scholarly journals Synthesis, Characterization, and Antibacterial Activity of Co(II), Ni(II), Cu(II), Zn(II), Cd(II), and Hg(II) Complexes of Schiff's Base Type Ligands Containing Benzofuran Moiety

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
N. Shashidhar Reddy ◽  
B. S. Shankara ◽  
P. Murali Krishana ◽  
C. Basavaraj ◽  
B. Mahesh
Keyword(s):  
Antibacterial Activity ◽  
Metal Ions ◽  
Spectral Data ◽  
General Formula ◽  
Elemental Analysis ◽  
Magnetic Moments ◽  
Good Activity ◽  
Schiff’S Base ◽  
Elemental Data ◽  
Cu Complexes

Six new complexes of Co(II), Ni(II), Cu(II), Zn(II), Cd(II), and Hg(II) with substituted benzofuran derivatives have been synthesized and characterized by elemental analysis, magnetic moments, conductance measurements, spectral characterization, and so forth. Elemental data coincide with the general formula MLC1n, where L = (E)-7-Methoxy-N1-(2,4,5-trimethoxy benzylidene) benzofuran-2-carbohydrazide (L1) or (E)-N1-(2,6-dichloro benzylidene)-7-methoxy benzofuran-2-carbohydrazide (L2), of the complexes. The ligands coordinate to the metal ions through the oxygen of the carbonyl group and the nitrogen of the hydrazine group. Electronic spectral data of the complexes suggests the probable geometry is octahedral in nature. All the complexes and ligands were screened for their antibacterial activity. Among them, Co, Ni, and Cu complexes of L2 showed good activity against all microbes.

scholarly journals Some complexes of N-aryl furfural nitrones with Co (II), Ni (II), Cu (II), Zn (II) and Cd (II) chlorides

2016 ◽  
Vol 4 (1) ◽  
pp. 10
Author(s):  
Amer A. Taqa
Keyword(s):  
Spectral Data ◽  
General Formula ◽  
Elemental Analysis ◽  
13C Nmr ◽  
High Frequency ◽  
Metal Ion ◽  
Uv Spectroscopy ◽  
Active Atom ◽  
Tetrahedral Complexes

Some new metal(II) dichloride complexes with the ligands substituted nitrones of the general formula [ML2Cl2], where M= Co(II), Ni(II), Cu(II), Zn(II) and Cd(II), L=OCH=CHCH=C-CH=N(O)C6H4X (X=H,p-CH3,CH3O,CH3CO,F,Cl,and Br) have been prepared and characterized by elemental analysis, IR,1H,13C NMR and Vis/Uv spectroscopy. The IR spectral data showed that the nitrone ligands coordinated with the metal ion through the most active atom of the N-oxide to give square planner coordinate (Cu,Ni,) complexes and (Zn,Cd,Co) tetrahedral complexes. No correlation was observed between the N-O vibrations stretching high frequency ν (N-O) of the complexes and the Hammet (σ) constants.

scholarly journals Synthesis and Antibacterial Activity of Chalcones and Pyrimidine-2-ones

2005 ◽  
Vol 2 (2) ◽  
pp. 109-112
Author(s):  
A. K. Parekh ◽  
K. K. Desai
Keyword(s):  
Antibacterial Activity ◽  
Spectral Data ◽  
Elemental Analysis ◽  
Aromatic Aldehydes ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
E Coli ◽  
Gram Positive Bacteria ◽  
H Nmr

Some new chalcones have been prepared by Claisen-schmidt condensation of ketone and different aromatic aldehydes. These chalcones on condensation with urea in presence of acid gave Pyrimidine-2-ones. The synthesized compounds have been characterized by elemental analysis, IR and1H NMR spectral data. They have been screened for their antibacterial activity against Gram positive bacteria B. subtillis & S. aureus and Gram negative bacteria E. coli & S. typhi.

scholarly journals Cytotoxic and antimicrobial activities of two new synthetic 2'-oxygenated flavones reported from andrographis viscosula

2007 ◽  
Vol 72 (4) ◽  
pp. 321-329 ◽  
Author(s):  
Sohel Mostahar ◽  
Sayed Alam ◽  
Azizul Islam
Keyword(s):  
Spectral Data ◽  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Brine Shrimp ◽  
Antimicrobial Activities ◽  
Good Activity ◽  
Biocidal Activity ◽  
Fungal Strains ◽  
Bacteria And Fungi

Two new 2'-oxygenated flavones have been synthesized via chalcone precursors and the biocidal activity of these two flavones, along with the corresponding chalcones against microbes (bacteria and fungi) and brine shrimp nauplii were investigated. Both the flavones (compounds 6 and 7) and their corresponding chalcones (compounds 4 and 5) showed good activity against all the tested bacterial and fungal strains. The LC50 values of compounds 4-7 were found to be 2.31, 0.94, 1.39 and 0.58 ?gmL -1, respectively. The synthesized compounds were characterized using UV-Vis, IR, 1H-NMR and 13C-NMR spectral data, together with elemental analysis. .

scholarly journals Synthesis, Characterization and Thermal Studies of Fe(II), Co(II), Ni(II) and Cu(II) Complexes with bis-(4-benzylidenamino-phenyl)-methane Schiff base ligand

2021 ◽  
Vol 2063 (1) ◽  
pp. 012004
Author(s):  
Atared F. Hassan ◽  
Hiba H. Sabah ◽  
Afaq A. Turki
Keyword(s):  
Schiff Base ◽  
Metal Ions ◽  
General Formula ◽  
Elemental Analysis ◽  
Schiff Base Ligand ◽  
Thermal Studies ◽  
Molar Conductivity ◽  
Conductivity Measurements ◽  
Infra Red ◽  
Thermal Stable

Abstract A new series of Co(II), Fe(II), Cu(II) and Ni(II) complexes of Bis–(4-benzylidenamino-phenyl)-methane (L) have been prepared and characterized. The complexes conform to general formula [CoL(H2O)3] Cl2, [FeL(H2O)5]SO4.2H2O, [CuL(H2O)5] NO3 and [NiL(H2O)3Cl2], Infra red spectra and elemental analysis reveal uni-dentate coordination of Schiff base to metal ions. Molar conductivity measurements show that complexes (I, III) behave as 2:1 electrolyte while complex (II) behave as 1:1 electrolyte. The thermal studies for complexes shows that the complexes are thermal stable.

scholarly journals New Cu (II) and Co(II) octaazamacrocyclic complexes with 2-amino-3-phenyl-propanoic acid

2011 ◽  
Vol 76 (5) ◽  
pp. 719-731 ◽  
Author(s):  
Gordana Vuckovic ◽  
Mirjana Antonijevic-Nikolic ◽  
Sladjana Tanaskovic ◽  
Vukosava Zivkovic-Radovanovic
Keyword(s):  
Metal Ions ◽  
General Formula ◽  
Elemental Analysis ◽  
Spectroscopic Data ◽  
Propanoic Acid ◽  
Central Metal ◽  
Cyclic Voltammetric ◽  
Antimicrobial Screening ◽  
Reported Data ◽  
Voltammetric Measurements

New cationic Cu(II) and Co(II) complexes with N,N',N'',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and the anion of 2-amino-3-phenyl-propanoic acid (S-phenylalanine) were prepared. The complexes were analyzed and characterized by elemental analysis, conductometric, polarimetric, magnetic and cyclic voltammetric measurements, as well as by spectroscopic data (UV/Vis, IR). Both complexes are binuclear with the general formula [M2(S-Phe)tpmc](ClO4)3?nH2O; S-PheH = S-phenylalanine, M(II) = Cu, n = 7; Co, n = 0. Based on previously reported data for some familiar complexes and the present results, pentacoordinated geometry was proposed. Both of the central metal ions are coordinated with two pyridyl and two cyclam nitrogens and bridged with -N-(CH2)3-N- portions of the cyclam ring and oxygen atoms of the S-phenylalaninate ion. Antimicrobial screening of the complexes, solvent, starting salts and ligands alone was performed against fungi, mould and some bacteria. In certain cases, enhanced activity of Co(II) complex towards bacteria compared with the relevant free ligands and starting salts was detected.

Synthesis, Characterization and Evaluation of Azetidinylquinolines and Thiazolidinylquinolines as Antibacterial Agents

2014 ◽  
Vol 7 (3) ◽  
pp. 2536-2543
Author(s):  
Shalabh Sharma ◽  
Kuldeep K Saxena
Keyword(s):  
Antibacterial Activity ◽  
Spectral Data ◽  
1H Nmr ◽  
Elemental Analysis ◽  
Antibacterial Agents ◽  
Mass Spectral Data ◽  
Standard Drug ◽  
Mass Spectral ◽  
New Compounds

Several molecules were synthesized like 8-ethoxy-4-methyl-2-amino-(3’-chloro-2’-oxo-4’-substitutedaryl-1’-azeti-dinyl)-quinolines 8-12 and 8-ethoxy-4-methyl-2-amino-(2’-substitutedaryl-4’-oxo-1’,3’-thiazolidin-3’-yl)quinolines 13-17 from 8-ethoxy-4-methyl-2-(substitutedarylidenylimino amino)-quinolines 3-7, and screened to evaluate their antibacterial activity against numerous strains of bacteria        in vitro. The structures of new compounds were established on the basis of their elemental analysis, IR, 1H-NMR and mass spectral data. The results showed that three compounds 10, 11 and 16 were found to exhibit promising antibacterial activity as compared to the standard drug amphicillin.   

scholarly journals Synthesis and Antimicrobial Activity of Some New Substituted Quinoxalines

Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4198 ◽  
Author(s):  
Mohamed A. El-Atawy ◽  
Ezzat A. Hamed ◽  
Mahjoba Alhadi ◽  
Alaa Z. Omar
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Antifungal Activity ◽  
Spectral Data ◽  
Elemental Analysis ◽  
Bacterial Species ◽  
Antimicrobial Spectrum ◽  
Fungal Strains ◽  
Nitrogen Nucleophiles

A number of new symmetrically and asymmetrically 2,3-disubstituted quinoxalines were synthesized through functionalization of 2,3-dichloroquinoxaline (2,3-DCQ) with a variety of sulfur and/or nitrogen nucleophiles. The structures of the obtained compounds were established based on their spectral data and elemental analysis. The antimicrobial activity for the prepared compounds was investigated against four bacterial species and two fungal strains. The symmetrically disubstituted quinoxalines 2, 3, 4, and 5 displayed the most significant antibacterial activity, while compounds 6a, 6b, and the pentacyclic compound 10 showed considerable antifungal activity. Furthermore, compounds 3f, 6b showed broad antimicrobial spectrum against most of the tested strains.

scholarly journals New complexes of Co(II), Ni(II), Cu(II) with Schiff base N,N’-bis-(3-methoxy-saliciliden)-3,3’-dimethylbenzidine

2013 ◽  
Vol 78 (7) ◽  
pp. 947-957 ◽  
Author(s):  
Ionela Alan ◽  
Angela Kriza ◽  
Olguta Dracea ◽  
Nicolae Stanica
Keyword(s):  
Schiff Base ◽  
Thermogravimetric Analysis ◽  
Spectral Data ◽  
Elemental Analysis ◽  
Room Temperature ◽  
Magnetic Moments ◽  
Magnetic Behaviour ◽  
Molar Ratio ◽  
Square Planar ◽  
Perchlorate Complex

The new N,N?-bis-(3-methoxy-saliciliden)-3,3?-dimetilbenzidine (H2L) Schiff base and complexes with Co(II), Ni(II) and Cu(II) of type [M(HL)Cl(H2O)] (M=Co(II), Cu(II)) [M2L(H2O)4]X2 (M=Co(II), X=ClO4 and M=Cu(II), X=NO3) and [M2L(CH3COO)2] (M=Co(II), Ni(II), Cu(II)) were synthesised. The ligand and complexes were characterized by elemental analysis, conductibility measurements, magnetic moments at room temperature, IR, NMR, UV-VIS-NIR, EPR spectra and thermogravimetric analysis. A molar ratio of 1:1 or 1:2 between ligand and metal was determined from the elemental analysis. Except for perchlorate complex that behave as electrolyte, the rest of complexes are non-electrolytes. The spectral data suggest a tetrahedral, pseudo-tetrahedral or square-planar stereochemistry respectively, data confirmed by magnetic behaviour of complexes. The antimicrobial tests indicate a fungicide effect both for ligand and complexes.

scholarly journals Synthesis and Anti-inflammatory Activity of Some Novel 3-(6-Substituted-1, 3-benzothiazole-2-yl)-2-[{(4-substituted phenyl) amino} methyl] quinazolines-4 (3H)-ones

2009 ◽  
Vol 6 (4) ◽  
pp. 1055-1062 ◽  
Author(s):  
Manish Srivastav ◽  
MD. Salahuddin ◽  
S. M. Shantakumar
Keyword(s):  
Antibacterial Activity ◽  
Benzoic Acid ◽  
Spectral Data ◽  
Elemental Analysis ◽  
Inflammatory Activity ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Anti Inflammatory ◽  
Substituted 1 ◽  
Amino Benzoic Acid

A series of novel 3-(6-substituted-1, 3-benzothiazole-2-yl)-2-[{(4-substituted phenyl) amino} methyl] quinazolines-4(3H)-ones were synthesized by treating 2-(chloromethyl)-3-(6-substituted-1, 3-benzothiazole-2-yl) quinazoline-4-(3H)-one (IIa-d) with various substituted amine. The compounds (IIa-d) prepared by treating 2-[(chloroacetyl) amino] benzoic acid with different 2-amino-6-substituted benzothiazole. Elemental analysis, IR,1HNMR and mass spectral data confirmed the structure of the newly synthesized compounds. Synthesized quinazolines-4-one derivative were investigated for their anti-inflammatory and antibacterial activity.

scholarly journals Synthetic studies of Alkoxy isoindole-1,3-diones tetra-azabenzo[f]azulenes and their Antibacterial activity

2006 ◽  
Vol 3 (1) ◽  
pp. 28-34
Author(s):  
M. Ahmed ◽  
R. Sharma ◽  
D. P. Nagda ◽  
V. K. Salvi ◽  
G. L. Talesara
Keyword(s):  
Antibacterial Activity ◽  
Spectral Data ◽  
Elemental Analysis ◽  
Sodium Acetate ◽  
Antibacterial Properties ◽  
Anhydrous Sodium Acetate ◽  
Bacterial Strains ◽  
Substituted Benzaldehydes ◽  
Synthetic Studies

3-Methylpyrazol-5-one3reacts with substituted benzaldehydes4a-din the presence of anhydrous sodium acetate to produce the corresponding 4-arylidene-5-methyl-2,4-dihydro-pyrazol-3-ones5a-dand the condensation of5a-dwith 2-bromoalkoxy-1H-isoindole-1, 3-(2H)-diones2a-cfurnished corresponding 2-[2-(4-arylidene-3-methyl-5-oxo-4,5-dihydro-pyrazol-1-yl)alkoxy]-isoindole-1,3-diones6a-l, which on cyclisation with o-phenylendiamine give titled compounds7a-l. All the synthesized compounds have been characterized by elemental analysis and spectral data and screened for their antibacterial properties against various bacterial strains in order to obtain chemotherapeutic properties.

Sign in / Sign up

Export Citation Format

Share Document