scholarly journals Osseous Choristoma of the Tongue: A Review of Etiopathogenesis

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Edoardo Gorini ◽  
Mauro Mullace ◽  
Luca Migliorini ◽  
Emilio Mevio
Keyword(s):  
Bone Tissue ◽  
Surgical Excision ◽  
Definitive Diagnosis ◽  
Histopathologic Examination ◽  
Review Of The Literature ◽  
Oral Region ◽  
Normal Bone ◽  
Normal Bone Tissue

Osseous choristoma is a normal bone tissue in an ectopic position. In the oral region lingual localization occurs more frequently and the mass is generally localized on the dorsum of the tongue. Definitive diagnosis is obtained only after histopathologic examination. The etiology remains already debatable. The treatment of choice is surgical excision. In this paper we present a case of tongue osseous choristoma and a review of the literature.

scholarly journals Ossifying Fibroma of the Maxilla: A Case Report and Literature Update

2021 ◽  
pp. 1-4
Author(s):  
Abdouldaim Ukwas ◽  
Abdouldaim Ukwas ◽  
Mohammed Magdy ◽  
Mahmoud Elshik
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Bone Grafting ◽  
Fibrous Tissue ◽  
Definitive Diagnosis ◽  
Ossifying Fibroma ◽  
Normal Bone ◽  
Calcified Tissues ◽  
Slow Growing ◽  
Normal Bone Tissue

Ossifying fibroma is a rare benign fibro-osseous neoplasm of the jaw characterized by the replacement of normal bone tissue by a combination of fibrous tissue and newly formed calcified tissues of bone and/or cementum-like material. Lesions often manifest at the 2nd to 4th decades of life with a predominant female predilection. The tumor is usually slow-growing and asymptomatic but can cause notable expansion of the jawbones. Definitive diagnosis of OF can be challenging and usually requires careful clinical, radiographic and histologic assessments. Treatment commonly depends on the size, location and aggressiveness of tumor and can accordingly vary from enucleation and curettage to resection and bone grafting. The prognosis is generally good when the lesion is completely removed, but recurrence is possible in some circumstances. The aim of this article is to present a case report of a recurrent ossifying fibroma in a 28-year-old female patient and to provide an update of the literature.

scholarly journals Genes associated with inflammation and bone remodeling are highly expressed in the bone of patients with the early-stage cam-type femoroacetabular impingement

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Guanying Gao ◽  
Ruiqi Wu ◽  
Rongge Liu ◽  
Jianquan Wang ◽  
Yingfang Ao ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bone Tissue ◽  
Bone Remodeling ◽  
Femoroacetabular Impingement ◽  
Early Stage ◽  
Control Group ◽  
Tissue Samples ◽  
Expression Levels ◽  
Normal Bone ◽  
Impingement Zone

Abstract Background Recent studies have shown high expression levels of certain inflammatory, anabolic, and catabolic genes in the articular cartilage from the impingement zone of the hips with femoroacetabular impingement (FAI), representing an increased metabolic state. Nevertheless, little is known about the molecular properties of bone tissue from the impingement zone of hips with FAI. Methods Bone tissue samples from patients with early-stage cam-type FAI were collected during hip arthroscopy for treatment of cam-type FAI. Control bone tissue samples were collected from six patients who underwent total hip replacement because of a femoral neck fracture. Quantitative real-time polymerase chain reaction (PCR) was performed to determine the gene expression associated with inflammation and bone remodeling. The differences in the gene expression in bone tissues from the patients with early-stage cam-type FAI were also evaluated based on clinical parameters. Results In all, 12 patients with early-stage cam-type FAI and six patients in the control group were included in this study. Compared to the control samples, the bone tissue samples from patients with FAI showed higher expression levels of interleukin-6 (IL-6), alkaline phosphatase (ALP), receptor activator of nuclear factor-kB ligand (RANKL), and osteoprotegerin (OPG) (P < 0.05). IL-1 expression was detected only in the control group. On the other hand, there was no significant difference in IL-8 expression between the patients with FAI and the control group. The patients with FAI having a body mass index (BMI) of >24 kg/m2 showed higher ALP expression (P < 0.05). Further, the expression of IL-6 and ALP was higher in the patients with FAI in whom the lateral center-edge angle was >30° (P < 0.05). Conclusions Our results indicated the metabolic condition of bone tissues in patients with early-stage cam-type FAI differed from that of normal bone in the femoral head-neck junction. The expression levels of the genes associated with inflammation and bone remodeling were higher in the bone tissue of patients with early-stage cam-type FAI than in the patients with normal bone tissue.

scholarly journals Nasal Epithelial Myoepithelial Carcinoma: An Unusual Cause of Epiphora, a Case Report and Review of the Literature

2015 ◽  
Vol 6 (2) ◽  
pp. ar.2015.6.0127 ◽  
Author(s):  
Juliette O. Flam ◽  
Christopher D. Brook ◽  
Rachel Sobel ◽  
John C. Lee ◽  
Michael P. Platt
Keyword(s):  
Case Report ◽  
Physical Examination ◽  
Nasal Cavity ◽  
Surgical Excision ◽  
Myoepithelial Carcinoma ◽  
Review Of The Literature ◽  
Nasal Symptoms ◽  
First Case ◽  
Nasal Tumor ◽  
Epithelial Myoepithelial Carcinoma

Introduction Epithelial myoepithelial carcinoma (EMC) of the nasal cavity is a rare tumor, and here we describe the first case of EMC of the nasal cavity presenting with epiphora. A case presentation and review of the literature is provided. Methods A case report is described of a 63-year-old man who presented with unilateral epiphora and was found via a thorough history and physical examination to have a nasal tumor. The physical examination consisted of an ocular examination, including probing and irrigation, and a detailed nasal examination (anterior rhinoscopy, nasal endoscopy). The nasal examination was prompted by the patient's report of concurrent nasal symptoms during history taking. Immunohistochemistry subsequently identified the nasal tumor as EMC. A literature search was performed to gain insights into similar malignancies of the nasal cavity. Results Eight cases of EMC of the nasal cavity were identified in the literature, none of the patients presented with epiphora. The case presented here resulted in resolution of the patient's symptoms and no evidence of disease after surgical excision. Conclusion Epithelial myoepithelial is a rare salivary gland malignancy that can arise in the nasal cavity. Unilateral epiphora with concurrent nasal symptoms should prompt nasal cavity examination for the possibility of an obstructive tumor.

POST-MANDIBULAR FRACTURE OSTEOMYELITIS: CASE REPORT AND LITERATURE REVIEW

2021 ◽  
Author(s):  
Murilo Mendes Dourado
Keyword(s):  
Antibiotic Therapy ◽  
Bone Tissue ◽  
Periodontal Diseases ◽  
Trauma Treatment ◽  
Facial Trauma ◽  
Review Of The Literature ◽  
Odontogenic Infections ◽  
Difficult Diagnosis ◽  
Mandible Fracture ◽  
Relevant Role

Osteomyelitis represents an inflammatory entity of the bone tissue with spinal cord involvement. Its etiology is multifactorial, presenting difficult diagnosis and complex treatment, being the prognosis, in most cases, unpredictable. Therefore, it is an inflammation of the medullary spaces caused by the decrease of the blood supply, leading to an ischemia and subsequent necrosis of the bone tissue. Although odontogenic infections are the most commonly involved in the onset of osteomyelitis, other situations also play a relevant role, such as: periodontal diseases, exodontia, and facial trauma. Treatment included combination of antibiotic therapy and surgical procedures. Although correct antibiotic therapy plays an important role in the success of the treatment, the surgical procedure is essential for the removal of the cause and possible bone sequestration formed by the infectious process. The objective of this work is to perform a review of the literature on Osteomyelitis and present two cases of Chronic Suppurative Osteomyelitis that emerged as a complication of mandible fracture. We observed that OSC caused after fracture of face presents clinical characteristics similar to those from odontogenic infection and that the treatment of choice is similar.

Metastases to the Pituitary Gland: Histological Patterns of Spread and Review of the Literature

2021 ◽  
Author(s):  
B K Kleinschmidt-DeMasters
Keyword(s):  
Pituitary Adenoma ◽  
Pituitary Gland ◽  
Surgical Excision ◽  
Disease Course ◽  
Review Of The Literature ◽  
Metastatic Cells ◽  
Filling Pattern ◽  
Pituitary Metastases ◽  
Atypical Pituitary Adenoma ◽  
Disease Stages

Abstract Few studies have focused on histological patterns of metastatic spread to the pituitary gland. We review our experience and that in the literature, 1970–present. Departmental cases, 1998–2021, were assessed for anterior versus posterior gland and/or capsular involvement and cohesive tumor obliterating underlying pituitary architecture versus metastatic cells filling pituitary acini with relative acinar preservation. Eleven autopsy/15 surgical cases, including 2 metastases to pituitary adenomas, were identified. Cohesive/obliterative patterns predominated histologically in both surgical and autopsy cases, but acinar filling by metastatic cells was extensive in 3/26 cases, focal in 5/26, and had resulted in initial erroneous impressions of atypical pituitary adenoma/pituitary carcinoma in 1 case and pituitary adenoma with apoplexy in another, likely due to focusing on necrotic areas in the specimen where the acinar pattern had been broken down and not appreciating nearby areas with acinar filling by metastatic cells. Although most pituitary metastases produce readily identifiable cohesive/obliterative patterns, diagnostic challenges remain with the less frequently seen “acinar filling” pattern. A dichotomy exists between patients with symptomatic pituitary metastases occurring early in the disease course and requiring surgical excision versus patients in whom asymptomatic small pituitary metastases are found incidentally at autopsy, the latter almost invariably in late disease stages, with widely disseminated metastatic disease.

Cutaneous Melanocytomas in 10 Young Cattle

1995 ◽  
Vol 32 (5) ◽  
pp. 479-484 ◽  
Author(s):  
M. A. Miller ◽  
A. D. Weaver ◽  
P. L. Stogsdill ◽  
J. R. Fischer ◽  
J. M. Kreeger ◽  
...  
Keyword(s):  
Coat Color ◽  
Surgical Excision ◽  
Histopathologic Examination ◽  
Diagnostic Laboratory ◽  
University Of Missouri ◽  
Angus Cattle ◽  
Biopsy Specimens ◽  
Medical Diagnostic ◽  
Young Cattle ◽  
Mitotic Figures

Ten melanocytomas from 10 cattle were diagnosed by histopathologic examination of biopsy specimens submitted to the Veterinary Medical Diagnostic Laboratory, University of Missouri, between 1 January 1986 and 31 December 1993. One tumor was congenital; the others were first noticed between 2 months and 2 years of age (x = 9.9 months). Six tumors occurred in purebred (3) or crossbred (3) Angus cattle; one tumor each occurred in a Holstein, a Shorthorn, a Simmental, and a beef calf of unrecorded breed or coat color. Five calves were female, and five were male. Five tumors occurred in truncal dermis or subcutis (three in abdominal skin), four occurred on a limb, and one occurred on the jaw. Tumors varied in histologic appearance, but all were pigmented and all had few mitotic figures. Outcome was known for 8/10 cattle. In four cattle followed for at least 1 year, the tumor did not recur after surgical excision. Another heifer had residual gray tissue at the tumor site after surgery but remained in the herd without regrowth of the tumor 30 months after excision. Three other calves were slaughtered within 6 months of excision without apparent recurrence of the tumor.

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