UV imaging detectors with high performance microchannel plates

2019 ◽  
Author(s):  
Oswald H. W. Siegmund ◽  
John V. Vallerga ◽  
Nathan T. Darling ◽  
Travis L. Curtis ◽  
Jason B. McPhate ◽  
...  
Keyword(s):  
High Performance ◽  
Uv Imaging ◽  
Microchannel Plates ◽  
Imaging Detectors

Development of UV imaging detectors with atomic layer deposited microchannel plates and cross strip readouts

2020 ◽  
Author(s):  
Oswald H. W. Siegmund ◽  
Jason McPhate ◽  
Travis Curtis ◽  
Nathan Darling ◽  
John Vallerga ◽  
...  
Keyword(s):  
Atomic Layer ◽  
Uv Imaging ◽  
Microchannel Plates ◽  
Imaging Detectors

Opaque gallium nitride photocathodes in UV imaging detectors with microchannel plates

2013 ◽  
Author(s):  
Anton S. Tremsin ◽  
Jeffrey S. Hull ◽  
Oswald H. W. Siegmund ◽  
Jason B. McPhate ◽  
John V. Vallerga ◽  
...  
Keyword(s):  
Gallium Nitride ◽  
Uv Imaging ◽  
Microchannel Plates ◽  
Imaging Detectors

scholarly journals Monitoring of Antimicrobial Drug Chloramphenicol Release from Electrospun Nano- and Microfiber Mats using UV Imaging and Bacterial Bioreporters

Pharmaceutics ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 487 ◽  
Author(s):  
Preem ◽  
Bock ◽  
Hinnu ◽  
Putrinš ◽  
Sagor ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Bacterial Infections ◽  
High Performance ◽  
Model Systems ◽  
Local Drug Delivery ◽  
Imaging Method ◽  
Release Behavior ◽  
Buffer Solution ◽  
Uv Imaging

New strategies are continuously sought for the treatment of skin and wound infections due to increased problems with non-healing wounds. Electrospun nanofiber mats with antibacterial agents as drug delivery systems provide opportunities for the eradication of bacterial infections as well as wound healing. Antibacterial activities of such mats are directly linked with their drug release behavior. Traditional pharmacopoeial drug release testing settings are not always suitable for analyzing the release behavior of fiber mats intended for the local drug delivery. We tested and compared different drug release model systems for the previously characterized electrospun chloramphenicol (CAM)-loaded nanofiber (polycaprolactone (PCL)) and microfiber (PCL in combination with polyethylene oxide) mats with different drug release profiles. Drug release into buffer solution and hydrogel was investigated and drug concentration was determined using either high-performance liquid chromatography, ultraviolet-visible spectrophotometry, or ultraviolet (UV) imaging. The CAM release and its antibacterial effects in disc diffusion assay were assessed by bacterial bioreporters. All tested model systems enabled to study the drug release from electrospun mats. It was found that the release into buffer solution showed larger differences in the drug release rate between differently designed mats compared to the hydrogel release tests. The UV imaging method provided an insight into the interactions with an agarose hydrogel mimicking wound tissue, thus giving us information about early drug release from the mat. Bacterial bioreporters showed clear correlations between the drug release into gel and antibacterial activity of the electrospun CAM-loaded mats.

Synthesis of large-area 2D WS2 films and fabrication of a heterostructure for self-powered ultraviolet photodetection and imaging applications

2019 ◽  
Vol 7 (39) ◽  
pp. 12121-12126 ◽  
Author(s):  
Zhihui Zhao ◽  
Di Wu ◽  
Jiawen Guo ◽  
Enping Wu ◽  
Cheng Jia ◽  
...  
Keyword(s):  
High Performance ◽  
Large Area ◽  
Uv Photodetector ◽  
Imaging Capability ◽  
Uv Imaging ◽  
Self Powered

High-performance self-powered ultraviolet (UV) photodetector based on a WS2/GaN heterojunction was demonstrated, which exhibits excellent UV photoresponse properties. Significantly, this photodetector has exhibited excellent UV imaging capability.

scholarly journals Genotyping Energy-Transfer-Cassette-labeled Short-Tandem-Repeat Amplicons with Capillary Array Electrophoresis Microchannel Plates

2001 ◽  
Vol 47 (9) ◽  
pp. 1614-1621 ◽  
Author(s):  
Igor L Medintz ◽  
Lorenzo Berti ◽  
Charles A Emrich ◽  
Jennifer Tom ◽  
James R Scherer ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Genetic Analysis ◽  
High Throughput ◽  
High Performance ◽  
Microchannel Plate ◽  
Str Analysis ◽  
Capillary Array Electrophoresis ◽  
Microchannel Plates ◽  
Capillary Array ◽  
Short Tandem

Abstract Background: Genetic analysis of microsatellite DNA is a powerful tool used in linkage analysis, gene mapping, and clinical diagnosis. To address the expanding needs of studies of short tandem repeats (STRs), we demonstrated high-performance STR analysis on a high-throughput microchannel plate-based platform. Methods: Energy-transfer-cassette-labeled STR amplicons were separated and typed on a microfabricated 96-channel radial capillary array electrophoresis (CAE) microchannel plate system. Four-color detection was accomplished with a laser-excited confocal fluorescence rotary scanner. Results: Multiplex STR analysis with single base-pair resolution was demonstrated on denaturing polyacrylamide gel media. The high-throughput multiplex capabilities of this genetic analysis platform were demonstrated by the simultaneous separation of STR amplicons representing 122 samples in ninety-six 5.5-cm-long channels in <8 min. Sizing values obtained for these amplicons on the CAE microchannel plate were comparable to those measured on a conventional commercial CAE instrument and exhibit <1% sizing variance. Conclusions: Energy-transfer-cassette labeling and microfabricated CAE microchannel plates allow high-performance multiplex STR analyses.

High performance x-ray imaging detectors on foil using solution-processed organic photodiodes with extremely low dark leakage current (Presentation Recording)

2015 ◽  
Author(s):  
Abhishek Kumar ◽  
Date Moet ◽  
Jan Laurens van der Steen ◽  
Albert van Breemen ◽  
Santhosh Shanmugam ◽  
...  
Keyword(s):  
Leakage Current ◽  
High Performance ◽  
Solution Processed ◽  
X Ray ◽  
X Ray Imaging ◽  
Imaging Detectors
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