EXPERIMENTS ON ATROPINE-RESISTANT VASODILATATION IN SALIVARY GLANDS

1963 ◽  
Vol 41 (2) ◽  
pp. 519-524 ◽  
Author(s):  
B. C. R. Strömblad ◽  
Peter E. Dresel

Vasodilatation induced by stimulation of the parasympathetic nerve supply to the submaxillary and the parotid glands has long been known to be resistant to the blocking effect of atropine. We have found that dichloroisoproterenol does not block this vasodilatation, that d-tubocurarine blocks it by interfering with ganglionic transmission, and that a hemicholinium, HC-3, blocks it gradually under conditions in which interference with ganglionic transmission is excluded. It is concluded that the mechanism of vasodilatation includes the action of cholinergic nerves.

1963 ◽  
Vol 41 (1) ◽  
pp. 519-524
Author(s):  
B. C. R. Strömblad ◽  
Peter E. Dresel

Vasodilatation induced by stimulation of the parasympathetic nerve supply to the submaxillary and the parotid glands has long been known to be resistant to the blocking effect of atropine. We have found that dichloroisoproterenol does not block this vasodilatation, that d-tubocurarine blocks it by interfering with ganglionic transmission, and that a hemicholinium, HC-3, blocks it gradually under conditions in which interference with ganglionic transmission is excluded. It is concluded that the mechanism of vasodilatation includes the action of cholinergic nerves.


1985 ◽  
Vol 30 (11-12) ◽  
pp. 773-775 ◽  
Author(s):  
J. Ekström ◽  
B. Månsson ◽  
B.-O. Nilsson ◽  
Elsa Rosengren ◽  
G. Tobin

1974 ◽  
Vol 31 (03) ◽  
pp. 403-414 ◽  
Author(s):  
Terence Cartwright

SummaryA method is described for the extraction with buffers of near physiological pH of a plasminogen activator from porcine salivary glands. Substantial purification of the activator was achieved although this was to some extent complicated by concomitant extraction of nucleic acid from the glands. Preliminary characterization experiments using specific inhibitors suggested that the activator functioned by a similar mechanism to that proposed for urokinase, but with some important kinetic differences in two-stage assay systems. The lack of reactivity of the pig gland enzyme in these systems might be related to the tendency to protein-protein interactions observed with this material.


1973 ◽  
Vol 138 (3) ◽  
pp. 407-420 ◽  
Author(s):  
Per Alm ◽  
Gunnar D. Bloom ◽  
Bengt Carls��

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