Label-free detection of the carcinoembryonic antibody protein based MoS2 nanosheets using terahertz spectroscopy

2018 ◽  
Author(s):  
Yiwen Sun ◽  
Xingxing Lu ◽  
Pengfei Xie
Keyword(s):  
Terahertz Spectroscopy ◽  
Label Free ◽  
Mos2 Nanosheets ◽  
Label Free Detection

scholarly journals Label-free detection of anti-estrogen receptor alpha and its binding with estrogen receptor peptide alpha by terahertz spectroscopy

RSC Advances ◽  
2017 ◽  
Vol 7 (39) ◽  
pp. 24338-24344 ◽  
Author(s):  
Mingliang Li ◽  
Tianying Chang ◽  
Dongshan Wei ◽  
Mingjie Tang ◽  
Shihan Yan ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Terahertz Spectroscopy ◽  
Hydration Shell ◽  
Spectroscopic Techniques ◽  
Shell Formation ◽  
Label Free ◽  
Binding Reaction ◽  
Receptor Alpha ◽  
Label Free Detection

Terahertz (THz) spectroscopic techniques were employed to study the hydration shell formation around anti-estrogen receptor alpha (AER-α) and to detect the binding reaction between AER-α and estrogen receptor peptide alpha (ERP-α).

Facile synthesis of boron- and nitride-doped MoS2 nanosheets as fluorescent probes for the ultrafast, sensitive, and label-free detection of Hg2+

The Analyst ◽  
2015 ◽  
Vol 140 (13) ◽  
pp. 4654-4661 ◽  
Author(s):  
Xiaojia Liu ◽  
Liping Li ◽  
Yuanjie Wei ◽  
Yizhi Zheng ◽  
Qian Xiao ◽  
...  
Keyword(s):  
Transition Metal ◽  
Band Gap ◽  
Fluorescent Probes ◽  
Label Free ◽  
Mos2 Nanosheets ◽  
Facile Synthesis ◽  
Metal Chalcogenide ◽  
Chalcogenide Material ◽  
Label Free Detection ◽  
Indirect Band Gap

Bulk MoS2, a prototypical transition metal chalcogenide material, is an indirect band gap semiconductor with negligible photoluminescence.

Size-dependent optical extinction of MoS2 nanosheets and their aptamer-induced dispersion behavior for the label-free detection of Escherichia coli O157:H7

The Analyst ◽  
2021 ◽  
Author(s):  
Jiye Li ◽  
Jie Wang
Keyword(s):  
Escherichia Coli ◽  
Escherichia Coli O157 ◽  
Label Free ◽  
Mos2 Nanosheets ◽  
Optical Extinction ◽  
Size Dependent ◽  
Dispersion Behavior ◽  
Label Free Detection ◽  
First Time

For the first time, we have revealed the size-dependent extinction response of MoS2-NS aggregation, the phenomenon of which has been employed as a sensing strategy for the label-free detection of Escherichia coli O157:H7.

The DNA controllable peroxidase mimetic activity of MoS2 nanosheets for constructing a robust colorimetric biosensor

Nanoscale ◽  
2020 ◽  
Vol 12 (37) ◽  
pp. 19420-19428
Author(s):  
Lianjing Zhao ◽  
Jing Wang ◽  
Dandan Su ◽  
Yueying Zhang ◽  
Huiying Lu ◽  
...  
Keyword(s):  
Label Free ◽  
Mos2 Nanosheets ◽  
Peroxidase Mimetic ◽  
Label Free Detection

A robust colorimetric biosensor based on the DNA-controllable peroxidase mimetic activity of MoS2 nanosheets was developed for the label-free detection of CEA.

scholarly journals The Role of Surface Chemistry in the Efficacy of Protein and DNA Microarrays for Label-Free Detection: An Overview

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1026
Author(s):  
Elisa Chiodi ◽  
Allison M. Marn ◽  
Matthew T. Geib ◽  
M. Selim Ünlü
Keyword(s):  
Surface Chemistry ◽  
Surface Functionalization ◽  
Dna Microarrays ◽  
Label Free ◽  
Polymeric Coatings ◽  
Label Free Detection ◽  
Particle Imaging ◽  
Single Particle Imaging ◽  
The Impact

The importance of microarrays in diagnostics and medicine has drastically increased in the last few years. Nevertheless, the efficiency of a microarray-based assay intrinsically depends on the density and functionality of the biorecognition elements immobilized onto each sensor spot. Recently, researchers have put effort into developing new functionalization strategies and technologies which provide efficient immobilization and stability of any sort of molecule. Here, we present an overview of the most widely used methods of surface functionalization of microarray substrates, as well as the most recent advances in the field, and compare their performance in terms of optimal immobilization of the bioreceptor molecules. We focus on label-free microarrays and, in particular, we aim to describe the impact of surface chemistry on two types of microarray-based sensors: microarrays for single particle imaging and for label-free measurements of binding kinetics. Both protein and DNA microarrays are taken into consideration, and the effect of different polymeric coatings on the molecules’ functionalities is critically analyzed.

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