scholarly journals Association between randomised trial evidence and global burden of disease: cross sectional study (Epidemiological Study of Randomized Trials--ESORT)

BMJ ◽  
2015 ◽  
Vol 350 (jan28 24) ◽  
pp. h117-h117 ◽  
Author(s):  
C. A. Emdin ◽  
A. Odutayo ◽  
A. J. Hsiao ◽  
M. Shakir ◽  
S. Hopewell ◽  
...  
BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e040754 ◽  
Author(s):  
Tiffany Renee Phillips ◽  
Christopher Fairley ◽  
Kate Maddaford ◽  
Sabrina Trumpour ◽  
Rebecca Wigan ◽  
...  

ObjectiveTo examine the rinsing and gargling mouthwash practices among frequent mouthwash users to determine if there are differences in use between gender, sexual orientation and sex work status.DesignCross-sectional study.SettingData obtained from patients attending a sexual health centre located in Melbourne, Australia.Participants200 frequent mouthwash users (four or more times per week), 50 for each of the following patient groups: men who have sex with men (MSM), female sex workers (FSW), females who are not sex workers and men who have sex with women only (MSW). Participants were observed and audio recorded using mouthwash.Primary and secondary outcome measuresDescriptive analyses were conducted to calculate the median age, time rinsing and gargling, amount of mouthwash used and proportion of participants who rinsed, gargled or both, as determined from the audio files. Kruskal-Wallis H test and χ2 test were used to examine differences between the patient groups.ResultsMedian age was 28 years (IQR: 24–33). During the study, most (n=127; 63.5%) rinsed and gargled, but 70 (35.0%) rinsed only and three (1.5%) gargled only. Median time rinsing was 13.5 s (IQR: 8.5–22.0 s), gargling was 4.0 s (IQR: 2.5–6.0 s) and the median total duration was 17.0 s (IQR: 11.5–25.8 s). Median duration of mouthwash did not differ significantly between the groups (females not sex workers: 18.8 s (IQR: 12.5–24.5 s); FSW: 14.0 s (9.0–22.0 s); MSM: 22.3 s (13.0–26.5 s); MSW: 15.8 s (12.0–25.0 s); p=0.070) but males used mouthwash longer than females (median 20.3 s compared with 15.5 s; p=0.034). The median volume of mouthwash used was 20 mL (IQR: 15–27 mL). And most (n=198; 99.0%) did not dilute mouthwash with water.ConclusionOver a quarter of frequent users do not gargle mouthwash at all (35%) and used it for a substantially shorter period of time than it was used in the randomised trial (1 min) where it was shown to be effective at inhibiting Neisseria gonorrhoeae growth. Our findings suggest that many frequent mouthwash users do not follow the manufacturer instructions for using mouthwash and may not use mouthwash in a way that was shown to reduce the growth of oropharyngeal gonorrhoea.


2019 ◽  
Vol 5 ◽  
pp. 205520761988098
Author(s):  
Renae L Smith-Ray ◽  
Nima Nikzad ◽  
Tanya Singh ◽  
Jenny Z Jiang ◽  
Michael S Taitel ◽  
...  

Objective Many American adults are insufficiently active. Digital health programs are designed to motivate this population to engage in regular physical activity and often rely on wearable devices and apps to objectively measure physical activity for a large number of participants. The purpose of this epidemiological study was to analyze the rates of physical activity among participants in a digital health program. Method We conducted a cross-sectional study of participants enrolled in a digital health program between January 2014 and December 2016. All activity data were objectively collected through wearable devices. Results Participants ( n =  241,013) were on average 39.7 years old and 65.7% were female. Participants walked on average 3.72 miles per day. Overall, 5.3% and 21.8% of participants were being treated with diabetes and cardiovascular medications respectively, but these rates varied across young, middle and older adults. Participants of all ages being treated with cardiovascular and/or diabetes medications walked significantly less than those not being treated for these conditions. Conclusion The feasibility of using a large database containing data from consumer-grade activity trackers was demonstrated through this epidemiological study of physical activity rates across age and condition status of participants. The approach and findings described may inform future research as the information age brings about new opportunities to manage and study massive amounts of data generated by connected devices.


2016 ◽  
Vol 16 (5) ◽  
pp. 584-591 ◽  
Author(s):  
Chante Karimkhani ◽  
Valentine Wanga ◽  
Luc E Coffeng ◽  
Paria Naghavi ◽  
Robert P Dellavalle ◽  
...  

2019 ◽  
Vol 4 (3) ◽  
pp. 168-173
Author(s):  
Koorosh Etemad ◽  
Parto Sabetrasekh ◽  
Shohra Qaderi ◽  
Salman Khazaei ◽  
◽  
...  

2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Joan Xaveria Mahulae ◽  
Jaslis Ilyas

Abstrak Penelitian yang dilakukan oleh IHME pada tahun 2010 terkait Global Burden of Disease menunjukkan bahwa stroke merupakan penyebab kematian terbesar di Indonesia. Pembiayaan penyakit stroke oleh BPJS Kesehatan menduduki peringkat kedua terbesar setelah penyakit jantung. Penelitian ini ditujukan untuk mengetahui karakteristik dominan yang memicu variasi klaim pasien stroke rawat inap peserta JKN di RS X Sumatera Utara Penelitian ini merupakan penelitian kuantitatif dengan rancangan cross sectional dan analisis multivariat dengan uji regresi linear. Karakteristik yang dominan berhubungan dengan total klaim pasien stroke adalah kelas perawatan (p-value=0,0005), jenis kepesertaan (p-value=0,0005), lama hari rawat (p-value= 0,004), dan tingkat keparahan ( p-value = 0,0005). Abstract Refers to IHME study in 2010 about Global Burden of Disease shows that stroke is one of the highest cause of mortality in Indonesia. While the expenditure by BPJS Health for stroke is the 2nd highest after heart disease. This study aims to determine the most dominant characteristics associated with the total claims of stroke patients covered by JKN for inpatient service at X Hospital by doing multivar­iate analysis with variable linear regression method. The most significant characteristics are type of health care, type of membership, length of stay age, and level of severity. The finding shows that X Hospital is still not optimal in providing services for stroke. Some feasible efforts that can be considered are increasing the neurovascular experts and providing better diagnostic equipments in order to deliver the necessary treatment. 


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