scholarly journals Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD

Thorax ◽  
2004 ◽  
Vol 59 (10) ◽  
pp. 837-842 ◽  
Author(s):  
R A O'Donnell
2014 ◽  
Vol 37 (2) ◽  
pp. 115-120 ◽  
Author(s):  
Artur Niedźwiedź

AbstractEquine Recurrent Airway Obstruction (RAO), also known as heaves or broken wind, is one of the most common disease in middle-aged horses. Inflammation of the airway is inducted by organic dust exposure. This disease is characterized by neutrophilic inflammation, bronchospasm, excessive mucus production and pathologic changes in the bronchiolar walls. Clinical signs are resolved in 3-4 weeks after environmental changes. Horses suffering from RAO are susceptible to allergens throughout their lives, therefore they should be properly managed. In therapy the most importanthing is to eliminate dust exposure, administration of corticosteroids and use bronchodilators to improve pulmonary function.


2020 ◽  
Vol 65 (2) ◽  
pp. 121-131
Author(s):  
Nancy Avila ◽  
Homer Nazeran ◽  
Nelly Gordillo ◽  
Erika Meraz ◽  
Laura Gochicoa

AbstractBackground and objectiveSpirometry, which is the most commonly used technique for asthma diagnosis, is often unsuitable for small children as it requires them to follow exact instructions and perform extreme inspiration and expiration maneuvers. In contrast, impulse oscillometry (IOS) is a child-friendly technique that could serve as an alternative pulmonary function test (PFT) for asthma diagnosis and control in children as it offers several advantages over spirometry. However, the complex test results of IOS may be difficult to be understood by practitioners due to its reliance on mechanical and electrical models of the human pulmonary system. Recognizing this reality, computer-aided decision systems could help to improve the utility of IOS. The main objective of this paper is to understand the current computer-aided classification research works on this topic.MethodsThis paper presents a methodological review of research works related to the computer-aided classification of peripheral airway obstruction using the IOS technique, which is focused on, but not limited to, asthmatic children. Publications that focused on computer-aided classification of asthma, peripheral dysfunction and/or small airway impairment (SAI) based on impulse oscillometric features were selected for this review.ResultsOut of the 34 articles that were identified using the selected scientific web databases and topic-related parameters, only eight met the eligibility criteria. The most relevant results of the articles reviewed are related to the performance of the different classifiers using static features which are solely based on the first pulmonary function testing measurements (IOS and spirometry). These results included an overall classifiers’ accuracy performance ranging from 42.24% to 98.61%.ConclusionThere is still a great opportunity to improve the utility of IOS by developing more computer-aided robust classifiers, specifically for the asthmatic children population as the classification studies performed to date (1) are limited in number, (2) include features derived from tests that are not optimally suitable for children, (3) are solely bi-class (mostly asthma and non-asthma) and therefore fail to include different degrees of peripheral obstruction for disease prevention and control and (4) lack of validation in cases that focus on multi-class classification of the different degrees of peripheral airway obstruction.


1985 ◽  
Vol 9 (9) ◽  
pp. 616-625 ◽  
Author(s):  
W. Hida ◽  
M. Sakurai ◽  
M. Ichinose ◽  
C. Shindoh ◽  
T. Chonan ◽  
...  

JAMA ◽  
1976 ◽  
Vol 235 (3) ◽  
pp. 259 ◽  
Author(s):  
E. R. McFadden

Respirology ◽  
2015 ◽  
Vol 20 (6) ◽  
pp. 975-981 ◽  
Author(s):  
Claude S. Farah ◽  
Laurien A.B. Keulers ◽  
Kate M. Hardaker ◽  
Matthew J. Peters ◽  
Norbert Berend ◽  
...  

2019 ◽  
Vol 13 (3) ◽  
pp. 036002 ◽  
Author(s):  
Silvia Pérez-Bogerd ◽  
Alain Michils ◽  
Andrei Malinovschi ◽  
Alain Van Muylem

2011 ◽  
Vol 169 (4) ◽  
pp. 101-101 ◽  
Author(s):  
C. Sandersen ◽  
D. Olejnik ◽  
T. Franck ◽  
P. Neven ◽  
D. Serteyn ◽  
...  

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