Image data-driven thermal dose prediction for microwave ablation therapy

Author(s):  
Alice K. Ding ◽  
Jon S. Heiselman ◽  
Michael I. Miga
2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
R. Ortega-Palacios ◽  
C. J. Trujillo-Romero ◽  
M. F. J. Cepeda Rubio ◽  
A. Vera ◽  
L. Leija ◽  
...  

Microwave ablation (MWA) by using coaxial antennas is a promising alternative for breast cancer treatment. A double short distance slot coaxial antenna as a newly optimized applicator for minimally invasive treatment of breast cancer is proposed. To validate and to analyze the feasibility of using this method in clinical treatment, a computational model, phantom, and breast swine in vivo experimentation were carried out, by using four microwave powers (50 W, 30 W, 20 W, and 10 W). The finite element method (FEM) was used to develop the computational model. Phantom experimentation was carried out in breast phantom. The in vivo experimentation was carried out in a 90 kg swine sow. Tissue damage was estimated by comparing control and treated micrographs of the porcine mammary gland samples. The coaxial slot antenna was inserted in swine breast glands by using image-guided ultrasound. In all cases, modeling, in vivo and phantom experimentation, and ablation temperatures (above 60°C) were reached. The in vivo experiments suggest that this new MWA applicator could be successfully used to eliminate precise and small areas of tissue (around 20–30 mm2). By modulating the power and time applied, it may be possible to increase/decrease the ablation area.


2015 ◽  
Vol 3 ◽  
pp. 3521-3528 ◽  
Author(s):  
Alexander Piazza ◽  
Christian Zagel ◽  
Sebastian Huber ◽  
Matthias Hille ◽  
Freimut Bodendorf

Volume 4 ◽  
2004 ◽  
Author(s):  
Ashvinikumar V. Mudaliar ◽  
Elaine P. Scott

Radio-frequency (RF) ablation is one of the most widely used methods for the treatment of hepatic malignancies. A finite element method (FEM) analysis was employed to determine the thermal dose delivered to the tumor/tissue region. We simulated heating within a RF probe implanted in generic tumor surrounded by healthy tissue using ANSYS. The 3-D model consists of a tumor / tissue region into which the RF probe is embedded inside the tumor. One-quarter symmetry was then invoked. The blood flow was modeled using Penne’s bio-heat transfer equation with differing perfusion rates between the healthy tissue and tumor volume based on literature values. The resulting temperature distribution throughout the region was determined over time. A program was written in Visual Basic to extract the temperature distribution data in the tumor/tissue region and calculate the thermal dose throughout the region. This was done by using a time–temperature Arrhenius relationship for chemical and physical rate process. Tissue necrosis is assumed complete when a thermal dose of one hour has been achieved at 43 °C. In the present study, the geometry of the electrode had a significant effect on the size of the volume of necrosis. It was found that the lower portion of the tumor did not receive the specified thermal dose relative to the upper portion of the tumor in single setting during the RF ablation therapy. This might be due to the Ni-Ti electrode, which protruded only from the top surface of the trocar. The effectiveness of the existing probe can be improved by having one more set of electrodes protruding out from the lower curved surface of the trocar. It was found that the modified probe significantly improved heating in the lower portion of tumor/tissue area, providing more symmetry between the upper and lower portion.


2010 ◽  
Vol 24 (12) ◽  
pp. 1903-1908 ◽  
Author(s):  
Karim Bensalah ◽  
Altug Tuncel ◽  
Willard Hanson ◽  
Joshua Stern ◽  
Bumsoo Han ◽  
...  

2010 ◽  
Vol 115 (6) ◽  
pp. 962-974 ◽  
Author(s):  
G. Carrafiello ◽  
M. Mangini ◽  
I. De Bernardi ◽  
F. Fontana ◽  
G. Dionigi ◽  
...  

Radiology ◽  
2011 ◽  
Vol 261 (2) ◽  
pp. 643-651 ◽  
Author(s):  
Thomas J. Vogl ◽  
Nagy N. N. Naguib ◽  
Tatjana Gruber-Rouh ◽  
Karen Koitka ◽  
Thomas Lehnert ◽  
...  

2020 ◽  
Vol 67 (6) ◽  
pp. 1548-1557
Author(s):  
Jarrod A. Collins ◽  
Jon S. Heiselman ◽  
Logan W. Clements ◽  
Jared A. Weis ◽  
Daniel B. Brown ◽  
...  

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