scholarly journals Correlation of immunoglobulin and C reactive protein levels in ankylosing spondylitis and rheumatoid arthritis.

1987 ◽  
Vol 46 (4) ◽  
pp. 273-276 ◽  
Author(s):  
K M Sanders ◽  
A Hertzman ◽  
M R Escobar ◽  
B H Littman
Keyword(s):  
Rheumatoid Arthritis ◽  
Ankylosing Spondylitis ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

scholarly journals Anti-HLA Class II Antibodies Correlate with C-Reactive Protein Levels in Patients with Rheumatoid Arthritis Associated with Interstitial Lung Disease

Cells ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 691
Author(s):  
Alma D. Del Angel-Pablo ◽  
Ivette Buendía-Roldán ◽  
Mayra Mejía ◽  
Gloria Pérez-Rubio ◽  
Karol J. Nava-Quiroz ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Class Ii ◽  
Hla Class Ii ◽  
C Reactive Protein ◽  
Hla Antibodies ◽  
Protein Levels ◽  
Reactive Protein ◽  
Genetic And Environmental Factors

The pathogenesis of Rheumatoid Arthritis (RA) is not fully understood, probably influenced by genetic and environmental factors. Interstitial Lung Disease (ILD) is an extra-articular manifestation of RA, which contributes significantly to morbidity and mortality. The identification of anti-HLA antibodies has been useful in the transplantation field; however, its contribution to autoimmune diseases as RA has not been fully studied. We aimed to determine the presence of anti-HLA antibodies in RA patients with and without ILD and its possible association with clinical and biochemical markers. One-hundred and forty-seven RA patients, of which 65 had ILD (RA-ILD group), were included. Sera samples for Anti-HLA Class II LABScreen panel-reactive antibodies (PRA) were analyzed. In both groups, women predominated, and lung function was worse in patients with ILD. The anti-CCP+ (UI/mL) was higher in the RA group in comparison to RA-ILD (p < 0.001). Expositional risk factors (tobacco smoking and biomass-burning smoke) were higher in RA-ILD patients. PRA+ was identified in ~25% RA-ILD patients, while ~29% in the RA group. The CRP levels have a positive correlation with the percentage of reactivity (%PRA, p = 0.02, r2 = 0.60) in the RA-ILD group. In conclusion, anti-HLA antibodies correlate with C-reactive protein levels in RA patients with ILD.

scholarly journals Relationship between time-integrated C-reactive protein levels and radiologic progression in patients with rheumatoid arthritis

2000 ◽  
Vol 43 (7) ◽  
pp. 1473-1477 ◽  
Author(s):  
Michael J. Plant ◽  
Arnold L. Williams ◽  
Margaret M. O'Sullivan ◽  
Peter A. Lewis ◽  
Edward C. Coles ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Radiologic Progression

Do C-reactive protein levels help predict onset of rheumatoid arthritis in women?

2007 ◽  
Vol 3 (6) ◽  
pp. 318-319
Author(s):  
Dirkjan van Schaardenburg ◽  
Gertjan Wolbink ◽  
Michael T Nurmohamed ◽  
Bernardus AC Dijkmans
Keyword(s):  
Rheumatoid Arthritis ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

scholarly journals Comparative analysis of the systemic inflammatory response in rheumatic diseases

2012 ◽  
Vol 93 (1) ◽  
pp. 12-17
Author(s):  
D V Ivanov ◽  
L A Sokolova ◽  
E Yu Gusev ◽  
L N Kamkina ◽  
N O Plekhanova
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Ankylosing Spondylitis ◽  
Inflammatory Response ◽  
Rheumatic Diseases ◽  
Lupus Erythematosus ◽  
C Reactive Protein ◽  
Systemic Lupus ◽  
Reactive Protein ◽  
Reactivity Coefficient

Aim. To compare the course of chronic systemic inflammation during various rheumatic diseases. Methods. Examined were three groups of patients: with ankylosing spondylitis - 25 people (20 males and 5 females), with rheumatoid arthritis - 26 people (11 males and 15 females) and with systemic lupus erythematosus - 49 people (3 males and 46 females). The control group included 50 practically healthy individuals (26 males and 24 females). Analyzed were the following parameters: the content of interleukin-6, -8, -10, C-reactive protein. The integral index of the reactivity coefficient was calculated. Results. The level of the studied cytokines was significantly higher in systemic lupus erythematosus, than in ankylosing spondylitis and rheumatoid arthritis, while the content of C-reactive protein was significantly higher in ankylosing spondylitis and rheumatoid arthritis. The values of the reactivity coefficient were also significantly higher in systemic lupus erythematosus. Conclusion. The presence of systemic inflammation was determined in most patients with systemic lupus erythematosus, while ankylosing spondylitis and rheumatoid arthritis were characterized only by mild manifestations of systemic inflammatory response.

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