scholarly journals Complete Disappearance of Choroidal Metastasis from Lung Adenocarcinoma Treated with Bevacizumab and Chemotherapy

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Hampig Raphael Kourie ◽  
Joelle Antoun ◽  
Alexandre Schakal ◽  
Elie Nasr ◽  
Marwan Sahyoun ◽  
...  

Choroidal metastasis from lung cancer is uncommon. We report a case of choroidal metastasis as an inaugural manifestation of lung adenocarcinoma, successfully treated by docetaxel, cisplatinum, and intravenous bevacizumab as an antiangiogenesis therapy. A complete remission was obtained after 4 cycles and maintained after six cycles. This case report demonstrates the importance of the systemic bevacizumab and chemotherapy in the treatment of choroidal metastasis from adenocarcinoma of the lung.

2018 ◽  
Vol 25 (8) ◽  
pp. 2007-2009 ◽  
Author(s):  
Kevin Sullivan ◽  
Chung-Shien Lee

Pemetrexed is an antifolate metabolite used to treat non-small cell lung cancer in the adjuvant and advanced setting. It is commonly known to cause rash, diarrhea, fatigue, mucositis, and myelosuppression. We report a case of a patient receiving adjuvant cisplatin and pemetrexed for non-small cell lung adenocarcinoma and experienced severe rhabdomyolysis.


2017 ◽  
Vol 20 ◽  
pp. 125-128
Author(s):  
Aixa Dones Rodríguez ◽  
Kelvin Rivera Manzano ◽  
Ricardo Fernández González ◽  
José R. Adorno Fontánez ◽  
Ricardo A. Hernández ◽  
...  

2012 ◽  
Vol 4 (2) ◽  
pp. 339-342 ◽  
Author(s):  
S Salah ◽  
J Khader ◽  
Y Yousef ◽  
A Salem ◽  
M Al-Hussaini ◽  
...  

Background: Choroidal metastasis as an initial presenting feature of metastatic lung cancer is exceedingly rare. External beam radiotherapy (EBRT) is an effective and widely accepted therapeutic modality. However, data addressing the effectiveness of other treatment strategies is limited. Herein, we present a patient with choroidal metastases secondary to lung cancer and review the relevant literature. Case report: A 25-year-old male presented with deterioration of vision. His evaluation revealed bilateral choroidal metastasis secondary to adenocarcinoma of the lung. Unfortunately, his vision continued to deteriorate despite treatment with EBRT and chemotherapy.Conclusion: Metastatic lung cancer can manifest with choroidal metastasis as an initial presentation.DOI: http://dx.doi.org/10.3126/nepjoph.v4i2.6559 Nepal J Ophthalmol 2012; 4 (2): 339-342  


2008 ◽  
Vol 13 (1) ◽  
pp. 79-81 ◽  
Author(s):  
Yuan‐Sheng Zang ◽  
Qing‐Yu Xiu ◽  
Zheng Fang ◽  
Bing Li ◽  
Tian‐Bao Xia

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Lauren Howdershelt ◽  
Michael J. Forte ◽  
Rahul G. Sangani

Paraneoplastic diarrhea is a commonly described complication of gastrointestinal tract or endocrine malignancies. It is an extremely rare complication of lung adenocarcinoma, with only one previously reported case in the literature. A 46-year-old female with newly diagnosed stage IVb lung adenocarcinoma presented to our intensive care unit in hypovolemic shock with symptoms suggestive of diabetes insipidus (DI) as well as profuse large volume watery diarrhea. Exhaustive serological and microbiological workup revealed the diarrhea to be paraneoplasitc in nature. This case represents the second known case of paraneoplastic diarrhea secondary to lung adenocarcinoma. Clinicians should be aware of this rare phenomenon.


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