scholarly journals Enzyme-Free Electrochemical Glucose Sensors Prepared by Dealloying Pd-Ni-P Metallic Glasses

2014 ◽  
Vol 2014 ◽  
pp. 1-6
Author(s):  
Yuqiao Zeng ◽  
Hua Xiang ◽  
Chunlei Yang ◽  
Shengchen Yang ◽  
Luyang Chen ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Metallic Glasses ◽  
Glucose Sensor ◽  
Glucose Sensors ◽  
Chemical Compositions ◽  
Pore Sizes ◽  
Nanoporous Metals ◽  
Electrochemical Dealloying

We report the formation of enzyme-free electrochemical glucose sensors by electrochemical dealloying palladium-containing Pd-Ni-P metallic glasses. When metallic glasses with different Pd contents are used as the dealloying precursor alloys, palladium-based nanoporous metals with different ligament and pore sizes can be obtained. The chemical compositions of the nanoporous metals also vary according to the different precursor compositions. All the as-obtained nanoporous metals exhibit electrochemical catalytic activity towards the oxidation of d-glucose, indicating that the nanoporous metals prepared by dealloying the Pd-Ni-P metallic glasses are promising materials for enzyme-free electrochemical glucose sensor.

Low-voltage field-emission SEM of polymeric membranes for glucose biosensors

1990 ◽  
Vol 48 (3) ◽  
pp. 860-861
Author(s):  
Lorna K. Mayo ◽  
Kenneth C. Moore ◽  
Mark A. Arnold
Keyword(s):  
Glucose Sensor ◽  
Low Voltage ◽  
Glucose Sensors ◽  
Polymeric Membranes ◽  
Artificial Endocrine Pancreas ◽  
Self Monitoring ◽  
Conducting Materials ◽  
Insulin Dependent ◽  
Living Tissues ◽  
Voltage Scanning

An implantable artificial endocrine pancreas consisting of a glucose sensor and a closed-loop insulin delivery system could potentially replace the need for glucose self-monitoring and regulation among insulin dependent diabetics. Achieving such a break through largely depends on the development of an appropriate, biocompatible membrane for the sensor. Biocompatibility is crucial since changes in the glucose sensors membrane resulting from attack by orinter action with living tissues can interfere with sensor reliability and accuracy. If such interactions can be understood, however, compensations can be made for their effects. Current polymer technology offers several possible membranes that meet the unique chemical dynamics required of a glucose sensor. Two of the most promising polymer membranes are polytetrafluoroethylene (PTFE) and silicone (Si). Low-voltage scanning electron microscopy, which is an excellent technique for characterizing a variety of polymeric and non-conducting materials, 27 was applied to the examination of experimental sensor membranes.

One-step synthesis of novel Cu@polymer nanocomposites through a self-activated route and their application as nonenzymatic glucose sensors

2017 ◽  
Vol 46 (30) ◽  
pp. 9918-9924 ◽  
Author(s):  
Yinlin Tong ◽  
Jiaying Xu ◽  
Hong Jiang ◽  
Feng Gao ◽  
Qingyi Lu
Keyword(s):  
Polymer Nanocomposites ◽  
Glucose Sensor ◽  
Glucose Sensors ◽  
Core Shell ◽  
Nonenzymatic Glucose Sensor ◽  
One Step

Novel core–shell Cu@polymer nanocomposites were synthesized through a one-step self-activated route and developed as nonenzymatic glucose sensor.

Cuprous Oxide Films with Hollow Cubic Cage Structure for Nonenzymatic Glucose Detection

NANO ◽  
2019 ◽  
Vol 14 (04) ◽  
pp. 1950045
Author(s):  
Fang Sun ◽  
Lehong Xing ◽  
Xihui Yang ◽  
Hailiang Huang ◽  
Lina Ning
Keyword(s):  
Electrode Materials ◽  
Glucose Sensor ◽  
High Sensitivity ◽  
Fast Response ◽  
Glucose Sensing ◽  
Glucose Sensors ◽  
Cage Structure ◽  
Active Materials ◽  
Nonenzymatic Glucose Sensor ◽  
Step Procedure

In this study, CuO films with hollow cubic cages were prepared by a facile two-step procedure consisting of electrodeposition synthesis and subsequent direct calcination. First, Cu2O nanocubes were fabricated on ITO substrate through a simple electrodeposition procedure. Then, Cu2O nanocubes were converted to CuO hollow cubic cages without obvious morphological change through direct calcination. The obtained CuO cubic cages serving as active materials illustrated a favorable performance for nonenzymatic glucose sensing with high sensitivity of [Formula: see text]A[Formula: see text]mM[Formula: see text][Formula: see text]cm[Formula: see text] at a low applied potential of 0.50[Formula: see text]V, fast-response time (less than 3[Formula: see text]s), low detection limit of 1.0[Formula: see text][Formula: see text]M and wide linear range up from 2.0[Formula: see text][Formula: see text]M to 1.0[Formula: see text]mM ([Formula: see text]). Moreover, the good selectivity of the CuO cubic cages-based nonenzymatic glucose sensor against electroactive compounds such as ascorbic acid, uric acid and dopamine were also demonstrated. These good features indicate that the as-prepared CuO cubic cages can be used as promising electrode materials, which have a great potential in the development of sensitive and selective nonenzymatic glucose sensors.

scholarly journals Electrochemically Activated Conductive Ni-Based MOFs for Non-enzymatic Sensors Toward Long-Term Glucose Monitoring

2020 ◽  
Vol 8 ◽  
Author(s):  
Yating Chen ◽  
Yulan Tian ◽  
Ping Zhu ◽  
Liping Du ◽  
Wei Chen ◽  
...  
Keyword(s):  
Continuous Glucose Monitoring ◽  
Glucose Sensor ◽  
Glucose Monitoring ◽  
Glucose Sensors ◽  
Blood Glucose Monitoring ◽  
Diabetic Patients ◽  
Potential Range ◽  
Potential Applications ◽  
Naoh Solution

Continuous intensive monitoring of glucose is one of the most important approaches in recovering the quality of life of diabetic patients. One challenge for electrochemical enzymatic glucose sensors is their short lifespan for continuous glucose monitoring. Therefore, it is of great significance to develop non-enzymatic glucose sensors as an alternative approach for long-term glucose monitoring. This study presented a highly sensitive and selective electrochemical non-enzymatic glucose sensor using the electrochemically activated conductive Ni3(2,3,6,7,10,11-hexaiminotriphenylene)2 MOFs as sensing materials. The morphology and structure of the MOFs were investigated by scanning SEM and FTIR, respectively. The performance of the activated electrode toward the electrooxidation of glucose in alkaline solution was evaluated with cyclic voltammetry technology in the potential range from 0.2 V to 0.6 V. The electrochemical activated Ni-MOFs exhibited obvious anodic (0.46 V) and cathodic peaks (0.37 V) in the 0.1 M NaOH solution due to the Ni(II)/Ni(III) transfer. A linear relationship between the glucose concentrations (ranging from 0 to 10 mM) and anodic peak currents with R2 = 0.954 was obtained. It was found that the diffusion of glucose was the limiting step in the electrochemical reaction. The sensor exhibited good selectivity toward glucose in the presence of 10-folds uric acid and ascorbic acid. Moreover, this sensor showed good long-term stability for continuous glucose monitoring. The good selectivity, stability, and rapid response of this sensor suggests that it could have potential applications in long-term non-enzymatic blood glucose monitoring.

scholarly journals Rgt1p of Saccharomyces cerevisiae, a key regulator of glucose-induced genes, is both an activator and a repressor of transcription.

1996 ◽  
Vol 16 (11) ◽  
pp. 6419-6426 ◽  
Author(s):  
S Ozcan ◽  
T Leong ◽  
M Johnston
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Glucose Transporter ◽  
Glucose Sensor ◽  
Glucose Sensors ◽  
Hexose Transporter ◽  
Glucose Signaling ◽  
Low Glucose ◽  
Induced Genes ◽  
Low Levels ◽  
High Concentrations

The RGT1 gene of Saccharomyces cerevisiae plays a central role in the glucose-induced expression of hexose transporter (HXT) genes. Genetic evidence suggests that it encodes a repressor of the HXT genes whose function is inhibited by glucose. Here, we report the isolation of RGT1 and demonstrate that it encodes a bifunctional transcription factor. Rgt1p displays three different transcriptional modes in response to glucose: (i) in the absence of glucose, it functions as a transcriptional repressor; (ii) high concentrations of glucose cause it to function as a transcriptional activator; and (iii) in cells growing on low levels of glucose, Rgt1p has a neutral role, neither repressing nor activating transcription. Glucose alters Rgt1p function through a pathway that includes two glucose sensors, Snf3p and Rgt2p, and Grr1p. The glucose transporter Snf3p, which appears to be a low-glucose sensor, is required for inhibition of Rgt1p repressor function by low levels of glucose. Rgt2p, a glucose transporter that functions as a high-glucose sensor, is required for conversion of Rgt1p into an activator by high levels of glucose. Grr1p, a component of the glucose signaling pathway, is required both for inactivation of Rgt1p repressor function by low levels of glucose and for conversion of Rgt1p into an activator at high levels of glucose. Thus, signals generated by two different glucose sensors act through Grr1p to determine Rgt1p function.

Affinity Viscosimetry Sensor for Enzyme Free Detection of Glucose in a Micro-Bioreaction Chamber

2016 ◽  
Vol 879 ◽  
pp. 1135-1140
Author(s):  
Thilo Liebscher ◽  
Franziska Glös ◽  
Andrea Böhme ◽  
M. Birkholz ◽  
M. di Vona ◽  
...  
Keyword(s):  
Glucose Concentration ◽  
Glucose Sensor ◽  
Time Measurement ◽  
Glucose Sensors ◽  
Cell Cultivation ◽  
New Approach ◽  
Microelectromechanical System ◽  
Long Time ◽  
Free Glucose

With the growing demand of miniaturization of cell cultivation a new approach towards measuring and sensing bio-analytes needs to be made due to the problem of small volumes (less than 150μl) containing small amounts of analytes. Most of the available glucose sensors monitor the glucose concentration with the help of enzymes, which become very inaccurate in terms of long time measurement and uses (i.e. consumes) glucose during the measurement becoming not available anymore for the cells. Therefore, we focused on applying an enzyme-free glucose sensor based on a microelectromechanical system (MEMS).

scholarly journals A Study of the Catalytic Properties of Synthetic Aluminosilicates of Different Morphologies in Cracking Reactions of the Byproducts of Isoprene Synthesis

2021 ◽  
Vol 47 (5) ◽  
pp. 469-480
Author(s):  
Yu. A. Alikina ◽  
E. A. Spetsov ◽  
N. Yu. Ulyanova ◽  
O. Yu. Golubeva
Keyword(s):  
Catalytic Activity ◽  
Aluminum Oxide ◽  
Specific Surface ◽  
Surface Area ◽  
Catalytic Properties ◽  
Raw Materials ◽  
Layered Silicates ◽  
Chemical Compositions ◽  
Cyclic Compounds ◽  
Isoprene Synthesis

Abstract The catalytic activity of synthetic samples of aluminosilicates of various morphologies and chemical compositions in a cascade of reactions that are byproducts (BPs) in the decomposition process of 4,4‑dimethyl-1,3-dioxane is studied. Aluminosilicates with montmorillonite structures (Na0.2Al1.8Mg0.2Si4O10(OH)2⋅nH2O, Mg3Si4O10(OH)2⋅nH2O), and kaolinite (Al2Si2O5(OH)4) with the spherical and platy morphologies of particles, as well as their porous-textural characteristics and surface properties, are studied. It is shown that the specific surface area of the studied samples, depending on the composition, varies from 11 to 470 m2/g, and the content of aluminum oxide in the samples ranged from 0 to 24 wt %. It is found that layered silicates with a montmorillonite structure contribute to reducing the gasification of organic raw materials and increasing the yield of isoprene. Kaolinite with a spherical morphology of particles increases the yield of formaldehyde, and with a platy morphology of particles, it increases the degree of decomposition of heteroatomic and cyclic compounds.

Influence of Substituting Al by Mg-Co and Mn-Co on the Properties of AlPO4-5

1992 ◽  
Vol 57 (4) ◽  
pp. 750-755 ◽  
Author(s):  
Liao Changsheng
Keyword(s):  
Catalytic Activity ◽  
Infrared Spectra ◽  
Molecular Sieves ◽  
Molecular Sieve ◽  
Surface Acidity ◽  
Chemical Compositions ◽  
Hydrothermal Crystallization ◽  
X Ray Diffraction ◽  
X Ray ◽  
Crystallization Method

Two kinds of crystalline microporous metal aluminophosphate molecular sieves, magnesium cobalt aluminophosphate (MgCoAPO-5) and manganese cobalt aluminophosphate (MnCoAPO-5), were synthesized by hydrothermal crystallization method in order to improve the surface acidity and catalytic activity of AlPO4-5. The results of X-ray diffraction, infrared spectra and chemical compositions of MgCoAPO-5 and MnCoAPO-5 indicate that Mg-Co or Mn-Co enter the framework of AlPO4-5 molecular sieve without disrupting the microporous framework. However, the results of catalytic studies show that MgCoAPO-5 and MnCoAPO-5 possess much higher surface acidity and catalytic activity than the unmodified AlPO4-5.

scholarly journals A non-enzymatic glucose sensor based on electrospun 3-D copper oxide micro-nanofiber network films using carboxylic-functionalized poly(arylene ether ketone)s as templates

RSC Advances ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 6613-6619 ◽  
Author(s):  
Mengzhu Liu ◽  
Yongpeng Wang ◽  
Haibo Zhang ◽  
Zhenhua Jiang
Keyword(s):  
Copper Oxide ◽  
Electrode Material ◽  
Glucose Sensor ◽  
High Surface ◽  
Volume Ratio ◽  
Glucose Sensors ◽  
Arylene Ether ◽  
Ether Ketone ◽  
Promising Electrode Material

3-D network films of rope-like CuO-MNFs with high surface-to-volume ratio were prepared. The product is a promising electrode material for fabrication of amperometric enzymeless glucose sensors.

Sign in / Sign up

Export Citation Format

Share Document