scholarly journals Association between trial registration and positive study findings: cross sectional study (Epidemiological Study of Randomized Trials—ESORT)

BMJ ◽  
2017 ◽  
pp. j917 ◽  
Author(s):  
Ayodele Odutayo ◽  
Connor A Emdin ◽  
Allan J Hsiao ◽  
Mubeen Shakir ◽  
Bethan Copsey ◽  
...  
2019 ◽  
Vol 5 ◽  
pp. 205520761988098
Author(s):  
Renae L Smith-Ray ◽  
Nima Nikzad ◽  
Tanya Singh ◽  
Jenny Z Jiang ◽  
Michael S Taitel ◽  
...  

Objective Many American adults are insufficiently active. Digital health programs are designed to motivate this population to engage in regular physical activity and often rely on wearable devices and apps to objectively measure physical activity for a large number of participants. The purpose of this epidemiological study was to analyze the rates of physical activity among participants in a digital health program. Method We conducted a cross-sectional study of participants enrolled in a digital health program between January 2014 and December 2016. All activity data were objectively collected through wearable devices. Results Participants ( n =  241,013) were on average 39.7 years old and 65.7% were female. Participants walked on average 3.72 miles per day. Overall, 5.3% and 21.8% of participants were being treated with diabetes and cardiovascular medications respectively, but these rates varied across young, middle and older adults. Participants of all ages being treated with cardiovascular and/or diabetes medications walked significantly less than those not being treated for these conditions. Conclusion The feasibility of using a large database containing data from consumer-grade activity trackers was demonstrated through this epidemiological study of physical activity rates across age and condition status of participants. The approach and findings described may inform future research as the information age brings about new opportunities to manage and study massive amounts of data generated by connected devices.


2019 ◽  
Vol 4 (3) ◽  
pp. 168-173
Author(s):  
Koorosh Etemad ◽  
Parto Sabetrasekh ◽  
Shohra Qaderi ◽  
Salman Khazaei ◽  
◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Wangla Ciren ◽  
Qucuo Nima ◽  
Yajie Li ◽  
Ruifeng He ◽  
Deji Suolang ◽  
...  

Abstract Background Obesity, diabetes, and hypertension, as three of the most prevalent chronic diseases, remain a daunting health challenge. However, to our knowledge, no study has made a thorough examination of the association between the three chronic diseases and daytime napping, a widely accepted behavior in many countries. This is especially necessary among Tibetan populations, whose lifestyles and health outcomes may be unique, yet patterns of chronic diseases and napping are under-examined. Thus, we sought to explore the aforementioned association in the Tibetan population of China. Methods A total of 2902 participants aged 45–79 in 2019 were included. Multivariate logistic regressions were conducted in 2020. The sex disparity was examined through interaction and stratified analyses. Results Hypertension (40.7%) was more prevalent than obesity (20.2%) and diabetes (21.6%). Comparing to non-nappers, those who napped were more likely to have any conditions (OR = 1.30, 95% CI = 1.04–1.62 for 1–59 min/day group and OR = 1.40, 95% CI = 1.10–1.80 for ≥60 min/day group). Participants who had 1–59 min/day of napping were more likely to develop obesity (OR = 1.37, 95% CI = 1.07–1.75), and ≥ 60 min/day of napping was associated with diabetes (OR = 1.33, 95% CI = 1.01–1.74). The interactions between napping and sex were not statistically significant in the models. Conclusions The study revealed napping was unfavorably associated with obesity, diabetes, and any conditions in Tibetan people living on the Tibetan Plateau. Future interventions regarding the three chronic diseases may pay more attention to napping. Trial registration Not applicable.


PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0239996
Author(s):  
Kwangtaek Kim ◽  
Leonid Churilov ◽  
Chong Oon Tan ◽  
Tuong Phan ◽  
Jake Geertsema ◽  
...  

A patient’s death can pose significant stress on the family and the treating anaesthetist. Anaesthetists’ attitudes about the benefits of and barriers to attending a patient’s funeral are unknown. Therefore, we performed a prospective, cross-sectional study to ascertain the frequency of anaesthetists’ attendance at a patient’s funeral and their perceptions about the benefits and barriers. The primary aim was to investigate the attitudes of anaesthetists towards attending the funeral of a patient. The secondary aims were to examine the perceived benefits of and barriers to attending the funeral and to explore the rate of bonds being formed between anaesthetists, patients and families. Of the 424 anaesthetists who completed the survey (response rate 21.2%), 25 (5.9%) had attended a patient’s funeral. Of the participants, 364 (85.9%) rarely formed special bonds with patients or their families; 233 (55%) believed that forming a special bond would increase the likelihood of their attendance. Showing respect to patients or their families was the most commonly perceived benefit of attending a funeral. Participants found expression of personal grief and caring for the patient at the end-of-life and beyond beneficial to themselves and the family. Fear of their attendance being misinterpreted or perceived as not warranted by the family as well as time restraints were barriers for their attendance. Most anaesthetists had never attended a patient’s funeral. Few anaesthetists form close relationships with patients or their families. Respect, expression of grief and caring beyond life were perceived benefits of attendance. Families misinterpreting the purpose of attendance or not expecting their attendance and time restraints were commonly perceived barriers. Trial registration: ACTRN 12618000503224.


PLoS ONE ◽  
2019 ◽  
Vol 14 (7) ◽  
pp. e0219458 ◽  
Author(s):  
Jan A. A. van Heteren ◽  
Isabeau van Beurden ◽  
Jeroen P. M. Peters ◽  
Adriana L. Smit ◽  
Inge Stegeman

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