scholarly journals VP24.09: First trimester screening for open spina bifida: validation of measurement technique of the posterior fossa landmarks for open spina bifida

2020 ◽  
Vol 56 (S1) ◽  
pp. 161-161
Author(s):  
M. Bourdages ◽  
J.M. Walsh ◽  
J. Loeffler ◽  
J.M. Johnson
Keyword(s):  
Spina Bifida ◽  
Posterior Fossa ◽  
Measurement Technique ◽  
First Trimester ◽  
First Trimester Screening ◽  
Trimester Screening ◽  
Open Spina Bifida

scholarly journals A Case of Enlarged Intracranial Translucency in a Fetus with Blake’s Pouch Cyst

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Ambra Iuculano ◽  
Maria Angelica Zoppi ◽  
Rosa Maria Ibba ◽  
Giovanni Monni
Keyword(s):  
Spina Bifida ◽  
First Trimester ◽  
First Trimester Screening ◽  
Intracranial Translucency ◽  
Trimester Screening ◽  
Open Spina Bifida

The intracranial translucency (IT) is a recently introduced marker of open spina bifida (OSB). In this study, we describe a case of a fetus affected by Blake’s pouch cyst which showed alterations of BS/BSOB ratio at the first trimester screening.

scholarly journals P17.07: What is marker that will be used for first trimester screening of open spina bifida?

2012 ◽  
Vol 40 (S1) ◽  
pp. 237-238
Author(s):  
S. Buyukkurt ◽  
U. Kucukgoz ◽  
Gulec ◽  
R. Melekoglu ◽  
C. Evruke ◽  
...  
Keyword(s):  
Spina Bifida ◽  
First Trimester ◽  
First Trimester Screening ◽  
Trimester Screening ◽  
Open Spina Bifida

scholarly journals EP07.21: First trimester sonographic diagnosis of posterior fossa abnormalities: reference ranges and associated findings in fetuses with open spina bifida

2019 ◽  
Vol 54 (S1) ◽  
pp. 274-275
Author(s):  
R. Garcia Rodriguez ◽  
A. Romero Requejo ◽  
R. Garcia‐Delgado ◽  
J. Segura Gonzalez ◽  
M. De Luis Alvarado ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Posterior Fossa ◽  
First Trimester ◽  
Reference Ranges ◽  
Sonographic Diagnosis ◽  
Open Spina Bifida

Detection of Spina Bifida by First Trimester Screening – Results of the Prospective Multicenter Berlin IT-Study

2015 ◽  
Vol 38 (02) ◽  
pp. 151-157 ◽  
Author(s):  
Frank Chen ◽  
Janine Gerhardt ◽  
Michael Entezami ◽  
Rabih Chaoui ◽  
Wolfgang Henrich
Keyword(s):  
Spina Bifida ◽  
First Trimester ◽  
First Trimester Screening ◽  
Trimester Screening

Screening for Open Spina Bifida in a Routine Clinical Setting at the First-Trimester Scan: A Prospective Multicentre Cohort Study

2021 ◽  
pp. 1-7
Author(s):  
Johanna Tiechl ◽  
Samira Abdel Azim ◽  
Katharina Leitner ◽  
Astrid Berger ◽  
Irene Mutz-Dehbalaie ◽  
...  
Keyword(s):  
Spina Bifida ◽  
Sensitivity And Specificity ◽  
First Trimester ◽  
Outcome Data ◽  
Prospective Multicentre Study ◽  
Multicentre Cohort Study ◽  
Routine Clinical Setting ◽  
Trimester Screening ◽  
Open Spina Bifida ◽  
Multicentre Cohort

<b><i>Objective:</i></b> The aim of this study was to investigate the performance of screening for open spina bifida (OSB) integrated into the routine first-trimester screening. <b><i>Method:</i></b> This is a prospective multicentre study of 4,755 women undergoing first-trimester ultrasound scans over a 4-year period. Measurements of the brainstem (BS) diameter and brainstem-to-occipital-bone (BSOB) distance were performed. The cisterna magna (CM) was measured in the tilted axial view. <b><i>Results:</i></b> Pregnancy outcome data were available for 4,658 fetuses included in this study. There were 5 fetuses with OSB, and in all of them, the BS/BSOB ratio and the CM measurements were abnormal. The sensitivity and specificity of a BS/BSOB ratio &#x3e;1 were 100%. The sensitivity of a CM width &#x3c;5th centile was 100%, and the specificity was 95.1%. In 4.6% of cases, the BS/BSOB ratio was between the 95th percentile and 1. In 87.1% of these cases, the CM was normal, and 12.9% had a CM below the 5th percentile. <b><i>Conclusion:</i></b> Screening for OSB is feasible in routine first-trimester scans. The BS/BSOB ratio shows a very good sensitivity and specificity. In cases with near-normal values for the BS/BSOB ratio, the CM width might be helpful for further assessment.

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