THE PARTICIPATION OF THE LIVER IN THE FORMATION OF POSTHEPARIN ESTERASES

1961 ◽  
Vol 39 (9) ◽  
pp. 1467-1470 ◽  
Author(s):  
J. Kohout ◽  
L. Korbová ◽  
J. Skořepa

The task of the study was to ascertain the participation of the liver in the formation of postheparin esterases. The chronic experiments were carried out on dogs with acrylic vascular cannulas placed into the hepatic vein and vena portae according to London. The modified operation is described in the paper in detail. Heparin was administered in the dose of 200 I.U. per 1 kg body weight into vena portae or one of the hepatic veins. Blood was drawn from these veins at short simultaneous intervals and the activity of postheparin esterases was determined in it. The activity of serum esterases was estimated by the Cherry–Crandall method. Control trials were carried out to study the activity of serum esterases after the administration of saline. The results suggest that postheparin esterases originate in the liver.

2021 ◽  
pp. 1-2
Author(s):  
V.P.S. Punia ◽  
Praveen Raman Mishra ◽  
Shaavi Mittal ◽  
Akash Bharti ◽  
Prem Kumar ◽  
...  

In developing countries Amoebic liver abscess is commonly encountered disease and it’s also the commonest extraintestinal manifestation of Entamoeba histolytica infection. Usual complication of Amoebic liver abscess arises due to collection of pus in various cavities, like in peritoneal cavity following perforation, in the pleural cavity which is known as empyema thoracis, and rarely it is complicated by life threatening conditions such as venous extension of the disease involving the hepatic veins and IVC, with only few cases reported. Here we describe a case of amoebic liver abscess extending across middle hepatic vein.


2018 ◽  
Vol 7 ◽  
pp. e1140
Author(s):  
Hadi Zare Marzouni ◽  
Behrooz Davachi ◽  
Mahdi Rezazadeh ◽  
Mahmoud Salehi Milani ◽  
Sedighe Matinfard

Background: Cirrhosis is a common disease that destroys liver cells, and it has various etiologies. The early diagnosis of cirrhosis can be effective in improving prognosis.Considering the availability and affordability of ultrasound devices throughout the world, in this study we evaluated the diagnostic value of hepatic vein ultrasound examination in the early detection of liver cirrhosis.Materials and Methods: In this study, 45 patients referred to the radiology department of Ghaem Hospital for liver biopsy were evaluated for changes in the hepatic veins under ultrasound with a transducer of 5-7MHz. One piece of the hepatic vein was selected for ultrasound, and the wall of hepatic veins was examined for straightness and uniformity of echogenicity. Subsequently, patients underwent biopsy by ultrasound guide.  Of all the study subjects, eight patients presented mild chronic hepatitis without fibrosis, four patients were diagnosed with fatty liver, and 33 patients had severe cirrhosis or chronic hepatitis with fibrosis.Results: Our results showed that hepatitis patients with or without fibrosis had irregular and wavy hepatic vein wall (impairment in straightness) with non-uniform echo (impairment in uniformity of echogenicity). While patients without hepatitis and cirrhosis, but diagnosed with fatty liver, had a smooth and regular hepatic vein wall with a uniform echo.Conclusion: The present study showed that hepatic vein examination in terms of echogenicity and straightness could be used to diagnose hepatitis, its severity as well as its course towards fibrosis and cirrhosis. [GMJ.2018;7:e1140]


2008 ◽  
Vol 34 (2) ◽  
pp. 247-251 ◽  
Author(s):  
M.A. Machado ◽  
T. Bacchella ◽  
F.F. Makdissi ◽  
R.T. Surjan ◽  
M.C. Machado

1965 ◽  
Vol 43 (5) ◽  
pp. 585-593 ◽  
Author(s):  
J. Tinoco ◽  
R. L. Lyman ◽  
Ruth Okey

Blood samples were taken from the femoral and hepatic veins of the same rat. The blood from the hepatic vein had a higher concentration of glucose than blood from the femoral vein. Plasma from the femoral vein always had a higher level of cholesteryl esters than plasma from the hepatic vein, indicating that the liver was absorbing cholesteryl esters. Fatty acid patterns were determined for plasma cholesteryl esters, triglycerides, and phospholipids; there was little difference in pattern between samples taken from the hepatic vein and samples from the femoral vein.


Fractals ◽  
2003 ◽  
Vol 11 (01) ◽  
pp. 53-62 ◽  
Author(s):  
HORST K. HAHN ◽  
CARL J. G. EVERTSZ ◽  
HEINZ-OTTO PEITGEN ◽  
JEAN H. D. FASEL

The scaling properties of the portal vein and the hepatic vein are examined, based on three-dimensional computed tomography images of casts of human livers. In particular, a quantitative analysis of the branching ratio based on the Strahler ordering scheme as well as the diameter and length ratios are performed. To quantify the segment anatomy of the liver, the volume of supplied liver parenchyma is measured and related to the corresponding vessel radius. The implications of these findings for segment-oriented liver surgery are discussed. We also investigate the 3D interdependence of the intertwined portal and hepatic veins based on a concept of tree distance that will be introduced.


HPB Surgery ◽  
1989 ◽  
Vol 1 (2) ◽  
pp. 155-160 ◽  
Author(s):  
John M. Howard ◽  
M. Malafa ◽  
Robert J. Coombs ◽  
Anthony M. Iannone

A patient is presented with multiple vascular anomalies in the branches of the celiac axis as well as in the portal vein and its branches. Apparently, unique in the literature is the presence of a large arteriovenous fistula between the hepatic artery and one of the hepatic veins. The anomalies are presumed to be congenital in origin.


2017 ◽  
Author(s):  
E. Finnerty ◽  
R. Ramasawmy ◽  
J. O’Callaghan ◽  
J. Connell ◽  
M. F. Lythgoe ◽  
...  

AbstractPurposeThe purpose of this prospective study was to investigate the potential of QSM to non-invasively measure hepatic venous oxygen saturation (ShvO2).Materials & MethodsAll animal studies were performed in accordance with the UK Home Office Animals Science Procedures Act (1986) and UK National Cancer Research Institute (NCRI) guidelines. QSM data was acquired from a cohort of mice (n=10) under both normoxic (medical air, 21% O2/ balance N), and hyperoxic conditions (100% O2). Susceptibility measurements were taken from large branches of the portal and hepatic vein under each condition and were used to calculate venous oxygen saturation in each vessel. Blood was extracted from the IVC of three mice under norm- and hyperoxic conditions, and oxygen saturation was measured using a blood gas analyser to act as a gold standard. QSM data was also acquired from a cohort of mice bearing colorectal liver metastases (CRLM). SvO2was calculated from susceptibility measurements made in the portal and hepatic veins, and compared to the healthy animals.ResultsSvO2calculated from QSM measurements showed a significant increase of 14.93% in the portal vein (p < 0.05), and an increase of 21.39% in the hepatic vein (p < 0.01). Calculated results showed excellent agreement with those from the blood gas analyser (26.14% increase). ShvO2was significantly lower in the disease cohort (30.18 ± 11.6%), than the healthy animals (52.67 ± 17.8%) (p < 0.05), but differences in the portal vein were not significant.ConclusionQSM is a feasible tool for non-invasively measuring hepatic venous oxygen saturation and can detect differences in oxygen consumption in livers bearing colorectal metastases.


2021 ◽  
Vol 14 ◽  
pp. 117954762110663
Author(s):  
Masa Abaza ◽  
Sloan E Almehmi ◽  
Ammar Almehmi

Vascular access is the Achilles tendon of hemodialysis and is considered the lifeline for patients with end stage renal disease. Arteriovenous fistulas and grafts are the preferred traditional access for performing dialysis therapy. However, some patients exhaust the traditional routes of dialysis vascular access for different reasons. In search for alternatives, other unusual vascular routes have been explored, such as transhepatic and translumbar approaches, as the last resort to preserve life in this unfortunate population. Here, we present the unusual case of a 66-year-old female who ran out of the traditional vascular access options and became catheter dependent via the right femoral vein. However, due to recurrent femoral catheter infections, extensive skin calciphylactic lesions and her body habitus, other routes were explored and the decision was to use the transhepatic approach. Traditionally, the right and middle hepatic veins are used to insert these catheters. However, the use of the left hepatic vein was not reported in the literature. Hence, in order to avoid the skin lesions seen in our patient, the dialysis catheter was inserted using the left hepatic vein. Overall, this case highlights the challenges of securing a reliable vascular access to perform dialysis therapy and brings attention to other vascular dialysis routes in certain clinical scenarios.


2019 ◽  
Vol 10 (3) ◽  
pp. 330-337
Author(s):  
Christine Montesa ◽  
Tara Karamlou ◽  
Kanishka Ratnayaka ◽  
Stephen G. Pophal ◽  
Justin Ryan ◽  
...  

Background: Patients with heterotaxy, single ventricle and interrupted inferior vena cava are at risk of developing significant pulmonary arteriovenous malformations and cyanosis, and inequitable distribution of hepatic factor has been implicated in their development. We describe our experience with a technique for hepatic vein incorporation that reliably provides resolution of cyanosis and presumably equitable hepatic factor distribution. Methods: A retrospective review of a single-surgeon experience was conducted for patients who underwent this modified Fontan operation utilizing an extracardiac conduit from the hepatic veins to the dominant superior cavopulmonary connection. Preoperative characteristics and imaging, operative details, and postoperative course and imaging were abstracted. Results: Median age at operation was 5 years (2-10 years) and median weight was 19.6 kg (11.8-23 kg). Sixty percent (3/5) of patients had Fontan completion without cardiopulmonary bypass, and follow-up was complete at a median of 14 months (range 1-20 months). Systemic saturations increased significantly from 81% ± 1.9% preoperatively to 95% ± 3.5% postoperatively, P = .0008. Median length of stay was 10 days (range: 7-14 days). No deaths occurred. One patient required reoperation for bleeding and one was readmitted for pleural effusion. Postoperative imaging suggested distribution of hepatic factor to all lung segments with improved pulmonary arteriovenous malformation burden. Conclusions: Hepatic vein incorporation for patients with heterotaxy and interrupted inferior vena cava should optimally provide equitable pulmonary distribution of hepatic factor with resolution of cyanosis. The described technique is performed through a conventional approach, is facile, and improves cyanosis in these complex patients.


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