scholarly journals Response to “Acute Hepatitis Induced by Lyprinol, the Lipid Extract of the Green-Lipped Mussel (Perna canaliculus), in a Patient with Polyarthrosis”

2014 ◽  
Vol 2014 ◽  
pp. 1-2
Author(s):  
Stephen P. Myers ◽  
Christopher J. Oliver
Keyword(s):  
Acute Hepatitis ◽  
Lipid Extract ◽  
Perna Canaliculus

scholarly journals Acute Hepatitis Induced by Lyprinol, the Lipid Extract of the Green-Lipped Mussel (Perna canaliculus), in a Patient with Polyarthrosis

2012 ◽  
Vol 2012 ◽  
pp. 1-2 ◽  
Author(s):  
Amr Abdulazim ◽  
Marion Hädrich ◽  
Matteo Montani ◽  
Nasser Semmo
Keyword(s):  
Rheumatoid Arthritis ◽  
Abdominal Pain ◽  
Side Effects ◽  
Acute Hepatitis ◽  
Lipid Extract ◽  
Complementary Treatment ◽  
Perna Canaliculus ◽  
Liver Transaminases ◽  
Supplementary Treatment ◽  
Anti Inflammatory

Lyprinol, the lipid extract of the green-lipped mussel (Perna canaliculus), is a readily and freely available agent with a putative anti-inflammatory impact. It has already found application as a complementary and supplementary treatment of osteoarthritis, rheumatoid arthritis, asthma, and cancer. So far no major side effects for Lyprinol have been reported, yet. Here, we present the case of a 76-year-old woman with acutely exacerbating abdominal pain and highly elevated liver transaminases while taking Lyprinol as a complementary treatment of polyarthrosis.

scholarly journals Pain Controlling and Cytokine-Regulating Effects of Lyprinol, a Lipid Extract ofPerna canaliculus, in a Rat Adjuvant-Induced Arthritis Model

2009 ◽  
Vol 6 (2) ◽  
pp. 239-245 ◽  
Author(s):  
Chi-Ho Lee ◽  
John Hon-Kei Lum ◽  
Curtise Kin-Cheung Ng ◽  
Janice McKay ◽  
Yoki Kwok-Chu Butt ◽  
...  
Keyword(s):  
Virgin Olive Oil ◽  
Extra Virgin Olive Oil ◽  
Similar Efficacy ◽  
Lipid Extract ◽  
Perna Canaliculus ◽  
Adjuvant Induced Arthritis ◽  
Pain Scores ◽  
Tnf Α ◽  
Control Pain

Using an adjuvant-induced arthritis rat model, we investigated the effects of a lipid extract ofPerna canaliculus(Lyprinol®) on pain. Radiological examinations, as well as levels of pro- and anti-inflammatory (AI) cytokines, were measured aiming to provide independent objective data to the pain controlling investigation. We confirmed the ability of Lyprinol® to control pain at the initial phase of its administration; with similar efficacy to that observed with Naproxen. The pain scores slowly increased again in the group of rats treated with Lyprinol® after day 9–14. The Naproxen-treated rats remained pain-free while treated. Both Naproxen and Lyprinol® decreased the levels of the pro-inflammatory cytokines TNF-α and IFN-γ, and increased that of IL-10. Extra-virgin olive oil was ineffective on cytokine secretion. Rats treated with Lyprinol® were apparently cured after 1 year. This study confirms the AI efficacy of this lipid extract ofP. canaliculus, its initial analgesic effect, its perfect tolerance and its long-term healing properties.

scholarly journals Green-lipped (greenshell™) mussel (Perna canaliculus) extract supplementation in treatment of osteoarthritis: a systematic review

2021 ◽  
Author(s):  
Maryam Abshirini ◽  
Jane Coad ◽  
Frances M. Wolber ◽  
Pamela von Hurst ◽  
Matthew R. Miller ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Pain Relief ◽  
Treatment Effects ◽  
Gastrointestinal Symptoms ◽  
Lipid Extract ◽  
Current Evidence ◽  
Forest Plot ◽  
Significant Treatment ◽  
Perna Canaliculus

Abstract Objectives Intervention studies using New Zealand green-lipped or greenshell™ mussel (GSM) (Perna canaliculus) extract in osteoarthritis (OA) patients have shown effective pain relief. This systematic review summarises the efficacy of GSM extracts in the treatment of OA. Methods A literature search of the three databases EMBASE, MEDLINE, and Scopus was performed to identify relevant articles published up to March 2020. Inclusion criteria were clinical trials published in English measuring the effect of supplementation of whole or a lipid extract from GSM on pain and mobility outcomes in OA patients. Results A total of nine clinical trials were included in systematic review, from which five studies were considered appropriate for inclusion in a forest plot. Pooled results showed that GSM extracts (lipid extract or whole powder) provide moderate and clinically significant treatment effects on a visual analogue scale (VAS) pain score (effect size: − 0.46; 95% CI − 0.82 to − 0.10; p = 0.01). The whole GSM extract improved gastrointestinal symptoms in OA patients taking anti-inflammatory medications. The GSM extract was considered to be generally well tolerated in most of the studies. Conclusion The overall analysis showed that GSM provided moderate and clinically meaningful treatment effects on OA pain. However, the current evidence is limited by the number and quality of studies, and further larger and high-quality studies are needed to confirm the effectiveness and to identify the optimal GSM format. Nevertheless, it is worth considering using GSM extracts especially for patients seeking alternative pain relief treatments with fewer side effects compared to conventional treatment.

Treatment of acute hepatitis C infection with interferon-alfa 2b monotherapy prevents development of chronic HCV infection

2001 ◽  
Vol 120 (5) ◽  
pp. A567-A567 ◽  
Author(s):  
E JAECKEL ◽  
M CORNBERG ◽  
T SANTANTONIO ◽  
J MAYER ◽  
H WEDEMEYER ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Acute Hepatitis ◽  
Interferon Alfa ◽  
Hcv Infection ◽  
Acute Hepatitis C ◽  
Hepatitis C Infection ◽  
Chronic Hcv Infection ◽  
Chronic Hcv
Sign in / Sign up

Export Citation Format

Share Document