Small Molecule Allosteric Modulation of the Glucagon-Like Peptide-1 Receptor Enhances the Insulinotropic Effect of Oxyntomodulin

2012 ◽  
Vol 82 (6) ◽  
pp. 1066-1073 ◽  
Author(s):  
Francis S. Willard ◽  
Denise Wootten ◽  
Aaron D. Showalter ◽  
Emilia E. Savage ◽  
James Ficorilli ◽  
...  
Keyword(s):  
Small Molecule ◽  
Allosteric Modulation ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1 ◽  
Insulinotropic Effect

scholarly journals Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0154229 ◽  
Author(s):  
Aiysha Thompson ◽  
Jeffrey W. Stephens ◽  
Stephen C. Bain ◽  
Venkateswarlu Kanamarlapudi
Keyword(s):  
Small Molecule ◽  
Molecular Characterisation ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

scholarly journals Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles

2016 ◽  
Vol 291 (20) ◽  
pp. 10700-10715 ◽  
Author(s):  
Ana B. Bueno ◽  
Aaron D. Showalter ◽  
David B. Wainscott ◽  
Cynthia Stutsman ◽  
Aranzazu Marín ◽  
...  
Keyword(s):  
Allosteric Modulation ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

Differential Activation and Modulation of the Glucagon-Like Peptide-1 Receptor by Small Molecule Ligands

2013 ◽  
Vol 83 (4) ◽  
pp. 822-834 ◽  
Author(s):  
Denise Wootten ◽  
Emilia E. Savage ◽  
Francis S. Willard ◽  
Ana B. Bueno ◽  
Kyle W. Sloop ◽  
...  
Keyword(s):  
Small Molecule ◽  
Differential Activation ◽  
Small Molecule Ligands ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1
Sign in / Sign up

Export Citation Format

Share Document