scholarly journals A Case of Enlarged Intracranial Translucency in a Fetus with Blake’s Pouch Cyst

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Ambra Iuculano ◽  
Maria Angelica Zoppi ◽  
Rosa Maria Ibba ◽  
Giovanni Monni
Keyword(s):  
Spina Bifida ◽  
First Trimester ◽  
First Trimester Screening ◽  
Intracranial Translucency ◽  
Trimester Screening ◽  
Open Spina Bifida

The intracranial translucency (IT) is a recently introduced marker of open spina bifida (OSB). In this study, we describe a case of a fetus affected by Blake’s pouch cyst which showed alterations of BS/BSOB ratio at the first trimester screening.

scholarly journals P17.07: What is marker that will be used for first trimester screening of open spina bifida?

2012 ◽  
Vol 40 (S1) ◽  
pp. 237-238
Author(s):  
S. Buyukkurt ◽  
U. Kucukgoz ◽  
Gulec ◽  
R. Melekoglu ◽  
C. Evruke ◽  
...  
Keyword(s):  
Spina Bifida ◽  
First Trimester ◽  
First Trimester Screening ◽  
Trimester Screening ◽  
Open Spina Bifida

Towards Detecting Open Spina Bifida in the First Trimester: The Examination of the Posterior Brain

2015 ◽  
Vol 37 (4) ◽  
pp. 294-300 ◽  
Author(s):  
Dimitra Kappou ◽  
Ioannis Papastefanou ◽  
Athanasios Pilalis ◽  
Ioannis Kavalakis ◽  
Dimitrios Kassanos ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Ultrasound Examination ◽  
First Trimester ◽  
Current Evidence ◽  
Reference Ranges ◽  
R Ratio ◽  
Intracranial Translucency ◽  
Obstetric Population ◽  
A Prospective Study ◽  
Open Spina Bifida

Introduction: Our aim was to examine the value of indirect signs of open spina bifida in the mid-sagittal view of the posterior brain at the 11-13 weeks' ultrasound examination and to summarize the current evidence for the first-trimester diagnosis of spina bifida. Methods: This was a prospective study in routine obstetric population. The presence of four almost parallel lines (four-line view) in the posterior brain was recorded. Biparietal diameter (BPD), intracranial translucency (IT) and cisterna magna (CM) were measured. The ratio of IT to CM (R ratio) was calculated. Results: 2,491 pregnancies were examined prospectively. Updated reference ranges for IT and CM were constructed. There were 3 cases with open spina bifida, and the four-line view was abnormal in 2 of them. The abnormal fetuses had smaller BPD as well as pronounced reduction in the CM and increase in the R ratio. Discussion: Examination of the posterior brain was feasible in all fetuses in the setting of the routine 11-13 weeks' ultrasound examination. Indirect signs of spina bifida are visible in the mid-sagittal view of the posterior brain, and the assessment of these structures can be a reliable tool in the early identification of this abnormality.

344: The intracranial translucency as a means of first trimester screening for neural tube defects

2011 ◽  
Vol 204 (1) ◽  
pp. S140
Author(s):  
Jason D. Retzke ◽  
Christine M. Kovac ◽  
David S. McKenna ◽  
Catherine M. Downing ◽  
Jiri D. Sonek
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects ◽  
First Trimester ◽  
First Trimester Screening ◽  
Intracranial Translucency ◽  
Trimester Screening

Detection of Spina Bifida by First Trimester Screening – Results of the Prospective Multicenter Berlin IT-Study

2015 ◽  
Vol 38 (02) ◽  
pp. 151-157 ◽  
Author(s):  
Frank Chen ◽  
Janine Gerhardt ◽  
Michael Entezami ◽  
Rabih Chaoui ◽  
Wolfgang Henrich
Keyword(s):  
Spina Bifida ◽  
First Trimester ◽  
First Trimester Screening ◽  
Trimester Screening

Screening for Open Spina Bifida in a Routine Clinical Setting at the First-Trimester Scan: A Prospective Multicentre Cohort Study

2021 ◽  
pp. 1-7
Author(s):  
Johanna Tiechl ◽  
Samira Abdel Azim ◽  
Katharina Leitner ◽  
Astrid Berger ◽  
Irene Mutz-Dehbalaie ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Sensitivity And Specificity ◽  
First Trimester ◽  
Outcome Data ◽  
Prospective Multicentre Study ◽  
Multicentre Cohort Study ◽  
Routine Clinical Setting ◽  
Trimester Screening ◽  
Open Spina Bifida ◽  
Multicentre Cohort

<b><i>Objective:</i></b> The aim of this study was to investigate the performance of screening for open spina bifida (OSB) integrated into the routine first-trimester screening. <b><i>Method:</i></b> This is a prospective multicentre study of 4,755 women undergoing first-trimester ultrasound scans over a 4-year period. Measurements of the brainstem (BS) diameter and brainstem-to-occipital-bone (BSOB) distance were performed. The cisterna magna (CM) was measured in the tilted axial view. <b><i>Results:</i></b> Pregnancy outcome data were available for 4,658 fetuses included in this study. There were 5 fetuses with OSB, and in all of them, the BS/BSOB ratio and the CM measurements were abnormal. The sensitivity and specificity of a BS/BSOB ratio &#x3e;1 were 100%. The sensitivity of a CM width &#x3c;5th centile was 100%, and the specificity was 95.1%. In 4.6% of cases, the BS/BSOB ratio was between the 95th percentile and 1. In 87.1% of these cases, the CM was normal, and 12.9% had a CM below the 5th percentile. <b><i>Conclusion:</i></b> Screening for OSB is feasible in routine first-trimester scans. The BS/BSOB ratio shows a very good sensitivity and specificity. In cases with near-normal values for the BS/BSOB ratio, the CM width might be helpful for further assessment.

scholarly journals Intracranial translucency as a sonographic marker of open spina bifida at first trimester

2014 ◽  
Vol 1 (2) ◽  
pp. 92
Author(s):  
Taylan Kara
Keyword(s):  
Spina Bifida ◽  
Congenital Abnormality ◽  
Recent Literature ◽  
First Trimester ◽  
Second Trimester ◽  
Detection Rates ◽  
Intracranial Translucency ◽  
The Central Nervous System ◽  
The One ◽  
Open Spina Bifida

Spina bifida is the one of the most common severe congenital abnormality of the central nervous system. Scalloping of the frontal bones called “the lemon sign” and caudal displacement of the cerebellum called “the banana sign” are known as cranial signs of open spina bifida on ultrasonography at the second trimester. Although these signs are useful methods in diagnosing of open spina bifida in the second trimester, detection rates of open spina bifida by using these signs in the first trimester are low. Intracranial translucency is a new sonographic landmark that may be valuable for the early detection of open spina bifida in the first trimester. In this study using of intracranial translucency as a sonographic marker of open spina bifida at first trimester is discussed with the light of recent literature.

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