Regulation of Constitutive Mouse Hepatic Cytochromes P450 and Growth Hormone Signaling Components by 3-Methylcholanthrene

2006 ◽  
Vol 34 (9) ◽  
pp. 1530-1538 ◽  
Author(s):  
Chunja Lee ◽  
Janine R. Hutson ◽  
Vivien Kok-Fung Tzau ◽  
David S. Riddick
Keyword(s):  
Growth Hormone ◽  
Cytochromes P450 ◽  
Hormone Signaling ◽  
Signaling Components

Growth hormone signaling and action in obese versus lean human subjects: evidence of increased hepatic GH sensitivity in obesity

2017 ◽  
Author(s):  
Morten Hogild Pedersen ◽  
Ann Mosegaard Bak ◽  
Steen Bonlokke Pedersen ◽  
Niels Jessen ◽  
Niels Moller ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Human Subjects ◽  
Hormone Signaling

scholarly journals Obesity and its impact on COVID-19

2021 ◽  
Author(s):  
Angélica J. M. de Leeuw ◽  
Maureen A. M. Oude Luttikhuis ◽  
Annemarijn C. Wellen ◽  
Christine Müller ◽  
Cornelis F. Calkhoven
Keyword(s):  
Risk Factors ◽  
Growth Hormone ◽  
Healthcare Systems ◽  
Review Literature ◽  
Overweight And Obesity ◽  
Hormone Signaling ◽  
Global Spread ◽  
Number Of Publications ◽  
The Impact ◽  
Sheer Number

AbstractThe severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has proven a challenge to healthcare systems since its first appearance in late 2019. The global spread and devastating effects of coronavirus disease 2019 (COVID-19) on patients have resulted in countless studies on risk factors and disease progression. Overweight and obesity emerged as one of the major risk factors for developing severe COVID-19. Here we review the biology of coronavirus infections in relation to obesity. In particular, we review literature about the impact of adiposity-related systemic inflammation on the COVID-19 disease severity, involving cytokine, chemokine, leptin, and growth hormone signaling, and we discuss the involvement of hyperactivation of the renin-angiotensin-aldosterone system (RAAS). Due to the sheer number of publications on COVID-19, we cannot be completed, and therefore, we apologize for all the publications that we do not cite.

17β-Estradiol positively modulates growth hormone signaling through the reduction of SOCS2 negative feedback in human osteoblasts

Bone ◽  
2013 ◽  
Vol 55 (1) ◽  
pp. 84-92 ◽  
Author(s):  
Simona Bolamperti ◽  
Emanuela Mrak ◽  
GianLuigi Moro ◽  
Paolo Sirtori ◽  
Gianfranco Fraschini ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Negative Feedback ◽  
Hormone Signaling ◽  
Human Osteoblasts ◽  
17Β Estradiol

scholarly journals PIF4 and PIF4-Interacting Proteins: At the Nexus of Plant Light, Temperature and Hormone Signal Integrations

2021 ◽  
Vol 22 (19) ◽  
pp. 10304
Author(s):  
Yang Xu ◽  
Ziqiang Zhu
Keyword(s):  
Target Genes ◽  
High Ambient Temperature ◽  
Interacting Proteins ◽  
Hormone Signaling ◽  
Helix Loop Helix ◽  
Robust Network ◽  
Global Transcriptome ◽  
Signaling Components ◽  
Reduce Gene Expression ◽  
Gene Expression Levels

Basic helix-loop-helix (bHLH) family transcription factor PHYTOCHROME INTERACTING FACTOR 4 (PIF4) is necessary for plant adaption to light or high ambient temperature. PIF4 directly associates with plenty of its target genes and modulates the global transcriptome to induce or reduce gene expression levels. However, PIF4 activity is tightly controlled by its interacting proteins. Until now, twenty-five individual proteins have been reported to physically interact with PIF4. These PIF4-interacting proteins act together with PIF4 and form a unique nexus for plant adaption to light or temperature change. In this review, we will discuss the different categories of PIF4-interacting proteins, including photoreceptors, circadian clock regulators, hormone signaling components, and transcription factors. These distinct PIF4-interacting proteins either integrate light and/or temperature cues with endogenous hormone signaling, or control PIF4 abundances and transcriptional activities. Taken together, PIF4 and PIF4-interacting proteins play major roles for exogenous and endogenous signal integrations, and therefore establish a robust network for plants to cope with their surrounding environmental alterations.

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