THE EFFICACY OF DEXTRANS OF DIFFERENT MOLECULAR WEIGHTS IN SHOCK SECONDARY TO LIMB CLAMPING

1955 ◽  
Vol 33 (4) ◽  
pp. 553-561
Author(s):  
Lorraine C. Smith ◽  
R. E. Haist
Keyword(s):  
Intrinsic Viscosity ◽  
Fluid Therapy ◽  
Traumatic Shock ◽  
The Body ◽  
Plasma Expander ◽  
Molecular Weights ◽  
Hind Limbs ◽  
Removal Of Metal ◽  
Plasma Expanders

A degree of traumatic shock was produced in rats by the removal of metal clamps which had been applied to both hind limbs for a period of 10 hr. This was lethal within 24 hr. to all animals not receiving fluid therapy. The infusion of plasma expanders delayed or prevented the development of irreversible shock. All fluid therapy relieved the oliguria produced by the shock although this relief generally occurred 24 hr. after the release of the clamps. The plasma expander which best promoted survival was the Connaught dextran 13-1, a solution with an intrinsic viscosity of 0.34 (mean mol. wt. 150,000). Survival with the dextran solutions was increased with increasing molecular weights of the dextrans. This seemed to be related to the retention of the larger molecules for a longer period of time within the body.

THE EFFICACY OF DEXTRANS OF DIFFERENT MOLECULAR WEIGHTS IN SHOCK SECONDARY TO LIMB CLAMPING

1955 ◽  
Vol 33 (1) ◽  
pp. 553-561
Author(s):  
Lorraine C. Smith ◽  
R. E. Haist
Keyword(s):  
Intrinsic Viscosity ◽  
Fluid Therapy ◽  
Traumatic Shock ◽  
The Body ◽  
Plasma Expander ◽  
Molecular Weights ◽  
Hind Limbs ◽  
Removal Of Metal ◽  
Plasma Expanders

A degree of traumatic shock was produced in rats by the removal of metal clamps which had been applied to both hind limbs for a period of 10 hr. This was lethal within 24 hr. to all animals not receiving fluid therapy. The infusion of plasma expanders delayed or prevented the development of irreversible shock. All fluid therapy relieved the oliguria produced by the shock although this relief generally occurred 24 hr. after the release of the clamps. The plasma expander which best promoted survival was the Connaught dextran 13-1, a solution with an intrinsic viscosity of 0.34 (mean mol. wt. 150,000). Survival with the dextran solutions was increased with increasing molecular weights of the dextrans. This seemed to be related to the retention of the larger molecules for a longer period of time within the body.

Sorption of GR-S Type of Polymer on Carbon Black. III. Sorption by Commercial Blacks

1953 ◽  
Vol 26 (1) ◽  
pp. 102-114 ◽  
Author(s):  
I. M. Kolthoff ◽  
R. G. Gutmacher
Keyword(s):  
Molecular Weight ◽  
Carbon Black ◽  
Intrinsic Viscosity ◽  
Benzene Solution ◽  
Weight Fraction ◽  
High Molecular Weight Fraction ◽  
Molecular Weights ◽  
Bound Rubber ◽  
Flow Through ◽  
Peculiar Behavior

Abstract The sorption capacities toward GR-S five commercial carbon blacks are in decreasing order: Spheron-6, Vulcan-1, Philblack-0, Sterling-105, Philblack-A. Apparently, the sorption is not related to surface area. The sorption on Vulcan-1 of GR-S from its solutions in seven different solvents or mixtures of solvents increases with decreasing solvent power for the rubber. The sorption curves of two “cold rubbers,” polymerized at −10 and +5° respectively, showed little difference from that of 50° GR-S. Previous heating of carbon black in nitrogen at 500 or 1100° increased the sorption by about 20 per cent over unheated carbon. Air-heating of carbon black at 425° did not cause a difference in the sorption from benzene solution, but produced an increase in the sorption of rubber from n-heptane solution. In the range 75% butadiene-25% styrene to 5% butadiene-95% styrene, there is practically no effect of the degree of unsaturation on the sorption. Polystyrene of high intrinsic viscosity exhibits a peculiar behavior with furnace blacks. Vulcan-1 sorbed microgel as well as the sol fraction from n-heptane solutions of GR-S containing microgel (conversion 74.7 and 81.5 per cent). There was no appreciable difference in the amount of sorption of rubber fractions having average molecular weights varying from 433,000 to 85,000. There is little change in the amount sorbed after two hours of shaking, but the intrinsic viscosity of the residual rubber decreases with time. The low molecular-weight rubber is sorbed more rapidly, but is slowly replaced by the more tightly sorbed high molecular weight fraction. Partial fractionation of a rubber sample can be achieved by allowing the rubber solution to flow through a column of weakly sorbing carbon black. A large portion of the sorbed rubber can be recovered from the column by washing it with a good solvent such as xylene. Bound rubber is produced by intimate mixing of equal parts of carbon black and rubber swollen in chloroform, when the mixture is dried in vacuum at 80° or at room temperature. Milling is not essential to get bound rubber.

scholarly journals Serum Protein Profile Of Iraqi Hydatidosis Patients with Different Sites of Infection

2007 ◽  
Vol 4 (4) ◽  
pp. 612-616
Author(s):  
Baghdad Science Journal
Keyword(s):  
Serum Protein ◽  
Protein Profile ◽  
The Body ◽  
The Other ◽  
Control Group ◽  
Healthy Individuals ◽  
Banding Patterns ◽  
Blood Samples ◽  
Molecular Weights ◽  
Serum Protein Profile

Blood samples of One hundred and twenty patients from different hospitals in Baghdad infected with hydatidosis in different sites of the body (Liver, Lung, multiorgans and kidney) were collected for this study. On the other hand, 30 healthy individuals were included as a control group. This study was conducted to evaluate the effect of this disease on the serum protein profile of the patients using electrophoresis. The results revealed four different protein banding patterns with difference in number of bands and their molecular weights in comparison to the control group, and these differences depended on the site of infection. However the data showed a presence of the same band in all patients with different site of infection.

First remingtonocetid archaeocete (Mammalia, Cetacea) from the middle Eocene of Egypt with implications for biogeography and locomotion in early cetacean evolution

2015 ◽  
Vol 89 (5) ◽  
pp. 882-893 ◽  
Author(s):  
Ryan M. Bebej ◽  
Iyad S. Zalmout ◽  
Ahmed A. Abed El-Aziz ◽  
Mohammed Sameh M. Antar ◽  
Philip D. Gingerich
Keyword(s):  
Middle Eocene ◽  
Lumbar Vertebrae ◽  
The Body ◽  
Power Stroke ◽  
Tethys Sea ◽  
Vertebral Centra ◽  
Hind Limbs ◽  
Caudal Vertebrae ◽  
Southern Tethys

AbstractRemingtonocetidae are Eocene archaeocetes that represent a unique experiment in cetacean evolution. They possess long narrow skulls, long necks, fused sacra, and robust hind limbs. Previously described remingtonocetids are known from middle Eocene Lutetian strata in Pakistan and India. Here we describe a new remingtonocetid, Rayanistes afer, n. gen. n. sp., recovered from a middle to late Lutetian interval of the Midawara Formation in Egypt. The holotype preserves a sacrum with four vertebral centra; several lumbar and caudal vertebrae; an innominate with a complete ilium, ischium, and acetabulum; and a nearly complete femur. The ilium and ischium of Rayanistes are bladelike, rising sharply from the body of the innominate anterior and posterior to the acetabulum, and the acetabular notch is narrow. These features are diagnostic of Remingtonocetidae, but their development also shows that Rayanistes had a specialized mode of locomotion. The expanded ischium is larger than that of any other archaeocete, supporting musculature for powerful retraction of the hind limbs during swimming. Posteriorly angled neural spines on lumbar vertebrae and other features indicate increased passive flexibility of the lumbus. Rayanistes probably used its enhanced lumbar flexibility to increase the length of the power stroke during pelvic paddling. Recovery of a remingtonocetid in Egypt broadens the distribution of Remingtonocetidae and shows that protocetids were not the only semiaquatic archaeocetes capable of dispersal across the southern Tethys Sea.

Hydrodynamic drag of two frog species: Hymenochirus boettgeri and Rana pipiens

1987 ◽  
Vol 65 (5) ◽  
pp. 1085-1090 ◽  
Author(s):  
Julianna M. Gal ◽  
R. W. Blake
Keyword(s):  
Flow Visualization ◽  
Rana Pipiens ◽  
Swimming Performance ◽  
The Body ◽  
Hydrodynamic Drag ◽  
Subtraction Method ◽  
Flat Plates ◽  
Hind Limbs ◽  
Hymenochirus Boettgeri ◽  
Visualization Experiments

Drag of the aquatic frog Hymenochirus boettgeri was investigated by a series of drop-tank and flow visualization experiments. The maximum drag coefficient (CD) of the body and hind limbs was 0.24–0.11, for a Reynolds number (Re) of 1500–8000. Results of the flow visualization experiment support the CD values obtained for the body and hind limbs of H. boettgeri. CD similarly measured for Rana pipiens was 0.060–0.050, for a Re range of 16 600 – 40 400. A comparison of CD under dynamically similar conditions suggests that jumping may not compromise swimming performance in these two species. CD for the foot of H. boettgeri was examined by three methods: drop-tank experiments with isolated frog's feet and with isolated acetate model feet, and a subtraction method. CD for the isolated foot was 2.5–1.6 for 100 < Re < 700. Results were similar to those obtained with isolated model feet, where 1.8 > CD > 1.2 for 300 < Re < 1300. The subtraction method gave similar results to those obtained from drop-tank experiments with isolated model and real feet, within the Re range of 300–3000. The results of all three methods and flow visualization experiments support the assumption that animal paddles can be treated as three-dimensional flat plates, oriented normal to the direction of flow.

PHYSICOCHEMICAL PROPERTIES OF GLUTEN FROM THREE TYPES OF WHEAT

1964 ◽  
Vol 42 (10) ◽  
pp. 1487-1498 ◽  
Author(s):  
R. R. Matsuo ◽  
A. G. McCalla
Keyword(s):  
Physicochemical Properties ◽  
Intrinsic Viscosity ◽  
Sodium Salicylate ◽  
Soluble Fraction ◽  
Group Analysis ◽  
Performic Acid ◽  
Molecular Weights ◽  
Sodium Chloride Solutions ◽  
Diffusion Constants ◽  
Sulphydryl Groups

Gluten dispersed in 8% sodium salicylate and in lactic acid – sodium chloride solutions yielded intrinsic viscosity values in decreasing order, hard, soft, and durum wheats. Dispersions prepared under nitrogen yielded higher values than those prepared in air. Treatment of gluten with performic acid or with large excesses of sodium sulphite reduced the intrinsic viscosity of all glutens but the order of the values remained the same. Sedimentation coefficients were significantly reduced by the treatments, with the greatest reduction for gluten from durum wheat treated with performic acid. Sulphydryl group analysis gave the lowest value for gluten from hard wheat and the highest for that from durum. Results suggest that disulphide and sulphydryl groups are involved in determining physicochemical properties of gluten.No significant differences among the glutens from the three wheats were found in sedimentation coefficients, in distribution of such coefficients, or in amino acid composition, nor in the diffusion constants or molecular weights for the most soluble fraction from each.

scholarly journals Clinical physiology aspects of chloremia in fluid therapy: a systematic review

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
David Astapenko ◽  
Pavel Navratil ◽  
Jiri Pouska ◽  
Vladimir Cerny
Keyword(s):  
Systematic Review ◽  
Metabolic Acidosis ◽  
Fluid Therapy ◽  
Chloride Content ◽  
The Body ◽  
Infusion Therapy ◽  
Clinical Physiology ◽  
Chloride Homeostasis ◽  
Negative Effect ◽  
Medical Concepts

Abstract Background This systematic review discusses a clinical physiology aspect of chloride in fluid therapy. Crystalloid solutions are one of the most widely used remedies. While generally used in medicine for almost 190 years, studies focused largely on their safety have only been published since the new millennium. The most widely used solution, normal saline, is most often referred to in this context. Its excessive administration results in hyperchloremic metabolic acidosis with other consequences, including higher mortality rates. Methods Original papers and review articles eligible for developing the present paper were identified by searching online in the electronic MEDLINE database. The keywords searched for included hyperchloremia, hypochloremia, and compound words containing the word “chloride,” infusion therapy, metabolic acidosis, renal failure, and review. Results A total of 21,758 papers published before 31 May 2020 were identified; of this number, 630 duplicates were removed from the list. Upon excluding articles based on their title or abstract, 1850 papers were screened, of which 63 full-text articles were assessed. Conclusions According to the latest medical concepts, dyschloremia (both hyperchloremia and hypochloremia) represents a factor indisputably having a negative effect on selected variables of clinical outcome. As infusion therapy can significantly impact chloride homeostasis of the body, the choice of infusion solutions should always take into account the potentially adverse impact of chloride content on chloremia and organ function.

Molecular Weights and Intrinsic Viscosities of Polyisobutylenes

1943 ◽  
Vol 16 (3) ◽  
pp. 493-508
Author(s):  
Paul J. Flory
Keyword(s):  
Molecular Weight ◽  
Intrinsic Viscosity ◽  
Average Molecular Weight ◽  
Chain Structure ◽  
Molecular Weight Range ◽  
Molecular Weights ◽  
Satisfactory Precision ◽  
Heterogeneous Polymers ◽  
Definition Of

Abstract Experimental methods for fractionating polyisobutylene and for determining osmotic pressures have been described. The ratio π/c of osmotic pressure to concentration has been found in the case of cyclohexane solutions of polyisobutylene to vary nonlinearly with concentration, contrary to recent theories advanced by Huggins and the writer. The slope of this relationship appears to be independent of molecular weight. Reliable methods for extrapolating π/c to c=0 have been established, enabling the determination of absolute molecular weights with satisfactory precision up to values of about 1,000,000. Molecular weights of polyisobutylenes calculated from Staudinger's equation are too low; the discrepancy is more than ten-fold at high molecular weights. On the basis of data for carefully fractionated samples covering a two-hundred-fold molecular weight range, the intrinsic viscosity is found to be proportional to the 0.64 power of the molecular weight. This decided deviation from Staudinger's “law”cannot in this instance be attributed to nonlinear chain structure, as Staudinger has sought to do in other cases. This dependence of molecular weight on intrinsic viscosity leads to the definition of a “viscosity average”molecular weight which is obtained when the relationship is applied to heterogeneous polymers. The viscosity average is less than the weight average molecular weight, which would be obtained if Staudinger's equation were applicable, and greater than the number average obtained by osmotic or cryoscopic methods.

Serological responses to Ascaris suum adult worm antigens in Iberian finisher pigs

2003 ◽  
Vol 77 (2) ◽  
pp. 167-172 ◽  
Author(s):  
E. Frontera ◽  
F. Serrano ◽  
D. Reina ◽  
M. Alcaide ◽  
J. Sánchez-López ◽  
...  
Keyword(s):  
Adult Worm ◽  
Body Fluid ◽  
Body Wall ◽  
Ascaris Suum ◽  
The Body ◽  
Enzyme Linked Immunosorbent Assay ◽  
Molecular Weights ◽  
Young Pigs ◽  
Density Values ◽  
Intestinal Worm

AbstractAdult Ascaris suum were dissected to obtain different worm components (body wall, body fluid, ovaries, uterus and oesophagus) which were used as antigens when testing 95 sera of naturally A. suum-infected Iberian pigs by enzyme-linked immunosorbent assay (ELISA) and Western blot (WB). Pigs with patent Ascaris infections had significantly lower ELISA optical density values than pigs without adult worms when using the body fluid and the body wall as antigens. A poor negative correlation was found between adult intestinal worm burden or eggs in faeces and specific antibody responses, measured by ELISA and WB using all antigens. By WB, the recognition of specific bands was variable, but three groups of bands with molecular weights of 97 kDa, 54–58 kDa and 42–44 kDa were generally recognized by sera from naturally infected pigs as well as from hyperimmunized pigs when using the five antigen extracts. The ELISA and WB techniques may be used for immunodiagnosis, using somatic adult worm antigens, to declare young pigs to be Ascaris-free but cannot be used for individual Ascaris-diagnosis in adult Iberian pigs.

scholarly journals Muscular anatomy of the tail of the western grey kangaroo, Macropus fuliginosus

2014 ◽  
Vol 62 (2) ◽  
pp. 166 ◽  
Author(s):  
Rebekah Dawson ◽  
Nick Milne ◽  
Natalie M. Warburton
Keyword(s):  
Body Weight ◽  
The Body ◽  
Functional Roles ◽  
High Speeds ◽  
Hind Limbs ◽  
Grey Kangaroo ◽  
Western Grey Kangaroo ◽  
Low Speeds ◽  
Fifth Limb

The western grey kangaroo, Macropus fuliginosus, is a large-bodied kangaroo that engages in pentapedal locomotion at low speeds and bipedal hopping at high speeds. The tail is thought to have functional roles in both of these modes of locomotion. In pentapedal locomotion the tail acts as a ‘fifth limb’ to support the body weight together with the forelimbs while the hind limbs are drawn forward. The tail has also been suggested to have a role as a counterbalance during bipedal hopping. On the basis of these functional roles for the tail in locomotion, the caudal musculature of the western grey kangaroo was dissected and described in this study. The arrangement of the caudal musculature showed particular adaptations for the role of the tail in both pentapedal locomotion and bipedal hopping.

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