scholarly journals Non-invasive measurement of hepatic venous oxygen saturation (ShvO2) with quantitative susceptibility mapping in normal mouse liver and livers bearing colorectal metastases

2017 ◽  
Author(s):  
E. Finnerty ◽  
R. Ramasawmy ◽  
J. O’Callaghan ◽  
J. Connell ◽  
M. F. Lythgoe ◽  
...  
Keyword(s):  
Portal Vein ◽  
Oxygen Saturation ◽  
Hepatic Vein ◽  
Animal Studies ◽  
Colorectal Metastases ◽  
Hepatic Veins ◽  
Blood Gas ◽  
National Cancer Research Institute ◽  
Venous Oxygen Saturation ◽  
Hepatic Venous Oxygen Saturation

AbstractPurposeThe purpose of this prospective study was to investigate the potential of QSM to non-invasively measure hepatic venous oxygen saturation (ShvO2).Materials & MethodsAll animal studies were performed in accordance with the UK Home Office Animals Science Procedures Act (1986) and UK National Cancer Research Institute (NCRI) guidelines. QSM data was acquired from a cohort of mice (n=10) under both normoxic (medical air, 21% O2/ balance N), and hyperoxic conditions (100% O2). Susceptibility measurements were taken from large branches of the portal and hepatic vein under each condition and were used to calculate venous oxygen saturation in each vessel. Blood was extracted from the IVC of three mice under norm- and hyperoxic conditions, and oxygen saturation was measured using a blood gas analyser to act as a gold standard. QSM data was also acquired from a cohort of mice bearing colorectal liver metastases (CRLM). SvO2was calculated from susceptibility measurements made in the portal and hepatic veins, and compared to the healthy animals.ResultsSvO2calculated from QSM measurements showed a significant increase of 14.93% in the portal vein (p < 0.05), and an increase of 21.39% in the hepatic vein (p < 0.01). Calculated results showed excellent agreement with those from the blood gas analyser (26.14% increase). ShvO2was significantly lower in the disease cohort (30.18 ± 11.6%), than the healthy animals (52.67 ± 17.8%) (p < 0.05), but differences in the portal vein were not significant.ConclusionQSM is a feasible tool for non-invasively measuring hepatic venous oxygen saturation and can detect differences in oxygen consumption in livers bearing colorectal metastases.

FRACTAL PROPERTIES, SEGMENT ANATOMY, AND INTERDEPENDENCE OF THE HUMAN PORTAL VEIN AND THE HEPATIC VEIN IN 3D

Fractals ◽  
2003 ◽  
Vol 11 (01) ◽  
pp. 53-62 ◽  
Author(s):  
HORST K. HAHN ◽  
CARL J. G. EVERTSZ ◽  
HEINZ-OTTO PEITGEN ◽  
JEAN H. D. FASEL
Keyword(s):  
Portal Vein ◽  
Hepatic Vein ◽  
Three Dimensional ◽  
Branching Ratio ◽  
Liver Parenchyma ◽  
Hepatic Veins ◽  
Scaling Properties ◽  
Computed Tomography Images ◽  
Fractal Properties ◽  
Human Livers

The scaling properties of the portal vein and the hepatic vein are examined, based on three-dimensional computed tomography images of casts of human livers. In particular, a quantitative analysis of the branching ratio based on the Strahler ordering scheme as well as the diameter and length ratios are performed. To quantify the segment anatomy of the liver, the volume of supplied liver parenchyma is measured and related to the corresponding vessel radius. The implications of these findings for segment-oriented liver surgery are discussed. We also investigate the 3D interdependence of the intertwined portal and hepatic veins based on a concept of tree distance that will be introduced.

scholarly journals Arteriovenous Fistula Between the Hepatic Artery and the Hepatic Vein

HPB Surgery ◽  
1989 ◽  
Vol 1 (2) ◽  
pp. 155-160 ◽  
Author(s):  
John M. Howard ◽  
M. Malafa ◽  
Robert J. Coombs ◽  
Anthony M. Iannone
Keyword(s):  
Portal Vein ◽  
Arteriovenous Fistula ◽  
Hepatic Artery ◽  
Hepatic Vein ◽  
Vascular Anomalies ◽  
Celiac Axis ◽  
Hepatic Veins

A patient is presented with multiple vascular anomalies in the branches of the celiac axis as well as in the portal vein and its branches. Apparently, unique in the literature is the presence of a large arteriovenous fistula between the hepatic artery and one of the hepatic veins. The anomalies are presumed to be congenital in origin.

scholarly journals Prediction of Acute Dysfunction of the Liver after Warm Ischemia. Evaluation of Hepatic Venous Oxygen Saturation as an Indicator.

1998 ◽  
Vol 31 (10) ◽  
pp. 2063-2070
Author(s):  
Shunichi Takaya ◽  
Takemi Honma ◽  
Mitsuhiro Sawada ◽  
Naoya Onozuka ◽  
Osamu Harada ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Warm Ischemia ◽  
Venous Oxygen Saturation ◽  
Hepatic Venous Oxygen Saturation

The relationship between mixed venous and regional venous oxygen saturation during cardiopulmonary bypass

Perfusion ◽  
2002 ◽  
Vol 17 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Lena Lindholm ◽  
Vigdis Hansdottir ◽  
Magnus Lundqvist ◽  
Anders Jeppsson
Keyword(s):  
Cardiopulmonary Bypass ◽  
Oxygen Saturation ◽  
Hepatic Vein ◽  
Jugular Vein ◽  
Venous Blood ◽  
Mixed Venous Blood ◽  
Mixed Venous Saturation ◽  
Venous Oxygen Saturation ◽  
The Relationship ◽  
Mixed Venous

The relationship between mixed venous and regional venous saturation during cardiopulmonary bypass (CPB), and whether this relationship is influenced by temperature, has been incompletely elucidated. Thirty patients undergoing valve and/or coronary surgery were included in a prospective, controlled and randomized study. The patients were allocated to two groups: a hypothermic group (28°C) and a tepid group (34°C). Blood gases were analysed in blood from the hepatic vein and the jugular vein and from mixed venous blood collected before surgery, during hypothermia, during rewarming, and 30 min after CPB was discontinued. Oxygen saturation in the hepatic vein was lower than in the mixed venous blood at all times of measurement (-24.0 ± 3.0% during hypothermia, -36.5 ± 2.9% during rewarming, and -30.5 ± 3.0% postoperatively, p < 0.001 at all time points). In 23% of the measurements, the hepatic saturation was < 25% in spite of normal (> 60%) mixed venous saturation. There was a statistical correlation between mixed venous and hepatic vein oxygen saturation (r = 0.76, p < 0.0001). Jugular vein oxygen saturation was lower than mixed venous saturation in all three measurements (-21.6 ± 1.9% during hypothermia, p < 0.001; -16.7 ± 1.9% during rewarming, p < 0.001; and -5.6 ± 2.2% postoperatively, p = 0.037). No significant correlation in oxygen saturation could be detected between mixed venous and jugular vein blood ( r = 0.06, p = 0.65). Systemic temperature did not influence the differences in oxygen saturation between mixed venous and regional venous blood at any time point. In conclusion, regional deoxyge-nation occurs during CPB, in spite of normal mixed venous saturation. Mixed venous oxygen saturation correlates with hepatic, but not with jugular, vein saturation. The level of hypothermia does not influence differences in oxygen saturation between mixed venous and regional venous blood.

CONTINUOUS MONITORING OF HEPATIC VENOUS OXYGEN SATURATION DURING LIVER SURGERY

1989 ◽  
Vol 71 (Supplement) ◽  
pp. A383
Author(s):  
M. Kainuma ◽  
Y. Fujiwara ◽  
A. Shitaokoshi ◽  
Y. Shimada
Keyword(s):  
Oxygen Saturation ◽  
Liver Surgery ◽  
Continuous Monitoring ◽  
Venous Oxygen Saturation ◽  
Hepatic Venous Oxygen Saturation

scholarly journals Reconstruction of the middle hepatic vein using a vein graft from the resected portion of the liver

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
ShiWei Yang ◽  
DongDong Han ◽  
Liang Wang ◽  
Lei Gong ◽  
CanHong Xiang
Keyword(s):  
Portal Vein ◽  
Hepatic Vein ◽  
Intrahepatic Cholangiocarcinoma ◽  
Vein Graft ◽  
Critical Role ◽  
Liver Volume ◽  
Middle Hepatic Vein ◽  
Postoperative Liver Failure ◽  
Hepatic Veins ◽  
Left Hepatectomy

Abstract Background The middle hepatic veins are often infiltrated by intrahepatic cholangiocarcinoma. Reconstruction of the hepatic vein plays a critical role in preserving more of the residual liver volume and reducing the risk of postoperative liver failure in extreme hepatectomy. We here report a novel way to reconstruct middle hepatic vein by using vessel grafts from wasted liver. Case presentation Case 1: A 64-year-old man was diagnosed with intrahepatic cholangiocarcinoma. The bifurcation and left branch of the portal vein were stenosed, and the root of the middle hepatic vein was infiltrated by the tumor. An extended left hepatectomy was performed, the portal vein was resected and reconstructed, and the middle hepatic vein was reconstructed by anastomosing the proximal left hepatic vein to the distal middle hepatic vein. Case 2: A 69-year-old woman was diagnosed with intrahepatic cholangiocarcinoma. The tumor was located in the left lobe of the liver and the left and middle hepatic veins were infiltrated by the tumor. An extended left hepatectomy was performed, and the left portal vein was used as a vein graft to reconstruct the middle hepatic vein. Both of the two patients’ postoperative ultrasound showed vessel graft patency. Conclusion Using a vein graft from the resected portion of the liver to reconstruct the middle hepatic vein was a useful technique and showed good result.

scholarly journals Monitoring of hepatic venous oxygen saturation for predicting acute liver dysfunction after Fontan operations

1994 ◽  
Vol 108 (4) ◽  
pp. 700-708 ◽  
Author(s):  
Hiroshi Takano ◽  
Hikaru Matsuda ◽  
Keishi Kadoba ◽  
Hiroaki Kawata ◽  
Yoshiki Sawa ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Liver Dysfunction ◽  
Venous Oxygen Saturation ◽  
Hepatic Venous Oxygen Saturation

73 MONITORING OF HEPATIC VENOUS OXYGEN SATURATION AFTER LIVER RESECTION

Shock ◽  
1995 ◽  
Vol 3 (5) ◽  
pp. 23
Author(s):  
M. Imhoff ◽  
Ch. Mork ◽  
J. H. Lehner ◽  
D. Löhiein
Keyword(s):  
Liver Resection ◽  
Oxygen Saturation ◽  
Venous Oxygen Saturation ◽  
Hepatic Venous Oxygen Saturation
Sign in / Sign up

Export Citation Format

Share Document