as different cytotoxic and antimicrobial activities when compared to the other types of propolis assessed in this study and it is a different chemotype of Brazilian propolis. Absence of phenolic compounds and the presence of mixtures of aliphatic compounds in yellow propolis were determined by analysing1H-NMR spectra and fifteen terpenes were identified by GC-MS. EEP-Y MS showed cytotoxic activity against human tumour strain OVCAR-8 but was not active against Gram-negative or Gram-positive bacteria. Our results confirm the difficulty of establishing a uniform quality standard for propolis from diverse geographical origins. The most appropriate pharmacological applications of yellow types of propolis must be further investigated.

scholarly journals Biogenetic Conversion of Wyerone and Dihydrowyerone into Wyerone Epoxide in Vicia faba Cotyledons and Screening of Antibacterial Activity

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Nedhal A. Al-Douri ◽  
Randa N. Haddadin ◽  
Ashok K. Shakya ◽  
Ghaleb A. Oriquat
Keyword(s):  
Antibacterial Activity ◽  
Vicia Faba ◽  
Antibacterial Activities ◽  
Antimicrobial Activities ◽  
Stress Factors ◽  
Gram Positive Bacteria ◽  
The Family ◽  
Zones Of Inhibition ◽  
Plant Produce ◽  
First Time

Background. Vicia faba is a plant that belongs to the family Fabaceae. Cotyledons of this plant produce compounds called phytoalexins as a result of fungal and bacterial infection or stress factors. The phytoalexins are furanoacetylenic compounds. They include wyerone, wyerol, wyerone acid, their dihydro derivatives, and wyerone epoxide. These compounds have antimicrobial activities mainly against fungi. Objective. The purpose of this study was to elucidate the biogenetic conversion of wyerone and dihydrowyerone to wyerone epoxide in V. faba and to investigate the antibacterial activities of some of these phytoalexins. Materials and Methods. Seeds of Vicia faba were used. Labelled wyerone and dihydrowyerone were obtained by treating CuCl2-induced cotyledons with sodium (2-14C) acetate and separated by TLC and HPLC. Labelled wyerone and dihydrowyerone were then applied to induced bean cotyledons to establish any possible interconversion to wyerone epoxide. Antibacterial activity of wyerone, wyerone acid, and wyerone epoxide was investigated by disc diffusion test against a panel of microorganisms. Zones of inhibition were reported. Results. The radiolabeling studies showed that 12.4% of 14C-wyerone, and 6.01% of 14C-dihydrowyerone were incorporated into wyerone epoxide. This indicates that wyerone epoxide was most probably derived from wyerone and dihydrowyerone. In addition, a new compound, 11-hydroxywyerone was isolated for the first time. Additionally, this study showed that wyerone, wyerone epoxide, and wyerone acid had no antibacterial activity against Gram-negative bacteria but were active against Gram-positive bacteria.

Synthesis and properties of axially substituted zirconium(IV) and hafnium(IV) phthalocyanines with organic ligands

2001 ◽  
Vol 05 (10) ◽  
pp. 731-734 ◽  
Author(s):  
L. A. TOMACHYNSKI ◽  
V. YA. CHERNII ◽  
S. V. VOLKOV
Keyword(s):  
Elemental Analysis ◽  
Water Soluble ◽  
Organic Ligands ◽  
Axial Position ◽  
H Nmr ◽  
New Compounds ◽  
First Time

Water-soluble phthalocyaninato zirconium(IV) and hafnium(IV) complexes have been synthesized for the first time. An increased solubility in comparison to PcZrCl 2 and PcHfCl 2 was caused by the introduction of gallic, 1,8-dihydroxynaphthalene-3,6-disulfonic (chromotropic), and 5-sulfosalicylic acids in the axial position. The new compounds were characterized by 1 H NMR, IR, UV-vis and elemental analysis.

Three New Abietane-Type Diterpenoids from Plectranthus africanus and Their Antibacterial Activities

Planta Medica ◽  
2017 ◽  
Vol 84 (01) ◽  
pp. 59-64 ◽  
Author(s):  
Raïssa Nzogong ◽  
Blaise Nganou ◽  
Alex Tedonkeu ◽  
Maurice Awouafack ◽  
Mathieu Tene ◽  
...  
Keyword(s):  
Minimal Inhibitory Concentration ◽  
Inhibitory Concentration ◽  
Methanol Extract ◽  
2D Nmr ◽  
Antibacterial Activities ◽  
Gram Negative Bacteria ◽  
Gram Positive Bacteria ◽  
Whole Plant ◽  
New Compounds ◽  
And Staphylococcus Aureus

AbstractThree new abietane-type diterpenoids, plectranthroyleanones A – C (1 – 3), together with five known compounds (4 – 8) were isolated from the methanol extract of the whole plant of Plectranthus africanus using column chromatography techniques. The structures of the new compounds were elucidated using a combination of 1D and 2D NMR and HRESIMS analyses. Compound 1 exhibited weak activities with minimal inhibitory concentration values of 75 µg/mL against gram-positive bacteria, Bacillus subtilis and Staphylococcus aureus, and 150 µg/mL against two gram-negative bacteria, Pseudomonas aeruginosa and Klebsiella pneumoniae, respectively, while 2 and 3 had moderate antibacterial activity against K. pneumoniae with a minimal inhibitory concentration value of 37.5 µg/mL.

scholarly journals Investigation of the antibacterial activity of new quinazoline derivatives against methicillin and quinolone resistant Staphylococcus aureus

2020 ◽  
Vol 44 (5-6) ◽  
pp. 315-321
Author(s):  
Amit B Patel
Keyword(s):  
Coupling Reaction ◽  
Antibacterial Activities ◽  
Multidrug Resistant ◽  
Gram Positive Bacteria ◽  
H Nmr ◽  
Cross Coupling Reaction ◽  
Affect Cell Viability ◽  
Quinazoline Derivatives ◽  
Different Strains ◽  
C Nmr

A series of 1,3,4-oxadiazole-fused and piperazine-fused quinazoline derivatives is synthesized and evaluated as antibacterial agents. The synthetic protocol involves an efficient Suzuki C–C cross-coupling reaction on the quinazoline ring followed by formation of 1,3,4-oxadiazole intermediates. These are further treated with piperazine bases in the presence of formalin in methanol to furnish the final N-Mannich products. The majority of these compounds show potent antibacterial activities against several different strains of Gram-positive bacteria including multidrug-resistant clinical isolates. The cytotoxic activity assay demonstrates that the synthesized compounds do not affect cell viability on Human cervical (HeLa) cells at their minimum inhibitory concentrations. The newly synthesized compounds are characterized by infrared spectroscopy, 1H NMR, 13C NMR, mass spectrometry, and elemental analysis.

Resorcylic Acid Lactones Produced by an Endophytic Penicillium ochrochloron Strain from Kadsura angustifolia

Planta Medica ◽  
2020 ◽  
Author(s):  
Hong Chuan Song ◽  
Dan Qin ◽  
Hai Yang Liu ◽  
Jin Yan Dong ◽  
Chuan You ◽  
...  
Keyword(s):  
Spectroscopic Analysis ◽  
Tumor Cell Line ◽  
Antibacterial Activities ◽  
Preparative Hplc ◽  
Solid Culture ◽  
Ic50 Value ◽  
Resorcylic Acid Lactones ◽  
New Compounds ◽  
First Time

AbstractFour new β-resorcylic acid lactones, including penochrochlactone A (2), 4-O-desmethyl-aigialomycin B (4), and penochrochlactones C and D (5 and 6), two compounds isolated from a natural source for the first time, 5α, 6β-acetonide-aigialomycin B (1) and penochrochlactone B (3), together with six known compounds, aigialomycin F (7), aigialomycins A, B, and D (8–10), zeaenol (11), and oxozeaenol (12), were isolated from a mycelial solid culture of the endophytic fungus Penicillium ochrochloron SWUKD4.1850 from the medicinal plant Kadsura angustifolia by sequential purification over silica gel, Sephadex LH-20 column chromatography, and preparative HPLC. Their structures were elucidated by extensive spectroscopic analysis and chemical conversions. In addition, all the new compounds were evaluated for their cytotoxic and antibacterial activities in vitro. Penochrochlactone C (5) displayed moderate cytotoxicity against the HeLa tumor cell line with an IC50 value of 9.70 µM. In the antibacterial assays, compounds 4 – 6 exhibited moderate activities against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa with MIC values between 9.7 and 32.0 µg/mL.

scholarly journals Secondary Metabolites with Antimicrobial Activities from Chamaecyparis obtusa var. formosana

Molecules ◽  
2022 ◽  
Vol 27 (2) ◽  
pp. 429
Author(s):  
Ming-Der Wu ◽  
Ming-Jen Cheng ◽  
Jih-Jung Chen ◽  
Nanthaphong Khamthong ◽  
Wen-Wei Lin ◽  
...  
Keyword(s):  
Spectroscopic Analysis ◽  
High Resolution Mass Spectrometry ◽  
Chamaecyparis Obtusa ◽  
Antibacterial Activities ◽  
Antimicrobial Activities ◽  
The Past ◽  
Nmr Data ◽  
The Mean ◽  
New Compounds ◽  
First Time

Seven new compounds, including one dimer novel skeleton, chamaecyformosanin A (1); three diterpenes, chamaecyformosanins B–D (2-4); one sesquiterpene, chamaecyformosanin E (5); and two monoterpenes, chamaecyformosanins F and G (6 and 7) were isolated from the methanol extract of the bark of Chamaecyparis obtusa var. formosana. Their structures were established by the mean of spectroscopic analysis and the comparison of NMR data with those of known analogues. Their structures were elucidated on the basis of physicochemical evidence, in-depth NMR spectroscopic analysis, and high-resolution mass spectrometry. Furthermore, the isolated compounds were subjected to an evaluation of their antimicrobial activity. Metabolites 1, 3, and 4 present antibacterial activities. It is worth mentioning that the chemical composition of the bark of C. obtusa var. formosana has never been studied in the past. This is the first time the barks from C. obtusa var. formosana were studied and two new skeleton compounds, 1 and 7, were obtained.

Antibacterial Activities of Sirih Merah (Piper crocatum) Leaf Extracts

2019 ◽  
Vol 5 (3) ◽  
pp. 1-10
Author(s):  
Puspa Julistia Puspita ◽  
Mega Safithri ◽  
Nirmala Peni Sugiharti
Keyword(s):  
Escherichia Coli ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Agent ◽  
Leaf Extract ◽  
Antibacterial Activities ◽  
Leaf Extracts ◽  
Herbal Plants

Piper crocatum is one of medicinal herbal plants with a large number of benefits. Usually herbal plants have activity as antibacterial agent. Therefore, the objectives of this research were to obtain information on antibacterial activities of the leaf extracts of Piper crocatum againts four types of bacteria, in that Staphylococcus, Bacillus substilis, Escherichia coli, and Pseudomonas aeruginosa and then to analyze the phytochemistry of the leaf extracts of Piper crocatum. The leaves of Piper crocatum were extracted by maceration and reflux using ethanol 30%. The assays of the antibacterial activities and phytochemistry on the extracts were carried out using the method of Maria Bintang. Results showed that the yield of the extraction using ethanol by maceration method was 20.8%. Meanwhile, using the reflux method, the yield was obtained about 26.25%. The phytochemistry analysis showed that the leaf extracts of Piper crocatum contained alkaloid, steroid and tanin. According to this study, it was found that the leaf extract of Piper crocatum can be used to inhibit the growth of B. subtilis and P. aeuruginosa, but can not inhibit the growth of E.coli and S. aureus.

Chemical Constituents and Antibacterial Activity of Cissus Aralioides.

2020 ◽  
Vol 17 ◽  
Author(s):  
Balogun Olaoye Solomon ◽  
Ajayi Olukayode Solomon ◽  
Owolabi Temitayo Abidemi ◽  
Oladimeji Abdulkarbir Oladele ◽  
Liu Zhiqiang
Keyword(s):  
Plant Extract ◽  
Chemical Constituents ◽  
Ethyl Acetate Fraction ◽  
Antibacterial Activities ◽  
Sub Saharan Africa ◽  
Chromatographic Purification ◽  
Whole Plant ◽  
Sub Saharan ◽  
First Time

: Cissus aralioides is a medicinal plant used in sub-Saharan Africa for treatment of infectious diseases; however the chemical constituents of the plant have not been investigated. Thus, in this study, attempt was made at identifying predominant phytochemical constituents of the plant through chromatographic purification and silylation of the plant extract, and subsequent characterization using spectroscopic and GC-MS techniques. The minimum inhibitory concentration (MICs) for the antibacterial activities of the plant extract, chromatographic fractions and isolated compounds were also examined. Chromatographic purification of the ethyl acetate fraction from the whole plant afforded three compounds: β-sitosterol (1), stigmasterol (2) and friedelin (3). The phytosterols (1 and 2) were obtained together as a mixture. The GC-MS analysis of silylated extract indicated alcohols, fatty acids and sugars as predominant classes, with composition of 24.62, 36.90 and 26.52% respectively. Results of MICs indicated that friedelin and other chromatographic fractions had values (0.0626-1.0 mg/mL) comparable with the standard antibiotics used. Characterization of natural products from C. aralioides is being reported for the first time in this study.

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