scholarly journals Pandanus odoratissimus(Kewda): A Review on Ethnopharmacology, Phytochemistry, and Nutritional Aspects

2014 ◽  
Vol 2014 ◽  
pp. 1-19 ◽  
Author(s):  
Prafulla P. Adkar ◽  
V. H. Bhaskar

Pandanus odoratissimusLinn. (family: Pandanaceae) is traditionally recommended by the Indian Ayurvedic medicines for treatment of headache, rheumatism, spasm, cold/flu, epilepsy, wounds, boils, scabies, leucoderma, ulcers, colic, hepatitis, smallpox, leprosy, syphilis, and cancer and as a cardiotonic, antioxidant, dysuric, and aphrodisiac. It contains phytochemicals, namely, lignans and isoflavones, coumestrol, alkaloids, steroids, carbohydrates, phenolic compounds, glycosides, proteins, amino acids as well as vitamins and nutrients, and so forth. It is having immense importance in nutrition. A 100 g ediblePandanuspericarp is mainly comprised of water and carbohydrates (80 and 17 g, resp.) and protein (1.3 mg), fat (0.7 mg), and fiber (3.5 g).Pandanusfruits paste provides 321 kilocalories, protein (2.2 g), calcium (134 mg), phosphorus (108 mg), iron (5.7 mg), thiamin (0.04 mg), vitamin C (5 mg), and beta-carotene (19 to 19,000 μg) (a carotenoid that is a precursor to vitamin A).Pandanusfruit is an important source of vitamins C, B1, B2, B3, and so forth, usually prepared as aPandanusfloured drink. Traditional claims were scientifically evaluated by the various authors and the phytochemical profile of plant parts was well established. The methods for analytical estimations were developed. However, there is paucity of systematic compilation of scientifically important information about this plant. In the present review we have systematically reviewed and compiled information of pharmacognostic, ethnopharmacology, phytochemistry, pharmacology, nutritional aspects, and analytical methods. This review will enrich knowledge leading the way into the discovery of new therapeutic agents with improved and intriguing pharmacological properties.

2019 ◽  
Vol 272 ◽  
pp. 227-234 ◽  
Author(s):  
Patrick Riga ◽  
Leyre Benedicto ◽  
Ángel Gil-Izquierdo ◽  
Jacinta Collado-González ◽  
Federico Ferreres ◽  
...  

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Shabbir Hussain ◽  
Shumaila Zulfiqar Butt ◽  
Khurram Shahzad Munawar

Current studies were performed to overview the phytochemistry, nutritional and medicinal value of Ziziphus mauritiana (commonly known as Ber in Pakistan). The leaves of Z. mauritiana are comprised of proteins, amino acids, alkaloids, terpenoids, fibers, flavonoids, tannins, glycosides, and phenolic compounds. The leave majorly demonstrate the presence of α-linolenic acid, plamitic acid and methyl stearate in n-hexane, chloroform and methanol extracts. The seed contains the highest content of carbohydrate (63.24%) and calorific value (411.61 kJ) while its fruit shows the highest quantity of moisture. Its fruit is slightly acidic (pH around 4.77) and rich in nutrients including proteins, carbohydrates vitamin C and minerals (Fe, Zn, Cu, Na, K, Ca, P). The fruit provides energy of 1516-1575 kJ per its 100 g. Z. mauritiana displays antibacterial, antioxidant and anti-inflammatory activities. Its leaves are used for treating tuberculosis, small pox, burning sensations, dysentary asthma, fever, liver issues, infections and blood relating diseases. Root bark of this plant shows good effectiveness as analgesic, anti-inflammatory and anti-allergic agent. The plant displays strong antioxidant potential and excellent H2O2 scavenging activities.


2020 ◽  
Vol 8 (Spl-2-AABAS) ◽  
pp. S286-S291
Author(s):  
Estella Bimenyindavyi ◽  
◽  
Olga Arnoldovna Timofeeva ◽  

This work was carried out for the quantitative estimation of phenolic compounds (soluble phenolic compounds, flavonoids such as quercetin, cynaroside, and avicularin) and ascorbic acid level in the aerial plant parts (leaves and stems) of two sage species viz., Salvia tesquicola (dry-steppe sage) and Salvia verticillata (lilac sage) grown in Tatarstan and Crimea, Kazan, Russia respectively. The highest content of phenolic compounds and the ascorbic acid level was reported in the leaves, while the value of these chemical constitutes was lowest in the stems of both species. Further, it has been shown, that these plants are rich in all investigated chemicals but among these Cynaroside and avicularin are the predominated flavonoids (cynaroside, quercetin, and avicularin). The amount of all studied active compounds differed significantly and it depends on the plant organs, species, and place of growth. Further, the results of the study revealed that the content of soluble phenolic compounds in sage plants did not depend on the species and place of growth while the growing conditions had a greater impact on the amount of flavonoids and vitamin C contents.


2014 ◽  
Vol 15 ◽  
pp. 40-42 ◽  
Author(s):  
N Tsevegsuren ◽  
G Davaakhuu ◽  
Ts Udval

Cynara scolymus L. (Artichoke) is a traditionally consumed vegetable in many countries. In Mongolia, this plant has been successfully cultivated during the last years. The present study is an attempt to investigate the phytochemical composition of C.scolymus L. The result reveals the presence of bioactive constituents comprising flavonoids, total phenolic compounds, saponins and total proteins, carbohydrates, lipids and vitamin C in plant parts. The presence of these phytochemicals can be correlated with the medicinal potential of this plant.DOI: http://doi.dx.org/10.5564/mjc.v15i0.320Mongolian Journal of Chemistry 15 (41), 2014, p40-42


2020 ◽  
pp. 1-9
Author(s):  
G. S. El- Hadidy ◽  
Eman A. Yousef ◽  
A. S. Abd El- Sattar

This work aim to verify the importance of milk thistle seed powder (MTSP) as a medicinal plant and effect of fortification wheat flour (WF) with MTSP on chemical and nutritional properties. Therefore, the chemical composition such as ether extract, dietary fiber, crude protein, vitamin C, amino acids and minerals contents were determined. Also, the antioxidative properties such as phenolic compounds and flavonoid compounds and scavenging activity on DPPH free radicals were also determined. Furthermore, the possibility to use MTSP in bread sticks preparation, where the use of MTSP as replacer of WF at different extents (4, 8 and 12%) to prepare bread sticks rich in protein and minerals, as well as organoleptic evaluation of prepared bread sticks were investigated. Results indicated that MTSP have high amount of protein (25%), ether extract (25.56%), crude fiber (29.68%), minerals content (4.55%), vitamin C (4.59 mg∕g), flavonoids (20,65 mg/g), and phenolic compounds (40.33 mg as Gallic /g) (antioxidants) which, could be used as alternative natural source for synthetic antioxidants in industry. The indispensable and dispensable amino acids are more abundant in MTSP protein. Sensorial evaluation of the obtained products indicated that successful replacement was 4, 8 and 12% of MTSP. So, it could be recommended to use the investigated plant seeds in bread sticks production for its nutritional concept and antioxidative effects. Finally, the use of inexpensive available natural sources of bioactive material and incorporated to our low-cost foods for treatment or protection of our widespread disease is innovated road to produce low price therapeutic foods available to wide levels of our people.   


2020 ◽  
Vol 24 (21) ◽  
pp. 2508-2523
Author(s):  
Johana Gómez ◽  
Diego Sierra ◽  
Constanza Cárdenas ◽  
Fanny Guzmán

One area of organometallic chemistry that has attracted great interest in recent years is the syntheses, characterization and study of organometallic complexes conjugated to biomolecules with different steric and electronic properties as potential therapeutic agents against cancer and malaria, as antibiotics and as radiopharmaceuticals. This minireview focuses on the unique structural diversity that has recently been discovered in α- amino acids and the reactions of metallocene complexes with peptides having different chemical behavior and potential medical applications. Replacing α-amino acids with metallocene fragments is an effective way of selectively influencing the physicochemical, structural, electrochemical and biological properties of the peptides. Consequently, research in the field of bioorganometallic chemistry offers the opportunity to develop bioactive metal compounds as an innovative and promising approach in the search for pharmacological control of different diseases.


2019 ◽  
Vol 20 (9) ◽  
pp. 885-892
Author(s):  
Sara Silva ◽  
Nuno Vale

Cationic antimicrobial peptides (CAMPs) can be considered as new potential therapeutic agents for Tuberculosis treatment with a specific amino acid sequence. New studies can be developed in the future to improve the pharmacological properties of CAMPs and also understand possible resistance mechanisms. This review discusses the principal properties of natural and/or synthetic CAMPs, and how these new peptides have a significant specificity for Mycobacterium tuberculosis. Also, we propose some alternative strategies to enhance the therapeutic activity of these CAMPs that include coadministration with nanoparticles and/or classic drugs.


Author(s):  
Cosmas Chinweike Eze ◽  
Mercy Amarachukwu Ezeokonkwo ◽  
Benjamin Ebere Ezema ◽  
Abraham Efeturi Onoabedje ◽  
David Izuchukwu Ugwu

: Coumarin, sulphonamide and amide scaffolds exhibit diverse pharmacological features and constitute an important class of therapeutic agents. In this review, we have discussed the synthesis, biological properties, and SAR of coumarins containing sulphonamide or amide group in the last seven years. Many reviews on the therapeutic activities of coumarins, sulphonamides, and amides have been published, hence the authors focused on coumarin-linked sulphonamide or amide scaffolds. The review provides information on the synthetic route to new coumarins containing sulphonamide or amide groups with improved pharmacological properties.


Plants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 523
Author(s):  
Stefania Stelluti ◽  
Matteo Caser ◽  
Sonia Demasi ◽  
Valentina Scariot

Tepals constitute the most abundant bio-residues of saffron (Crocus sativus L.). As they are a natural source of polyphenols with antioxidant properties, they could be processed to generate valuable biorefinery products for applications in the pharmaceutical, cosmetic, and food industries, becoming a new source of income while reducing bio-waste. Proper storage of by-products is important in biorefining and dehydration is widely used in the herb sector, especially for highly perishable harvested flowers. This study aimed to deepen the phytochemical composition of dried saffron tepals and to investigate whether this was influenced by the extraction technique. In particular, the conventional maceration was compared with the Ultrasound Assisted Extraction (UAE), using different solvents (water and three methanol concentrations, i.e., 20%, 50%, and 80%). Compared to the spice, the dried saffron tepals showed a lower content of total phenolics (average value 1127.94 ± 32.34 mg GAE 100 g−1 DW) and anthocyanins (up to 413.30 ± 137.16 mg G3G 100 g−1 DW), but a higher antioxidant activity, which was measured through the FRAP, ABTS, and DPPH assays. The HPLC-DAD analysis detected some phenolic compounds (i.e., ferulic acid, isoquercitrin, and quercitrin) not previously found in fresh saffron tepals. Vitamin C, already discovered in the spice, was interestingly detected also in dried tepals. Regarding the extraction technique, in most cases, UAE with safer solvents (i.e., water or low percentage of methanol) showed results of phenolic compounds and vitamin C similar to maceration, allowing an improvement in extractions by halving the time. Thus, this study demonstrated that saffron tepals can be dried maintaining their quality and that green extractions can be adopted to obtain high yields of valuable antioxidant phytochemicals, meeting the requirement for a sustainable biorefining.


Plants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 230
Author(s):  
Oleh Koshovyi ◽  
Ain Raal ◽  
Igor Kireyev ◽  
Nadiya Tryshchuk ◽  
Tetiana Ilina ◽  
...  

The prospect of creating a new medicine with psychotropic activity is shown as a result of studying the chemical composition and pharmacological activity of modified dry extracts of motherwort (Leonurus cardiaca L.) tincture. The most promising substances were the dry extracts, modified by adding small amounts of arginine, valine, phenylalanine, glycine, lysine, and alanine. A total of 15 main phenolic substances were found in the extracts, and eight of them were identified. There were also 10 hydroxycinnamic acids in these extracts, three of which were identified (chlorogenic, caffeic, and rosmarinic acids). The dominant hydroxycinnamic acids were chlorogenic and caffeic acids. Among flavonoids, catechin, hyperoside, and rutin were identified. It should be noted that the extracts had a significant content of ellagic acid. On the basis of the results of the phytochemical analysis of the extracts, it can be concluded that the composition of phenolic compounds does not differ significantly, and the main differences are related to amino acids, which obviously have an impact on the overall pharmacological effect. The results obtained indicate the presence of anxiolytic activity in the motherwort extracts studied in complex with amino acids. The extracts with glycine, valine, and arginine were more effective in reducing anxiety in animals.


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