Time-dependent potentiation of contractile response to norepinephrine in canine isolated cerebral arteries

1991 ◽  
Vol 69 (12) ◽  
pp. 1889-1895 ◽  
Author(s):  
Yasuaki Kawai ◽  
Shin Yokoyama ◽  
Toshio Ohhashi
Keyword(s):  
Time Course ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Contractile Response ◽  
Cerebral Arteries ◽  
Time Dependent ◽  
External Carotid ◽  
Contractile Responses ◽  
Adrenoceptor Agonists ◽  
Internal Carotid Arteries

The time course of contractile responses to α-adrenoceptor agonists was investigated using various arteries isolated from dogs and monkeys. The contractile response to norepinephrine was increased during the time course of the experiment in canine basilar and internal carotid arteries, whereas the response of isolated canine external carotid arteries and monkey internal carotid arteries did not change significantly. Treatment with 10−7 M propranolol, 5 × 10−6 M cocaine plus 10−5 M hydrocortisone, or 5 × 10−5 M acetylsalicylic acid did not significantly affect the time-dependent potentiation of the norepinephrine-induced contraction in canine internal carotid arteries. The time-dependent enhancement in the response to norepinephrine was also observed in the arterial preparations from which the endothelial cells were removed. The contractile response of canine internal carotid arteries to phenylephrine did not alter significantly throughout the experiments. On the other hand, the responses to clonidine and xylazine were markedly enhanced with time. Significant potentiation of the norepinephrine-induced contraction was observed in canine internal carotid arteries treated with 10−8 M prazosin, whereas 10−8 M yohimbine attenuated the time-dependent potentiation. These results suggest that the contractile responses of isolated canine basilar and internal carotid arteries to norepinephrine are potentiated during the course of the experiment, which is likely to be related, in part, to an enhancement in α2-adrenoceptor mediated contraction.Key words: α2-adrenoceptor, dog, cerebral artery, enhancement of contraction, vascular smooth muscle.

DIFFICULTIES IN DIAGNOSING MOYA-MOYA DISEASE (CLINICAL CASE)

2020 ◽  
pp. 48-53
Author(s):  
Novikova I.N. ◽  
Popova T.F. ◽  
Gribacheva I.A. ◽  
Petrova E.V. ◽  
Marushchak A.A. ◽  
...  
Keyword(s):  
Cerebral Angiography ◽  
Neurological Disorders ◽  
Clinical Case ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Cerebral Arteries ◽  
Moya Moya Disease ◽  
Middle Cerebral Arteries ◽  
Internal Carotid Arteries ◽  
Made In

Moya-Moya disease is a rare progressive chronic cer-ebrovascular disease characterized by a narrowing of the lumen of the intracranial segments of the internal carotid arteries, as well as the initial segments of the anterior and middle cerebral arteries with the devel-opment of a network of small vascular anastomoses. Violations of blood supply due to occlusion lead to the development of ischemic strokes in the correspond-ing pools, and ruptures of vascular anastomoses - to the development of hemorrhagic strokes, causing a variety of neurological disorders. The article presents a clinical case of Moya-Moya disease in a 31-year-old patient. The disease was manifested by acute disorders of cerebral circulation in ischemic and hemorrhagic types. The diagnosis was made in accordance with the diagnostic criteria of the disease based on the data of endovascular cerebral angiography.

Embolism from intracranial aneurysms

1980 ◽  
Vol 53 (3) ◽  
pp. 300-304 ◽  
Author(s):  
Toshisuke Sakaki ◽  
Kazuhiko Kinugawa ◽  
Tatsuo Tanigake ◽  
Seiji Miyamoto ◽  
Kikuo Kyoi ◽  
...  
Keyword(s):  
Intracranial Aneurysms ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Cerebral Arteries ◽  
Great Care ◽  
Content Type ◽  
Middle Cerebral Arteries ◽  
Internal Carotid Arteries ◽  
Distal Artery ◽  
Fine Print

✓ Embolism from an aneurysm is one of the mechanisms involved in the pathogenesis of ischemic symptoms associated with intracranial aneurysms. Four cases are reported in which aneurysms of the internal carotid arteries and middle cerebral arteries were the source of emboli resulting in cerebral infarction. In the treatment of these aneurysms, it is best to clip the neck of the aneurysm with great care to avoid embolism due to extrusion of clot into the distal artery.

Unilateral sudden hearing loss as the first presenting symptom of moyamoya disease

2013 ◽  
Vol 127 (2) ◽  
pp. 196-199 ◽  
Author(s):  
L-S Tseng ◽  
S-D Luo
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Moyamoya Disease ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Cerebral Arteries ◽  
Sudden Onset ◽  
Sudden Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Internal Carotid Arteries

AbstractObjective:We describe a rare case of sudden onset of unilateral sensorineural hearing loss occurring as the first symptom of moyamoya disease, which is characterised by progressive stenosis of the intracranial internal carotid arteries and their proximal anterior cerebral arteries and middle cerebral arteries.Method:Case report and review of the world literature regarding moyamoya disease with hearing loss.Results:The reported patient had moyamoya disease that initially presented as sudden, unilateral sensorineural hearing loss. Magnetic resonance imaging showed occlusion of the anterior cerebral, middle cerebral and distal internal carotid arteries bilaterally. The possible mechanism of this patient's sudden sensorineural hearing loss may have been vascular occlusion resulting from thrombotic narrowing or blockage by plaque.Conclusion:The described patient represents the first reported case of sudden onset, unilateral sensorineural hearing loss occurring as the first symptom of moyamoya disease. The possibility of a vascular lesion such as moyamoya disease should be considered in patients with sudden sensorineural hearing loss, especially children, young adults and Asian patients. Due to this disease's poor outcome, early diagnosis and treatment are important to prevent stroke.

scholarly journals Type D Traumatic Carotido-Cavernous Fistula Due to Selective Transection of the Inferolateral Trunk(ILT)

2003 ◽  
Vol 9 (4) ◽  
pp. 373-377 ◽  
Author(s):  
I.C. Duncan ◽  
P.A. Fourie
Keyword(s):  
Carotid Arteries ◽  
Internal Carotid ◽  
Traumatic Injury ◽  
External Carotid Artery ◽  
External Carotid ◽  
Type D ◽  
Type C ◽  
Transvenous Approach ◽  
Internal Carotid Arteries ◽  
Inferolateral Trunk

A minority of traumatic carotido-cavernous fistulas (CCF) are of the indirect variety, and then usually supplied only by meningeal branches of the ipsilateral external carotid artery (Type C). We describe a case of a Type D CCF due to traumatic injury of the inferolateral trunk (ILT), and describe its angiographic features and endovascular management through both the external and internal carotid arteries following a failed transvenous approach.

scholarly journals Unusual position of external carotid artery: a case report

2005 ◽  
Vol 38 (02) ◽  
pp. 170-171
Author(s):  
S B Rao ◽  
V R Vollala ◽  
M Rao ◽  
V P Samuel ◽  
D Deepthinath ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Clinical Importance ◽  
Lateral Position ◽  
External Carotid Artery ◽  
External Carotid ◽  
Unusual Position ◽  
The Common ◽  
Internal Carotid Arteries

AbstractThe arterial pattern of the human body is one of the systems that show a large number of variations. Many reports are available regarding variations of common carotid, external and internal carotid arteries and branches of external carotid artery. We describe a very rare case of lateral position of external carotid artery. The external carotid artery was lateral to the internal carotid artery at the bifurcation of the common carotid artery. The clinical importance of this variation is discussed.

Doppler Angiography for the Non-Invasive Investigation of the Carotid Artery in the Neck

1979 ◽  
Author(s):  
Charles Warlow ◽  
Peter Fish
Keyword(s):  
Carotid Artery ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Doppler Imaging ◽  
Ultra Sound ◽  
External Carotid ◽  
Flow Profile ◽  
Non Invasive ◽  
Velocity Flow ◽  
Internal Carotid Arteries

The accuracy, and possible clinical application of non-invasive ultra sound imaging of the cervical carotid, artery in patients with cerebrovascular disease has been investigated by comparing a pulsed multi-channel directional Doppler imaging devise (“MAVIS” - GEC Medical) with conventional carotid angiography. Of 23 normal or minimally diseased internal carotid arteries only 4 appeared as stenosed on Doppler angiography, the other 19 were normal; of 14 stenosed arteries only 1 appeared normal on imaging,1 appeared occluded end 12 showed clear images of stenosis; all 6 occluded arteries appeared occluded on ultra sound imaging. It was difficult to obtain satisfactory images of the external carotid arteries in all cases. The additional facility to display a velocity flow profile at preselected points along the arterialimage should increase the usefulness of this technique, particularly when there is only minor atheromatous irregularity or ulceration, and such a device will be briefly disrussed.

scholarly journals Stenting in the Remnant of the Third Aortic Arch in a Case of Post-Irradiation Occluded Internal Carotid Artery

2011 ◽  
Vol 17 (1) ◽  
pp. 22-26
Author(s):  
H.-C. Chen ◽  
C.-J. Lin ◽  
F.-C. Chang ◽  
C.-B. Luo ◽  
Y.-J. Lai ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Transluminal Angioplasty ◽  
Artery Occlusion ◽  
Carotid Artery Occlusion ◽  
External Carotid ◽  
First Case ◽  
Internal Carotid Arteries

Collateral networks between the external carotid artery and internal carotid arteries become crucial for cerebral perfusion after occlusion of internal carotid arteries. We report the first case of a patient who received percutaneous transluminal angioplasty and stenting in a collateral vessel between the external and internal carotid artery for treatment of radiation induced severe stenosis of the internal carotid artery in the context of a contralateral internal carotid artery occlusion.

Changes of carotid and vertebral arteries in patents with arterial hypertension and hepatobiliary pathology

2016 ◽  
Vol 94 (1) ◽  
pp. 39-42
Author(s):  
Vladimir Ya. Polyakov ◽  
Yu. A. Nikolaev ◽  
S. V. Pegova ◽  
T. R. Matsievskaya ◽  
I. V. Obukhov
Keyword(s):  
Blood Flow ◽  
Arterial Hypertension ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
External Carotid ◽  
Experimental Medicine ◽  
Laboratory Diagnostics ◽  
Group 2 ◽  
Internal Carotid Arteries ◽  
Group 1

The study included 1172patients (410 men and 762 women) at the mean age of 60.3±10.4years with grade I-II (stage I-II) arterial hypertension (AH) admitted to the clinic of Institute of Experimental Medicine. The patients were divided into 2 groups based on the results of clinical and laboratory diagnostics. Group 1 (n=525) included patients with AH and hepatobiliary system (HBS) diseases, group 2 (n=647) patients with AH without HBS diseases. The patients group 1 had a thicker intima-media complex of carotid arteries, higher peak systolic bloodflow rate in the internal and vertebral carotid arteries, more pronounced coiling of internal carotid arteries than patients of group 2. Patients with AH and HBS diseases exhibited correlation between blood flow rate in external carotid arteries and atherogenicity coefficient. Duplex scanning of neck vessels of in patients with AH without HBS diseases revealed peculiar changes of the intima-media thickness and hemodynamically significant changes of the blood flow in the internal carotid arteries that may be of prognostic value in this nosological syntropy and require the personified approach to diagnostics, treatment, and prevention of these conditions.

CHEMICAL COMPOSITION OF CEREBRAL ARTERIES: THE CONCENTRATION OF LIPIDS AND MINERALS COMPARED WITH THOSE IN THE INTERNAL CAROTID

1954 ◽  
Vol 32 (1) ◽  
pp. 539-547 ◽  
Author(s):  
Robert C. Buck ◽  
James C. Paterson ◽  
Roger J. Rossiter
Keyword(s):  
Total Cholesterol ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Cerebral Arteries ◽  
Disease Process ◽  
Significant Difference ◽  
The Mean ◽  
Severity Of The Disease ◽  
Mean Concentration ◽  
Internal Carotid Arteries

The concentration of total cholesterol, free cholesterol, total phospholipid, nonlipid phosphorus, calcium, and fat-free dry residue was determined in the internal carotid and cerebral arteries obtained at autopsy from a series of 14 male subjects ranging in age from 40 to 85 yr. From these figures the concentration of cholesterol ester and percentage of the total cholesterol in the ester form was calculated.In terms of wet weight, there was, in general, no significant difference between the mean concentration of lipids in the internal carotid arteries and that in the cerebral arteries. On the other hand, the mean concentration of calcium and nonlipid phosphorus was much greater in the internal carotid arteries than in the cerebral arteries.By the method of rank correlation it was found that for both vessels the concentration of total, free, and ester cholesterol was significantly correlated with both age and the severity of the atherosclerosis. Ester cholesterol expressed as a percentage of total cholesterol was also significantly correlated with age and the severity of the disease process.For the internal carotid artery, the concentration of calcium and nonlipid phosphorus was correlated with both age and the severity of the atherosclerosis. This was in contrast to the cerebral arteries in which the concentration of calcium and nonlipid phosphorus was extremely low and was found to be correlated neither with age nor the severity of the disease process.

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