THE POOL SIZE, TURNOVER RATE, AND OXIDATION RATE OF BODY GLUCOSE IN ANESTHETIZED WARM- AND COLD-ACCLIMATED RATS EXPOSED TO A WARM ENVIRONMENT

1959 ◽  
Vol 37 (1) ◽  
pp. 285-295 ◽  
Author(s):  
Florent Depocas
Keyword(s):  
Body Weight ◽  
Plasma Glucose ◽  
Turnover Time ◽  
The Body ◽  
Pool Size ◽  
Glucose Turnover ◽  
Oxidation Rates ◽  
Warm Environment ◽  
Essentially Normal ◽  
The Difference

The size and space of the body glucose pool along with its turnover and oxidation rates have been measured in anesthetized 30° and 6 °C acclimated rats by a method involving continuous intravenous injection of small amounts of D-glucose uniformly labelled with C14 and attainment of relatively constant specific activities of plasma glucose and respiratory CO2. Values of glucose pool space in warm-acclimated rats (essentially normal animals) were in accord with those found in the dog by a similar method. Results obtained on warm-acclimated rats indicated that previous published values of turnover and oxidation rates of glucose for normal rats were high by a factor of approximately 2 to 4. There was, however, close agreement between the values of turnover time of body glucose pool measured by the continuous infusion procedure and those obtained by others with the single intravenous or intraperitoneal injection procedure. In cold-acclimated rats, average absolute values of glucose pool size were significantly smaller than in warm-acclimated rats but the difference was lost when results were related to body weight. Small, non-significant differences in values of glucose pool size per 100 g body weight and in plasma glucose concentration combined to give a significantly larger glucose space in cold-than in warm-acclimated rats. Glucose turnover and oxidation rates, the ratio between these two quantities, and the proportion of respiratory CO2 derived from glucose oxidation were not significantly different in the two groups of rats, thus indicating that cold acclimation is not associated with major alterations in glucose metabolism at least when studied on fully fed anesthetized animals at 30 °C.

THE POOL SIZE, TURNOVER RATE, AND OXIDATION RATE OF BODY GLUCOSE IN ANESTHETIZED WARM- AND COLD-ACCLIMATED RATS EXPOSED TO A WARM ENVIRONMENT

1959 ◽  
Vol 37 (2) ◽  
pp. 285-295 ◽  
Author(s):  
Florent Depocas
Keyword(s):  
Body Weight ◽  
Plasma Glucose ◽  
Turnover Time ◽  
The Body ◽  
Pool Size ◽  
Glucose Turnover ◽  
Oxidation Rates ◽  
Warm Environment ◽  
Essentially Normal ◽  
The Difference

The size and space of the body glucose pool along with its turnover and oxidation rates have been measured in anesthetized 30° and 6 °C acclimated rats by a method involving continuous intravenous injection of small amounts of D-glucose uniformly labelled with C14 and attainment of relatively constant specific activities of plasma glucose and respiratory CO2. Values of glucose pool space in warm-acclimated rats (essentially normal animals) were in accord with those found in the dog by a similar method. Results obtained on warm-acclimated rats indicated that previous published values of turnover and oxidation rates of glucose for normal rats were high by a factor of approximately 2 to 4. There was, however, close agreement between the values of turnover time of body glucose pool measured by the continuous infusion procedure and those obtained by others with the single intravenous or intraperitoneal injection procedure. In cold-acclimated rats, average absolute values of glucose pool size were significantly smaller than in warm-acclimated rats but the difference was lost when results were related to body weight. Small, non-significant differences in values of glucose pool size per 100 g body weight and in plasma glucose concentration combined to give a significantly larger glucose space in cold-than in warm-acclimated rats. Glucose turnover and oxidation rates, the ratio between these two quantities, and the proportion of respiratory CO2 derived from glucose oxidation were not significantly different in the two groups of rats, thus indicating that cold acclimation is not associated with major alterations in glucose metabolism at least when studied on fully fed anesthetized animals at 30 °C.

Glucose metabolism in lactating reindeer

1976 ◽  
Vol 54 (1) ◽  
pp. 55-64 ◽  
Author(s):  
R. G. White ◽  
J. R. Luick
Keyword(s):  
Plasma Glucose ◽  
Transfer Rate ◽  
Turnover Time ◽  
Pool Size ◽  
Glucose Turnover ◽  
Irreversible Loss ◽  
Domestic Species ◽  
Glucose Transfer ◽  
Glucose Synthesis ◽  
Lactation Cycle

Changes in glucose synthesis during the lactation cycle were estimated in pen-fed and grazing reindeer. The pool size, space, transfer rate, and irreversible loss of glucose were determined using simultaneous injections of [2-3H]glucose and primed infusions of [U-14C]glucose in reindeer lactating for 1–2, 4–5, 8–9, and 12–16 weeks. Glucose transfer rate and irreversible loss were higher during early to midlactation than at other times of the year; maximum estimates were at 8–9 weeks postpartum (July), and a decline was noted at 12–16 weeks (August). During the first 1–2 weeks in pen-fed and 4–5 weeks in grazing reindeer, glucose transfer rate and irreversible loss were almost twice the values reported for reindeer at maintenance. No difference in the irreversible loss of glucose was noted between lactating and non-lactating reindeer at 18–20 weeks postpartum (September), and there is evidence that this may occur as early as 12–16 weeks postpartum. No significant trend was noted in the glucose space throughout lactation; however, a significant increase in plasma glucose concentration and pool size was noted when glucose synthesis was highest (8–9 weeks postpartum). Glucose turnover time was consistently faster (78–88 min) in lactating than in non-lactating reindeer (107–140 min). Reindeer used a smaller proportion of plasma glucose-C for lactose synthesis than did other domestic species. This probably results from the low lactose content of reindeer milk and the relatively low rate of milk secretion.

OBSERVATIONS ON THE METABOLIC DISTURBANCES, GROWTH AND BEHAVIOUR OF YOUNG GOATS AFTER TRANSECTION OF THE PITUITARY STALK

1964 ◽  
Vol 45 (1) ◽  
pp. 84-98 ◽  
Author(s):  
P. M. Daniel ◽  
Marjorie M. L. Prichard
Keyword(s):  
Severe Hypoglycaemia ◽  
Hormone Replacement ◽  
Iodine Content ◽  
The Body ◽  
Pituitary Stalk ◽  
Blood Picture ◽  
Metabolic Disturbances ◽  
Essentially Normal ◽  
Target Organs ◽  
The Difference

ABSTRACT In young goats section of the pituitary stalk, with the insertion of a plate to ensure permanent separation of the pituitary gland from the hypothalamus, led to the development of metabolic disturbances including a severe hypoglycaemia. These complications were largely avoided by giving hormone replacement therapy for the first few weeks after operation. The growth of the body and of the target organs (thyroids, adrenals, gonads) was greatly retarded during the first 2 to 4 months; after this the animals increased in size and weight more normally, but the target organs remained very small. The protein-bound iodine content of the serum was low. The blood picture was essentially normal. Although the clinical condition of the goats improved noticeably after a few months their activity continued to be reduced and their behaviour subdued by comparison with normal goats. The difference in the condition of twin goats, in one of which a plate was not inserted, is described.

scholarly journals Effect of certain haematinics on body weight and haemato-biochemical changes in laboratory mice

1970 ◽  
pp. 103-105
Author(s):  
M Jahan ◽  
N Ahmad ◽  
M Myenuddin
Keyword(s):  
Body Weight ◽  
Vitamin B12 ◽  
Biochemical Changes ◽  
The Body ◽  
Treatment Groups ◽  
Group A ◽  
The Difference ◽  
Group B ◽  
Physiology Laboratory ◽  
Hb Concentration

A total of 24, six weeks old mice were used to study the body weight and haemato-biochemical changes following administering of different haematinics (CuSO4, FeSO4 and Vitamin B12). The experiment was performed in Physiology laboratory, Department of Physiology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, from February to March 2006. They were randomly assigned to one of four equal groups (n = 6). In addition to normal rat pellets Group A was supplemented with CuSO4 @ 0.6mg/mice/day orally, Group B with FeSO4 @ 1.2mg/mice/day orally, and Group C with Vitamin B12 (Cytamin®, Glaxo) @ 0.004mg/mice intramuscularly at every 7 days. Group D was considered as control and was also supplemented with rat pellets. Increased body weight was observed in all haematinic treated mice but group B had a significant (p < 0.05) higher weight gain compared to the control. TEC and PCV increased significantly (p < 0.05) in all the treatment groups compared to the control. Statistically insignificant (p > 0.05) increase in TLC was also recorded in all the treated groups. Hb concentration increased for all the treatment groups. The ESR values of the experimental mice were negligible in first hour. The serum transaminases (SGPT and SGOT) increased in all treated groups but the difference in group A was significant (p < 0.05) compared to the control. Blood urea was recorded significantly (P < 0.01) higher for group A and lower for group C compared to the control. This study can be helpful to study the effect of particular haematinic on animal especially on simple stomach animal and human being as mice is used as human and animal model. Key words: Haematinics, haemato-biochemical parameters, mice DOI = 10.3329/bjvm.v5i1.1325 Bangl. J. Vet. Med. (2007). 5 (1 & 2): 103-105

Body glucose as fuel for thermogenesis in the white rat exposed to cold

1960 ◽  
Vol 199 (6) ◽  
pp. 1051-1055 ◽  
Author(s):  
Florent Depocas ◽  
Roberto Masironi
Keyword(s):  
Plasma Glucose ◽  
Turnover Rate ◽  
Glycogen Content ◽  
Liver Glycogen ◽  
Turnover Time ◽  
Cold Environments ◽  
Warm Environment ◽  
White Rats ◽  
Liver Glycogen Content ◽  
Carbohydrate Catabolism

Various parameters of glucose metabolism were measured with C14-glucose in unanesthetized warm- and cold-acclimated rats at 30° and 6°C. Exposure of warm-acclimated rats to cold was associated with a decrease in turnover time of plasma glucose, no change in glucose pool size and space, an increase in rates of turnover and oxidation of body glucose, an increase in the ratio of the oxidation rate to the turnover rate, no change in percentage of respiratory CO2 derived from glucose oxidation, and a decrease in liver glycogen content. Approximately reversed changes were observed in cold-acclimated rats transferred from a cold to a warm environment except in the values of turnover time of plasma glucose and terminal liver glycogen content which underwent smaller changes. It is concluded that cold-induced thermogenesis in white rats, whether acclimated to warm or cold environments, is associated with an increase in carbohydrate catabolism proportionate to the increase in energy metabolism.

scholarly journals The Evaluation of the Body Weight Lowering Effects of Herbal Extract THI on Exercising Healthy Overweight Humans: A Randomized Double-Blind, Placebo-Controlled Trial

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Soo Hyun Cho ◽  
Yoosik Yoon ◽  
Young Yang
Keyword(s):  
Body Weight ◽  
Controlled Trial ◽  
Safety Evaluation ◽  
Hdl Cholesterol ◽  
Treated Group ◽  
The Body ◽  
Herbal Extract ◽  
Double Blind ◽  
The Difference ◽  
Group 2

We investigated the effects of herbal extracts, a mixture of Scutellariae Radix and Platycodi Radix containing the active ingredients Baicalin and Saponin (target herbal ingredient (THI)), on lowering body weight. The present study was a prospective, randomized, double-blind, and placebo-controlled trial carried out at the outpatient department of a hospital over a period of 2 months. Group 1 patients (n=30) received THI, and group 2 patients (n=23) received placebo three times a day before meals. Weight, waist circumference, BMI, total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, and glucose were measured at baseline and again at the 2nd month. For safety evaluation, various hematological and biochemical parameters were assessed. Values of mean change of weight in the THI-treated group were−1.16±1.41 kg and in the placebo-treated group were−0.24±1.70 kg, respectively. The difference in mean change of weight in the THI-treated group compared with that in the placebo-treated group was statistically significant (P<0.05). The incidence of subjective and objective adverse drug reactions was insignificant (P>0.05). THI was statistically significant in its effectiveness on the weight loss.

scholarly journals Reserves to increase beef production and their use

2021 ◽  
Vol 37 ◽  
pp. 00005
Author(s):  
Leonid Kibkalo
Keyword(s):  
Body Weight ◽  
Average Daily Gain ◽  
The Body ◽  
Sales Revenue ◽  
The Third ◽  
Bull Calves ◽  
Morphological Composition ◽  
Special Diets ◽  
The Difference ◽  
Daily Gain

The studies were carried out on three groups of superreplacement heifers of the Simmental breed, which were impregnated at the body weight of 360 kg. In the first group there were 32 unimpregnated heifers, in the second – 28 heifers, in the third – 30 heifers. The heifers of the first group after growing at the age of 18 months were taken for meat. 56 heifers gave the crop. The heifers were transferred for reproduction, and the bull-calves were put on cultivation and further fattening. To obtain well-fed animals, special diets were made so that the average daily gain was at least 650-700 g. After calving, the cows of the second group were taken for meat, and the cows of the third group were put on a 3-month fattening, and then taken for meat. The pre-slaughter weight of animals of the first group was 52 kg lower than that of animals of the second group and 104.7 kg lower than that of the third group. The difference was statistically significant at P>0.999. The interior fat mass was higher in the carcasses of cows of the second group by 1.1 and 3.2 kg compared to the animals of the third and first groups. The carcass yield was almost at the same level slightly ahead of the animals of the first group. Their slaughter yield was 60.1%, in other groups – 58.8-59.6%. The meatiness ratio was slightly higher in animals of the first group. The carcass weight of the first-calf heifers of the third group was 27.4 kg higher than that of the second group. Compared to the first group, this figure is higher by 52.6 kg. Specific carcass meat weight of the animals of the third group was 82.75%, which is higher than in the second and first groups by 0.41-0.85%, respectively. Heavy cowbanes weighing 32.6 and 40.4 kg were obtained from the animals. The skin of animals of the third group was 3.5-21.6 dm2 larger in area than of the animals of the second and first groups. Feeder bull-calves (n=27) had a removable mass of 532 kg. Heavy (282.3 kg) carcasses of good morphological composition were obtained from them. The sales revenue from first-calf heifers (second group) was higher than fattened heifers by 10.4%, and in comparison with fattened animals after calving (third group) it was lower by 9.4%. From the sale of one cow with a crop, 2.9 times more profit was received than from the sale of a heifer.

scholarly journals Investigation of the Effect of Regular Exercise on Some Motoric Features in Children in the 7–12 Age Group

2019 ◽  
Vol 8 (3) ◽  
pp. 81
Author(s):  
Kürşat Hazar
Keyword(s):  
Body Weight ◽  
Exercise Program ◽  
T Test ◽  
The Body ◽  
Control Group ◽  
Regular Exercise ◽  
Age Group ◽  
Paired Samples ◽  
Explosive Force ◽  
The Difference

The aim of this study was to investigate the effects of regular exercise on some motoric features in 7&ndash;12-year-old boys and girls in 8 weeks period of time. To the study 66 boys with an average age of 8, &plusmn; 7963, as 54 of them in research and 12 of them in control groups; 66 girls, 36 of them as research and 30 as control group, a total of 132 individuals who joins summer sports schools within the body of Muğla Sıtkı Ko&ccedil;man Directorate of Health, Culture and Sports with no health problems participated in the study. Two tests were applied to the children before and after the exercise program. Height, body weight, balance, flexibility, bounce force, explosive force, sit-up and 20m velocity measurements were performed to the participants. SPSS 21.00 package program was used for statistical evaluation of the obtained data. For paired comparisons, Paired Samples t test was applied to determine the effect of the independent variable on the dependent variable. In order to determine the difference between the groups, Independent samples t test was applied and the level of significance was set at p &lt;0.05 and 0.01. In the study, statistically significant differences were found in favor of the research group between the first and second measurement results of height, body weight, balance, flexibility, bounce force, explosive force, sit-up and velocity (p &lt;0.05, p &lt;0.01). As a result, in the light of the data obtained from the comparisons between the groups, it was determined that the regularly performed exercises positively affect the body weight, static balance, flexibility, bounce force, explosive force, sit-up and velocity values in 7&ndash;12 age group boys and girls.

scholarly journals Effect of mating method, sex and birth type on growth of lambs

2013 ◽  
Vol 29 (2) ◽  
pp. 277-286 ◽  
Author(s):  
Zoran Ilic ◽  
A. Jevtic-Vukmirovic ◽  
M.P. Petrovic ◽  
V. Caro-Petrovic ◽  
B. Milosevic ◽  
...  
Keyword(s):  
Body Weight ◽  
Statistical Analysis ◽  
Statistical Significance ◽  
Reproductive Traits ◽  
The Body ◽  
Estrus Synchronization ◽  
Body Weights ◽  
The Difference ◽  
Mating Method ◽  
Birth Type

Estrus synchronization methods was use to control the reproductive traits of sheep, as well as bringing more females at the same stage of estrus and ovulation. According to the points mentioned above, the aim of the present study was to investigate and compare mating method and influence of fixed factors on birth and weaning weight of lambs. Statistical analysis showed that exist difference in the body weights between genotypes of lambs. In the first group, the difference in weight of lambs at birth, regardless of mating method was not significant (P> 0.05), while in the second group, the difference was slightly significant (P <0.05). As for the birth type, sex and within the same genotype, there was a statistical significance (P <0.05) between singles obtained naturally, between the triplets obtained naturally and between triplets received hormonal method. All the differences between body weight at 30 days (mating method, sex and birth type under the same genotype) were statistically significant (P <0.05).The determined differences in the body weights at 60 days (sex, mating method and type of birth under the same genotype) were statistically significant (P <0.05). The results showed that the differences (mating method, sex and type of birth under the same genotype) were statistically significant (P <0.05), except in between body weight at 90 days in twins among two genotypes obtained by natural method, which were not statistically significant (P> 0.05).

scholarly journals Analysis of the Factors Influencing Body Weight Variation in Hanwoo Steers Using an Automated Weighing System

Animals ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1270
Author(s):  
Hyunjin Cho ◽  
Seoyoung Jeon ◽  
Mingyung Lee ◽  
Kyewon Kang ◽  
Hamin Kang ◽  
...  
Keyword(s):  
Pattern Recognition ◽  
Body Weight ◽  
The Body ◽  
Individual Animal ◽  
Feeding Patterns ◽  
Factors Affecting ◽  
Factors Influencing ◽  
Weight Variation ◽  
The Difference ◽  
The Individual

This study aimed to determine the factors affecting the body weight (BW) of Hanwoo steers by collecting a large number of BW measurements using an automated weighing system (AWS). The BW of 12 Hanwoo steers was measured automatically using an AWS for seven days each month over three months. On the fourth day of the BW measurement each month, an additional BW measurement was conducted manually. After removing the outliers of BW records, the deviations between the AWS records (a) and manual weighing records (b) were analyzed. BW measurement deviations (a − b) were significantly (p < 0.05) affected by month, day and the time within a day as well as the individual animal factor; however, unexplained random variations had the greatest impact (70.4%). Excluding unexplained random variations, the difference between individual steers was the most influential (80.1%). During the day, the BW of Hanwoo steers increased before feed offerings and significantly decreased immediately after (p < 0.05), despite the constant availability of feeds in the feed bunk. These results suggest that there is a need to develop pattern recognition algorithms that consider variations in individual animals and their feeding patterns for the analysis of BW changes in animals.

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