The Effects of Catecholamines, Glucagon, and Diet on Enzyme Activities in Brown Fat and Liver of the Rat

1974 ◽  
Vol 52 (9) ◽  
pp. 739-743 ◽  
Author(s):  
Peter Hahn ◽  
Lorne T. Kirby
Keyword(s):  
Body Weight ◽  
Fatty Acid ◽  
Malic Enzyme ◽  
Phosphoenolpyruvate Carboxykinase ◽  
Fatty Acid Synthetase ◽  
High Carbohydrate Diet ◽  
Brown Fat ◽  
Carbohydrate Diet ◽  
High Carbohydrate ◽  
Cleavage Enzyme

The effects of a high carbohydrate diet fed to young rats for 24–48 h on phosphoenolpyruvate carboxykinase, malic enzyme, citrate-cleavage enzyme, and fatty acid synthetase could be overcome by injecting the animals with glucagon (1 mg/100 g body weight) or norepinephrine (20 μg/100 g body weight) four times a day. The same effect was achieved with 50 mg ephedrine added to the 24 h diet. The catecholamines were more effective in brown fat, whereas glucagon seemed somewhat more effective in the liver.

scholarly journals Effects of an Ad Libitum Low-Fat, High-Carbohydrate Diet on Body Weight, Body Composition, and Fat Distribution in Older Men and Women

2004 ◽  
Vol 164 (2) ◽  
pp. 210 ◽  
Author(s):  
Nicholas P. Hays ◽  
Raymond D. Starling ◽  
Xiaolan Liu ◽  
Dennis H. Sullivan ◽  
Todd A. Trappe ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Fat Distribution ◽  
Older Men ◽  
High Carbohydrate Diet ◽  
Carbohydrate Diet ◽  
Men And Women ◽  
High Carbohydrate ◽  
Ad Libitum ◽  
Older Men And Women

scholarly journals A low-protein, high-carbohydrate diet increases de novo fatty acid synthesis from glycerol and glycerokinase content in the liver of growing rats

2013 ◽  
Vol 33 (6) ◽  
pp. 494-502 ◽  
Author(s):  
Andreza Lúcia Menezes ◽  
Mayara Peron Pereira ◽  
Samyra Lopes Buzelle ◽  
Maísa Pavani dos Santos ◽  
Suélem Aparecida de França ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Synthesis ◽  
De Novo ◽  
Acid Synthesis ◽  
High Carbohydrate Diet ◽  
Carbohydrate Diet ◽  
High Carbohydrate ◽  
Growing Rats ◽  
Low Protein

Low-protein, high-carbohydrate diet increases glucose uptake and fatty acid synthesis in brown adipose tissue of rats

Nutrition ◽  
2014 ◽  
Vol 30 (4) ◽  
pp. 473-480 ◽  
Author(s):  
Suélem Aparecida de França ◽  
Maísa Pavani dos Santos ◽  
Roger Vinícius Nunes Queiroz da Costa ◽  
Mendalli Froelich ◽  
Samyra Lopes Buzelle ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Fatty Acid ◽  
Brown Adipose Tissue ◽  
Fatty Acid Synthesis ◽  
Acid Synthesis ◽  
High Carbohydrate Diet ◽  
Carbohydrate Diet ◽  
High Carbohydrate ◽  
Low Protein ◽  
Brown Adipose

scholarly journals Liver Fatty Acid Composition and Inflammation in Mice Fed with High-Carbohydrate Diet or High-Fat Diet

Nutrients ◽  
2016 ◽  
Vol 8 (11) ◽  
pp. 682 ◽  
Author(s):  
Lorena da Silva-Santi ◽  
Marina Antunes ◽  
Silvana Caparroz-Assef ◽  
Fabiana Carbonera ◽  
Laureane Masi ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
High Fat Diet ◽  
High Carbohydrate Diet ◽  
Liver Fatty Acid ◽  
High Fat ◽  
Carbohydrate Diet ◽  
High Carbohydrate

The effect of starvation on obese mice

1981 ◽  
Vol 59 (4) ◽  
pp. 355-357 ◽  
Author(s):  
P. Hahn ◽  
J. P. Skala
Keyword(s):  
Fatty Acid ◽  
Plasma Levels ◽  
Phosphoenolpyruvate Carboxykinase ◽  
Fatty Acid Synthetase ◽  
Brown Fat ◽  
Obese Group ◽  
Synthetase Activity ◽  
Obese Mice ◽  
Carnitine Acetyltransferase ◽  
Total Carnitine

Plasma levels of total and acylcarnitine and the activities of carnitine acetyltransferase (CAT) and carnitine, palmitoyltransferase (PCT) in liver and CAT in brown fat were determined in young obese (ob/ob) mice and their littermates during starvation. Plasma levels of acylcarnitine and β-hydroxybutyrate rose equally in both groups. Total carnitine levels, however, decreased in lean and rose in obese animals. Hepatic PCT and phosphoenolpyruvate carboxykinase activities rose more in lean than obese mice and brown fat CAT activity decreased in the obese group. Fatty acid synthetase activity decreased equally in the liver in obese mice and their lean littermates.

scholarly journals ANTIOBESITY OF FRACTIONS WATER EXTRACT OF TAMARIND (TAMARINDUS INDICA L.) IN MALE WISTAR RATS INDUCED HIGH CARBOHYDRATE DIET

2018 ◽  
Vol 11 (13) ◽  
pp. 200
Author(s):  
Nurul Hidayah ◽  
Ketut Adnyana I ◽  
Ketut Adnyana I ◽  
Neng Fisheri ◽  
Neng Fisheri ◽  
...  
Keyword(s):  
Body Weight ◽  
Ethyl Acetate ◽  
Wistar Rats ◽  
Water Extract ◽  
Ethyl Acetate Fraction ◽  
High Carbohydrate Diet ◽  
Carbohydrate Diet ◽  
High Carbohydrate ◽  
Male Wistar Rats ◽  
Weight Decrease

Objective: The prevalence of obesity increases each year globally. Multifactorial etiology of obesity requires therapy management including changing of diet and medicines. Some of obesity drugs have shown ineffectiveness and safety. The previous study showed that water extract of tamarind could reduce body weight (bw). This study aimed to test the activity fraction of water extract tamarind as antiobesity using high carbohydrate diet.Method: The preventive research of antiobesity had done by given water fraction and ethyl acetate fraction of water extract tamarind following with induced high carbohydrate diet during 6th weeks in male Wistar rats. The parameters had observed including consumption of food, body weight, weight of feces, volume of urine, total cholesterols, triglycerides, blood glucose, index of organs, and accumulation of body fat.Result: The ethyl acetate fraction at doses 4.5 mg/kg bw has shown significantly effect to decrease of total cholesterols level and decrease of triglycerides level at weeks 6 (p<0.05). All the tests of fraction have shown activity inhibition of increased body weight, decrease of appetite, total cholesterols, triglycerides, and blood glucose. Meanwhile, mechanism action of antiobesity as increase defecation, urination, and decrease index of organs and accumulation of body fat have not shown by all these test fractions.Conclusion: The ethyl acetate fraction at doses of 4.5 mg/kg bw can inhibit raising of body weight, decrease of total cholesterols, and triglycerides level greater than the other test groups, where increasing of these levels of blood biochemistry was closely related to the pathology of obesity.

Abstract P366: A High-carbohydrate Diet Increases Serum HDL-C and Apolipoprotein A-I and Decreases Weight and BMI in the Male A Carriers of the APOA1 -75G/A Polymorphism

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Yong Yan Song ◽  
Ren Rong Gong ◽  
Min Shan Hu ◽  
Zhen Zhang ◽  
Hui Liu ◽  
...  
Keyword(s):  
Body Weight ◽  
Serum Lipid ◽  
Serum Lipids ◽  
Density Lipoprotein ◽  
High Carbohydrate Diet ◽  
Energy Restriction ◽  
Carbohydrate Diet ◽  
High Carbohydrate ◽  
Apolipoprotein A ◽  
Anthropometric Indexes

Both apolipoprotein gene polymorphism and high-carbohydrate diet have been found to be associated with serum lipid levels. However, the effects of their interaction on serum lipid profiles have not been well elucidated yet. We assessed the hypothesis that the subjects with different genotypes of the -75G/A polymorphism in the promoter region of the apolipoprotein A-I gene ( APOA1 ) have different serum lipid responses upon a high-carbohydrate diet. Fifty-six healthy university students (27 males and 29 females, 22.89&#177;1.80 years) were given a washout diet of 54% carbohydrates for seven days, followed by a high-carbohydrate diet of 70% carbohydrates for six days without total energy restriction. Anthropometric indexes and serum lipids at baseline, after the washout diet, and after the high-carbohydrate diet, as well as the APOA1 -75G/A polymorphism were analyzed. The male A carriers of the APOA1 -75G/A polymorphism consistently had higher levels of apolipoprotein A-I ( p =0.008 at baseline, p =0.031 after the washout diet, and p =0.009 after the high-carbohydrate diet diet), but higher levels of high-density lipoprotein cholesterol (HDL-C) only at baseline ( p =0.048) and after the high-carbohydrate diet ( p =0.042) than the males with the GG genotype, and experienced increases in HDL-C ( p =0.023) and apolipoprotein A-I ( p =0.012) and decreases in body weight ( p =0.017) and body mass index (BMI) ( p =0.018) after the high-carbohydrate diet when compared to those after the washout diet. In conclusion, the high-carbohydrate diet can increase the serum HDL-C and apolipoprotein A-I concentrations in the males carrying the A allele of the APOA1 -75G/A polymorphism. The effects are associated with the decreases of body weight and BMI. These results may provide experimental evidences for the personalized dietary interference in the country with the largest population in the world.

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