Applications of fluorescence spectroscopy and dynamic light scattering in biotechnology of camptothecins: promising anticancer drugs

2003 ◽  
Author(s):  
Stefan Kruszewski ◽  
Thomas G. Burke
2007 ◽  
Vol 119 ◽  
pp. 39-42 ◽  
Author(s):  
Hyo Sim Kang ◽  
Sun Wha Oh ◽  
Young Soo Kang

We prepared various pyrazoline derivatives which possess dimethylamino-, ethoxy-, isopropyl-phenyl ring at the 5-position of pyrazoline. The nanoparticles of pyrazoline derivative ranging from tens to hundreds of nanometers by the reprecipitation method have been successfully prepared and their optical size-dependent properties have been investigated with UV-vis, fluorescence spectroscopy, DLS (Dynamic Light Scattering) and SEM. The size-dependent optical properties of pyrazoline organic nanoparticles have been observed in the order of dimethylamino- > ethoxy- > isopropyl- in electro-donating characters.


2012 ◽  
Vol 10 (4) ◽  
pp. 1338-1348 ◽  
Author(s):  
Anca Rusu Hodorog ◽  
Constanta Ibanescu ◽  
Ioana Moleavin ◽  
Nicolae Hurduc

AbstractThermo-sensitive polymers are of outstanding importance due to their ability to undergo controlled major changes in their properties as a response to minor modifications in temperature. The syntheses of novel polymers by grafting polysiloxane containing chlorobenzyl groups in the side chain by the homopolymerization of N,N′-dimethyl acrylamide (DMA) or the copolymerization of DMA and methyl methacrylate (MMA) using SET-LRP technique are presented. The polymers were characterized by 1H-NMR, UV, and fluorescence spectroscopy, and DSC. The thermo-sensitivity and the lower critical solution temperature (LCST), as well as the aggregation phenomena during the phase transition are evidenced by dynamic light scattering (DLS) and rheology.


RSC Advances ◽  
2016 ◽  
Vol 6 (87) ◽  
pp. 83916-83925 ◽  
Author(s):  
Pabitra Maity ◽  
Baishakhi Saha ◽  
Gopinatha Suresh Kumar ◽  
Sanat Karmakar

We have systematically investigated the effect of counterions on the interaction of the Na+ ion with phospholipid membranes using dynamic light scattering, zeta potential, isothermal titration calorimetry and fluorescence spectroscopy techniques.


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