scholarly journals Long-term treatment of residual or recurrent low-grade endometrial stromal sarcoma with aromatase inhibitors: A report of two cases and a review of the literature

2015 ◽  
Vol 10 (5) ◽  
pp. 3310-3314 ◽  
Author(s):  
HYEWON RYU ◽  
YOON-SEOK CHOI ◽  
IK-CHAN SONG ◽  
HWAN-JUNG YUN ◽  
DEOG-YEON JO ◽  
...  
2003 ◽  
Vol 13 (5) ◽  
pp. 690-692 ◽  
Author(s):  
Y. Saga ◽  
M. Ohwada ◽  
T. Kohno ◽  
N. Takayashiki ◽  
M. Suzuki

Tamoxifen has been widely used in breast cancer treatment. In recent years, the occurrence of uterine malignancies in patients receiving long-term tamoxifen therapy has attracted attention. Most of these malignancies are endometrial adenocarcinomas, but low-grade endometrial stromal sarcomas have occasionally been reported. Here we report a woman who developed a high-grade endometrial stromal sarcoma after receiving postmastectomy tamoxifen therapy. The patient underwent a left mastectomy at age 45 and subsequently received oral tamoxifen for 3 years. At age 51, she was diagnosed with endometrial stromal sarcoma, for which a radical hysterectomy was performed. High-grade endometrial stromal sarcoma was diagnosed by postoperative histologic examination. Immunostaining for the estrogen receptor was negative in sarcoma cells, but positive in the residual endometrial epithelium and the nucleus of adjacent stromal cells within the tumor. The patient has now survived disease-free for 37 months after surgery.


2011 ◽  
Vol 17 (4) ◽  
pp. 348-354 ◽  
Author(s):  
Mika Mizuno ◽  
Yasushi Yatabe ◽  
Akihiro Nawa ◽  
Toru Nakanishi

2006 ◽  
Vol 41 (3) ◽  
pp. 365-369 ◽  
Author(s):  
Masahiro Ochi ◽  
Kazunari Tominaga ◽  
Hirotoshi Okazaki ◽  
Kazuki Yamamori ◽  
Tomoko Wada ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Qiao Wang ◽  
Xia Zhao ◽  
Ping Han

Extrauterine endometrial stromal sarcoma (ESS) arising in endometriosis is extremely rare, particularly in the colorectum. It should always be included in the differential diagnosis of primary tumors originating from gastrointestinal tract in females, given that preoperative endoscopical biopsy may reveal no specific changes. We reported a case of ESS arising in colorectal endometriosis and reviewed the previous 7 cases reported in the English literature. Our patient, who was unavailable for tumor resection and refused further adjuvant therapy, played a role in representing the natural history of low-grade extragenital ESS. This case was the only death from ESS arising in colorectal endometriosis.


2014 ◽  
Vol 3 (1) ◽  
Author(s):  
Katrin Schweneker ◽  
Christoph Clemm ◽  
Melanie Brügel ◽  
Michael Souvatzoglou ◽  
Mirjam Hermisson ◽  
...  

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