Optofluidic ring resonator sensor for sensitive label-free detection of breast cancer antigen CA15-3 in human serum

2009 ◽  
Author(s):  
Hongying Zhu ◽  
Paul S. Dale ◽  
Xudong Fan
Keyword(s):  
Breast Cancer ◽  
Human Serum ◽  
Ring Resonator ◽  
Label Free ◽  
Cancer Antigen ◽  
Label Free Detection

scholarly journals Label-free detection of morpholino-DNA hybridization using a silicon photonics suspended slab micro-ring resonator

2021 ◽  
pp. 1-1
Author(s):  
Soha Yousuf ◽  
Jongmin Kim ◽  
Ajymurat Orozaliev ◽  
Marcus Dahlem ◽  
Yong-Ak Song ◽  
...  
Keyword(s):  
Silicon Photonics ◽  
Dna Hybridization ◽  
Ring Resonator ◽  
Label Free ◽  
Label Free Detection

scholarly journals Label Free Detection of CD4+ and CD8+ T Cells Using the Optofluidic Ring Resonator

Sensors ◽  
2010 ◽  
Vol 10 (6) ◽  
pp. 5798-5808 ◽  
Author(s):  
John T. Gohring ◽  
Xudong Fan
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Ring Resonator ◽  
Label Free ◽  
Label Free Detection

scholarly journals Label-free detection of breast cancer marker HER-2/neu with an acoustic biosensor

2010 ◽  
Vol 5 ◽  
pp. 914-917 ◽  
Author(s):  
Friederike J. Gruhl ◽  
Michael Rapp ◽  
Kerstin Länge
Keyword(s):  
Breast Cancer ◽  
Label Free ◽  
Cancer Marker ◽  
Label Free Detection ◽  
Her 2

scholarly journals Photonic Biosensor for Label-Free Detection Based on Photonic Nanostructures on Si-Waveguide Ring Resonator

2021 ◽  
Vol 6 (1) ◽  
pp. 39
Author(s):  
Hoang Anh Truong ◽  
Yugang Shang ◽  
Shunsuke Abe ◽  
Nobuyuki Matsuda ◽  
Hirohito Yamada
Keyword(s):  
Quality Factor ◽  
Ring Resonator ◽  
Clinical Diagnostics ◽  
Label Free ◽  
Electromagnetic Simulations ◽  
Label Free Detection ◽  
Matter Interaction ◽  
Light Matter Interaction ◽  
Conventional Structure ◽  
Waveguide Ring

A new structure of a micro-ring resonator for label-free biosensing is proposed. The structure includes sidewall-grating Si waveguide and periodical side-blocks that can enhance the light–matter interaction. From the electromagnetic simulations, the proposed structure exhibits a four-fold improvement in terms of sensitivity compared with the conventional structure. Moreover, the quality factor of the proposed structure is not degraded from that of the conventional structure. The improved sensitivity is promising for the detection of nanoparticles that can be applied to the environmental field and clinical diagnostics.

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