In vivo cuticle intact Drosophila mushroom body imaging using laser scanning optical resolution photoacoustic microscopy (Conference Presentation)

2020 ◽  
Author(s):  
Kai-Yao Chang ◽  
Wen-Hung Shih ◽  
Shun-Chi Wu ◽  
Kwok Ho Lam ◽  
Yen-Yin Lin ◽  
...  
Keyword(s):  
Mushroom Body ◽  
Laser Scanning ◽  
Optical Resolution ◽  
Photoacoustic Microscopy ◽  
Body Imaging

Laser-scanning optical-resolution photoacoustic microscopy

2009 ◽  
Vol 34 (12) ◽  
pp. 1771 ◽  
Author(s):  
Zhixing Xie ◽  
Shuliang Jiao ◽  
Hao F. Zhang ◽  
Carmen A. Puliafito
Keyword(s):  
Laser Scanning ◽  
Optical Resolution ◽  
Photoacoustic Microscopy

scholarly journals Deep-learning-based motion-correction algorithm in optical resolution photoacoustic microscopy

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Xingxing Chen ◽  
Weizhi Qi ◽  
Lei Xi
Keyword(s):  
Deep Learning ◽  
Optical Resolution ◽  
Motion Artifacts ◽  
Photoacoustic Microscopy ◽  
Simulation Studies ◽  
Correction Algorithm ◽  
Brain Vessels ◽  
Capillary Networks ◽  
Motion Corrections

Abstract In this study, we propose a deep-learning-based method to correct motion artifacts in optical resolution photoacoustic microscopy (OR-PAM). The method is a convolutional neural network that establishes an end-to-end map from input raw data with motion artifacts to output corrected images. First, we performed simulation studies to evaluate the feasibility and effectiveness of the proposed method. Second, we employed this method to process images of rat brain vessels with multiple motion artifacts to evaluate its performance for in vivo applications. The results demonstrate that this method works well for both large blood vessels and capillary networks. In comparison with traditional methods, the proposed method in this study can be easily modified to satisfy different scenarios of motion corrections in OR-PAM by revising the training sets.

scholarly journals Dual-Polarized Fiber Laser Sensor for Photoacoustic Microscopy

Sensors ◽  
2019 ◽  
Vol 19 (21) ◽  
pp. 4632 ◽  
Author(s):  
Lin ◽  
Liang ◽  
Jin ◽  
Wang
Keyword(s):  
Fiber Laser ◽  
Optical Resolution ◽  
High Sensitivity ◽  
Low Noise ◽  
Laser Sensor ◽  
Photoacoustic Microscopy ◽  
Label Free ◽  
Laser Sensors ◽  
Dual Polarized

Optical resolution photoacoustic microscopy (OR-PAM) provides high-resolution, label-free and non-invasive functional imaging for broad biomedical applications. Dual-polarized fiber laser sensors have high sensitivity, low noise, a miniature size, and excellent stability; thus, they have been used in acoustic detection in OR-PAM. Here, we review recent progress in fiber-laser-based ultrasound sensors for photoacoustic microscopy, especially the dual-polarized fiber laser sensor with high sensitivity. The principle, characterization and sensitivity optimization of this type of sensor are presented. In vivo experiments demonstrate its excellent performance in the detection of photoacoustic (PA) signals in OR-PAM. This review summarizes representative applications of fiber laser sensors in OR-PAM and discusses their further improvements.

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