scholarly journals B(HSO4)3as an Efficient Catalyst for the Syntheses of Bis(1H-Indol-3-yl)ethanones and Bis(benzotriazol-1-yl)ethanones

2012 ◽  
Vol 9 (1) ◽  
pp. 301-307 ◽  
Author(s):  
Mohammad Hossein Mosslemin ◽  
Abolfazl Eshghi Movahhed
Keyword(s):  
Reaction Time ◽  
Aqueous Media ◽  
Solvent Free ◽  
Simple Experiment ◽  
Efficient Catalyst ◽  
Short Reaction Time ◽  
Work Up

Efficient syntheses of bis (1H-indol-3-yl)ethanones and bis (benzotriazolyl)ethanones via reaction of phenylglyoxals with indole or 1,H-benzotriazole in the presence B(HSO4)3in solvent-free thermal and in aqueous media conditions are discribed. The syntheses have several advantages such as: generality, short reaction time, simple experiment and work-up procedures, excellent isolated yields.

Cyanuric Chloride: an Efficient Catalyst for Ring Opening of Epoxides with Thiols Under Solvent-Free Conditions

2008 ◽  
Vol 61 (3) ◽  
pp. 231 ◽  
Author(s):  
Babasaheb P. Bandgar ◽  
Neeta S. Joshi ◽  
Vinod T. Kamble ◽  
Sanjay S. Sawant
Keyword(s):  
Reaction Time ◽  
Ring Opening ◽  
Solvent Free ◽  
Cyanuric Chloride ◽  
Reaction Conditions ◽  
Efficient Catalyst ◽  
Short Reaction Time ◽  
Solvent Free Conditions ◽  
Ring Opening Of Epoxides

2,4,6-Trichloro-1,3,5-triazine-catalyzed convenient and efficient ring opening of epoxides with thiols under solvent-free conditions is described. Short reaction time, mild reaction conditions, inexpensive and readily available catalyst, and excellent yields of products are attractive features of this methodology.

Solvent-free synthesis of 6-unsubstituted dihydropyrimidinones using 2-pyrrolidonium bisulphate as efficient catalyst

2016 ◽  
Vol 70 (8) ◽  
Author(s):  
Heshmatollah Alinezhad ◽  
Mahmood Tajbakhsh ◽  
Mahboobeh Zare ◽  
Mahbooeh Mousavi
Keyword(s):  
Ionic Liquid ◽  
Reaction Time ◽  
Organic Solvents ◽  
Simple Procedure ◽  
Solvent Free ◽  
One Pot ◽  
Efficient Catalyst ◽  
Short Reaction Time ◽  
Acidic Ionic Liquid ◽  
Solvent Free Synthesis

AbstractA one-pot three-component Biginelli-like reaction of enaminones, aldehydes with urea/thiourea in the presence of 2-pyrrolidonium bisulphate as an acidic ionic liquid catalyst for the preparation of 6-unsubstituted dihydropyrimidinones is described. The excellent yield, short reaction time, simple procedure and avoidance of the use of organic solvents are some advantages of this method.

scholarly journals Friedel-crafts acylation of aromatic compounds using Triflat bismuth

2014 ◽  
Vol 17 (2) ◽  
pp. 10-14
Author(s):  
Phuong Hoang Tran ◽  
Thanh Duy Anh Nguyen ◽  
Thach Ngoc Le
Keyword(s):  
Reaction Time ◽  
Acetic Anhydride ◽  
Lewis Acid ◽  
Aromatic Compounds ◽  
Good Yield ◽  
Efficient Catalyst ◽  
Short Reaction Time ◽  
Mild Conditions ◽  
Bismuth Triflate ◽  
Work Up

Friedel-Crafts acylation of aromatic compounds with acetic anhydride as acylating reagent was investigated in the presence of Lewis acid. Bismuth trifluoromethanesulfonate was found to be efficient catalyst for Friedel-Crafts acetylation under mild conditions. Bismuth triflate is safe-to-handle, simple and clean work-up, good yield and short reaction time

Applications of Selectfluor for the oxidation of Sulfides, urazoles and alcohols under the solvent-free conditions

2020 ◽  
Vol 07 ◽  
Author(s):  
Gholamabbas Chehardoli ◽  
Mohammad Ali Zolfigo ◽  
Shadpour Mallakpour
Keyword(s):  
Reaction Time ◽  
Oxidation Reaction ◽  
Room Temperature ◽  
Lone Pair ◽  
Solvent Free ◽  
Short Reaction Time ◽  
Solvent Free Conditions ◽  
Lone Pair Electron ◽  
Work Up ◽  
Efficient Reagent

: Selectfluor acts as a safe and efficient reagent for the oxidation of urazoles, alcohols and also sulfides via releasing the electrophile F under the solvent-free conditions. In room temperature, this reagent cannot oxidize the substrates alone and requires KBr as the catalyst. In the proposed mechanism, Selectfluor converts the Br- to the Br-F and the lone-pair electron of substrates attack to Br-F to perform the oxidation reaction. This procedure offers some advantages; for example short reaction time, simple work-up, good yield and matching with some green chemistry approaches.

One-Pot, Regioselective Synthesis of Homopropargyl Alcohols using Propargyl Bromide and Carbonyl Compound by the Mg-mediated Reaction under Solvent-free Conditions

2020 ◽  
Vol 17 (6) ◽  
pp. 438-442
Author(s):  
Xiaofang Ma ◽  
Shunxi Li ◽  
Samrat Devaramani ◽  
Guohu Zhao ◽  
Daqian Xu
Keyword(s):  
Reaction Time ◽  
Organic Synthesis ◽  
Carbonyl Compounds ◽  
Solvent Free ◽  
Propargyl Bromide ◽  
Important Goal ◽  
One Pot ◽  
Short Reaction Time ◽  
Solvent Free Conditions ◽  
Volatile Organic

The elimination of volatile organic solvents in organic synthesis is the most important goal in “Green” chemistry. We report a simple, efficient and facile method for the addition of progargyl bromide to carbonyl compounds using Mg metal as a mediator under solvent-free conditions which could regioselectively generate homopropargyl alcohols efficiently in good to excellent yields. The procedure has advantages such as short reaction time, operationally simple, excellent product yields, high regioselectivity and organic solvent-free.

scholarly journals A Simple and Green Protocol for 2H-Indazolo[2,1-b]phthalazine-triones Using Grinding Method

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Xiao-chuan Jia ◽  
Jing Li ◽  
Yu Ding ◽  
Bin Zhang ◽  
Na Wang ◽  
...  
Keyword(s):  
Reaction Time ◽  
Sulfonic Acid ◽  
Catalytic Amount ◽  
Solvent Free ◽  
Short Reaction Time ◽  
Green Protocol ◽  
Simple Operation ◽  
Grinding Method ◽  
Toluene Sulfonic Acid ◽  
High Yields

A robust, facile, and solvent-free route for the three-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones in the presence of a catalytic amount ofp-toluene sulfonic acid utilizing grinding has been developed. Short reaction time, simple operation, and high yields are the advantages of this protocol.

scholarly journals DABCO Catalyzed Synthesis of Xanthene Derivatives in Aqueous Media

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Pradeep Paliwal ◽  
Srinivasa Rao Jetti ◽  
Anjna Bhatewara ◽  
Tanuja Kadre ◽  
Shubha Jain
Keyword(s):  
Reaction Time ◽  
Aqueous Media ◽  
Environmentally Friendly ◽  
The Other ◽  
Short Reaction Time ◽  
Xanthene Derivatives ◽  
Reaction Proceeds ◽  
Conventional Methods

The reaction of 5,5-dimethylcyclohexane-1,3-dione with various heteroarylaldehydes afforded the corresponding heteroaryl substituted xanthene derivatives 1(a–f). The reaction proceeds via the initial Knoevenagel, subsequent Michael, and final heterocyclization reactions using 1,4-diazabicyclo[2.2.2]octane (DABCO) as a catalyst in aqueous media. The synthesized heteroaryl substituted xanthenes 1(a–f) reacted with malononitrile to obtain different alkylidenes 2(a–f). Short reaction time, environmentally friendly procedure, avoiding of cumbersome apparatus, and excellent yields are the main advantages of this procedure which makes it more economic than the other conventional methods.

scholarly journals Green synthesis of 2-aryl-4-phenyl-quınazolıne derıvatives promoted by lactıc acıd

2017 ◽  
Vol 36 (2) ◽  
pp. 223 ◽  
Author(s):  
Belgheis Adrom ◽  
Nourallah Hazeri ◽  
Malek Taher Maghsoodlou ◽  
Mojtaba Lashkari ◽  
Maryam Fatahpour
Keyword(s):  
Lactic Acid ◽  
Reaction Time ◽  
Green Synthesis ◽  
Ammonium Acetate ◽  
Simple Procedure ◽  
Environmentally Benign ◽  
Synthetic Method ◽  
Short Reaction Time ◽  
Quinazoline Derivatives ◽  
Work Up

An environmentally benign three-component synthetic method is described for the construction of 2-aryl-4-phenylquinazoline derivatives from the reaction between aldehydes, ammonium acetate, and 2-aminobenzophenone in the presence of lactic acid in a solvent-less media. The benefits of the reaction were good yields, a simple procedure, simple starting materials short reaction time, easy work-up, and cleaner reaction profiles.

Synthesis of 1H-Chromeno[2,3-d]Pyrimidine-5-Carboxamides under Solvent-Free Conditions at Ambient Temperature

2017 ◽  
Vol 41 (2) ◽  
pp. 85-87 ◽  
Author(s):  
Ghodsyeh Keykha ◽  
Mohammad R. Hosseini-Tabatabaei ◽  
Alireza Hassanabadi
Keyword(s):  
Ambient Temperature ◽  
Present Method ◽  
Barbituric Acid ◽  
Condensation Product ◽  
Solvent Free ◽  
One Pot ◽  
Short Reaction Time ◽  
Alkyl Isocyanide ◽  
Solvent Free Conditions ◽  
Work Up

Good yields of six 1H-chromeno[2,3-d]pyrimidine-5-carboxamides were obtained via the two-stage, one-pot reaction of an alkyl isocyanide with the initially formed condensation product of 1,3-dimethyl barbituric acid and a salicylaldehyde under solvent-free conditions at ambient temperature. This procedure has a number of advantages, such as short reaction time and easy work-up. Also, the present method does not involve any hazardous organic solvent.

TiO2 Nanoparticles as an Efficient Catalyst for the One-pot Preparation of Tetrahydrobenzo[c]acridines in Aqueous Media

2013 ◽  
Vol 68 (4) ◽  
pp. 362-366 ◽  
Author(s):  
Shahrzad Abdolmohammadi ◽  
Mahdieh Mohammadnejad ◽  
Faezeh Shafaei
Keyword(s):  
Ammonium Acetate ◽  
Titanium Dioxide Nanoparticles ◽  
Aqueous Media ◽  
Aromatic Aldehydes ◽  
Catalytic Amount ◽  
One Pot ◽  
Efficient Catalyst ◽  
The One ◽  
Work Up ◽  
Operational Simplicity

A series of tetrahydrobenzo[c]acridinone derivatives have been prepared by a one-pot fourcomponent reaction of 1-naphthol, aromatic aldehydes, dimedone, and ammonium acetate in aqueous media using a catalytic amount of titanium dioxide nanoparticles (TiO2 NPs). The advantages of this novel protocol include the excellent yields, operational simplicity, short reaction time, easy work-up, reusability of the catalyst and an environmentally friendly procedure.

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