scholarly journals Primary Renal Epithelioid Hemangioendothelioma

2012 ◽  
Vol 2012 ◽  
pp. 1-3
Author(s):  
S. Roy ◽  
A. V. Parwani
Keyword(s):  
Surgical Excision ◽  
Metastatic Potential ◽  
Vascular Tumor ◽  
Metastatic Carcinoma ◽  
Epithelioid Hemangioendothelioma ◽  
High Grade ◽  
Clinical Scenario ◽  
Rare Tumor ◽  
Pathologic Examination ◽  
History Of

Epithelioid hemangioendothelioma is a rare vascular tumor with intermediate biologic behavior and metastatic potential. Primary renal epithelioid hemangioendothelioma is extremely rare and we present the second report of this rare tumor in an interesting clinical scenario. A 59-year-old male with established history of widely metastatic high grade esophageal adenocarcinoma was found to have an isolated renal nodule on a followup computed tomography (CT) scan. Surgical excision, with the suspicion of metastatic carcinoma, and subsequent pathologic examination revealed an epithelioid hemangioendothelioma. The various differential diagnoses and use of morphological clues and immunohistochemistry are discussed.

scholarly journals Intravascular Glomus Tumor of the Forearm Causing Chronic Pain and Focal Tenderness

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Sang Ki Lee ◽  
Dae Geon Song ◽  
Won Sik Choy
Keyword(s):  
Chronic Pain ◽  
Glomus Tumor ◽  
Rare Condition ◽  
Surgical Excision ◽  
Vascular Tumor ◽  
Glomus Tumors ◽  
Contrast Magnetic Resonance ◽  
History Of ◽  
Subcutaneous Layer ◽  
Magnetic Resonance Imaging Mri

Introduction. A glomus tumor is a benign vascular tumor derived from glomus cells and occurs mainly in the subcutaneous layer of the subungual or digital pulp. Extradigital glomus tumors have been reported within the palm, wrist, forearm, foot, bone, stomach, colon, cervix, and mesentery. Glomus tumors can originate from the intraosseous, intramuscular, periosteal, intravascular, and intraneural layers. However, a glomus tumor originating from the intravascular layer of the forearm is a rare condition.Case Report. A 44-year-old woman had a 7-year history of chronic pain and focal tenderness of the forearm. No hypersensitivity or sensory alterations were observed. Contrast magnetic resonance imaging (MRI) showed a mass measuring 5 × 3 × 2 mm leading to a vein. Surgical excision was performed, and the tumor was completely resected. Finding of gross examination revealed a dark-red, well-defined soft tissue tumor, and histologic examination confirmed that the mass was a glomus tumor. The patient’s symptoms were completely resolved postoperatively.Conclusion. Intravascular glomus tumors rarely occur in the forearm; therefore, a thorough physical exam, comprehensive medical history, in-depth imaging, and early surgical excision upon clinical suspicion may be helpful to prevent a delayed or incorrect diagnosis.

scholarly journals Possible toxicity following embolization of congenital giant vertex hemangioma: case report

2017 ◽  
Vol 19 (3) ◽  
pp. 296-299 ◽  
Author(s):  
Ingrid Kieran ◽  
Zaitun Zakaria ◽  
Chandrasekaran Kaliaperumal ◽  
Declan O'Rourke ◽  
Alan O'Hare ◽  
...  
Keyword(s):  
Surgical Excision ◽  
Vascular Tumor ◽  
Percutaneous Injection ◽  
Ethylene Vinyl Alcohol ◽  
First Case ◽  
Immune Mediated ◽  
Embolic Agents ◽  
History Of ◽  
Embolization Procedure ◽  
Toxic Reactions

The authors describe the case of a 3-year-old boy with a giant congenital vertex hemangioma who underwent presurgical embolization with Onyx (ethylene-vinyl alcohol copolymer dissolved in dimethyl sulfoxide) and Glubran (N-butyl-2-cyanoacrylate). This vascular tumor had no intracranial vascular communication as assessed by pre-embolization MRI and catheter angiography. All embolizations were performed by direct percutaneous injection. One week following the last embolization procedure the child presented with a 24-hour history of ataxia and extrapyramidal tremor. He was diagnosed with a possible immune-mediated reaction to Onyx or Glubran, which was treated with an urgent surgical excision of the hemangioma followed by intravenous administration of immunoglobulin and steroids. To the authors' knowledge, this is the first case of possible immune-mediated toxicity secondary to either Onyx or Glubran administration. This case highlights the need for awareness of potential toxic reactions to these embolic agents in the treatment of hemangiomas in the pediatric patient.

scholarly journals Hepatic epithelioid hemangioendothelioma: case series of a rare vascular tumor mimicking metastases

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Nasir Ud Din ◽  
Shabina Rahim ◽  
Tamana Asghari ◽  
Jamshid Abdul-Ghafar ◽  
Zubair Ahmad
Keyword(s):  
Surgical Resection ◽  
Case Series ◽  
Liver Function Tests ◽  
Vascular Tumor ◽  
Metastatic Carcinoma ◽  
Epithelioid Hemangioendothelioma ◽  
Clinicopathological Features ◽  
University Hospital ◽  
Detailed Review

Abstract Background Hepatic epithelioid hemangioendothelioma is an extremely rare malignant vascular tumor which is often multifocal and, in many cases, discovered incidentally. Here, we describe the clinicopathological features of hepatic epithelioid hemangioendothelioma cases seen in our practice and present a detailed review of the published literature. Methods All cases of hepatic epithelioid hemangioendothelioma diagnosed in Department of Pathology and Laboratory Medicine, Aga Khan University Hospital between January 1, 2006 and December 31, 2019 were included in the study. Slides were reviewed and follow up was obtained. Results Seven cases were reported during the study period. There were 4 females and 3 males. Age range was 20 to 77 years, mean age was 45 years. Three patients presented with right upper abdominal pain; 1 patient presented with jaundice while 3 patients were asymptomatic. In all 7 cases, lesions were identified on imaging studies. In 5 cases, liver lesions were multifocal. Clinical differential diagnosis in all cases was metastatic carcinoma and multifocal hepatocellular carcinoma. Liver function tests were normal in 5 cases. In 1 patient, tumor had already metastasized to the right lung. On histological examination of liver core biopsies performed in all 7 cases, classic histological features of epithelioid hemangioendothelioma were seen. Tumor cells expressed positivity for vascular markers (CD 34, CD31 and ERG) and were negative for cytokeratins, Hep par 1 and Glypican 3. Surgical resection was not performed in any of the 7 cases and all patients were treated by chemotherapy. Follow up was available in 5 cases. Of these, 3 patients died of disease and another patient was alive with metastases in both lungs, omentum and colon. Conclusion Clinicopathological features of the 7 cases in our series and detailed review of published literature is presented. Prognosis was bad in our cases most likely due to fact that surgical resection could not be performed in any of the cases owing to lack of surgical expertise for liver tumor surgery in most parts of the country.

scholarly journals Primary Small Cell Carcinoma of the Hypopharynx: A Case Report of a Rare Tumor

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Ali Bayram ◽  
Ebru Akay ◽  
Sema S. Göksu ◽  
İbrahim Özcan
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Systemic Chemotherapy ◽  
Metastatic Potential ◽  
Pyriform Sinus ◽  
Small Cell ◽  
Rare Tumor ◽  
History Of ◽  
The Right

Introduction. Primary hypopharynx involvement of small cell carcinoma is very rare and very few cases have been reported in the literature. Here, we report a case of primary small cell carcinoma of the hypopharynx in a male patient.Case Report. A 50-year-old man presented with a 6-month history of sore throat and swellings in the right side of the neck. Direct laryngoscopy and biopsy revealed small cell carcinoma of the hypopharynx located in the right pyriform sinus.Discussion. Small cell carcinoma of the hypopharynx has no clear treatment modality due to the rarity of the disease. Systemic chemotherapy and radiotherapy should have priority among the therapy regimens because of the high metastatic potential of the tumor.

scholarly journals Extra-Abdominal Fibromatosis (Desmoid Tumor): A Rare Tumor of the Lower Extremity Arising from the Popliteal Fossa

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Mehmet Ali Kaygin ◽  
Ozgur Dag ◽  
Bilgehan Erkut ◽  
Azman Ates ◽  
Refik Cetin Kayaoglu ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Desmoid Tumor ◽  
Aggressive Fibromatosis ◽  
Surgical Excision ◽  
Metastatic Potential ◽  
Vascular Tumor ◽  
Popliteal Fossa ◽  
Surrounding Tissue ◽  
Palpable Mass ◽  
Surgical Specimen

Aggressive fibromatosis is a rare soft tissue tumor. Although it lacks metastatic potential, it can grow aggressively in a locally infiltrating pattern. The tumors frequently recur after surgical excision, which remains the treatment of choice. Optional combinations of radiotherapy and/or chemotherapy have been used postoperatively for recurrent disease and/or inoperable cases. A palpable mass was detected in the popliteal fossa of the right lower extremity in a 48-year-old man. Magnetic resonance imaging showed a contrast-enhancing noncalcified lesion initially felt to represent a vascular tumor. An invasive mass adherent to the surrounding tissue was visualized intraoperatively and extensively debulked. The patient's postoperative course was uneventful. Histologic examination of the surgical specimen was consistent with an extra-abdominal desmoid tumor. After appropriate recognition, wide local excision may be the most appropriate treatment for fibromatosis of the extremity. However, the rarity of this tumor and the difficulty inherent in distinguishing it from similar-appearing tumors are necessitating histologic confirmation of the diagnosis.

scholarly journals Sinonasal Paraganglioma: A Case Report and Review of Literature

2014 ◽  
Vol 7 (2) ◽  
pp. 87-89 ◽  
Author(s):  
Neelam Wadhwa ◽  
PP Singh ◽  
Vipin Arora ◽  
Pankaj Verma ◽  
Khyati Bhatia
Keyword(s):  
Case Report ◽  
Ct Scan ◽  
Nasal Cavity ◽  
Rare Case ◽  
Surgical Excision ◽  
Histopathological Diagnosis ◽  
Rare Tumor ◽  
Review Of Literature ◽  
Diagnostic Challenge ◽  
History Of

ABSTRACT A rare case of sinonasal paraganglioma is described. A 40-year-old female patient presented with 2 years history of unilateral nasal obstruction and bleeding. CT scan demonstrated an expansile enhancing mass involving bilateral ethmoids, right nasal cavity and right maxillary sinus. Histopathological diagnosis was neuroendocrine tumor with possibility of paraganglioma. A subtotal maxillectomy with excision of mass performed. Primary nonchromaffin paraganglioma of nose and paranasal sinus is a very rare tumor, these lesion pose diagnostic challenge to clinicians and pathologist. Only twenty five cases are reported in review of literature. Surgical excision is the mainstay of treatment. How to cite this article Arora V, Verma P, Singh PP, Wadhwa N, Bhatia K. Sinonasal Paraganglioma: A Case Report and Review of Literature. Clin Rhinol An Int J 2014;7(2):87-89.

scholarly journals Unique presentation of palatal metastasis from high-grade spindle cell sarcoma of the bone

2020 ◽  
Vol 13 (11) ◽  
pp. e236652
Author(s):  
Valentina Fenech ◽  
Anton Queen ◽  
Archana Gadve ◽  
Fiona Cowie
Keyword(s):  
Soft Palate ◽  
Spindle Cell ◽  
Bone Cancer ◽  
Surgical Excision ◽  
Malignant Tumour ◽  
Spindle Cell Sarcoma ◽  
High Grade ◽  
Cell Sarcoma ◽  
History Of ◽  
Primary Bone

Spindle cell sarcoma (SCS) is a rare malignant tumour which can arise in bone and accounts for 2%–5% of primary bone cancer cases. Distant metastasis occurs predominantly in the lungs. However, metastasis to the soft palate, to the best of our knowledge, has never been previously reported. In this case report, we describe a unique presentation of soft palate metastasis in a patient with a history of high-grade SCS of the bone who presented with progressive dysphagia and nausea and vomiting who underwent surgical excision for palliation of symptoms.

scholarly journals Dermatofibrosarcoma of the scalp

2019 ◽  
Vol 10 ◽  
pp. 221 ◽  
Author(s):  
Marcos Sangrador ◽  
Jimena González Olvera ◽  
Valeria Mendoza Ortiz
Keyword(s):  
Local Recurrence ◽  
Surgical Management ◽  
Dermatofibrosarcoma Protuberans ◽  
Gross Total Resection ◽  
High Grade ◽  
Rare Tumor ◽  
Parietal Region ◽  
Total Resection ◽  
History Of ◽  
The Right

A 25-year-old woman presented with a 4 months history of progressive pain and tumefaction in the right parietal region. Deformity of the scalp was evident, and a biopsy was taken, reporting a high- grade dermatofibrosarcoma. She underwent surgical management, achieving a gross total resection. Dermatofibrosarcoma protuberans is a rare tumor arising from the dermis. It tends to have an indolent course and local recurrence after excision.

scholarly journals Oral Epithelioid Hemangioendothelioma — Unusual Location of a Rare Entity

2017 ◽  
Vol 2 (4) ◽  
pp. 349-353
Author(s):  
Alina Iacob ◽  
Sebastian Comișel ◽  
Mariana Tilinca ◽  
Tibor Mezei ◽  
Cecilia Petrovan
Keyword(s):  
Oral Cavity ◽  
Immunohistochemical Analysis ◽  
Surgical Excision ◽  
Vascular Tumor ◽  
Epithelioid Hemangioendothelioma ◽  
Rare Entity ◽  
Oncological Treatment ◽  
The Right ◽  
Ulcerative Stomatitis ◽  
Patient’S History

AbstractIntroduction:Epithelioid hemangioendothelioma is a rare, locally aggressive vascular tumor, originating from soft tissue, bone, skin, and organs such as the liver or lung, exceptionally located in the oral cavity. Most of the cases of oral epithelioid hemangioendothelioma are asymptomatic, and diagnosis is hampered by the fact that the histological features are somewhat between hemangioma and angiosarcoma, with epithelioid cells, intracytoplasmic vacuoles, low mitotic activity, and (rarely) necrosis. Immunohistochemical analysis is required to rule out carcinoma or other epithelioid vascular neoplasms.Case presentation:We present a rare case of a 59-year-old Caucasian male patient with oral epithelioid hemangioendothelioma for which clinical and cytological diagnosis was difficult, in spite of the patient’s history. The lesion was nonspecific, mimicking ulcerative stomatitis, but histological and immunohistochemical evaluation finally managed to establish the right diagnosis. Subsequently, the patient underwent surgical excision of the lesion followed by oncological treatment — chemotherapy.Conclusions:Although at first examination seemed that another lesion has developed, rigorous histology and immunohistochemistry tests proved the presence of epithelioid hemangioendothelioma, a very rare entity located in the oral cavity, which required a proper surgical and oncological approach.

scholarly journals Hepatic Epithelioid Hemangioendothelioma

2018 ◽  
Vol 142 (2) ◽  
pp. 263-267 ◽  
Author(s):  
Lynette L. Studer ◽  
Dale M. Selby
Keyword(s):  
Vascular Endothelial Cells ◽  
Incidental Finding ◽  
Treatment Protocol ◽  
Vascular Tumor ◽  
Metastatic Carcinoma ◽  
Epithelioid Hemangioendothelioma ◽  
The Body ◽  
Fusion Product ◽  
Vascular Endothelial ◽  
Abdominal Symptoms

Epithelioid hemangioendothelioma is a rare vascular tumor, composed of epithelioid and histiocytoid vascular endothelial cells in myxoid or fibrotic stroma, which can arise in multiple locations throughout the body. In the liver, this neoplasm usually presents on imaging as an incidental finding of multifocal, heterogeneously enhancing nodules in both lobes or presents clinically with nonspecific abdominal symptoms. Histologically, the tumor has been mistaken for metastatic carcinoma, angiosarcoma, hepatocellular carcinoma, and cholangiocarcinoma. The neoplasm usually stains positive for vascular markers, such as factor VIII–related antigen, CD31, and CD34, and negative for cytokeratins. The translocation t(1;3)(p36.3;q25), resulting in the CAMTA1-WWTR1 fusion product, is the most commonly identified genetic abnormality with this tumor. Although hepatic epithelioid hemangioendothelioma can have a varied clinical course, it is generally considered less aggressive than angiosarcoma. There is no consensus treatment protocol and techniques including liver transplantation, liver resection, chemotherapy and/or radiation therapy, and surveillance have all been used with varying outcomes.

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