Method of using laser doppler flowmetry in assessment of the state of blood microcirculation system

Author(s):  
Viacheslav V. Osadchyi ◽  
Tatiana I. Stanishevska ◽  
Oksana I. Gorna ◽  
Roman М. Gorbatiuk ◽  
Irina M. Melnychuk ◽  
...  
Author(s):  
Хамди Кхаем ◽  
Елена Гортинская

A laser Doppler flowmetry study of the state of the micro­vasculature of the skin in patients with rosacea was per­formed. The amplitude-frequency criteria for assessing dermal circulation are determined. Depth and direction of vascularization disorders are shown. It is proved that the amplitude-frequency characteristic of the state of the micro­vasculature of the skin should be taken into account when choosing the means of therapeutic correction and can serve as one of the criteria for the effectiveness of treatment.


2017 ◽  
Vol 16 (4) ◽  
pp. 60-64
Author(s):  
A. A. Blazhko ◽  
I. I. Shakhmatov ◽  
V. I. Kiselev ◽  
N. A. Lycheva ◽  
S. V. Moskalenko

Introduction. A considerable physical load can lead to the damage of various organs and systems including the system of the microcirculatory bloodstream. Materials and methods. The experimental groups of animals were exposed to 4-hour and 8-hour physical load. The state of the microcirculatory bloodstream was examined by means of laser Doppler flowmetry. Results. 4-hour physical load did not cause any reduction of the microcirculation parameter in rats. 8-hour physical load led to a decrease of the microcirculation parameter and further reduction of flux parameter. Conclusions. Such changes of microcirculation parameters can be one of the symptoms of development of the state of thrombotic readiness and high risk of thrombosis in rats after 8-hour physical load.


2020 ◽  
Vol 10 (4) ◽  
pp. 63-65
Author(s):  
Vadim Astashov ◽  
Valentin Kozlov ◽  
Victor Sidorov, ◽  
Mihail Uloga ◽  
Inna Borodina ◽  
...  

In this study we used laser doppler flowmetry to investigate the parameters of peripheral blood flow in the upper extremities in young males both right- and left-handers. Based on the data obtained we found that in right-handers (dextrals) active mechanisms of regulation of blood microcirculation prevail on the leading hand, In left-handers (sinestrals) active and passive mechanisms of its regulation are involved in the regulation of blood flow on the leading hand (left) and on the opposite (right). However, the contribution of active mechanisms is lower than that of right-handers.


2017 ◽  
Author(s):  
M. V. Volkov ◽  
D. A. Kostrova ◽  
N. B. Margaryants ◽  
I. P. Gurov ◽  
N. P. Erofeev ◽  
...  

Biosensors ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 201
Author(s):  
Mou Saha ◽  
Viktor Dremin ◽  
Ilya Rafailov ◽  
Andrey Dunaev ◽  
Sergei Sokolovski ◽  
...  

Novel, non-invasive wearable laser Doppler flowmetry (LDF) devices measure real-time blood circulation of the left middle fingertip and the topside of the wrist of the left hand. The LDF signals are simultaneously recorded for fingertip and wrist. The amplitude of blood flow signals and wavelet analysis of the signal are used for the analysis of blood perfusion parameters. The aim of this pilot study is to validate the accuracy of blood circulation measurements recorded by one such non-invasive wearable LDF device for healthy young non-smokers and smokers. This study reveals a higher level of blood perfusion in the non-smoker group compared to the smoker group and vice-versa for the variation of pulse frequency. This result can be useful to assess the sensitivity of the wearable LDF sensor in determining the effect of nicotine for smokers as compared to non-smokers and also the blood microcirculation in smokers with different pathologies.


2004 ◽  
Vol 35 (5) ◽  
pp. 363-368 ◽  
Author(s):  
Silvia Cristina Núñez ◽  
Gessé E.C. Nogueira ◽  
Martha S. Ribeiro ◽  
Aguinaldo S. Garcez ◽  
José L. Lage-Marques

Author(s):  
І. П. Аносов ◽  
Л. В. Антоновська ◽  
О. І. Горна ◽  
Т. І. Станішевська ◽  
Л. М. Маньковська ◽  
...  

Author(s):  
Z. Shaienko

Currently, the problem of diabetes mellitus (DM) is one of the most important medical and social challenges worldwide. This is primarily due to the widespread prevalence of the disease and tendency to further increase in the incidence of diabetes mellitus.Systemic microcirculatory disorders play an impor­tant role in the pathogenesis of DM complications. They lead to the development of microangiopathy and neuropathy through the primary lesion of vessels involved in the blood supply of the peripheral parts of the nervous system. Currently, less than one-third of physicians recognize signs of peripheral neuropathy associated with diabetes. Untimely diagnosis contributes significantly to high morbidity, disability, and mortality.The authorinvestigates the experience of the use of laser Doppler flowmetry (LDF) in clinical practice as a method of studying the state of the microcirculatory bed in patients with diabetes mellitus.LDF is a non-invasive quantitative method of microcirculation assessment; its capabilities include the analysis of microcirculatory rhythms and functional testing with different types of provocative effects, which provides with investigating the state of regulatory mechanisms of microcirculation. The prevention and treatment of various microcirculatory disorders is one of the most important problems of medical practice. The difficulties of studying the microcirculation are caused by the very small size of microvessels and strong ramification of intra-organic vascular networks. The use of LDF in scientific research will make it possible toreveal the DM-specific changes in microcir­culatory bed functioning. The findings of some studies suggest that microcirculatory disorders are not only a pathogenetic link in the development of complications, but they are also observed in patients with early disorders of carbohydrate metabolism and may precede the manifestation of diabetes. However, the method has not yet become widespread in clinical practice.


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