scholarly journals Phytochemistry of Ziziphus Mauritiana; its Nutritional and Pharmaceutical Potential

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Shabbir Hussain ◽  
Shumaila Zulfiqar Butt ◽  
Khurram Shahzad Munawar

Current studies were performed to overview the phytochemistry, nutritional and medicinal value of Ziziphus mauritiana (commonly known as Ber in Pakistan). The leaves of Z. mauritiana are comprised of proteins, amino acids, alkaloids, terpenoids, fibers, flavonoids, tannins, glycosides, and phenolic compounds. The leave majorly demonstrate the presence of α-linolenic acid, plamitic acid and methyl stearate in n-hexane, chloroform and methanol extracts. The seed contains the highest content of carbohydrate (63.24%) and calorific value (411.61 kJ) while its fruit shows the highest quantity of moisture. Its fruit is slightly acidic (pH around 4.77) and rich in nutrients including proteins, carbohydrates vitamin C and minerals (Fe, Zn, Cu, Na, K, Ca, P). The fruit provides energy of 1516-1575 kJ per its 100 g. Z. mauritiana displays antibacterial, antioxidant and anti-inflammatory activities. Its leaves are used for treating tuberculosis, small pox, burning sensations, dysentary asthma, fever, liver issues, infections and blood relating diseases. Root bark of this plant shows good effectiveness as analgesic, anti-inflammatory and anti-allergic agent. The plant displays strong antioxidant potential and excellent H2O2 scavenging activities.

Antioxidants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 652
Author(s):  
Ye Liu ◽  
Yongli Zhang ◽  
Felix Wambua Muema ◽  
Festus Kimutai ◽  
Guilin Chen ◽  
...  

Carissa spinarum has been traditionally used for the treatment of various diseases due to its different pharmacological activities. However, the active compounds responsible for its potentially specific activities have rarely been explored. To this end, the ethyl acetate (EA) fraction was screened out and selected for further phytochemical isolation because of its promising activities in preliminary 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and COX-2 inhibition assays. As a result, 10 compounds (1−10), including a new one (5), were isolated, with eight of these being identified as phenolic compounds, as expected. Compound 9 possessed an IC50 value of 16.5 ± 1.2 µM, which was lower than that of positive control (vitamin C, 25.5 ± 0.3 µM) in the DPPH assay, and compounds 2, 6, 7 and 9 showed better total antioxidant capacity than vitamin C in the FRAP assay. Meanwhile, compounds 1−6 and 9 also had IC50 values of less than 1.0 µM, which was even better than the positive control indomethacin in the COX-2 inhibition assay. In this context, compounds 2 and 9 were further evaluated to exhibit clear hepatoprotective activities by improving the L02 cell viability and reducing ROS production using a H2O2-induced L02 cell injury model. This study provides initial evidence revealing the most potent phenolic compounds from the root bark of C. spinarum responsible for its antioxidant, anti-inflammatory and hepatoprotective activities.


2019 ◽  
Vol 272 ◽  
pp. 227-234 ◽  
Author(s):  
Patrick Riga ◽  
Leyre Benedicto ◽  
Ángel Gil-Izquierdo ◽  
Jacinta Collado-González ◽  
Federico Ferreres ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-19 ◽  
Author(s):  
Prafulla P. Adkar ◽  
V. H. Bhaskar

Pandanus odoratissimusLinn. (family: Pandanaceae) is traditionally recommended by the Indian Ayurvedic medicines for treatment of headache, rheumatism, spasm, cold/flu, epilepsy, wounds, boils, scabies, leucoderma, ulcers, colic, hepatitis, smallpox, leprosy, syphilis, and cancer and as a cardiotonic, antioxidant, dysuric, and aphrodisiac. It contains phytochemicals, namely, lignans and isoflavones, coumestrol, alkaloids, steroids, carbohydrates, phenolic compounds, glycosides, proteins, amino acids as well as vitamins and nutrients, and so forth. It is having immense importance in nutrition. A 100 g ediblePandanuspericarp is mainly comprised of water and carbohydrates (80 and 17 g, resp.) and protein (1.3 mg), fat (0.7 mg), and fiber (3.5 g).Pandanusfruits paste provides 321 kilocalories, protein (2.2 g), calcium (134 mg), phosphorus (108 mg), iron (5.7 mg), thiamin (0.04 mg), vitamin C (5 mg), and beta-carotene (19 to 19,000 μg) (a carotenoid that is a precursor to vitamin A).Pandanusfruit is an important source of vitamins C, B1, B2, B3, and so forth, usually prepared as aPandanusfloured drink. Traditional claims were scientifically evaluated by the various authors and the phytochemical profile of plant parts was well established. The methods for analytical estimations were developed. However, there is paucity of systematic compilation of scientifically important information about this plant. In the present review we have systematically reviewed and compiled information of pharmacognostic, ethnopharmacology, phytochemistry, pharmacology, nutritional aspects, and analytical methods. This review will enrich knowledge leading the way into the discovery of new therapeutic agents with improved and intriguing pharmacological properties.


2020 ◽  
Vol 68 (2) ◽  
Author(s):  
Turgut Taşkın ◽  
Duygu Taşkın ◽  
Muhammet Emin Çam ◽  
Gizem Bulut

Introduction: Capparis species (Capparaceae), also called caper, grow naturally in various regions of the world. Caper is a plant with medicinal and aromatic properties. Flower buds, root bark, and fruits of the plant are used in folk medicine due to their analgesic, wound healing, cell regeneration, tonic, and diuretic effects. Objective: The aim of this research was to evaluate in vitro (anti-urease, antioxidant, anticholinesterase) and in vivo (anti-inflammatory) biological activities of caper (C. ovata var. canescens). In addition, we aimed to identify its major phenolic compounds using high performance liquid chromatography with a photodiode array detector (HPLC-DAD) and confirmate them using quadrupole time-of-flight liquid chromatography with tandem mass spectrometry (Q-TOF-LC/MS). Also, we quantified the concentrations of several trace and major elements in plant samples using inductively coupled plasma-mass spectrometry (ICP-MS). Methods: The antioxidant, anti-urease and anticholinesterase activities of different plant extracts were evaluated using DPPH, FRAP, ABTS/TEAC, Indophenol and Ellman tests. The identification of phenolic compounds and trace element contents was performed using HPLC and Q-TOF-LC/MS and ICP-MS. Results: Soxhlet methanol extract exhibited the strongest anti-urease, antioxidant (ABTS/TEAC) and anticholinesterase activity. Soxhlet and maceration methanol extracts demonstrated significant anti-inflammatory effect in the altered edema size after the second hour of carrageenan injection. The active phenolic compounds in Soxhlet methanol extract were identified as rutin, quercetin-hexoside-hexoside, quercetin-3-O-hexoside and kaempferol-3-O-rutinoside. In addition, the average concentrations of vanadium, chromium, manganese, cobalt, copper, nickel, arsenic, selenium, zinc and lead were within the permissible limits defined by WHO for medicinal plants. However, it was found that the concentrations of cadmium and iron were higher than the maximum permissible limits. Conclusion: Our results suggest that although caper has a strong biological activity, it should be consumed carefully due to the excess amount of cadmium and iron elements it contains.


Author(s):  
Oleksandr Stremoukhov ◽  
Oleh Koshovyi ◽  
Mykola Komisarenko ◽  
Igor Kireyev ◽  
Andriy Gudzenko ◽  
...  

All over the world, non-steroidal anti-inflammatory drugs (NSAIDs) are taken annually by about three hundred million people and this figure is constantly increasing. At the same time, NSAIDs are also one of the most common causes of side effects of drug therapy. The development and implementation of new anti-inflammatory drugs, including those of plant origin, with minimal side effects is an urgent task of modern pharmaceutical science. Vaccinium corymbosum L. (family Ericaceae), which is gaining more and more popularity among berry crops and is successfully cultivated in Ukraine, is promising in this direction for research. The aim: phytochemical analysis of dry extracts from blueberry leaves to establish the possibility of creating new drugs with anti-inflammatory activity. Materials and methods. The objects of the study were dry extracts of northern highbush blueberry leaves. The content of amino acids and phenolic compounds was determined by HPLC and spectrophotometry. The prototypal activity was studied in vivo and in vitro. Research results. 4 dry extracts were obtained from northern highbush blueberry leaves. In the extracts obtained by HPLC, 7 amino acids were identified, including 3 essential ones: arginine, histidine, and phenylalanine. As a result of the HPLC study, 7 phenolic compounds were identified in extracts from the leaves of northern highbush blueberry: 5 flavonoids - rutin, quercetin-3-O-glucoside, kaempferol-3-O-glucoside, quercetin and kaempferol and 2 hydroxycinnamic acids, chlorogenic and caffeic acid. For the first time, the anti-inflammatory effect of extracts from blueberry leaves was investigated. It was revealed that extract 1 at a dose of 50 mg/kg and extract 4 modified with arginine at a dose of 25 mg/kg have the highest anti-inflammatory activity. Conclusions. The results of the conducted studies indicate that extracts from the leaves of northern highbush blueberry in terms of the content of biologically active substances are promising sources for the creation of new drugs and dietary supplements with anti-inflammatory activity


2018 ◽  
Vol 10 (2) ◽  
pp. 111
Author(s):  
Ekta Singh Chauhan ◽  
Jaya Aishwarya

<p>Chamomile is known as German Chamomile (Marticaria recutita) and Roman Chamomile (Chamaemelum nobile) a very famous daisy plant. The work mainly focuses on the nutraceuticals potential of Chamomile leaf and flower of this plant. The nutrient contains of the leaf and flower power was determined by various methods. The phytochemicals screening of the leaf and flower aqueous extract was performed by the different procedure. Leaf of this plant is rich in carbohydrate, protein, fat and also rich in vitamin C, iron, zinc and calcium. Whereas flower is rich in moisture and fiber as compared to leaf. The aqueous extract of leaf of Chamomile showed the presence of steroids, terpenoids, flavonoids, tannins and saponins and flower were lacked in alkaloids, saponins, gelatin and phenolic compounds. The results record that leaf and flowers powder contains different types of nutrients and phytochmicals in it.<strong> </strong>Chamomile is rich in different bioactive compounds, antioxidant and phytochemicals; carries many pharmacological and traditional properties. Leaves, flowers and stems of Chamomile are used as anti-oxidant, analgesic, anti-viral, anti-inflammatory, anti-septic, anti-diabetic, anti-proliferative, anti-bacterial activities and many more diseases.<strong> </strong>This paper put a light on nutrient content and phytochemical properties of Chamomile leaf and flower.</p>


Author(s):  
Anderson dos Santos Formiga ◽  
Franciscleudo Bezerra da Costa ◽  
Marcio Santos da Silva ◽  
Emmanuel Moreira Pereira ◽  
Yasmin Lima Brasil

<p>O objetivo do trabalho foi disponibilizar informações sobre os aspectos tecnológicos e nutricionais dos frutos do quipá buscando aplicações para o mesmo na alimentação humana. O quipá é uma planta nativa da região Nordeste, seus frutos, ao contrário do figo-da-índia não é valorizado. Os frutos foram colhidos, acondicionados e conduzidos ao laboratório de Análise de Alimentos, CCTA/UFCG, Pombal-PB. Em seguida foram divididos em quatro lotes e submetidos à extração da polpa. Foram avaliadas as características físicas, físico-químicas e químicas dos frutos do quipá. Os frutos são pequenos, a casca representa mais da metade do peso do fruto e com as sementes dificultam a aceitabilidade dos frutos pelo consumidor. A polpa compõe pouco mais de 20% do peso do fruto, possui pH ácido, com baixa concentração de ácido cítrico e sólidos solúveis inferiores aos frutos de figo-da-índia e do mandacaru, comuns ao semiárido; as concentrações de vitamina C e compostos fenólicos na polpa foram consideradas significativas, o que não ocorreu com os flavonoides e antocianinas, que estavam presentes em baixas concentrações.</p><p align="center"><strong><em>Physical and chemical aspects of fruit Quipá (Tacinga inamoena)</em></strong></p><p><strong>Abstract</strong><strong>: </strong>The objective was to provide information on the technological and nutritional aspects of the fruits of Quipá in order to seek applications for the same in human nutrition. The Quipá is a plant native to the Northeast, its fruit, unlike the fig-of-India is not valued. The fruits were harvested, packaged and taken to the Food Analysis Laboratory, CCTA / UFCG, Pombal-PB. They were then divided into four batches and subjected to extraction of the pulp. the physical, physico-chemical and chemical of the fruits of Quipá were evaluated. The fruits are small, the shell is more than half the weight of the fruit and seeds hinder the acceptability of fruit by the consumer. The pulp makes up just over 20% of the fruit weight, has an acidic pH, with low concentration of citric acid soluble solids and lower the fruit of fig-of-India and mandacaru common to semiarid; concentrations of vitamin C and phenolic compounds were considered significant, which did not occur with the flavonoids and anthocyanins, which were present in low concentrations.</p>


2017 ◽  
Vol 12 (2) ◽  
pp. 97-103
Author(s):  
Daniel CORD ◽  
◽  
Mariana POPESCU ◽  
Iulia Burghiu HOBEANU ◽  
Roxana Colette SANDULOVICI ◽  
...  

Introduction. Blackcurrant (Ribes nigrum L.) is a frequently grown cultivated in different parts of the world with a temperate climate. Fruits have a sour taste and they are rich rich source of vitamin C and rutine, organic acids, pectins, essential oils, as well as micro- and macronutrients. Material and method. Several studies have recently been carried out on several vegetable materials in order to find antioxidant and anti-inflammatory substances for the use of vegetable products in various food products or medicinal preparations as substitutes for synthetic substances. Results and discussions. Ribes nigrum contains a large number of phenolic compounds. The blackcurrant shows a number of health benefits attributed to the anti-inflammatory and antioxidant potential.


2020 ◽  
pp. 1-9
Author(s):  
G. S. El- Hadidy ◽  
Eman A. Yousef ◽  
A. S. Abd El- Sattar

This work aim to verify the importance of milk thistle seed powder (MTSP) as a medicinal plant and effect of fortification wheat flour (WF) with MTSP on chemical and nutritional properties. Therefore, the chemical composition such as ether extract, dietary fiber, crude protein, vitamin C, amino acids and minerals contents were determined. Also, the antioxidative properties such as phenolic compounds and flavonoid compounds and scavenging activity on DPPH free radicals were also determined. Furthermore, the possibility to use MTSP in bread sticks preparation, where the use of MTSP as replacer of WF at different extents (4, 8 and 12%) to prepare bread sticks rich in protein and minerals, as well as organoleptic evaluation of prepared bread sticks were investigated. Results indicated that MTSP have high amount of protein (25%), ether extract (25.56%), crude fiber (29.68%), minerals content (4.55%), vitamin C (4.59 mg∕g), flavonoids (20,65 mg/g), and phenolic compounds (40.33 mg as Gallic /g) (antioxidants) which, could be used as alternative natural source for synthetic antioxidants in industry. The indispensable and dispensable amino acids are more abundant in MTSP protein. Sensorial evaluation of the obtained products indicated that successful replacement was 4, 8 and 12% of MTSP. So, it could be recommended to use the investigated plant seeds in bread sticks production for its nutritional concept and antioxidative effects. Finally, the use of inexpensive available natural sources of bioactive material and incorporated to our low-cost foods for treatment or protection of our widespread disease is innovated road to produce low price therapeutic foods available to wide levels of our people.   


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