scholarly journals Primary Sarcoma of the Specialised Prostatic Stroma: A Case Report and Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-4
Author(s):  
Rosanna Zamparese ◽  
Francesco Corini ◽  
Antonio Braccischi ◽  
Antonella D'Angelo ◽  
Lucilla Diamanti ◽  
...  
Keyword(s):  
Final Diagnosis ◽  
Low Grade ◽  
Review Of The Literature ◽  
Uncertain Malignant Potential ◽  
Primary Sarcoma ◽  
Stromal Sarcoma ◽  
Spindle Cells ◽  
S 100 ◽  
Mitotic Figures ◽  
Transurethral Prostatic Resection

Primary sarcoma tumours of the prostate are rare and are classified, according to their histology, as stromal tumours of uncertain malignant potential (STUMP) and stromal prostatic sarcoma (PS; low and high grade). We describe a case of a 71-year-old man that developed progressive urinary obstruction symptoms and was subjected to a transurethral prostatic resection (TURP). Histologically, there is a diffuse proliferation of epithelioid and spindle cells that showed rare atypical mitotic figures. Immunohistochemically, the neoplastic cells express diffusely CD34 and focally progesterone whereas no immunoreactivity was seen for cytocheratin, desmin, S-100, Bcl-2, chromogranin, CD117, and actin smooth muscle. A final diagnosis of low-grade prostatic stromal sarcoma (LG-PS) was made. This is a really rare neoplasm; in the literature, in fact, to our knowledge, only 6 cases are described and all of these were alive and free of disease at followup. Our patient too is free of disease at 15 months from the diagnosis.

scholarly journals Rare Lipomatous Tumors with Osseous and/or Chondroid Differentiation in the Oral Cavity Report of Two Cases and Review of the Literature

2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
Kayo Kuyama ◽  
Sisilia Fusi Fifita ◽  
Masamichi Komiya ◽  
Yan Sun ◽  
Yoshiaki Akimoto ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Immunohistochemical Study ◽  
Fat Cells ◽  
Fatty Tissue ◽  
Review Of The Literature ◽  
Woven Bone ◽  
Osteoid Tissue ◽  
Spindle Cells ◽  
S 100 ◽  
Lipomatous Tumors

The purpose of this study was to determine the clinicopathological and immunohistochemical features of lipoma/fibrolipoma with rare occasions as osseous and/or chondroid differentiation in the oral cavity. Two cases of the tumors, who presented with a painless, relatively hard mass on the oral mucosa, were studied. These were consisted of a well-circumscribed mass of fatty tissue with chondroid and significant fibrous component intermixed with the lobules of fat cells with chondroid and woven bone component, respectively. Immunohistochemical study revealed that peripheral spindle cells around chondroid tissue stained diffusely for S-100 & and Sox-9, though peripheral spindle cells around osteoid tissue only stained for RUNX-2. According to review of the literature, lipoma/fibrolipoma with osseous and/or chondroid differentiation was 18 cases. Also fibrolipoma with osseous and chondroid differentiation is the first to be reported here. These results indicated that the cartilage/bone is produced by differentiation of undifferentiated mesenchymal cells of stroma.

scholarly journals Periductal Stromal Sarcoma of the Breast: A Case Report

2021 ◽  
Author(s):  
Elham Nazar ◽  
Zohre Shabanzadeh
Keyword(s):  
Breast Cancer ◽  
Radical Mastectomy ◽  
Phyllodes Tumor ◽  
Pathology Report ◽  
Low Grade ◽  
Case Presentation ◽  
Adjuvant Therapies ◽  
Stromal Sarcoma ◽  
Spindle Cells

Introduction: Periductal Stromal Sarcoma (PSS), especially spindle and epithelioid types, is a rare subtype of the malignant fibroepithelial tumor with benign ductal elements and a sarcomatous stroma composed of spindle cells. The therapeutic management of PSS is based on wide surgery with free margins, and adjuvant therapies are not required. Case Presentation: This report describes a 37-year-old woman who presented to Shariati hospital with a right breast mass for review and a second opinion pathology report. The patient had undergone a radical mastectomy in another hospital three months previously. Histological and immunohistochemical examinations revealed PSS and all dissected lymph nodes were free of tumor. Based on the diagnosis, the patient received no adjuvant treatment (such as chemotherapy or radiotherapy). After nine months of close follow-up examinations, no recurrence was observed. Conclusion: PSS is an extremely rare disease with low-grade sarcomatous behavior, which may evolve into a phyllodes tumor or an entity of breast cancer. Therefore, frequent follow-up examinations are required.

scholarly journals Prostatic Stromal Tumor of Uncertain Malignant Potential Which Was Difficult to Diagnose

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Satoko Matsuyama ◽  
Takahiro Nohara ◽  
Shohei Kawaguchi ◽  
Chikashi Seto ◽  
Yuko Nakanishi ◽  
...  
Keyword(s):  
Transurethral Resection ◽  
Digital Rectal Examination ◽  
Radical Resection ◽  
Final Diagnosis ◽  
Malignant Potential ◽  
Stromal Tumor ◽  
Prostatic Urethra ◽  
Uncertain Malignant Potential ◽  
Stromal Sarcoma ◽  
Stromal Tissue

Here, we report a case of stromal tumor of uncertain malignant potential (STUMP) that was difficult to diagnose. A 53-year-old male was found to have a hard nodule on digital rectal examination; magnetic resonance imaging revealed a large nodule on the left side of the prostate, indicating prostate cancer. However, pathological diagnosis of the biopsy specimen was benign prostatic hyperplasia. Although a papillary tumor in the prostatic urethra was also seen on urethrocystoscopy, the tumor specimen obtained from transurethral resection was not malignant. The tumor in the prostatic urethra recurred only 3 months after transurethral resection, and pathological findings revealed benign hyperplasia not only in the stromal tissue but also in the epithelium; therefore, the prostate tumor was suspected to be STUMP. It took many prostate pathologists a long time to reach the final diagnosis of STUMP. STUMP is a rare benign tumor, difficult to diagnose, and sometimes transforms into stromal sarcoma. Thus, we should consider radical resection in such cases.

scholarly journals Endometrial Stromal Sarcoma Arising in Colorectal Endometriosis: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Qiao Wang ◽  
Xia Zhao ◽  
Ping Han
Keyword(s):  
Differential Diagnosis ◽  
English Literature ◽  
Tumor Resection ◽  
Endometrial Stromal Sarcoma ◽  
Low Grade ◽  
Review Of The Literature ◽  
Primary Tumors ◽  
Colorectal Endometriosis ◽  
Stromal Sarcoma ◽  
History Of

Extrauterine endometrial stromal sarcoma (ESS) arising in endometriosis is extremely rare, particularly in the colorectum. It should always be included in the differential diagnosis of primary tumors originating from gastrointestinal tract in females, given that preoperative endoscopical biopsy may reveal no specific changes. We reported a case of ESS arising in colorectal endometriosis and reviewed the previous 7 cases reported in the English literature. Our patient, who was unavailable for tumor resection and refused further adjuvant therapy, played a role in representing the natural history of low-grade extragenital ESS. This case was the only death from ESS arising in colorectal endometriosis.

scholarly journals Periductal Stromal Sarcoma of the Breast: A Case Report

2021 ◽  
Author(s):  
Elham Nazar ◽  
Zohre Shabanzadeh
Keyword(s):  
Breast Cancer ◽  
Radical Mastectomy ◽  
Phyllodes Tumor ◽  
Pathology Report ◽  
Low Grade ◽  
Case Presentation ◽  
Adjuvant Therapies ◽  
Stromal Sarcoma ◽  
Spindle Cells

Introduction: Periductal Stromal Sarcoma (PSS), especially spindle and epithelioid types, is a rare subtype of the malignant fibroepithelial tumor with benign ductal elements and a sarcomatous stroma composed of spindle cells. The therapeutic management of PSS is based on wide surgery with free margins, and adjuvant therapies are not required. Case Presentation: This report describes a 37-year-old woman who presented to Shariati hospital with a right breast mass for review and a second opinion pathology report. The patient had undergone a radical mastectomy in another hospital three months previously. Histological and immunohistochemical examinations revealed PSS and all dissected lymph nodes were free of tumor. Based on the diagnosis, the patient received no adjuvant treatment (such as chemotherapy or radiotherapy). After nine months of close follow-up examinations, no recurrence was observed. Conclusion: PSS is an extremely rare disease with low-grade sarcomatous behavior, which may evolve into a phyllodes tumor or an entity of breast cancer. Therefore, frequent follow-up examinations are required.

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