In vivo study of partial liver resection on pigs using a 1.9 μm thulium fiber laser

2011 ◽  
Author(s):  
D. Theisen-Kunde ◽  
H. Wolken ◽  
V. Danicke ◽  
R. Brinkmann ◽  
H. Bruch ◽  
...  
Keyword(s):  
Liver Resection ◽  
Fiber Laser ◽  
In Vivo Study ◽  
Partial Liver Resection ◽  
Thulium Fiber Laser

Laparoscopic blood-saving liver resection using a new radiofrequency-assisted device: preliminary report of an in vivo study with pig liver

2008 ◽  
Vol 22 (5) ◽  
pp. 1384-1391 ◽  
Author(s):  
Ana Navarro ◽  
Fernando Burdio ◽  
Enrique J. Berjano ◽  
Antonio Güemes ◽  
Ramón Sousa ◽  
...  
Keyword(s):  
Liver Resection ◽  
Preliminary Report ◽  
In Vivo Study ◽  
Pig Liver

scholarly journals Preliminary Evaluation of Thulium Doped Fiber Laser in Pig Model of Liver Surgery

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Maciej Janeczek ◽  
Jacek Świderski ◽  
Albert Czerski ◽  
Bogusława Żywicka ◽  
Jolanta Bujok ◽  
...  
Keyword(s):  
Liver Resection ◽  
Fiber Laser ◽  
Liver Surgery ◽  
Thermal Damage ◽  
Continuous Wave ◽  
Histopathological Analysis ◽  
Swine Model ◽  
Preliminary Evaluation ◽  
Partial Liver Resection ◽  
Liver Transection

Partial liver resection is a treatment of choice for liver tumors; the range of parenchyma excision varies from a small part of the tissue surrounding the neoplasm up to 70% of the organ. One of the major concerns during liver resection is blood loss. Thulium lasers which are characterized by the length of emission wave corresponding to a peak absorption of water create a new possibility of cutting tissues efficiently with minimal thermal damage and concurrently providing a good hemostasis control. The aim of our study was to evaluate an impact of liver transection with thulium doped fiber laser on an intraoperative bleeding and histopathological changes during postoperative period in swine model. Ten animals were subjected to open surgery partial liver resection and an incision of liver tissue with an all-fiber, diode-pumped, and continuous-wave Tm3+-doped fiber laser emitting 37.4 W of output power at ~1.94 μm wavelength. The macroscopic and histopathological evaluation was performed intraoperatively as well as 7 and 14 days after surgery. Macroscopically almost no bleeding was observed during surgery and no signs of bleeding were stated after 7 and 14 days. Histopathological analysis of the transection margin revealed a thermal damage area ranging in depth from 620.23 ± 23.82 μm on the day of surgery to 1817.70 ± 211.98 μm after 7 days. In the samples taken intraoperatively and after 7 days a superficial zone of carbonization was visibly separated from the deeper changes. After 14 days one 765.35 μm deep zone characterized by a granulation was present. In conclusion, thulium doped fiber laser is efficacious in cutting with a narrow zone of thermal injury and provides a good hemostasis during liver transection, thus being a potential tool for oncotic liver surgery.

Comparison between a 1.92-μm fiber laser and a standard HF-dissection device for nephron-sparing kidney resection in a porcine in vivo study

2011 ◽  
Vol 26 (4) ◽  
pp. 509-514 ◽  
Author(s):  
Dirk Theisen-Kunde ◽  
Sönke Tedsen ◽  
Christian Doehn ◽  
Dieter Jocham ◽  
Ingo Kausch von Schmeling
Keyword(s):  
Fiber Laser ◽  
In Vivo Study ◽  
Nephron Sparing ◽  
Kidney Resection

Time-lag combination therapy for cerebral ischemia using the FNK protein transduction technology and an immunosuppressant, I: In vivo study

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S57-S57
Author(s):  
Ken-ichiro Kasura ◽  
Megumi Watanabe ◽  
Kumiko Takahashi ◽  
Genki Mizukoshi ◽  
Seiji Ohkubo ◽  
...  
Keyword(s):  
Cerebral Ischemia ◽  
Combination Therapy ◽  
Time Lag ◽  
In Vivo Study ◽  
Protein Transduction

321-LB: The Link between Obesity and Changes in Epigenetic Marks in Adipose Tissue—In Vivo Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 321-LB
Author(s):  
ANETA ALAMA ◽  
DOROTA PAWE?KA ◽  
ANETA MYSZCZYSZYN ◽  
MALGORZATA MALODOBRA-MAZUR
Keyword(s):  
Adipose Tissue ◽  
In Vivo Study ◽  
Epigenetic Marks

Growth-promoting effects of diabetes and insulin on arteries. An in vivo study of rat aorta

Diabetes ◽  
1986 ◽  
Vol 35 (9) ◽  
pp. 973-978 ◽  
Author(s):  
L. Capron ◽  
J. Jarnet ◽  
S. Kazandjian ◽  
E. Housset
Keyword(s):  
Rat Aorta ◽  
In Vivo Study ◽  
Growth Promoting
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