Microwave-assisted, palladium-catalyzed carbonylative cyclization — Rapid synthesis of 2-quinolones from unprotected 2-iodoanilines and terminal alkynes

2010 ◽  
Vol 88 (4) ◽  
pp. 331-337 ◽  
Author(s):  
Jia-Rong Chen ◽  
Jie Liao ◽  
Wen-Jing Xiao
Keyword(s):  
Carbon Monoxide ◽  
Microwave Irradiation ◽  
Molybdenum Hexacarbonyl ◽  
Terminal Alkynes ◽  
Solid Carbon ◽  
Rapid Synthesis ◽  
Microwave Assisted ◽  
Palladium Catalyzed ◽  
Quinolone Derivatives

Palladium-catalyzed cyclocarbonylations of 2-iodoanilines with various terminal alkynes have been carried out by the use of commercially available molybdenum hexacarbonyl as a convenient and solid carbon monoxide source. The reactions were conducted at 160 °C for 30 min under microwave irradiation and in the presence of Et3N in THF, affording the corresponding 2-quinolone derivatives in good regioselectivities and yields.

Microwave-accelerated, palladium-catalyzed carbonylative cyclization reactions of 2-iodophenol with alkynes — Rapid and efficient synthesis of chromen-2-one derivatives

2005 ◽  
Vol 83 (6-7) ◽  
pp. 826-831 ◽  
Author(s):  
Hong Cao ◽  
Wen-Jing Xiao
Keyword(s):  
Carbon Monoxide ◽  
Microwave Heating ◽  
Molybdenum Hexacarbonyl ◽  
Solid Carbon ◽  
Efficient Synthesis ◽  
Cyclization Reactions ◽  
Palladium Catalyzed

Rapid palladium-catalyzed carbonylative cyclization reactions of 2-iodophenol with various alkynes have been carried out by the use of commercially available molybdenum hexacarbonyl as a convenient and solid carbon monoxide source. The reactions were conducted at 160 °C for 30 min with microwave heating in the presence of DIEA and DMAP in 1,4-dioxane, and afford the corresponding chromen-2-one derivatives in good yields.Key words: microwave, palladium, carbonylation, 2-iodophenol, chromen-2-one.

Microwave-assisted palladium mediated efficient synthesis of pyrazolo[3,4-b]pyridines, pyrazolo[3,4-b]quinolines, pyrazolo[1,5-a]pyrimidines and pyrazolo[1,5-a]quinazolines

RSC Advances ◽  
2014 ◽  
Vol 4 (46) ◽  
pp. 24001-24006 ◽  
Author(s):  
Kommuri Shekarrao ◽  
Partha Pratim Kaishap ◽  
Venkateshwarlu Saddanapu ◽  
Anthony Addlagatta ◽  
Sanjib Gogoi ◽  
...  
Keyword(s):  
Microwave Irradiation ◽  
Efficient Method ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
Aryl Aldehydes ◽  
Microwave Assisted ◽  
Fused Heterocycles ◽  
Palladium Catalyzed ◽  
Solvent Free Reaction

An efficient method was developed for the synthesis of pyrazole fused heterocycles via the palladium-catalyzed solvent free reaction of β-halovinyl/aryl aldehydes and 3-aminopyrazoles/5-aminopyrazoles under microwave irradiation in good yields.

scholarly journals A facile microwave-assisted protocol for rapid synthesis of N-acetylneuraminic acid congeners

2014 ◽  
Vol 38 (2) ◽  
pp. 507-510 ◽  
Author(s):  
Jonel P. Saludes ◽  
Dhananjaya Sahoo ◽  
I. Abrrey Monreal
Keyword(s):  
Microwave Irradiation ◽  
Rapid Synthesis ◽  
Acetylneuraminic Acid ◽  
Microwave Assisted

Microwave irradiation offers expedient access to important Neu5ac derivatives at rates that are 1- to 2-orders of magnitude faster than conventional techniques.

scholarly journals Microwave-assisted synthesis of 7-azaindoles via iron-catalyzed cyclization of an o-haloaromatic amine with terminal alkynes

RSC Advances ◽  
2019 ◽  
Vol 9 (68) ◽  
pp. 39684-39688
Author(s):  
Yi Le ◽  
Zhisong Yang ◽  
Yumei Chen ◽  
Dongmei Chen ◽  
Longjia Yan ◽  
...  
Keyword(s):  
Microwave Irradiation ◽  
Microwave Assisted Synthesis ◽  
Terminal Alkynes ◽  
Practical Procedure ◽  
Microwave Assisted

An efficient and practical procedure was developed to prepare 7-azaindole, starting from an o-haloaromatic amine and corresponding terminal alkynes under microwave irradiation and the scope was demonstrated with a number of examples.

Synthesis of Benzopyran-Fused Flavone Derivatives via Microwave-Assisted Intramolecular C–H Activation

Synthesis ◽  
2018 ◽  
Vol 50 (08) ◽  
pp. 1610-1620 ◽  
Author(s):  
Krisztina Kónya ◽  
Zoltán Sipos
Keyword(s):  
Microwave Irradiation ◽  
Direct Arylation ◽  
Microwave Assisted ◽  
Palladium Catalyzed ◽  
Flavone Derivatives

A microwave-assisted intramolecular direct arylation method for the synthesis of benzopyran-fused flavone derivatives containing natural flavone backbones is described. Different polyalkoxy flavones were synthesized and functionalized with 2-bromobenzyl bromide. The resulting compounds were subjected to palladium-catalyzed intramolecular direct arylation reactions supported by microwave irradiation to produce fused tetracyclic flavones. In the case of the 7-substituted chrysin derivative, the regioselectivity of the coupling was also examined.

Palladium-catalyzed carbonylation of aryl halides: an efficient, heterogeneous and phosphine-free catalytic system for aminocarbonylation and alkoxycarbonylation employing Mo(CO)6 as a solid carbon monoxide source

RSC Advances ◽  
2016 ◽  
Vol 6 (82) ◽  
pp. 78468-78476 ◽  
Author(s):  
Abdol-Reza Hajipour ◽  
Zeinab Tavangar-Rizi ◽  
Nasser Iranpoor
Keyword(s):  
Carbon Monoxide ◽  
Heterogeneous Catalyst ◽  
Catalytic System ◽  
Palladium Nanoparticles ◽  
Aryl Halides ◽  
Solid Carbon ◽  
Highly Efficient ◽  
Palladium Catalyzed

Preparation and characterization of palladium nanoparticles immobilized on magnetic methionine-functionalized chitosan as a highly efficient, air stable, and readily reusable heterogeneous catalyst in carbonylation reactions.

Palladium‐Catalyzed Carbonylative Synthesis of Phthalimides from 1,2‐Dibromoarenes with Molybdenum Hexacarbonyl as Carbon Monoxide Source

2013 ◽  
Vol 355 (18) ◽  
pp. 3581-3585 ◽  
Author(s):  
Xiao‐Feng Wu ◽  
Stefan Oschatz ◽  
Muhammad Sharif ◽  
Anika Flader ◽  
Lisa Krey ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Molybdenum Hexacarbonyl ◽  
Palladium Catalyzed
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