Clinical manifestations of the dry eye syndrome for women in menopause

2014 ◽  
Vol 5 (2) ◽  
pp. 25-29
Author(s):  
Nataliya Nikolayevna Sadovnikova ◽  
Galiya Fettyakhovna Kutusheva
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Clinical Manifestations ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Menopausal Syndrome ◽  
Film Stability ◽  
Tear Film Stability ◽  
Functional Features ◽  
Subjective Discomfort

To assess the effect of menopausal syndrome manifestations in the manifestation of «dry eye» examined 63 women . All examined the condition of the ocular surface, tear film stability, severity of subjective discomfort . Revealed that the dry eye syndrome in postmenopausal women occurs predominantly in the mild and moderate forms, with the severity of clinical and functional features of dry eye syndrome significantly correlated with severity of menopausal symptoms .

scholarly journals Correlation of vitamin D levels with tear film stability and secretion in patients with dry eye syndrome

2016 ◽  
Vol 95 (3) ◽  
pp. e230-e235 ◽  
Author(s):  
Ki Won Jin ◽  
Jin Woo Ro ◽  
Young Joo Shin ◽  
Joon Young Hyon ◽  
Won Ryang Wee ◽  
...  
Keyword(s):  
Vitamin D ◽  
Dry Eye ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Film Stability ◽  
Vitamin D Levels ◽  
Tear Film Stability

Choosing the optimal method for preoperative risk assessment of dry eye syndrome development in patients with myopia

Reflection ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 30-36
Author(s):  
O.V. Kolenko ◽  
◽  
Y.V. Kutuzova ◽  
I.V. Dutchin ◽  
E.L. Sorokin ◽  
...  
Keyword(s):  
Dry Eye ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Rupture Time ◽  
Film Rupture ◽  
Optimal Method ◽  
Film Stability ◽  
Tear Film Stability ◽  
Keratorefractive Surgery ◽  
The Stability

Aim. Comparative analysis of the effectiveness of keratotopography methods and classical Norn’s test in assessing the stability of the tear film (TF) in patients with myopia before photorefractive surgery. Methods. The study involved 26 patients. All of them were planned for keratorefractive surgery to correct myopic refraction and astigmatism. Their age averaged 32.5±14.5 years (18-47 years). The stability of pre-corneal tear film was assessed using computed keratotopography and Norn’s test - the tear film rupture time (TFRT) was determined. A standard questionnaire was also used to assess the severity of symptoms of dry eye syndrome (DES). A comparison was made of the indicators of tear film, stability obtained by the methods of keratotopography and Norn’s test, with their subsequent comparison with the data of the questionnaire. Results. In 17 patients (65.4 %), TFRT index corresponded to the age norm. In the remaining 9 people (34.6 %), indicators of tear film stability were reduced both by keratotopography (12±4 sec) and by Norn’s test (13.5± 4.5 sec), and there were also subjective signs of dry eye syndrome according to questionnaire data. The data turned out to be comparable. Conclusion. The incidence of impaired stability of the TF and subjective manifestations of DES among patients planned for keratorefractive surgery for myopia and myopic astigmatism was significant and, according to our data, made 34.6 %. To prevent complicated postoperative course of photorefractive surgery, it is necessary to assess the condition of the ocular surface immediately before refractive surgery, to identify the risk group for DES development. Key words: dry eye syndrome; tear film; keratotopography; Norn’s test; tear film rupture time.

scholarly journals Dry Eye Syndrome in Glaucomatous Patients using Topical Anti-Glaucoma Therapy

2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Nabila Zulfiqar ◽  
Muhammad Sufyan Aneeq Ansari ◽  
Khurram Nafees ◽  
Rabia Nawaz ◽  
Manzra Shaheen
Keyword(s):  
Observational Study ◽  
Study Design ◽  
Dry Eye ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Film Stability ◽  
Glaucoma Therapy ◽  
Tear Film Stability ◽  
Time Test ◽  
Break Up

Purpose:  To determine the frequency of Dry eye in Glaucoma patients using topical anti-glaucoma therapy. Study Design:  Descriptive Observational study. Place and Duration of Study:  Study was conducted in outpatient department of Fatima Memorial Hospital Shadman, Lahore, from October 2016 to February 2017. Material & Methods:  In this study, 61 diagnosed cases of glaucoma were included. Patients with significant dermatological problems that may be associated with dry eye such as rosacea and blepharitis were excluded from the study. The individuals were assessed by consultant Ophthalmologist for Dry eye syndrome having symptoms of stinging and burning sensations itching, watering, irritation, due to regular use of topical anti-glaucoma drugs. A written consent was taken from every patient before the test. The ocular surfaces of the patients were evaluated using Tear film break-up time test and Basal Schrimer’s test. Patients having TBUT less than 11 seconds were categorized as having dry eye. The degree of dryness was categorized as mild, moderate and sever Dry eye. Results:  Among 61 patients of glaucoma using topical anti-glaucoma therapy, 22 (36.1%) were male and 39 (63.9%) were female. Mean age of the patients was 50.76 ± 15.67 years. On the basis of Tear film Break-up time test, 49 (81%) patients had Tear Break-up time less than 10 seconds and 12 (19%) patients were normal. On the basis of Schrimer`s test 51 (83.66%) patients had Dry eye. Conclusion:  Topical use of anti-glaucoma therapy affects tear film stability and its functions leading to Dry eye syndrome.

scholarly journals Compliance as an Integral Part of the Dry Eye Syndrome Prevention Using Silicone Hydrogel Contact Lenses

2016 ◽  
Vol 23 (4) ◽  
pp. 201647
Author(s):  
Rimma Skrypnyk ◽  
Olga Selezneva
Keyword(s):  
Dry Eye ◽  
Contact Lenses ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Film Stability ◽  
Silicone Hydrogel ◽  
Clinical Guidance ◽  
Schirmer’S Test ◽  
Group I ◽  
Tear Film Stability

The probability of dry eye syndrome (DES) in the patients using the Silicone-Hydrogel Contact Lenses is examined in many researches. Therefore, adhering to clinical recommendations is an important factor for DES prevention. The urgent issue is also a comprehensive assessment of functional parameters as pathogenetic base of DES.The objective of the research was tostudy DES development depending on compliance of silicone hydrogel contact lenses users.Matherials and methods. 97 patients (194 eyes) were included into the research. They formed 2 groups: group I with incomplete compliance (36 persons) and group II with complete compliance (61 persons). All the patients underwent the Norn’s test, Schirmer’s test, Jones test, tear film stability was defined. The probability of the dry eye syndrome development due to the subjective signs was also analysed.Results. The reliable decrease in the total (р<0.05) and basale lacrimation (р<0.05) indexes, the increase in osmolarity (р<0.05) and decrease in tear film stability (р<0.05) were detected in the patients who did not follow the clinical guidance during the Silicone-Hydrogel Contact Lenses wearing. In the same group the higher risk of dry eye syndrome development was verified (р<0.05).Conclusion. Compliance disorder in the patients using Silicone-Hydrogel Contact Lenses was found to induce the reliable decrease in total and basale lacrimation, increase in osmolarity and tear stability disorder. All of this factors increase the risk of dry eye syndrome.

scholarly journals New Possibilities of Tear Replacement Therapy in Patients with Dry Eye Syndrome of Various Origins

2019 ◽  
Vol 16 (2) ◽  
pp. 244-251
Author(s):  
V. V. Brzheskiy ◽  
S. Yu. Golubev ◽  
I. V. Brzheskaya ◽  
V. Yu. Popov
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Sodium Hyaluronate ◽  
Tear Film ◽  
Severe Form ◽  
Dry Eye Syndrome ◽  
Degenerative Changes ◽  
Ocular Surface Disease Index ◽  
Film Stability ◽  
Days Of Therapy

The artificial tears on the basis hyaluronic acid is primary importance today in dry eye syndrome (DES) treatment. In recent years, they have been supplemented Optinol® Express Moisture (0.21 %) and Optinol® Deep Moisture (0.4 %) differing concentrations of sodium hyaluronate and viscosity. The study is devoted to assessing the effectiveness of these drugs in the treatment of patients with dry eye syndrome (DES) of various etiology and severities.There were 73 volunteers with DES of various etiology: 21 — Sjogren’s syndrome, 24 — meibomian blepharitis, and 28 — perimenopause in the study. All patients were divided into 2 groups: 36 patients of the first group received instillations into conjunctival cavity of the Optinol® Express Moisture (0.21 %) and 37 patients of the second group — Optinol® Deep moistening (0.4 %).Starting from the first days of therapy, all patients had a decrease in the severity of subjective signs of DES, estimated by the value of the ocular surface disease index (OSDI). At the same time, tendency to stop of the degenerative changes in the epithelium of the ocular surface was established. It is characterized by a decrease in the degree of staining. The increasement of the tear film stability and an index of the tear meniscus was found in all patients. The dynamics of the controlled parameters increased, as the instillation of the drugs took place and by the 30th day of therapy. There were significant differences from the baseline values. At the same time, the Optinol® Express Moisture (0.21 %) was more effective (mainly in terms of subjective discomfort and the severity of degenerative changes in the epithelium of the ocular surface) in patients with mild and extremely severe form of the xerosis process.The drug Optinol® Deep Moisture (0.4 %) was more effective in patients with xerosis of moderate severity and severe by the same parameters. In the course of research, we have not observed any side effects of both drugs. It allows us to recommend the drugs Optinol® Express Moisture (0.21 %) and Optinol® Deep Moisture (0.4 %) to widespread clinical use in treating patients with DES of various etiology. 

scholarly journals Peripheral Neuropathy and Tear Film Dysfunction in Type 1 Diabetes Mellitus

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Stuti L. Misra ◽  
Dipika V. Patel ◽  
Charles N. J. McGhee ◽  
Monika Pradhan ◽  
Dean Kilfoyle ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Peripheral Neuropathy ◽  
Dry Eye ◽  
Ocular Surface ◽  
Tear Film ◽  
Lipid Layer ◽  
Film Stability ◽  
Tear Film Stability

Purpose.To compare tear film metrics in patients with type 1 diabetes mellitus (DM) and healthy controls and investigate the association between peripheral neuropathy and ocular surface quality.Methods.Dry eye symptoms were quantified in 53 patients with type 1 DM and 40 age-matched controls. Ocular examination included tear film lipid layer thickness grading, tear film stability and quantity measurement, and retinal photography. DM individuals additionally underwent a detailed neuropathy assessment.Results.Neither mean age nor dry eye symptom scores differed significantly between the DM and control groups (P=0.12andP=0.33, resp.). Tear lipid thickness (P=0.02), stability (P<0.0001), and quantity (P=0.01) were significantly lower in the DM group. Corneal sensitivity was also reduced in the DM group (P<0.001) and tear film stability was inversely associated with total neuropathy score (r=-0.29,P=0.03).Conclusion.The DM group exhibited significantly reduced tear film stability, secretion, and lipid layer quality relative to the age-matched control group. The negative correlation between tear film parameters and total neuropathy score suggests that ocular surface abnormalities occur in parallel with diabetic peripheral neuropathy.

scholarly journals Changes in the functionality of tear film and autorefractometry reading after instillations of artificial tear products of different viscosity

2021 ◽  
Vol 21 (4) ◽  
pp. 200-204
Author(s):  
V.V. Brzheskiy ◽  
◽  
E.L. Efimova ◽  
M.A. Kopylova ◽  
P.V. Kocharina ◽  
...  
Keyword(s):  
Dry Eye ◽  
Sodium Hyaluronate ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Critical Parameters ◽  
Film Stability ◽  
Axis Orientation ◽  
Artificial Tear ◽  
Diagnostic Unit ◽  
Tear Film Stability

Aim: to study the changes in the critical parameters of tear film stability and autorefractometry in patients with mild dry eye syndrome (DES) after instilling artificial tear products of different viscosity. Patients and Methods: thirty patients aged 23–70 with mild bilateral DES were examined using the Visionix VX120+Dry Eye multi-diagnostic unit equipped with the TF-Scan to fix and assess tear film stability and tear breakup time (TBUT). The critical refraction and tear film parameters were evaluated by keratometry, corneal topography, TBUT, and tear meniscus height measurements. Next, an artificial tear product was instilled, i.e., group 1 (14 patients, 28 eyes) received a 0.15% sodium hyaluronate-based preparation, and group 2 (16 patients, 32 eyes) received a 0.4% sodium hyaluronate-based preparation. The examination was repeated after 30 sec and 5 min. Controls were seven healthy individuals (14 eyes). Results: in DES, breaks in the tear film appeared earlier and affected greater corneal surface area. A "Destabilized tear film area" parameter of the Visionix VX120+Dry Eye contributed significantly to the knowledge of tear film functionality, thereby empowering the diagnostic armamentarium in DES. As early as 30 sec after instillation of both artificial tear preparations, breakup-free time tended to increase, while the area of tear film destabilization tended to reduce. After 5 min, this trend continued to increase, particularly after instilling 0.15% sodium hyaluronate-based preparation. At the same time, changes in keratometry readings (i.e., sphere and cylinder) and astigmatism axis orientation were reported. Corneal refractive power (more in the flattest axis) increased, in particular, after the instillations of 0.15% hyaluronic acid. The range of changes was 0.00–0.75 D for the sphere power, 0.00–0.50 D for the cylinder power, and 0–69 degrees for astigmatism axis orientation. Conclusions: our findings with the Visionix VX120+Dry Eye multi-diagnostic unit demonstrate a significant variation of autorefractometry readings in DES depending on the extent of ocular surface hydration. These phenomena raise questions about the accuracy of autorefractometry readings. Therefore, autorefractometry should be performed after normalizing tear film volume and stability. Keywords: dry eye syndrome, Visionix®, autorefractometry, tearscopy, the effect of artificial tears on results. For citation: Brzheskiy V.V., Efimova E.L., Kopylova M.A. et al. Changes in the functionality of tear film and autorefractometry reading after instillations of artificial tear products of different viscosity. Russian Journal of Clinical Ophthalmology. 2021;21(4):200–204 (in Russ.). DOI: 10.32364/2311-7729-2021-21-4-200-204.

scholarly journals Current Concepts about the Etiology of Dry Eye Syndrome

2019 ◽  
Vol 16 (2) ◽  
pp. 236-243
Author(s):  
V. N. Trubilin ◽  
E. G. Polunina ◽  
D. V. Angelova ◽  
V. V. Kurenkov ◽  
S. G. Kapkova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Dry Eye ◽  
Ocular Surface ◽  
Clinical Manifestations ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Eye Drops ◽  
Ocular Surface Diseases ◽  
Pathophysiological Role ◽  
Botulinum Toxin Injections

The revolution in understanding the etiology and clinical manifestations of the disruption of the tearing process and the development of dry eye syndrome (CVS) has occurred in last 20–30 years. It has been established that the loss of the tear film homeostasis can occur not only because of a violation of systemic and autoimmune disorders, but also as a result of a blinking disorder and distribution of the tear film over the ocular surface. Therefore, new pathogenetic disease development mechanisms have been identified. The prevalence of diseases of the ocular surface and CVD in recent years has increased significantly. It is mostly caused not only by scientific discoveries in the field of understanding, for example, the etiological and pathophysiological role of the neurosensory mechanism of development of CVS. An important aspect is the emergence of new risk factors that potentiate the development of ocular surface diseases and CVL. These factors include the use of various drugs — antidepressants, antihistamines, hormone therapy, and others; instillation of eye drops — antiglaucoma drugs, etc., as well as the appearance of little-studied factors such as cosmetology procedures (eyelids tattooing, eyelash extensions, botulinum toxin injections for aesthetic purposes, etc.). They are carried out in proximate close to the eye and eyelids, causing multiple pathological reaction. The experience of observing patients, literature data, and the conducted study have showed that various cosmetological effects in the periorbital zone, whose popularity has increased in recent years, may cause the appearance of iatrogenic dry eye syndrome. The following most vivid clinical examples will help, encountered in our practice, to illustrate the data presented. Collecting the anamnesis, it is necessary to identify the presence of risk factors for the development of diseases of the ocular surface and CVD, to eliminate them, if possible, and to carry out adequate pathogenically based therapy.

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