Low cost rapid fabrication of vertical LVOF microspectrometer on-chip for MIR sensing

2018 ◽  
Author(s):  
Shurui Wang ◽  
Simon Chun Kiat Goh ◽  
Li Lynn Shiau ◽  
Nan Chen ◽  
Kailiang Chuan ◽  
...  
Keyword(s):  
Low Cost ◽  
Rapid Fabrication ◽  
On Chip

On-Chip Fabrication of None-Dead-Volume Microtips for ESI-MS Applications

2007 ◽  
Vol 121-123 ◽  
pp. 611-614
Author(s):  
Che Hsin Lin ◽  
Jen Taie Shiea ◽  
Yen Lieng Lin
Keyword(s):  
Surface Tension ◽  
Low Cost ◽  
Microfluidic Channel ◽  
Dead Volume ◽  
Esi Ms ◽  
Rapid Fabrication ◽  
Chip Fabrication ◽  
Novel Method ◽  
On Chip ◽  
Highly Uniform

This paper proposes a novel method to on-chip fabricate a none-dead-volume microtip for ESI-MS applications. The microfluidic chip and ESI tip are fabricated in low-cost plastic based materials using a simple and rapid fabrication process. A constant-speed-pulling method is developed to fabricate the ESI tip by pulling mixed PMMA glue using a 30-μm stainless wire through the pre-formed microfluidic channel. The equilibrium of surface tension of PMMA glue will result in a sharp tip after curing. A highly uniform micro-tip can be formed directly at the outlet of the microfluidic channel with minimum dead-volume zone. Detection of caffeine, myoglobin, lysozyme and cytochrome C biosamples confirms the microchip device can be used for high resolution ESI-MS applications.

scholarly journals Design and Manufacturing of a Disposable, Cyclo-Olefin Copolymer, Microfluidic Device for a Biosensor †

Sensors ◽  
2019 ◽  
Vol 19 (5) ◽  
pp. 1178 ◽  
Author(s):  
Jorge Prada ◽  
Christina Cordes ◽  
Carsten Harms ◽  
Walter Lang
Keyword(s):  
Microfluidic Device ◽  
Heating Temperature ◽  
Low Cost ◽  
Reaction Chamber ◽  
Microfluidic System ◽  
Heating Process ◽  
Design And Manufacturing ◽  
On Chip ◽  
Working Parameters ◽  
Auto Fluorescence

This contribution outlines the design and manufacturing of a microfluidic device implemented as a biosensor for retrieval and detection of bacteria RNA. The device is fully made of Cyclo-Olefin Copolymer (COC), which features low auto-fluorescence, biocompatibility and manufacturability by hot-embossing. The RNA retrieval was carried on after bacteria heat-lysis by an on-chip micro-heater, whose function was characterized at different working parameters. Carbon resistive temperature sensors were tested, characterized and printed on the biochip sealing film to monitor the heating process. Off-chip and on-chip processed RNA were hybridized with capture probes on the reaction chamber surface and identification was achieved by detection of fluorescence tags. The application of the mentioned techniques and materials proved to allow the development of low-cost, disposable albeit multi-functional microfluidic system, performing heating, temperature sensing and chemical reaction processes in the same device. By proving its effectiveness, this device contributes a reference to show the integration potential of fully thermoplastic devices in biosensor systems.

scholarly journals Low-Cost, Large-Area, Facile, and Rapid Fabrication of Aligned ZnO Nanowire Device Arrays

2016 ◽  
Vol 8 (21) ◽  
pp. 13466-13471 ◽  
Author(s):  
Gerard Cadafalch Gazquez ◽  
Sidong Lei ◽  
Antony George ◽  
Hemtej Gullapalli ◽  
Bernard A. Boukamp ◽  
...  
Keyword(s):  
Low Cost ◽  
Zno Nanowire ◽  
Large Area ◽  
Rapid Fabrication ◽  
Nanowire Device

Optical MEMS platform for low-cost on-chip integration of planar light circuits and optical switching

2004 ◽  
Author(s):  
Kristine A. German ◽  
Joel Kubby ◽  
Jingkuang Chen ◽  
James Diehl ◽  
Kathleen Feinberg ◽  
...  
Keyword(s):  
Optical Switching ◽  
Low Cost ◽  
Optical Mems ◽  
On Chip

scholarly journals The Rise of the OM-LoC: Opto-Microfluidic Enabled Lab-on-Chip

Micromachines ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1467
Author(s):  
Harry Dawson ◽  
Jinane Elias ◽  
Pascal Etienne ◽  
Sylvie Calas-Etienne
Keyword(s):  
Low Cost ◽  
Optical Components ◽  
New Era ◽  
Lab On Chip ◽  
Highly Sensitive ◽  
Multiple Challenges ◽  
On Chip ◽  
Optical Circuits ◽  
Made In

The integration of optical circuits with microfluidic lab-on-chip (LoC) devices has resulted in a new era of potential in terms of both sample manipulation and detection at the micro-scale. On-chip optical components increase both control and analytical capabilities while reducing reliance on expensive laboratory photonic equipment that has limited microfluidic development. Notably, in-situ LoC devices for bio-chemical applications such as diagnostics and environmental monitoring could provide great value as low-cost, portable and highly sensitive systems. Multiple challenges remain however due to the complexity involved with combining photonics with micro-fabricated systems. Here, we aim to highlight the progress that optical on-chip systems have made in recent years regarding the main LoC applications: (1) sample manipulation and (2) detection. At the same time, we aim to address the constraints that limit industrial scaling of this technology. Through evaluating various fabrication methods, material choices and novel approaches of optic and fluidic integration, we aim to illustrate how optic-enabled LoC approaches are providing new possibilities for both sample analysis and manipulation.

scholarly journals Tunable laser induced periodic surface structures in Ge2Sb2Te5 thin films

2021 ◽  
Vol 2086 (1) ◽  
pp. 012170
Author(s):  
Irina G Bessonova ◽  
Pavel I Trofimov ◽  
Petr I Lazarenko ◽  
Demid A Kirilenko ◽  
Nikolay A Bert ◽  
...  
Keyword(s):  
Thin Films ◽  
Phase Change ◽  
Low Cost ◽  
Beam Steering ◽  
Tunable Laser ◽  
Surface Structures ◽  
Periodic Surface ◽  
Light Localization ◽  
Rapid Fabrication ◽  
Direct Laser

Abstract Planar photonic structures, such as gratings and metasurfaces, are routinely used for beam steering, waveguide coupling, and light localization. However, conventional fabrication techniques that involve lithography are demanding in terms of time and cost. Much cheaper and simpler methods for surface patterning and formation of periodic surface structures are enabled by direct laser processing. Here, we demonstrate low-cost rapid fabrication of high-quality phase gratings based on the formation of laser induced periodic surface structures (LIPSS, or ripples) in Ge2Sb2Te5 (GST) thin films. Due to unique phase change properties of GST, the structures demonstrate strong modulation of refractive index with period controlled by the wavelength of laser irradiation. We study the formation of phase change LIPSS in a broad range of excitation wavelengths and observe transition between regimes with different orientations of generated ripples with respect to laser polarization.

Low cost optical particle detection for lab on chip systems based on DVD technology

2007 ◽  
Author(s):  
Andrew L. Clow ◽  
Rainer Künnemeyer ◽  
Paul Gaynor ◽  
John C. Sharpe
Keyword(s):  
Low Cost ◽  
Particle Detection ◽  
Lab On Chip ◽  
On Chip

On-chip spectrometer for low-cost optical coherence tomography

2014 ◽  
Author(s):  
Arthur Nitkowski ◽  
Kyle Preston ◽  
Nicolás Sherwood-Droz ◽  
Bradley S. Schmidt ◽  
Arsen R. Hajian
Keyword(s):  
Optical Coherence Tomography ◽  
Low Cost ◽  
Optical Coherence ◽  
On Chip

Rapid fabrication of versatile omni-directional and long-distance three-dimensional flow paper-fluidic analytical devices using a cut-and-insert method for biomedical applications

2018 ◽  
Vol 10 (38) ◽  
pp. 4648-4654 ◽  
Author(s):  
Tae Joon Kwak ◽  
Wookkun Kwon ◽  
Jiang Yang ◽  
Sang Woo Lee ◽  
Woo-Jin Chang
Keyword(s):  
Liquid Flow ◽  
Biomedical Applications ◽  
Low Cost ◽  
Three Dimensional ◽  
Long Distance ◽  
Three Dimensional Flow ◽  
Dimensional Flow ◽  
Rapid Fabrication ◽  
Paper Fluidics ◽  
Cost Regime

Paper fluidics has recently offered an approach to precisely guide liquid flow in analytical devices with a low-cost regime.

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