scholarly journals Tolerance to Systemic Isotretinoin Therapy in Two Patients Using Highly Wettable Contact Lenses

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Ayşegül Arman ◽  
D. Deniz Demirseren ◽  
Gulsen Akoglu
Keyword(s):  
Contact Lens ◽  
Ocular Surface ◽  
Contact Lenses ◽  
Tear Film ◽  
Film Stability ◽  
Function Tests ◽  
Tear Film Stability ◽  
Retinoid Therapy ◽  
Isotretinoin Therapy ◽  
Tear Film Function

Purpose.Numerous ocular side effects have been reported with the use of systemic isotretinoin therapy. Herein, we presented two contact lens user patients who did not have contact lens intolerance during systemic isotretinoin therapy.Methods.25-year-old male and 20-year-old female patients with severe acne vulgaris who were using highly wettable silicone hydrogel contact lenses which increase tear film stability were examined. Tear film function tests including Schirmer tests and tear break up time (TBUT) test and ocular surface staining with fluorescein were done. Subjective ocular complaints were scored with ocular surface disease index (OSDI) questionnaire. Patients were followed up monthly and examinations were repeated at each visit.Results.Both patients completed the therapy after a cumulative dose of 140 mg/kg isotretinoin in 6 months. The OSDI score and tear film function tests before and after treatment were all within normal limits.Discussion.Highly wettable contact lenses that provide increase in the tear film stability may be used during systemic retinoid therapy under close followups. Although isotretinoin affects ocular glands, the differences between tolerances to this retinoid therapy need to be investigated in larger patient groups using contact lenses.

scholarly journals Association Between Ocular Surface Temperature and Tear Film Stability in Soft Contact Lens Wearers

2018 ◽  
Vol 59 (2) ◽  
pp. 771 ◽  
Author(s):  
Takashi Itokawa ◽  
Yukinobu Okajima ◽  
Takashi Suzuki ◽  
Koji Kakisu ◽  
Hiroko Iwashita ◽  
...  
Keyword(s):  
Surface Temperature ◽  
Contact Lens ◽  
Ocular Surface ◽  
Tear Film ◽  
Soft Contact ◽  
Film Stability ◽  
Soft Contact Lens ◽  
Tear Film Stability

Analysis of visual function and tear film stability in contact lens wearers with one-day disposable contact lenses

2015 ◽  
Vol 38 ◽  
pp. e29-e30 ◽  
Author(s):  
Maria Gonzalez-Garcia ◽  
Alberto Lopez-de-la-Rosa ◽  
Vicente Martin ◽  
Jose Pinto ◽  
Antonio Abengozar ◽  
...  
Keyword(s):  
Contact Lens ◽  
Visual Function ◽  
Contact Lenses ◽  
Tear Film ◽  
Film Stability ◽  
Tear Film Stability

scholarly journals Association among Blink Rate, Changes in Ocular Surface Temperature, Tear Film Stability, and Functional Visual Acuity in Patients after Cataract Surgery

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Takashi Itokawa ◽  
Yukinobu Okajima ◽  
Takashi Suzuki ◽  
Tatsuhiko Kobayashi ◽  
Yuto Tei ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Regression Analysis ◽  
Cataract Surgery ◽  
Ocular Surface ◽  
Tear Film ◽  
Blink Rate ◽  
Film Stability ◽  
Tear Film Stability ◽  
Functional Visual Acuity ◽  
Film Group

Purpose. To investigate the association among the ocular surface temperature (OST), tear film stability, functional visual acuity (FVA), and blink rate in patients after cataract surgery. Methods. We recruited 98 eyes of 69 patients (mean age, 73.7 ± 5.2 years) 1 month after phacoemulsification with implantation of acrylic intraocular lenses and assessed slit-lamp microscopy, corrected distance VA, FVA, noninvasive tear breakup time (NIBUT), and OST. We defined the changes in the OST from 0 to 10 seconds after eye opening as the ΔOST. We measured the FVA and blink rate using the FVA measurement system. We divided the patients into two groups based on tear film stability: stable tear film (NIBUT, >5.0 seconds) and unstable tear film (NIBUT, ≤5.0 seconds). We evaluated the differences between the two groups and the association between the blink rate and other clinical parameters. Results. The unstable tear film group (56 eyes) had significantly (p<0.0001, unpaired t-test) shorter NIBUTs than the stable tear film group (42 eyes). The ΔOSTs and blink rates were significantly (p<0.0001) higher in the unstable tear film group than in the stable group. Linear single regression analysis showed that the ΔOST (r = −0.430, p<0.0001), NIBUT (r = −0.392, p<0.0001), and gender (r = −0.370, p=0.0002) were correlated significantly with the blink rate. Multiple regression analysis showed that the ΔOST independently contributed to the blink rate. Conclusions. The frequency of blinks is associated with tear film stability in patients after cataract surgery. The blink rate may be useful for evaluating the tear film stability in clinical practice. The ΔOST should be an important contributing factor to the blink rate. [This trial is registered with UMIN000026970].

The ocular surface in children: A review of current knowledge and meta-analysis of tear film stability and tear secretion in children

2019 ◽  
Vol 17 (1) ◽  
pp. 28-39 ◽  
Author(s):  
Ngozi Charity Chidi-Egboka ◽  
Nancy E. Briggs ◽  
Isabelle Jalbert ◽  
Blanka Golebiowski
Keyword(s):  
Ocular Surface ◽  
Current Knowledge ◽  
Meta Analysis ◽  
Tear Film ◽  
Film Stability ◽  
Tear Secretion ◽  
Tear Film Stability

Clinical manifestations of the dry eye syndrome for women in menopause

2014 ◽  
Vol 5 (2) ◽  
pp. 25-29
Author(s):  
Nataliya Nikolayevna Sadovnikova ◽  
Galiya Fettyakhovna Kutusheva
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Clinical Manifestations ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Menopausal Syndrome ◽  
Film Stability ◽  
Tear Film Stability ◽  
Functional Features ◽  
Subjective Discomfort

To assess the effect of menopausal syndrome manifestations in the manifestation of «dry eye» examined 63 women . All examined the condition of the ocular surface, tear film stability, severity of subjective discomfort . Revealed that the dry eye syndrome in postmenopausal women occurs predominantly in the mild and moderate forms, with the severity of clinical and functional features of dry eye syndrome significantly correlated with severity of menopausal symptoms .

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