CLINICAL DATA ANALYSIS AND MATHEMATICAL MODELING OF MIXED INFECTIONS

1995 ◽  
Vol 03 (02) ◽  
pp. 389-396 ◽  
Author(s):  
MATVEEV A. YU ◽  
A. A. ROMANYUKHA

Quantitative analysis data describing course of viral hepatitis show that concominal viral respiratory infection did not influence hepatitis severity and the rate of recovery after it. In the groups of hepatitis patients with different severity we also found the upper respiratory infections increasing proportional to the hepatitis severity. The rhinoviral infection initiation model in healthy and in hepatitis patients was obtained. Using this model allowed us to describe the phenomenon of upper respiratory infection incidence increasing in viral hepatitis dynamics.

1931 ◽  
Vol 53 (4) ◽  
pp. 447-470 ◽  
Author(s):  
Perrin H. Long ◽  
James A. Doull ◽  
Janet M. Bourn ◽  
Emily McComb

Experimental upper respiratory infections similar to "common colds" were transmitted singly and in series through two and four passages in nine out of fifteen persons, by intransal inoculations with bacteria-free filtrates of nasopharyngeal washings obtained from individuals ill with natural "colds." These observations conform with those reported by previous workers and lend further support to the view that the incitant of the "common cold" is a filtrable virus.


1979 ◽  
Vol 1 (3) ◽  
pp. 76-76

Children with upper respiratory infections who had streptococci excluded by culture were treated with either of the above agents or a placebo. There was no difference among the regimes in overall outcome. Comments: This study would seem superfluous but for the continued promiscuous use of the antibiotics for viral disease in hopes of "preventing complications." It doesn't work. I wish that it did. (R.H.R.)


2008 ◽  
Vol 29 (6) ◽  
pp. 556-558 ◽  
Author(s):  
Ramiro J. Gómez-Villa ◽  
Andreu Comas-García ◽  
Vicente López-Rojas ◽  
Luis F. Pérez-González ◽  
Josefina Sánchez-Alvarado ◽  
...  

We determined the rate of nosocomial viral respiratory infection in infants and the effect of an infection control program during 4 winter seasons. The rate of nosocomial viral respiratory infection decreased from 6.09 episodes per 100 patients admitted during the first study year to 1.46 episodes per 100 patients admitted during the last study year.


2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Sara Ahmadi Badi ◽  
Samira Tarashi ◽  
Abolfazl Fateh ◽  
Pejman Rohani ◽  
Andrea Masotti ◽  
...  

Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is responsible for the outbreak of a new viral respiratory infection. It has been demonstrated that the microbiota has a crucial role in establishing immune responses against respiratory infections, which are controlled by a bidirectional cross-talk, known as the “gut-lung axis.” The effects of microbiota on antiviral immune responses, including dendritic cell (DC) function and lymphocyte homing in the gut-lung axis, have been reported in the recent literature. Additionally, the gut microbiota composition affects (and is affected by) the expression of angiotensin-converting enzyme-2 (ACE2), which is the main receptor for SARS-CoV-2 and contributes to regulate inflammation. Several studies demonstrated an altered microbiota composition in patients infected with SARS-CoV-2, compared to healthy individuals. Furthermore, it has been shown that vaccine efficacy against viral respiratory infection is influenced by probiotics pretreatment. Therefore, the importance of the gut microbiota composition in the lung immune system and ACE2 expression could be valuable to provide optimal therapeutic approaches for SARS-CoV-2 and to preserve the symbiotic relationship of the microbiota with the host.


1996 ◽  
Vol 85 (3) ◽  
pp. 475-480. ◽  
Author(s):  
Mark S. Schreiner ◽  
Irene O'Hara ◽  
Dorothea A. Markakis ◽  
George D. Politis

Background Laryngospasm is the most frequently reported respiratory complication associated with upper respiratory infection and general anesthesia in retrospective studies, but prospective studies have failed to demonstrate any increase in risk. Methods A case-control study was performed to examine whether children with laryngospasm were more likely to have an upper respiratory infection on the day of surgery. The parents of all patients (N = 15,183) who were admitted through the day surgery unit were asked if their child had an active or recent (within 2 weeks of surgery) upper respiratory infection and were questioned about specific signs and symptoms to determine if the child met Tait and Knight's definition of an upper respiratory infection. Control subjects were randomly selected from patients whose surgery had occurred within 1 day of the laryngospasm event. Results Patients who developed laryngospasm (N = 123) were 2.05 times (95% confidence interval 1.21-3.45) more likely to have an active upper respiratory infection as defined by their parents than the 492 patients in the control group (P < or = 0.01). The development of laryngospasm was not related to Tait and Knight's definition for an upper respiratory infection or to recent upper respiratory infection. Children with laryngospasm were more likely to be younger (odds ratio = 0.92, 95% confidence interval 0.87-0.99), to be scheduled for airway surgery (odds ratio = 2.08, 95% confidence interval 1.21-3.59), and to have their anesthesia supervised by a less experienced anesthesiologist (odds ratio = 1.69, 95% confidence interval 1.04-2.7) than children in the control group. Conclusion Laryngospasm was more likely to occur in children with an active upper respiratory infection, children who were younger, children who were undergoing airway surgery, and children whose anesthesia were supervised by less experienced anesthesiologists. Understanding the risk factors and the magnitude of the likely risk should help clinicians make the decision as to whether to anesthetize children with upper respiratory infection.


PEDIATRICS ◽  
2016 ◽  
Vol 137 (4) ◽  
pp. e20153555-e20153555 ◽  
Author(s):  
T. Chonmaitree ◽  
R. Trujillo ◽  
K. Jennings ◽  
P. Alvarez-Fernandez ◽  
J. A. Patel ◽  
...  

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