scholarly journals Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test

2019 ◽  
Author(s):  
Dmitry Stavtsev ◽  
Mikhail Volkov ◽  
Nikita Margaryants ◽  
Andrey Potemkin ◽  
Viktor Dremin ◽  
...  
Keyword(s):  
Rheumatic Diseases ◽  
Laser Doppler Flowmetry ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Laser Doppler ◽  
Doppler Flowmetry ◽  
Pressor Test ◽  
Blood Microcirculation

scholarly journals STUDY OF HEMOMICROCIRCULATION IN UPPER- EXTREMITYSKIN IN HEALTHY MEN IN NORMAL CONDITIONS WITH ACCOUNT OF H

2020 ◽  
Vol 10 (4) ◽  
pp. 63-65
Author(s):  
Vadim Astashov ◽  
Valentin Kozlov ◽  
Victor Sidorov, ◽  
Mihail Uloga ◽  
Inna Borodina ◽  
...  
Keyword(s):  
Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Peripheral Blood ◽  
Upper Extremities ◽  
Laser Doppler ◽  
Peripheral Blood Flow ◽  
Doppler Flowmetry ◽  
Healthy Men ◽  
Young Males ◽  
Blood Microcirculation

In this study we used laser doppler flowmetry to investigate the parameters of peripheral blood flow in the upper extremities in young males both right- and left-handers. Based on the data obtained we found that in right-handers (dextrals) active mechanisms of regulation of blood microcirculation prevail on the leading hand, In left-handers (sinestrals) active and passive mechanisms of its regulation are involved in the regulation of blood flow on the leading hand (left) and on the opposite (right). However, the contribution of active mechanisms is lower than that of right-handers.

Evaluation of blood microcirculation parameters by combined use of laser Doppler flowmetry and videocapillaroscopy methods

2017 ◽  
Author(s):  
M. V. Volkov ◽  
D. A. Kostrova ◽  
N. B. Margaryants ◽  
I. P. Gurov ◽  
N. P. Erofeev ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Doppler Flowmetry ◽  
Blood Microcirculation ◽  
Combined Use

scholarly journals Detection of angiospastic disorders in the microcirculatory bed using laser diagnostics technologies

2017 ◽  
Vol 11 (01) ◽  
pp. 1750016 ◽  
Author(s):  
Irina N. Makovik ◽  
Andrey V. Dunaev ◽  
Victor V. Dremin ◽  
Alexander I. Krupatkin ◽  
Viktor V. Sidorov ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Diagnostic Criteria ◽  
Functional State ◽  
Laser Diagnostics ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Noninvasive Methods ◽  
Doppler Flowmetry ◽  
Microcirculatory Bed ◽  
Pressor Test

The evaluation of the microcirculatory bed functional state and the identification of angiospastic disorders with related complications, when the pathological changes are reversible, have an important role in medical practice. The aim of this study was to evaluate the possibility of using optical noninvasive methods and the cold pressor test to solve this problem.A total of 33 patients with rheumatological diseases and 32 healthy volunteers were included in the study. Laser Doppler flowmetry, tissue reflectance oximetry and pulse oximetry were used as optical noninvasive methods. The parameters were recorded before, immediately after and 20[Formula: see text]min after the cold pressor test. Based on the measured parameters, the complex parameters of the microcirculatory bed were calculated.A detailed statistical analysis of the parameter changes for each individual in the two groups displayed diverse microcirculatory bed parameter responses upon cold exposure, with differing recovery of parameters after CPT. New diagnostic criteria were proposed for the identification of angiospastic disorders. According to the proposed criteria, 27 people of the volunteers group were confirmed to not display any disorders. In the patient group, however, 18 people were observed to have a relatively normal functional state of the microcirculatory bed, while 15 people were observed to have a possible tendency to angiospasm. To highlight the differences between a relatively normal state and presence of angiospastic disorders, statistical analysis of experimental data was carried out, which revealed significant differences. Further analysis of data with angiospastic disorders identified a relationship between their diagnoses and the results of laboratory studies.Thus, the evaluation of combined noninvasive optical diagnostic method use, the cold pressor test and proposed diagnostic criteria showed a positive result. This approach can be used to detect the presence of possible angiospastic disorders and related complications, as well as microcirculatory bed disorders against the background of other diseases.

scholarly journals Wearable Laser Doppler Flowmetry Sensor: A Feasibility Study with Smoker and Non-Smoker Volunteers

Biosensors ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 201
Author(s):  
Mou Saha ◽  
Viktor Dremin ◽  
Ilya Rafailov ◽  
Andrey Dunaev ◽  
Sergei Sokolovski ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Blood Circulation ◽  
Blood Perfusion ◽  
Pulse Frequency ◽  
Laser Doppler ◽  
Doppler Flowmetry ◽  
Left Hand ◽  
Non Invasive ◽  
Blood Microcirculation ◽  
Left Middle

Novel, non-invasive wearable laser Doppler flowmetry (LDF) devices measure real-time blood circulation of the left middle fingertip and the topside of the wrist of the left hand. The LDF signals are simultaneously recorded for fingertip and wrist. The amplitude of blood flow signals and wavelet analysis of the signal are used for the analysis of blood perfusion parameters. The aim of this pilot study is to validate the accuracy of blood circulation measurements recorded by one such non-invasive wearable LDF device for healthy young non-smokers and smokers. This study reveals a higher level of blood perfusion in the non-smoker group compared to the smoker group and vice-versa for the variation of pulse frequency. This result can be useful to assess the sensitivity of the wearable LDF sensor in determining the effect of nicotine for smokers as compared to non-smokers and also the blood microcirculation in smokers with different pathologies.

Method of using laser doppler flowmetry in assessment of the state of blood microcirculation system

2020 ◽  
Author(s):  
Viacheslav V. Osadchyi ◽  
Tatiana I. Stanishevska ◽  
Oksana I. Gorna ◽  
Roman М. Gorbatiuk ◽  
Irina M. Melnychuk ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
The State ◽  
Laser Doppler ◽  
Doppler Flowmetry ◽  
Blood Microcirculation

He-Ne laser effects on blood microcirculation during wound healing: A method of in vivo study through laser Doppler flowmetry

2004 ◽  
Vol 35 (5) ◽  
pp. 363-368 ◽  
Author(s):  
Silvia Cristina Núñez ◽  
Gessé E.C. Nogueira ◽  
Martha S. Ribeiro ◽  
Aguinaldo S. Garcez ◽  
José L. Lage-Marques
Keyword(s):  
Wound Healing ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
In Vivo Study ◽  
Doppler Flowmetry ◽  
Blood Microcirculation

scholarly journals USAGE OF LASER DOPPLER FLOWMETRY FOR CHILDREN BLOOD MICROCIRCULATION ASSESSMENT

2011 ◽  
Vol 1 (1) ◽  
Author(s):  
І. П. Аносов ◽  
Л. В. Антоновська ◽  
О. І. Горна ◽  
Т. І. Станішевська ◽  
Л. М. Маньковська ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Doppler Flowmetry ◽  
Blood Microcirculation

The response of skin perfusion and of rheological and immunological variables to intravenous prostanoid administration in Raynaud’s phenomenon secondary to collagenosis

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 243-249 ◽  
Author(s):  
Drinda ◽  
Neumann ◽  
Pöhlmann ◽  
Vogelsang ◽  
Stein ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Plasma Viscosity ◽  
Laser Doppler ◽  
Erythrocyte Aggregation ◽  
Control Group ◽  
Long Term Effects ◽  
Doppler Flowmetry

Background: Prostanoids are used in the treatment of Raynaud’s phenomenon and acral perfusion disorders secondary to collagenosis. In subjective terms, intravenous administration of these agents produces success in more than 50% of patients. The therapeutic outcome of clinical administration of alprostadil or iloprost may vary from individual to individual. Patients and methods: The following variables were analysed in a cross-over study in 27 patients with collagenosis and Raynaud’s phenomenon: plasma viscosity and erythrocyte aggregation (rheological variables), partial pressure of oxygen and laser Doppler flowmetry in the finger region, and lymphocyte phenotyping and interleukin (IL) determinations (immunological variables). Results: Laser Doppler flowmetry revealed significant differences between patients with secondary Raynaud’s phenomenon and a control group of 25 healthy subjects. Laser Doppler readings did not change significantly as a result of the treatments. Therapy with iloprost produced a reduction in IL-1beta, L-selectin (CD 62 L) and IL-6. Conclusion: The change in immunological variables due to iloprost may explain the long-term effects of prostaglandins in the treatment of Raynaud’s phenomenon. From our results it is not possible to infer any preference for iloprost or alprostadil.

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